Click here to switch to the map view.

The map label for this gene is betA [C]

Identifier: 190895126

GI number: 190895126

Start: 854641

End: 856290

Strand: Reverse

Name: betA [C]

Synonym: RHECIAT_PC0000796

Alternate gene names: 190895126

Gene position: 856290-854641 (Counterclockwise)

Preceding gene: 190895127

Following gene: 190895122

Centisome position: 78.45

GC content: 58.73

Gene sequence:

>1650_bases
ATGTTGCTTCCCCCGTTTGGCTCTGCGCGCTACGGAATCAAGCCGCATTCTGGCAAGCACCATCGCTACGACTATATTGT
CGTCGGCGGCGGGTCGACCGGCTGTGTGATCGCCTCGCGATTGTCCGAGGATGAAAATCTCCGAGTGGCTCTCCTAGAGG
AGGGGCCTACCGATTCTAGCCCATACATCCACATTCCAGGCGCCTACTACAAGACTGCTCAGGGAAGCCTCTTGAAGCGT
TTCGCCTGGGAGGCTGGTCCGGAGCTTGCGCGTAACGAGCAGCAGACGATGGTACAGGCGCGCGTGCTCGGCGGCGGTAG
TTCGGTCAACGCGATGATCTATATTCGCGGTGTTCCCTCGGACTACCAGCAGTGGGTGCAATTGGGCGCTGCGGGATGGG
CCTATGAGGACGTGCTTCCATATTTCAGGCGTTCCGAGGACAATAACCGTTTTTGCAATGATGCACACGGCGTCGGAGGT
CCGCTCGGCGTCTCCGACATCGATCACGTCCATCCCTTGACGCGCGGTTGGCTACAGGCATGCCAGCAGGCGGGTCTTCC
CTATAACCCGGATTTCAACTCCGGCAGTCAGGCGGGGTGCGGGCTCTATCAGATTACCGCAAGGGACGGTAAACGCAGCA
GTGCTGCCGTCGCCTATATCAAGCCAGCGAAGGGACGACCGAACTTGCAGGTCGTCACTCGCACCACTGTCACTCGGCTG
ATCATCGAAAACGGCAGGGCTGTCGGTGTCGAATACATCCGCAATGGTGAGAAGCATGTGCTGCGTGCGGAGCGCGAAGT
CATCGTGTCGGCGGGCGCGATCGCCACGCCGAAACTCCTGATGCTTTCAGGCATCGGACCAGCCACCGAGTTGAAGCGGC
ACGGGATCACCGTGCATGCAGATCTTCCAGGTGTCGGTAAGAACCTGCAGGACCACGTGGAAATATCACTGATCTATCAA
CTGAGTGGTCCCTACAGTTACGACAAATACAAGAAGATGCATTGGAAGGCGGCCGCCGGTTTGAATTACGCGCTTTTCAA
GGGCGGGCCTGCATCATCAAACCTCATCGAGGGCGGTGCGTTTTGGTGGGGCAATAAGAGCGAACATGTCCCCGACATCC
AGTTTTTCATGGTGGTCGGCGCGGGCATCGAGGAAGGTGTCGATGCCGTACCGGGCGGCAATGGTTGCACGATCAACCTC
GGTCAGATCCGGCCGAGGTCGCGAGGCGAAGTCACCTTGCAAAGCGGCGATTTCAACGCCGATGCCCGCGTTGCGCCCAA
TTACTTCTCTGATCCGTACGACTTGGAGGCAATCACCGAGGGTACAATGGTGGCGATGGATATCATGTCAAAACCGGCGC
TCTCGAAATATCTCCAGTCACGATATGTGCCGGCCCCGAGCGTCAGCACGCGCGATGACATCCGCGCGTTCTGTCAGAGA
GCCGCGCACGCAGCACTGCATCCGTCGGGGACTTGCCGGATGGGTATCGACGAGATGGCTGTGGTCGACCCGCAACTTCG
CGTCAGTGGGATCGAAGGCCTTCGCGTCGCCGACGCATCAGTTATGCCGACATTGATTTCTGGCAATCCAAATGCCGTCT
GCATCATGATCGGGGAACGGGCGGCCGACTTTCTGCGCCTCACACACTAG

Upstream 100 bases:

>100_bases
TTGCCGATGCCTCAGTTCTTCCAACATCGGCGGCAGTTAACCCGGCCCTGACCATCGCTGCCCTCGCGATCAAGGCGGGT
GCTTCGATACGAGGTGTGTG

Downstream 100 bases:

>100_bases
AGCGACAGAGACAACTTGATCGAGCGGGCGATGTTGGCAACGACATCGCCCGCTCTCGTTTATCGCGAAGGAGTCCGTTC
CACCAAAAGGTCCAAGCCAC

Product: putative dehydrogenase

Products: NA

Alternate protein names: SDH [H]

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MLLPPFGSARYGIKPHSGKHHRYDYIVVGGGSTGCVIASRLSEDENLRVALLEEGPTDSSPYIHIPGAYYKTAQGSLLKR
FAWEAGPELARNEQQTMVQARVLGGGSSVNAMIYIRGVPSDYQQWVQLGAAGWAYEDVLPYFRRSEDNNRFCNDAHGVGG
PLGVSDIDHVHPLTRGWLQACQQAGLPYNPDFNSGSQAGCGLYQITARDGKRSSAAVAYIKPAKGRPNLQVVTRTTVTRL
IIENGRAVGVEYIRNGEKHVLRAEREVIVSAGAIATPKLLMLSGIGPATELKRHGITVHADLPGVGKNLQDHVEISLIYQ
LSGPYSYDKYKKMHWKAAAGLNYALFKGGPASSNLIEGGAFWWGNKSEHVPDIQFFMVVGAGIEEGVDAVPGGNGCTINL
GQIRPRSRGEVTLQSGDFNADARVAPNYFSDPYDLEAITEGTMVAMDIMSKPALSKYLQSRYVPAPSVSTRDDIRAFCQR
AAHAALHPSGTCRMGIDEMAVVDPQLRVSGIEGLRVADASVMPTLISGNPNAVCIMIGERAADFLRLTH

Sequences:

>Translated_549_residues
MLLPPFGSARYGIKPHSGKHHRYDYIVVGGGSTGCVIASRLSEDENLRVALLEEGPTDSSPYIHIPGAYYKTAQGSLLKR
FAWEAGPELARNEQQTMVQARVLGGGSSVNAMIYIRGVPSDYQQWVQLGAAGWAYEDVLPYFRRSEDNNRFCNDAHGVGG
PLGVSDIDHVHPLTRGWLQACQQAGLPYNPDFNSGSQAGCGLYQITARDGKRSSAAVAYIKPAKGRPNLQVVTRTTVTRL
IIENGRAVGVEYIRNGEKHVLRAEREVIVSAGAIATPKLLMLSGIGPATELKRHGITVHADLPGVGKNLQDHVEISLIYQ
LSGPYSYDKYKKMHWKAAAGLNYALFKGGPASSNLIEGGAFWWGNKSEHVPDIQFFMVVGAGIEEGVDAVPGGNGCTINL
GQIRPRSRGEVTLQSGDFNADARVAPNYFSDPYDLEAITEGTMVAMDIMSKPALSKYLQSRYVPAPSVSTRDDIRAFCQR
AAHAALHPSGTCRMGIDEMAVVDPQLRVSGIEGLRVADASVMPTLISGNPNAVCIMIGERAADFLRLTH
>Mature_549_residues
MLLPPFGSARYGIKPHSGKHHRYDYIVVGGGSTGCVIASRLSEDENLRVALLEEGPTDSSPYIHIPGAYYKTAQGSLLKR
FAWEAGPELARNEQQTMVQARVLGGGSSVNAMIYIRGVPSDYQQWVQLGAAGWAYEDVLPYFRRSEDNNRFCNDAHGVGG
PLGVSDIDHVHPLTRGWLQACQQAGLPYNPDFNSGSQAGCGLYQITARDGKRSSAAVAYIKPAKGRPNLQVVTRTTVTRL
IIENGRAVGVEYIRNGEKHVLRAEREVIVSAGAIATPKLLMLSGIGPATELKRHGITVHADLPGVGKNLQDHVEISLIYQ
LSGPYSYDKYKKMHWKAAAGLNYALFKGGPASSNLIEGGAFWWGNKSEHVPDIQFFMVVGAGIEEGVDAVPGGNGCTINL
GQIRPRSRGEVTLQSGDFNADARVAPNYFSDPYDLEAITEGTMVAMDIMSKPALSKYLQSRYVPAPSVSTRDDIRAFCQR
AAHAALHPSGTCRMGIDEMAVVDPQLRVSGIEGLRVADASVMPTLISGNPNAVCIMIGERAADFLRLTH

Specific function: Can Catalyze The Oxidation Of Choline To Betaine Aldehyde And Betaine Aldehyde To Glycine Betaine At The Same Rate. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=537, Percent_Identity=40.5959031657356, Blast_Score=364, Evalue=1e-100,
Organism=Escherichia coli, GI1786503, Length=537, Percent_Identity=37.8026070763501, Blast_Score=323, Evalue=2e-89,
Organism=Caenorhabditis elegans, GI17532301, Length=558, Percent_Identity=36.3799283154122, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24642048, Length=569, Percent_Identity=35.8523725834798, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI24642042, Length=570, Percent_Identity=37.5438596491228, Blast_Score=314, Evalue=1e-85,
Organism=Drosophila melanogaster, GI45549471, Length=568, Percent_Identity=36.0915492957746, Blast_Score=311, Evalue=1e-84,
Organism=Drosophila melanogaster, GI45551458, Length=568, Percent_Identity=36.0915492957746, Blast_Score=310, Evalue=2e-84,
Organism=Drosophila melanogaster, GI24642055, Length=580, Percent_Identity=35.8620689655172, Blast_Score=298, Evalue=9e-81,
Organism=Drosophila melanogaster, GI24642059, Length=570, Percent_Identity=34.3859649122807, Blast_Score=291, Evalue=1e-78,
Organism=Drosophila melanogaster, GI24650267, Length=573, Percent_Identity=33.3333333333333, Blast_Score=276, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24642039, Length=573, Percent_Identity=33.8568935427574, Blast_Score=266, Evalue=4e-71,
Organism=Drosophila melanogaster, GI17137792, Length=565, Percent_Identity=32.9203539823009, Blast_Score=262, Evalue=5e-70,
Organism=Drosophila melanogaster, GI18859993, Length=573, Percent_Identity=32.2862129144852, Blast_Score=258, Evalue=5e-69,
Organism=Drosophila melanogaster, GI18859995, Length=567, Percent_Identity=33.8624338624339, Blast_Score=257, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24642037, Length=578, Percent_Identity=32.0069204152249, Blast_Score=248, Evalue=6e-66,
Organism=Drosophila melanogaster, GI24642035, Length=568, Percent_Identity=32.0422535211268, Blast_Score=248, Evalue=9e-66,
Organism=Drosophila melanogaster, GI24642051, Length=572, Percent_Identity=31.2937062937063, Blast_Score=238, Evalue=9e-63,
Organism=Drosophila melanogaster, GI24642057, Length=583, Percent_Identity=28.6449399656947, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24645930, Length=575, Percent_Identity=25.7391304347826, Blast_Score=127, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.32 [H]

Molecular weight: Translated: 59390; Mature: 59390

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS00623 GMC_OXRED_1 ; PS00624 GMC_OXRED_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLPPFGSARYGIKPHSGKHHRYDYIVVGGGSTGCVIASRLSEDENLRVALLEEGPTDSS
CCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCCCCCEEEEEEECCCCCCC
PYIHIPGAYYKTAQGSLLKRFAWEAGPELARNEQQTMVQARVLGGGSSVNAMIYIRGVPS
CEEEECCCCEECCCHHHHHHHHHHCCHHHHCCHHHHEEEHEEECCCCCEEEEEEEECCCH
DYQQWVQLGAAGWAYEDVLPYFRRSEDNNRFCNDAHGVGGPLGVSDIDHVHPLTRGWLQA
HHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
CQQAGLPYNPDFNSGSQAGCGLYQITARDGKRSSAAVAYIKPAKGRPNLQVVTRTTVTRL
HHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCEEEEEHHHEEEH
IIENGRAVGVEYIRNGEKHVLRAEREVIVSAGAIATPKLLMLSGIGPATELKRHGITVHA
HHHCCCEEEHHHHHCCCHHHHHHHHHEEEECCCCCCCCEEEEECCCCHHHHHHCCEEEEE
DLPGVGKNLQDHVEISLIYQLSGPYSYDKYKKMHWKAAAGLNYALFKGGPASSNLIEGGA
CCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCEECCCE
FWWGNKSEHVPDIQFFMVVGAGIEEGVDAVPGGNGCTINLGQIRPRSRGEVTLQSGDFNA
EEECCCCCCCCCEEEEEEECCCHHHCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCC
DARVAPNYFSDPYDLEAITEGTMVAMDIMSKPALSKYLQSRYVPAPSVSTRDDIRAFCQR
CCEECCCCCCCCCCCHHHCCCCEEEEHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
AAHAALHPSGTCRMGIDEMAVVDPQLRVSGIEGLRVADASVMPTLISGNPNAVCIMIGER
HHHHHCCCCCCEEECCCHHEEECCCEEEECCCCEEEECCCCCCEEECCCCCEEEEEECCC
AADFLRLTH
CCCHHEECC
>Mature Secondary Structure
MLLPPFGSARYGIKPHSGKHHRYDYIVVGGGSTGCVIASRLSEDENLRVALLEEGPTDSS
CCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCCCCCEEEEEEECCCCCCC
PYIHIPGAYYKTAQGSLLKRFAWEAGPELARNEQQTMVQARVLGGGSSVNAMIYIRGVPS
CEEEECCCCEECCCHHHHHHHHHHCCHHHHCCHHHHEEEHEEECCCCCEEEEEEEECCCH
DYQQWVQLGAAGWAYEDVLPYFRRSEDNNRFCNDAHGVGGPLGVSDIDHVHPLTRGWLQA
HHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
CQQAGLPYNPDFNSGSQAGCGLYQITARDGKRSSAAVAYIKPAKGRPNLQVVTRTTVTRL
HHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCEEEEEHHHEEEH
IIENGRAVGVEYIRNGEKHVLRAEREVIVSAGAIATPKLLMLSGIGPATELKRHGITVHA
HHHCCCEEEHHHHHCCCHHHHHHHHHEEEECCCCCCCCEEEEECCCCHHHHHHCCEEEEE
DLPGVGKNLQDHVEISLIYQLSGPYSYDKYKKMHWKAAAGLNYALFKGGPASSNLIEGGA
CCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCEECCCE
FWWGNKSEHVPDIQFFMVVGAGIEEGVDAVPGGNGCTINLGQIRPRSRGEVTLQSGDFNA
EEECCCCCCCCCEEEEEEECCCHHHCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCC
DARVAPNYFSDPYDLEAITEGTMVAMDIMSKPALSKYLQSRYVPAPSVSTRDDIRAFCQR
CCEECCCCCCCCCCCHHHCCCCEEEEHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
AAHAALHPSGTCRMGIDEMAVVDPQLRVSGIEGLRVADASVMPTLISGNPNAVCIMIGER
HHHHHCCCCCCEEECCCHHEEECCCEEEECCCCEEEECCCCCCEEECCCCCEEEEEECCC
AADFLRLTH
CCCHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9023923 [H]