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The map label for this gene is appC [H]

Identifier: 192288537

GI number: 192288537

Start: 113369

End: 114277

Strand: Reverse

Name: appC [H]

Synonym: Rpal_0104

Alternate gene names: 192288537

Gene position: 114277-113369 (Counterclockwise)

Preceding gene: 192288538

Following gene: 192288536

Centisome position: 1.99

GC content: 68.21

Gene sequence:

>909_bases
ATGAGCACGATGGAGTCTTCGCTCGCGATGGCACAGAAGCCCCTTCCCAGCGTCAGCAAAGTGCCGAAGGCTGTCTCGCC
AGCCCGGGCTGCGCTGCGCCAGTTCATGAAGAGTCCGTCCGGCGTCGCCGGCGCACTCCTGCTCCTGCTGCTGCTCGCCG
GCACCGCGCTCGGCCCGTGGCTGCATCCGGTCGATCCGCTCGACATCGTCGGCCTGCCGTTTGCCGCGCCGGCGGCCGAT
GCTCCGCTCGGCACCGACTATCTTGGCCGCGACGTGCTGGCCGGGCTGATCTATGGCGGCCGGGCGACGCTGACGGTGGG
CGCCGTGGCGGCGCTGATCACGATCGTGATCGGAGTCACCGTCGGAGCGCTTGCCGGCTTCTTCGGCGGCTGGGTCGATG
CGCTCCTGGTCAAGATCGCCGAGTTCTTTCAGGTGCTGCCGCCGCTGCTGTTTGCAATGGTGCTGGTGACGCTGTTCGGC
CCCAAGCTGTCGACCATCACGCTGGCGATCGGCGCGGTGAGCTGGACCTCGGCCGCGCGGTTGACGCGCGCCGAATTCAT
GCGGCTGCGGGATCTCGATTTCATCAAGGCCTCGCGCGCCGCCGGTGCCGGCAGTCTGCATCTGATCCTGCGCGTGGTGC
TGCCGAATGCGCTGCCGCCGATTATCGTGTCGGCGACGCTGGCGATCGGCACCGCGATCCTGTTCGAGGGAGGCCTCAGC
TTCCTCGGTCTCGGCGATCCCAACACCATGAGCTGGGGCCTGATGATCGGCCAGAACCGCAACTACGTGCTCGACGCCTG
GTGGGCGGTGACGTTCCCCGGCGCCGCGATCTTTCTTGCCGTGCTCGCGGTCAGCCTGGTCGGCGACGGCGTCAACGATG
CGGTCAATCCGCGCCTGCGGCGGAGGTGA

Upstream 100 bases:

>100_bases
TGGGCGTGCTGTTCTTCTCCGCCGTGATGGTGATCGCGGCCAACATCCTCACCGACCTGGTGTACCGCCTGATCGATCCC
CGTATCCGCGCAGGTGCCCG

Downstream 100 bases:

>100_bases
TGATGGCGCCGGTCCTATCAGTCGAGAATCTCAGCGTCAGCATGACCAATCGCGACGGCGATCTGGTGCCGGTGCTGGAG
AATCTGTCTTTCACGGTTCA

Product: ABC transporter inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MSTMESSLAMAQKPLPSVSKVPKAVSPARAALRQFMKSPSGVAGALLLLLLLAGTALGPWLHPVDPLDIVGLPFAAPAAD
APLGTDYLGRDVLAGLIYGGRATLTVGAVAALITIVIGVTVGALAGFFGGWVDALLVKIAEFFQVLPPLLFAMVLVTLFG
PKLSTITLAIGAVSWTSAARLTRAEFMRLRDLDFIKASRAAGAGSLHLILRVVLPNALPPIIVSATLAIGTAILFEGGLS
FLGLGDPNTMSWGLMIGQNRNYVLDAWWAVTFPGAAIFLAVLAVSLVGDGVNDAVNPRLRRR

Sequences:

>Translated_302_residues
MSTMESSLAMAQKPLPSVSKVPKAVSPARAALRQFMKSPSGVAGALLLLLLLAGTALGPWLHPVDPLDIVGLPFAAPAAD
APLGTDYLGRDVLAGLIYGGRATLTVGAVAALITIVIGVTVGALAGFFGGWVDALLVKIAEFFQVLPPLLFAMVLVTLFG
PKLSTITLAIGAVSWTSAARLTRAEFMRLRDLDFIKASRAAGAGSLHLILRVVLPNALPPIIVSATLAIGTAILFEGGLS
FLGLGDPNTMSWGLMIGQNRNYVLDAWWAVTFPGAAIFLAVLAVSLVGDGVNDAVNPRLRRR
>Mature_301_residues
STMESSLAMAQKPLPSVSKVPKAVSPARAALRQFMKSPSGVAGALLLLLLLAGTALGPWLHPVDPLDIVGLPFAAPAADA
PLGTDYLGRDVLAGLIYGGRATLTVGAVAALITIVIGVTVGALAGFFGGWVDALLVKIAEFFQVLPPLLFAMVLVTLFGP
KLSTITLAIGAVSWTSAARLTRAEFMRLRDLDFIKASRAAGAGSLHLILRVVLPNALPPIIVSATLAIGTAILFEGGLSF
LGLGDPNTMSWGLMIGQNRNYVLDAWWAVTFPGAAIFLAVLAVSLVGDGVNDAVNPRLRRR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=293, Percent_Identity=36.518771331058, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1789964, Length=300, Percent_Identity=37, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1787054, Length=285, Percent_Identity=32.9824561403509, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1789889, Length=243, Percent_Identity=34.5679012345679, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1787498, Length=277, Percent_Identity=34.2960288808664, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1788505, Length=229, Percent_Identity=33.1877729257642, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787549, Length=295, Percent_Identity=31.1864406779661, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31426; Mature: 31295

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTMESSLAMAQKPLPSVSKVPKAVSPARAALRQFMKSPSGVAGALLLLLLLAGTALGPW
CCCHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
LHPVDPLDIVGLPFAAPAADAPLGTDYLGRDVLAGLIYGGRATLTVGAVAALITIVIGVT
CCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VGALAGFFGGWVDALLVKIAEFFQVLPPLLFAMVLVTLFGPKLSTITLAIGAVSWTSAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LTRAEFMRLRDLDFIKASRAAGAGSLHLILRVVLPNALPPIIVSATLAIGTAILFEGGLS
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
FLGLGDPNTMSWGLMIGQNRNYVLDAWWAVTFPGAAIFLAVLAVSLVGDGVNDAVNPRLR
EEECCCCCCEEEEEEEECCCCEEEEEHHHHHCCHHHHHHHHHHHHHHCCCCCHHCCCHHC
RR
CC
>Mature Secondary Structure 
STMESSLAMAQKPLPSVSKVPKAVSPARAALRQFMKSPSGVAGALLLLLLLAGTALGPW
CCHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
LHPVDPLDIVGLPFAAPAADAPLGTDYLGRDVLAGLIYGGRATLTVGAVAALITIVIGVT
CCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VGALAGFFGGWVDALLVKIAEFFQVLPPLLFAMVLVTLFGPKLSTITLAIGAVSWTSAAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LTRAEFMRLRDLDFIKASRAAGAGSLHLILRVVLPNALPPIIVSATLAIGTAILFEGGLS
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
FLGLGDPNTMSWGLMIGQNRNYVLDAWWAVTFPGAAIFLAVLAVSLVGDGVNDAVNPRLR
EEECCCCCCEEEEEEEECCCCEEEEEHHHHHCCHHHHHHHHHHHHHHCCCCCHHCCCHHC
RR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]