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The map label for this gene is 190895145

Identifier: 190895145

GI number: 190895145

Start: 876033

End: 877676

Strand: Reverse

Name: 190895145

Synonym: RHECIAT_PC0000815

Alternate gene names: NA

Gene position: 877676-876033 (Counterclockwise)

Preceding gene: 190895146

Following gene: 190895144

Centisome position: 80.41

GC content: 59.31

Gene sequence:

>1644_bases
ATGACACAGAAACGCGATGCAATCGCCGAGATGCGGCTCCAGATCATGTGGAACAGGCTCATCTCCGTCGTCGAAGAGCA
GGCTCTGACACTGGTGCGCACCGCTTTTAGCACGAGCGTGCGGGAGGCGGGTGACCTTTCAGCCGGTGTATTCAATATTG
CCGGTGAAATGGTCGCACAGGCCGTAACGGGAACGCCCGGACACGTGAACGCCATGGGCGAAGCCGTAAGTCATTTCATC
AACACGATCGGACGCGACAATATTTTCGAGGGCGATGTCTACATCACCAACGATCCCTGGAAGGGTACCGGACATCTACA
CGACTTCACGGTCGTCAGCCCATCCTTCCACAAGGGTAGCCTGATAGGCTTTTTCGCATGCACCGCGCACGTCGTCGATG
TCGGCGGACGCGGCTTCGGACCCGACGCTGGTGAAGTGTACGAAGAAGGCATTTTCATCCCGATCATGAAGTTCGCGGAG
CGAGGCGCAGTAAACCGCGATCTGATCAACATCGTTCGTAACAACGTACGCGAAGCCGACCAGGTCGTCGGAGACCTGTA
TTCGCTCGCCGCCTGCAACGAGATCGGCCACAAGCGGCTTCTCGAAATGCTCGCGGAATTCGATATTGCCGATATCGAGG
ATCTTGCGAAGTTCATCTTCGATCACTCCTACCAGGCTACCGTCGACCGCATCGCCGAACTGCCCGCAGGTATCTACCGC
AACTCGATGCGCGTGGACGGCTACGGATCGGCGATCGACATGGTCGTAAAGCTCGATGTGCGGAAGGACGAAATCATCGC
CGACTTCGATGGTACATCGCCGCCCAGTCCCCTCGGCATCAACGTCCCGCTGATCTATACGACGGCATACGCCGCATACG
GCTTGAAATGCTCGCTGGCACCGGAGATTCCAAACAATGCGGCGTCCCTGAAGCCATTCAGGATCATTGCACCGGAGAAT
TGCATTTTGAATGCGCAGCGACCAGCGCCGGTCGCTGTTCGCCACGTACTCGGTCACTTCGTTCCGGATACCGTGCTCGG
CGCAGTCCATAAGATGCTGCCCGACACGGTTCCGGCGGAAGGCGCTGGCGCCCTGTGGAATATCCACCTCAGTGCCCGCC
CGTCTCAAGGCCGTGCAGCCAACGGCTTCGATCTGCACCGCACCGAGATCCTGATGTTCAATTCCGGCGGAAGCGGTGCT
CGCCCAACGCTCGACGGTCTCAATGCGACTGCTTTTCCAAGCGGCGTTCACAGCATGTCGGTGGAAGCAACCGAGCACGT
GGGCCCGGTCATCGTTTGGCGCAAAGAATTGCGAAATGGATCGGGCGGCGAGGGGCGCCAGCGCGGCGGCCTTGGTCAAG
TCGTTGAGATCGCACCGACGGACGGTCATGAATTCTACTTCAACGCCATGTTCGACCGAGTCGAAAACGCGGCGAGGGGC
CGGGAAGGGGGCGAAAATGGCGCCTCGGGCCGCGCCTATCTCAACGACGGCACCGCCCTGAATGCAAAGGGCCGGCAGTT
CGTCCCAGAAGGCAAAAGACTGGTTATCGAGCTTCCCGGCGGCGGTGGCTATGGCAAGCCCGACGATAGGCCGCACGAAG
CAGTCGAACGGGATCGTCTCGACCAGTATGTCGTTTCGAAGTGA

Upstream 100 bases:

>100_bases
GAGCGGGAAACGACCACGATCATCTCGTCATCCTACGAGGCGATCATGCAGCCCGATGGCTGCCTGCTTGTGACTGCAAA
GAACGCATAAGGAAAAGGCC

Downstream 100 bases:

>100_bases
GTGTTTCGATGAGCATGATCGAGAAACTGGCCGCAGAAATTGGCACCTTCAACCTGTCACCGGGACTGCGCGGCATTCCG
GTCGGGAACGCGCCGGTCAG

Product: putative 5-oxoprolinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MTQKRDAIAEMRLQIMWNRLISVVEEQALTLVRTAFSTSVREAGDLSAGVFNIAGEMVAQAVTGTPGHVNAMGEAVSHFI
NTIGRDNIFEGDVYITNDPWKGTGHLHDFTVVSPSFHKGSLIGFFACTAHVVDVGGRGFGPDAGEVYEEGIFIPIMKFAE
RGAVNRDLINIVRNNVREADQVVGDLYSLAACNEIGHKRLLEMLAEFDIADIEDLAKFIFDHSYQATVDRIAELPAGIYR
NSMRVDGYGSAIDMVVKLDVRKDEIIADFDGTSPPSPLGINVPLIYTTAYAAYGLKCSLAPEIPNNAASLKPFRIIAPEN
CILNAQRPAPVAVRHVLGHFVPDTVLGAVHKMLPDTVPAEGAGALWNIHLSARPSQGRAANGFDLHRTEILMFNSGGSGA
RPTLDGLNATAFPSGVHSMSVEATEHVGPVIVWRKELRNGSGGEGRQRGGLGQVVEIAPTDGHEFYFNAMFDRVENAARG
REGGENGASGRAYLNDGTALNAKGRQFVPEGKRLVIELPGGGGYGKPDDRPHEAVERDRLDQYVVSK

Sequences:

>Translated_547_residues
MTQKRDAIAEMRLQIMWNRLISVVEEQALTLVRTAFSTSVREAGDLSAGVFNIAGEMVAQAVTGTPGHVNAMGEAVSHFI
NTIGRDNIFEGDVYITNDPWKGTGHLHDFTVVSPSFHKGSLIGFFACTAHVVDVGGRGFGPDAGEVYEEGIFIPIMKFAE
RGAVNRDLINIVRNNVREADQVVGDLYSLAACNEIGHKRLLEMLAEFDIADIEDLAKFIFDHSYQATVDRIAELPAGIYR
NSMRVDGYGSAIDMVVKLDVRKDEIIADFDGTSPPSPLGINVPLIYTTAYAAYGLKCSLAPEIPNNAASLKPFRIIAPEN
CILNAQRPAPVAVRHVLGHFVPDTVLGAVHKMLPDTVPAEGAGALWNIHLSARPSQGRAANGFDLHRTEILMFNSGGSGA
RPTLDGLNATAFPSGVHSMSVEATEHVGPVIVWRKELRNGSGGEGRQRGGLGQVVEIAPTDGHEFYFNAMFDRVENAARG
REGGENGASGRAYLNDGTALNAKGRQFVPEGKRLVIELPGGGGYGKPDDRPHEAVERDRLDQYVVSK
>Mature_546_residues
TQKRDAIAEMRLQIMWNRLISVVEEQALTLVRTAFSTSVREAGDLSAGVFNIAGEMVAQAVTGTPGHVNAMGEAVSHFIN
TIGRDNIFEGDVYITNDPWKGTGHLHDFTVVSPSFHKGSLIGFFACTAHVVDVGGRGFGPDAGEVYEEGIFIPIMKFAER
GAVNRDLINIVRNNVREADQVVGDLYSLAACNEIGHKRLLEMLAEFDIADIEDLAKFIFDHSYQATVDRIAELPAGIYRN
SMRVDGYGSAIDMVVKLDVRKDEIIADFDGTSPPSPLGINVPLIYTTAYAAYGLKCSLAPEIPNNAASLKPFRIIAPENC
ILNAQRPAPVAVRHVLGHFVPDTVLGAVHKMLPDTVPAEGAGALWNIHLSARPSQGRAANGFDLHRTEILMFNSGGSGAR
PTLDGLNATAFPSGVHSMSVEATEHVGPVIVWRKELRNGSGGEGRQRGGLGQVVEIAPTDGHEFYFNAMFDRVENAARGR
EGGENGASGRAYLNDGTALNAKGRQFVPEGKRLVIELPGGGGYGKPDDRPHEAVERDRLDQYVVSK

Specific function: Unknown

COG id: COG0146

COG function: function code EQ; N-methylhydantoinase B/acetone carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=554, Percent_Identity=29.2418772563177, Blast_Score=139, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI133901900, Length=558, Percent_Identity=28.673835125448, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI133901902, Length=552, Percent_Identity=27.8985507246377, Blast_Score=152, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6322634, Length=559, Percent_Identity=27.7280858676207, Blast_Score=155, Evalue=2e-38,
Organism=Drosophila melanogaster, GI45550492, Length=567, Percent_Identity=26.1022927689594, Blast_Score=125, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003692 [H]

Pfam domain/function: PF02538 Hydantoinase_B [H]

EC number: NA

Molecular weight: Translated: 59065; Mature: 58934

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKRDAIAEMRLQIMWNRLISVVEEQALTLVRTAFSTSVREAGDLSAGVFNIAGEMVAQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AVTGTPGHVNAMGEAVSHFINTIGRDNIFEGDVYITNDPWKGTGHLHDFTVVSPSFHKGS
HHCCCCCCHHHHHHHHHHHHHHCCCCCEECCCEEEECCCCCCCCCCEEEEEECCCCCCCC
LIGFFACTAHVVDVGGRGFGPDAGEVYEEGIFIPIMKFAERGAVNRDLINIVRNNVREAD
CHHHHHHHHHHHCCCCCCCCCCHHHHHHCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QVVGDLYSLAACNEIGHKRLLEMLAEFDIADIEDLAKFIFDHSYQATVDRIAELPAGIYR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHH
NSMRVDGYGSAIDMVVKLDVRKDEIIADFDGTSPPSPLGINVPLIYTTAYAAYGLKCSLA
CCEEECCCCCCEEEEEEEECCCCCEEEECCCCCCCCCCCCCCCEEEEHHHHHHCCEEEEC
PEIPNNAASLKPFRIIAPENCILNAQRPAPVAVRHVLGHFVPDTVLGAVHKMLPDTVPAE
CCCCCCCCCCCCEEEECCCCEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCC
GAGALWNIHLSARPSQGRAANGFDLHRTEILMFNSGGSGARPTLDGLNATAFPSGVHSMS
CCCCEEEEEEECCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEE
VEATEHVGPVIVWRKELRNGSGGEGRQRGGLGQVVEIAPTDGHEFYFNAMFDRVENAARG
CCHHHCCCCEEEEHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCC
REGGENGASGRAYLNDGTALNAKGRQFVPEGKRLVIELPGGGGYGKPDDRPHEAVERDRL
CCCCCCCCCCCEEECCCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHH
DQYVVSK
HHHHCCC
>Mature Secondary Structure 
TQKRDAIAEMRLQIMWNRLISVVEEQALTLVRTAFSTSVREAGDLSAGVFNIAGEMVAQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AVTGTPGHVNAMGEAVSHFINTIGRDNIFEGDVYITNDPWKGTGHLHDFTVVSPSFHKGS
HHCCCCCCHHHHHHHHHHHHHHCCCCCEECCCEEEECCCCCCCCCCEEEEEECCCCCCCC
LIGFFACTAHVVDVGGRGFGPDAGEVYEEGIFIPIMKFAERGAVNRDLINIVRNNVREAD
CHHHHHHHHHHHCCCCCCCCCCHHHHHHCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QVVGDLYSLAACNEIGHKRLLEMLAEFDIADIEDLAKFIFDHSYQATVDRIAELPAGIYR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHH
NSMRVDGYGSAIDMVVKLDVRKDEIIADFDGTSPPSPLGINVPLIYTTAYAAYGLKCSLA
CCEEECCCCCCEEEEEEEECCCCCEEEECCCCCCCCCCCCCCCEEEEHHHHHHCCEEEEC
PEIPNNAASLKPFRIIAPENCILNAQRPAPVAVRHVLGHFVPDTVLGAVHKMLPDTVPAE
CCCCCCCCCCCCEEEECCCCEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCC
GAGALWNIHLSARPSQGRAANGFDLHRTEILMFNSGGSGARPTLDGLNATAFPSGVHSMS
CCCCEEEEEEECCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEE
VEATEHVGPVIVWRKELRNGSGGEGRQRGGLGQVVEIAPTDGHEFYFNAMFDRVENAARG
CCHHHCCCCEEEEHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCC
REGGENGASGRAYLNDGTALNAKGRQFVPEGKRLVIELPGGGGYGKPDDRPHEAVERDRL
CCCCCCCCCCCEEECCCCEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHH
DQYVVSK
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]