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The map label for this gene is dppB [H]

Identifier: 192288538

GI number: 192288538

Start: 114274

End: 115254

Strand: Reverse

Name: dppB [H]

Synonym: Rpal_0105

Alternate gene names: 192288538

Gene position: 115254-114274 (Counterclockwise)

Preceding gene: 192288539

Following gene: 192288537

Centisome position: 2.01

GC content: 65.95

Gene sequence:

>981_bases
ATGGCTCTCCTCACCCATCTGTTCGGAAAACTCGCCAACGCCGTCGCGCTGCTGCTGGCGGTGCTGGTGATGAATTTCTG
CCTGATCCATCTTGCGCCGGGCGACCCGGTGCAGGTGATCGCCGGCGAGATGGGTGGGGCGTCGCCCGAGGTGATCGCGG
CGCTGCGGGCAAAATACGGCCTCGACCACAGCCTGCTCGAACAGATGTTCACTTATCTGGGCAAGGTGGCGCATGGCGAC
TTCGGCTATTCCTACTACTTCAACCAGCCGGTGCTCGGCCTGATCCTGCAGCGGCTGCCCGCGACGCTGTATCTGGCGGC
GGCCTCGCTGGTGGTGGCGGTGCTGATCGGCACGGTGCTCGGCGTGATCAGCGCCCGGCGCCCGAACGGCCTGCTCAGCC
ACGGCGTCACCGTGCTGTCGCTCGCCGGTCACGCGGCGCCGATCTTCTGGACCGGCCTGCTGCTTCTGCTGCTGTTCGGA
TCGGTGTGGCCGATCCTGCCGGTCAACGGCATGACCGACGTGGTCAATCCAAAAACCGGCTTCGCCTATGCGGCCGACGT
CGCCAAGCATCTGGTGCTGCCGTCGATCACGCTGGGGCTGGTATTCGTCGCGCAATATTCCCGGCTCGCCCGCGTCAACA
TGATCGACGTGCTGTCGGCGGACTACATCCGCACCGCGCGCGCCAAGGGGCTGCCGGAGCGGGTGGTGCTGGTCAAGCAC
GCGCTGCGCAACACGCTGATTCCGATCGTCACCGTGGTCGGCCTGCAGTTCGGCAATCTGTTCGCCGGCGCCGTGCTGGT
GGAGACGGTGTACTCCTGGCCGGGCATGGGGCGGCTGGTGTTCGACTCGATCCTGCGCCGTGACTACCCGACGCTGATGG
GCGTGCTGTTCTTCTCCGCCGTGATGGTGATCGCGGCCAACATCCTCACCGACCTGGTGTACCGCCTGATCGATCCCCGT
ATCCGCGCAGGTGCCCGATGA

Upstream 100 bases:

>100_bases
CTGCCGACCACGGTGTGGGGCGTCGCCTCGCCGCTCGACGAGCTGTACTGGGTGACTCCGCCGAAGAACTGATCCGCCAA
TCTCGATCGACAGAGCATCA

Downstream 100 bases:

>100_bases
GCACGATGGAGTCTTCGCTCGCGATGGCACAGAAGCCCCTTCCCAGCGTCAGCAAAGTGCCGAAGGCTGTCTCGCCAGCC
CGGGCTGCGCTGCGCCAGTT

Product: ABC transporter inner membrane protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MALLTHLFGKLANAVALLLAVLVMNFCLIHLAPGDPVQVIAGEMGGASPEVIAALRAKYGLDHSLLEQMFTYLGKVAHGD
FGYSYYFNQPVLGLILQRLPATLYLAAASLVVAVLIGTVLGVISARRPNGLLSHGVTVLSLAGHAAPIFWTGLLLLLLFG
SVWPILPVNGMTDVVNPKTGFAYAADVAKHLVLPSITLGLVFVAQYSRLARVNMIDVLSADYIRTARAKGLPERVVLVKH
ALRNTLIPIVTVVGLQFGNLFAGAVLVETVYSWPGMGRLVFDSILRRDYPTLMGVLFFSAVMVIAANILTDLVYRLIDPR
IRAGAR

Sequences:

>Translated_326_residues
MALLTHLFGKLANAVALLLAVLVMNFCLIHLAPGDPVQVIAGEMGGASPEVIAALRAKYGLDHSLLEQMFTYLGKVAHGD
FGYSYYFNQPVLGLILQRLPATLYLAAASLVVAVLIGTVLGVISARRPNGLLSHGVTVLSLAGHAAPIFWTGLLLLLLFG
SVWPILPVNGMTDVVNPKTGFAYAADVAKHLVLPSITLGLVFVAQYSRLARVNMIDVLSADYIRTARAKGLPERVVLVKH
ALRNTLIPIVTVVGLQFGNLFAGAVLVETVYSWPGMGRLVFDSILRRDYPTLMGVLFFSAVMVIAANILTDLVYRLIDPR
IRAGAR
>Mature_325_residues
ALLTHLFGKLANAVALLLAVLVMNFCLIHLAPGDPVQVIAGEMGGASPEVIAALRAKYGLDHSLLEQMFTYLGKVAHGDF
GYSYYFNQPVLGLILQRLPATLYLAAASLVVAVLIGTVLGVISARRPNGLLSHGVTVLSLAGHAAPIFWTGLLLLLLFGS
VWPILPVNGMTDVVNPKTGFAYAADVAKHLVLPSITLGLVFVAQYSRLARVNMIDVLSADYIRTARAKGLPERVVLVKHA
LRNTLIPIVTVVGLQFGNLFAGAVLVETVYSWPGMGRLVFDSILRRDYPTLMGVLFFSAVMVIAANILTDLVYRLIDPRI
RAGAR

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=337, Percent_Identity=39.7626112759644, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI1787053, Length=320, Percent_Identity=37.8125, Blast_Score=214, Evalue=4e-57,
Organism=Escherichia coli, GI1787497, Length=321, Percent_Identity=33.3333333333333, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1787761, Length=341, Percent_Identity=39.0029325513196, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1789888, Length=309, Percent_Identity=33.0097087378641, Blast_Score=174, Evalue=9e-45,
Organism=Escherichia coli, GI1788504, Length=361, Percent_Identity=27.7008310249307, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1787550, Length=273, Percent_Identity=29.3040293040293, Blast_Score=135, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35065; Mature: 34934

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLTHLFGKLANAVALLLAVLVMNFCLIHLAPGDPVQVIAGEMGGASPEVIAALRAKYG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHHC
LDHSLLEQMFTYLGKVAHGDFGYSYYFNQPVLGLILQRLPATLYLAAASLVVAVLIGTVL
CCHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVISARRPNGLLSHGVTVLSLAGHAAPIFWTGLLLLLLFGSVWPILPVNGMTDVVNPKTG
HHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
FAYAADVAKHLVLPSITLGLVFVAQYSRLARVNMIDVLSADYIRTARAKGLPERVVLVKH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ALRNTLIPIVTVVGLQFGNLFAGAVLVETVYSWPGMGRLVFDSILRRDYPTLMGVLFFSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHH
VMVIAANILTDLVYRLIDPRIRAGAR
HHHHHHHHHHHHHHHHHCHHHHCCCC
>Mature Secondary Structure 
ALLTHLFGKLANAVALLLAVLVMNFCLIHLAPGDPVQVIAGEMGGASPEVIAALRAKYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHHC
LDHSLLEQMFTYLGKVAHGDFGYSYYFNQPVLGLILQRLPATLYLAAASLVVAVLIGTVL
CCHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVISARRPNGLLSHGVTVLSLAGHAAPIFWTGLLLLLLFGSVWPILPVNGMTDVVNPKTG
HHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
FAYAADVAKHLVLPSITLGLVFVAQYSRLARVNMIDVLSADYIRTARAKGLPERVVLVKH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ALRNTLIPIVTVVGLQFGNLFAGAVLVETVYSWPGMGRLVFDSILRRDYPTLMGVLFFSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHH
VMVIAANILTDLVYRLIDPRIRAGAR
HHHHHHHHHHHHHHHHHCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]