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The map label for this gene is virB10c [H]

Identifier: 190895228

GI number: 190895228

Start: 991868

End: 993043

Strand: Reverse

Name: virB10c [H]

Synonym: RHECIAT_PC0000901

Alternate gene names: 190895228

Gene position: 993043-991868 (Counterclockwise)

Preceding gene: 190895229

Following gene: 190895227

Centisome position: 90.98

GC content: 64.71

Gene sequence:

>1176_bases
ATGGTCGAGGAAGAGATTATCCAGATCCCCGGTGAGCGCGCCGAGACGTCGGCCGGCGGCCGGCTCGACAACAATCCCAT
CCTCAAACGCGGCGCTGTCGCTGTCGCGATGGTGGTCTTTGTCGCCTTCGCGCTCTGGTCGATGCGCGGGCAGGACAAAC
CGTCGGATAGTGCCCAGCCCGAACGGGTGGTCATCCGCCAGACTTCGGATTTCGAACCGGCCAAGGAGCCGGTCCAGCCG
ACAGCGACTCTGCCGCAGGTCCAGCTCCCGACGCCTGTTGCTACCGAACAGGCGCCGACGGACGATGACAAACTGCTCGA
TGCTGCCCGCCGTGCGCCGGTCATCGCTTATGGCGGCGAGAAGGCGCCGTCGACTCGGCGCCAGGATCAGGACAGGACCT
CGGATCAAGCCTCGGACTACGTGCAGCTCGGCGCCAATCCCGGCGGCTTCGCCTCGCAGGGCGAAAACGAAGACCAGCGC
TTCAGCCGCTTGCTGACGCCGACGCAGTTGCAGGGATCGCGCGCCGGCACGCTGGGCAACCGCGATTTCATCGTCGCGAT
GGGGACATCCATTCCTTGCGTTCTCGAGACCGCGCTCTCCTCCGATCAGCCGGGGTTCACCAGCTGCGTCATCAACCGCG
ACGTTCTTTCGGATAACGGCCGCGTCGTGCTGATGGAAAAAGGCACGCAGGTCGTCGGTGAATATCGCGGCGGCATCCGC
CGTGGACAGAAGCGCCTGTTCGTCCTCTGGAACCGGGCGAAGACCCCGAAGGGCGTGATCATCACTTTGGCGTCGCCGGC
AACCGATGCCCTCGGCCGGGCCGGCGTCGACGGCTATGTCGACACCCATTGGTGGGAGCGTTTCGGCAGCGCGATCCTGC
TGTCGATCGTCGGCGACACGACCTCCTACGCCAGCAGCCGGCTGCAGGACAGCGATGTCGAAGCGCAAAACACCACCAGC
GCCGGCCAGCAGGCCGCGGCGATCGCCGTCGAGCAATCGATCAACATTGCGCCGACCCTCATGAAGCATCAGGGCGAGCT
GGTTTCGATCTTCGTCGCGCGTGATCTCGATTTCTCCAGCGTCTACCGGCTTCGCGTAACGGAGCCCGGCAACCGCATCT
ACGACCGCGCCGTGCTCGGAGATTTCGCGCCGACGTCGAAGATCGTGACAAAATAG

Upstream 100 bases:

>100_bases
AAGCCTACGATCGCGTCGGCATCAATCCCGAGACCAACACGACGTCACCGTCGGTCAAGCGCGTCGTCAAGGCGCCGCAA
GATGCGCAATAGGAGGGGGC

Downstream 100 bases:

>100_bases
GTTCGACGATGACCGAAGCTCCGGACTCCGCAGTCGTGCGCGAATTGCTTTCGCCTCTCTCGCCGTTCCTTCGCGACAAG
ACGTTCTATGAGGTCATCGT

Product: transport secretion system IV protein, VirB10

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MVEEEIIQIPGERAETSAGGRLDNNPILKRGAVAVAMVVFVAFALWSMRGQDKPSDSAQPERVVIRQTSDFEPAKEPVQP
TATLPQVQLPTPVATEQAPTDDDKLLDAARRAPVIAYGGEKAPSTRRQDQDRTSDQASDYVQLGANPGGFASQGENEDQR
FSRLLTPTQLQGSRAGTLGNRDFIVAMGTSIPCVLETALSSDQPGFTSCVINRDVLSDNGRVVLMEKGTQVVGEYRGGIR
RGQKRLFVLWNRAKTPKGVIITLASPATDALGRAGVDGYVDTHWWERFGSAILLSIVGDTTSYASSRLQDSDVEAQNTTS
AGQQAAAIAVEQSINIAPTLMKHQGELVSIFVARDLDFSSVYRLRVTEPGNRIYDRAVLGDFAPTSKIVTK

Sequences:

>Translated_391_residues
MVEEEIIQIPGERAETSAGGRLDNNPILKRGAVAVAMVVFVAFALWSMRGQDKPSDSAQPERVVIRQTSDFEPAKEPVQP
TATLPQVQLPTPVATEQAPTDDDKLLDAARRAPVIAYGGEKAPSTRRQDQDRTSDQASDYVQLGANPGGFASQGENEDQR
FSRLLTPTQLQGSRAGTLGNRDFIVAMGTSIPCVLETALSSDQPGFTSCVINRDVLSDNGRVVLMEKGTQVVGEYRGGIR
RGQKRLFVLWNRAKTPKGVIITLASPATDALGRAGVDGYVDTHWWERFGSAILLSIVGDTTSYASSRLQDSDVEAQNTTS
AGQQAAAIAVEQSINIAPTLMKHQGELVSIFVARDLDFSSVYRLRVTEPGNRIYDRAVLGDFAPTSKIVTK
>Mature_391_residues
MVEEEIIQIPGERAETSAGGRLDNNPILKRGAVAVAMVVFVAFALWSMRGQDKPSDSAQPERVVIRQTSDFEPAKEPVQP
TATLPQVQLPTPVATEQAPTDDDKLLDAARRAPVIAYGGEKAPSTRRQDQDRTSDQASDYVQLGANPGGFASQGENEDQR
FSRLLTPTQLQGSRAGTLGNRDFIVAMGTSIPCVLETALSSDQPGFTSCVINRDVLSDNGRVVLMEKGTQVVGEYRGGIR
RGQKRLFVLWNRAKTPKGVIITLASPATDALGRAGVDGYVDTHWWERFGSAILLSIVGDTTSYASSRLQDSDVEAQNTTS
AGQQAAAIAVEQSINIAPTLMKHQGELVSIFVARDLDFSSVYRLRVTEPGNRIYDRAVLGDFAPTSKIVTK

Specific function: Component of the type IV secretion system virB/virD4 which could be a major virulence determinant for subversion of human endothelial cell (HEC) function [H]

COG id: COG2948

COG function: function code U; Type IV secretory pathway, VirB10 components

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trbI/virB10 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005498 [H]

Pfam domain/function: PF03743 TrbI [H]

EC number: NA

Molecular weight: Translated: 42275; Mature: 42275

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEEEIIQIPGERAETSAGGRLDNNPILKRGAVAVAMVVFVAFALWSMRGQDKPSDSAQP
CCCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ERVVIRQTSDFEPAKEPVQPTATLPQVQLPTPVATEQAPTDDDKLLDAARRAPVIAYGGE
CEEEEEECCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHCCEEEECCC
KAPSTRRQDQDRTSDQASDYVQLGANPGGFASQGENEDQRFSRLLTPTQLQGSRAGTLGN
CCCCCCCCHHHHCHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
RDFIVAMGTSIPCVLETALSSDQPGFTSCVINRDVLSDNGRVVLMEKGTQVVGEYRGGIR
CCEEEEECCCCCHHHHHHHCCCCCCCEEEEEEHHHCCCCCCEEEEECCCHHHHHHHHHHH
RGQKRLFVLWNRAKTPKGVIITLASPATDALGRAGVDGYVDTHWWERFGSAILLSIVGDT
HCCCEEEEEEECCCCCCCEEEEECCCCHHHHHCCCCCCCCCHHHHHHHCCEEEEEECCCC
TSYASSRLQDSDVEAQNTTSAGQQAAAIAVEQSINIAPTLMKHQGELVSIFVARDLDFSS
HHHHHHHCCCCCCCCCCCCCCCHHHHEEEECCCCCCCHHHHHCCCCEEEEEEECCCCHHH
VYRLRVTEPGNRIYDRAVLGDFAPTSKIVTK
EEEEEEECCCCHHHHHHHHCCCCCCCHHCCC
>Mature Secondary Structure
MVEEEIIQIPGERAETSAGGRLDNNPILKRGAVAVAMVVFVAFALWSMRGQDKPSDSAQP
CCCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ERVVIRQTSDFEPAKEPVQPTATLPQVQLPTPVATEQAPTDDDKLLDAARRAPVIAYGGE
CEEEEEECCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHCCEEEECCC
KAPSTRRQDQDRTSDQASDYVQLGANPGGFASQGENEDQRFSRLLTPTQLQGSRAGTLGN
CCCCCCCCHHHHCHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
RDFIVAMGTSIPCVLETALSSDQPGFTSCVINRDVLSDNGRVVLMEKGTQVVGEYRGGIR
CCEEEEECCCCCHHHHHHHCCCCCCCEEEEEEHHHCCCCCCEEEEECCCHHHHHHHHHHH
RGQKRLFVLWNRAKTPKGVIITLASPATDALGRAGVDGYVDTHWWERFGSAILLSIVGDT
HCCCEEEEEEECCCCCCCEEEEECCCCHHHHHCCCCCCCCCHHHHHHHCCEEEEEECCCC
TSYASSRLQDSDVEAQNTTSAGQQAAAIAVEQSINIAPTLMKHQGELVSIFVARDLDFSS
HHHHHHHCCCCCCCCCCCCCCCHHHHEEEECCCCCCCHHHHHCCCCEEEEEEECCCCHHH
VYRLRVTEPGNRIYDRAVLGDFAPTSKIVTK
EEEEEEECCCCHHHHHHHHCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA