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The map label for this gene is atpA [H]

Identifier: 192288606

GI number: 192288606

Start: 187660

End: 189192

Strand: Reverse

Name: atpA [H]

Synonym: Rpal_0173

Alternate gene names: 192288606

Gene position: 189192-187660 (Counterclockwise)

Preceding gene: 192288607

Following gene: 192288605

Centisome position: 3.29

GC content: 64.64

Gene sequence:

>1533_bases
ATGGACATCCGCGCCGCGGAAATTTCCGCGATCCTCAAGGACCAGATCAAGAATTTCGGCCAGGAAGCCGAAGTCTCCGA
GGTCGGACAGGTGTTGTCCGTCGGCGACGGTATCGCCCGCGTTTATGGCCTGGATAACGTGCTCGCCGGTGAAATGGTCG
AGTTCGAGAACGGCACCCGCGGCATGGCGCTGAACCTCGAAACCGACAACGTCGGCGTCGTGATCTTCGGTGCCGACCGC
GAGATTAAGGAAGGCCAGACCGTCAAGCGCACCCGTTCGATCGTGGACGCGCCGGTCGGCAAGGGTCTGCTCGGCCGCGT
CGTCGACGCGCTGGGTAACCCGATCGACGGCAAGGGTCCGATCCAGGCGGTCGAGCGCAAGCGCGTCGACGTCAAGGCGC
CCGGCATCATTCCGCGCAAGTCGGTGCACGAGCCGATGGCGACCGGCCTGAAGTCGATCGACGCGCTGATCCCGATCGGT
CGTGGCCAGCGCGAGCTGATCATCGGCGACCGTCAGACCGGCAAGACCGCGATCGCGCTCGACACCATTCTGAACCAGAA
GCCGCTGAACGTCGAAGGCGCGCCGGAGAGCCAGAAGCTCTACTGCGTTTACGTCGCGGTCGGTCAGAAGCGCTCCACCG
TCGCCCAGTTCGTCAAGGTTCTGGAAGAGCAGGGCGCGCTGGAATACTCGGTCGTCGTCGCCGCTACCGCGTCGGACCCG
GCTCCGATGCAGTACATCGCGCCGTTCACCGGCTGCACCATCGGCGAGTACTTCCGCGACAACGGCATGCACGCCGTCAT
CATCTATGACGACTTGTCCAAGCAGGCCGTCGCTTATCGTCAGATGTCGCTGTTGCTGCGCCGCCCGCCGGGCCGCGAAG
CGTATCCGGGCGACGTGTTCTACCTGCACTCCCGTCTGCTCGAGCGCGCCGCCAAGCTCAATGACGAGCAGGGCAACGGC
TCGCTCACCGCGCTGCCGGTGATCGAAACTCAGGCCAACGACGTCTCGGCCTACATTCCGACCAACGTGATCTCGATCAC
CGACGGCCAGATCTTCCTGGAAACCGACCTGTTCTTCCAGGGCATCCGCCCGGCCGTGAACGTCGGTCTGTCGGTGTCGC
GCGTCGGTTCGTCGGCGCAGACCAAGGCGATGAAGAAGGTCGCCGGCAAGATCAAGGGCGAGCTCGCGCAGTACCGCGAA
ATGGCGGCGTTCGCGCAGTTCGGCTCCGACCTCGACGCCGCGACCCAGCGCCTGCTGAACCGCGGTTCGCGCCTGACCGA
ACTCCTGAAGCAGCCGCAGTTCTCGCCGCTGAAGATGGAAGAGCAGGTCTGCGTGATCTGGGCCGGCACCAACGGCTATC
TCGATGCGCTGCCGCTCAACAAGGTGCGCGCGTTCGAAGACGGCCTGCTGGCGCTGCTGCGCGGCAAGGAGTCGGGCATC
CTGGAAGCGATCCGCACCAGCCGCGATCTTTCCGATGACACCGCTGCGAAGCTCAAGGCGGTGGTCGAAAGCTACGCCAA
GACGTTCGCTTGA

Upstream 100 bases:

>100_bases
TCATCGGCGGGCTTGTCGTCAAGCTCGGTAGCCGCATGGTCGACAGTTCGCTCCGCACCAAACTCAATTCGATCAAGCAC
GCGATGAAAGAGGCAGGCTG

Downstream 100 bases:

>100_bases
TGCTGTCATGGCCGGGGTCTTCCCCGGCCATCCACGTCCTCGACGTGGCTATTCGACATCGTGGATGCCCGGGGCGAGCC
CGGGCATGACGAGTGTGAGG

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MDIRAAEISAILKDQIKNFGQEAEVSEVGQVLSVGDGIARVYGLDNVLAGEMVEFENGTRGMALNLETDNVGVVIFGADR
EIKEGQTVKRTRSIVDAPVGKGLLGRVVDALGNPIDGKGPIQAVERKRVDVKAPGIIPRKSVHEPMATGLKSIDALIPIG
RGQRELIIGDRQTGKTAIALDTILNQKPLNVEGAPESQKLYCVYVAVGQKRSTVAQFVKVLEEQGALEYSVVVAATASDP
APMQYIAPFTGCTIGEYFRDNGMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDEQGNG
SLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFQGIRPAVNVGLSVSRVGSSAQTKAMKKVAGKIKGELAQYRE
MAAFAQFGSDLDAATQRLLNRGSRLTELLKQPQFSPLKMEEQVCVIWAGTNGYLDALPLNKVRAFEDGLLALLRGKESGI
LEAIRTSRDLSDDTAAKLKAVVESYAKTFA

Sequences:

>Translated_510_residues
MDIRAAEISAILKDQIKNFGQEAEVSEVGQVLSVGDGIARVYGLDNVLAGEMVEFENGTRGMALNLETDNVGVVIFGADR
EIKEGQTVKRTRSIVDAPVGKGLLGRVVDALGNPIDGKGPIQAVERKRVDVKAPGIIPRKSVHEPMATGLKSIDALIPIG
RGQRELIIGDRQTGKTAIALDTILNQKPLNVEGAPESQKLYCVYVAVGQKRSTVAQFVKVLEEQGALEYSVVVAATASDP
APMQYIAPFTGCTIGEYFRDNGMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDEQGNG
SLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFQGIRPAVNVGLSVSRVGSSAQTKAMKKVAGKIKGELAQYRE
MAAFAQFGSDLDAATQRLLNRGSRLTELLKQPQFSPLKMEEQVCVIWAGTNGYLDALPLNKVRAFEDGLLALLRGKESGI
LEAIRTSRDLSDDTAAKLKAVVESYAKTFA
>Mature_510_residues
MDIRAAEISAILKDQIKNFGQEAEVSEVGQVLSVGDGIARVYGLDNVLAGEMVEFENGTRGMALNLETDNVGVVIFGADR
EIKEGQTVKRTRSIVDAPVGKGLLGRVVDALGNPIDGKGPIQAVERKRVDVKAPGIIPRKSVHEPMATGLKSIDALIPIG
RGQRELIIGDRQTGKTAIALDTILNQKPLNVEGAPESQKLYCVYVAVGQKRSTVAQFVKVLEEQGALEYSVVVAATASDP
APMQYIAPFTGCTIGEYFRDNGMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDEQGNG
SLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFQGIRPAVNVGLSVSRVGSSAQTKAMKKVAGKIKGELAQYRE
MAAFAQFGSDLDAATQRLLNRGSRLTELLKQPQFSPLKMEEQVCVIWAGTNGYLDALPLNKVRAFEDGLLALLRGKESGI
LEAIRTSRDLSDDTAAKLKAVVESYAKTFA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=504, Percent_Identity=69.2460317460317, Blast_Score=718, Evalue=0.0,
Organism=Homo sapiens, GI4757810, Length=504, Percent_Identity=69.2460317460317, Blast_Score=718, Evalue=0.0,
Organism=Homo sapiens, GI19913428, Length=340, Percent_Identity=28.8235294117647, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI19913426, Length=317, Percent_Identity=29.0220820189274, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI32189394, Length=393, Percent_Identity=24.4274809160305, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI19913424, Length=249, Percent_Identity=26.1044176706827, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1790172, Length=519, Percent_Identity=53.757225433526, Blast_Score=561, Evalue=1e-161,
Organism=Escherichia coli, GI1790170, Length=438, Percent_Identity=24.4292237442922, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788251, Length=388, Percent_Identity=27.5773195876289, Blast_Score=101, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=504, Percent_Identity=68.8492063492064, Blast_Score=715, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988080, Length=504, Percent_Identity=68.8492063492064, Blast_Score=714, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988074, Length=504, Percent_Identity=63.8888888888889, Blast_Score=650, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17570191, Length=331, Percent_Identity=27.4924471299094, Blast_Score=119, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17510931, Length=304, Percent_Identity=28.6184210526316, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI25144756, Length=394, Percent_Identity=24.1116751269036, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71988068, Length=76, Percent_Identity=55.2631578947368, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=62, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17565854, Length=263, Percent_Identity=25.4752851711027, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319370, Length=503, Percent_Identity=68.7872763419483, Blast_Score=720, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=367, Percent_Identity=29.700272479564, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6322581, Length=430, Percent_Identity=25.3488372093023, Blast_Score=103, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24658560, Length=506, Percent_Identity=68.9723320158103, Blast_Score=712, Evalue=0.0,
Organism=Drosophila melanogaster, GI281361666, Length=303, Percent_Identity=29.3729372937294, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24646341, Length=303, Percent_Identity=29.3729372937294, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17136796, Length=303, Percent_Identity=29.3729372937294, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28574560, Length=430, Percent_Identity=25.8139534883721, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24638766, Length=415, Percent_Identity=24.0963855421687, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24583992, Length=251, Percent_Identity=25.4980079681275, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24583988, Length=251, Percent_Identity=25.4980079681275, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583986, Length=251, Percent_Identity=25.4980079681275, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583984, Length=251, Percent_Identity=25.4980079681275, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20129479, Length=251, Percent_Identity=27.4900398406374, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55178; Mature: 55178

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIRAAEISAILKDQIKNFGQEAEVSEVGQVLSVGDGIARVYGLDNVLAGEMVEFENGTR
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHCCCHHHHCCEEEECCCCC
GMALNLETDNVGVVIFGADREIKEGQTVKRTRSIVDAPVGKGLLGRVVDALGNPIDGKGP
CEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC
IQAVERKRVDVKAPGIIPRKSVHEPMATGLKSIDALIPIGRGQRELIIGDRQTGKTAIAL
HHHHHHCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEH
DTILNQKPLNVEGAPESQKLYCVYVAVGQKRSTVAQFVKVLEEQGALEYSVVVAATASDP
HHHHCCCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCC
APMQYIAPFTGCTIGEYFRDNGMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVF
CCCCEECCCCCCCHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHH
YLHSRLLERAAKLNDEQGNGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFQ
HHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEHHHHH
GIRPAVNVGLSVSRVGSSAQTKAMKKVAGKIKGELAQYREMAAFAQFGSDLDAATQRLLN
CCCHHHHCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RGSRLTELLKQPQFSPLKMEEQVCVIWAGTNGYLDALPLNKVRAFEDGLLALLRGKESGI
CCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCEECCCCHHHHHHHHHHHHHHCCCCCHH
LEAIRTSRDLSDDTAAKLKAVVESYAKTFA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDIRAAEISAILKDQIKNFGQEAEVSEVGQVLSVGDGIARVYGLDNVLAGEMVEFENGTR
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHCCCHHHHCCEEEECCCCC
GMALNLETDNVGVVIFGADREIKEGQTVKRTRSIVDAPVGKGLLGRVVDALGNPIDGKGP
CEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC
IQAVERKRVDVKAPGIIPRKSVHEPMATGLKSIDALIPIGRGQRELIIGDRQTGKTAIAL
HHHHHHCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEH
DTILNQKPLNVEGAPESQKLYCVYVAVGQKRSTVAQFVKVLEEQGALEYSVVVAATASDP
HHHHCCCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCC
APMQYIAPFTGCTIGEYFRDNGMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVF
CCCCEECCCCCCCHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHH
YLHSRLLERAAKLNDEQGNGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFQ
HHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEHHHHH
GIRPAVNVGLSVSRVGSSAQTKAMKKVAGKIKGELAQYREMAAFAQFGSDLDAATQRLLN
CCCHHHHCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RGSRLTELLKQPQFSPLKMEEQVCVIWAGTNGYLDALPLNKVRAFEDGLLALLRGKESGI
CCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCEECCCCHHHHHHHHHHHHHHCCCCCHH
LEAIRTSRDLSDDTAAKLKAVVESYAKTFA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA