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The map label for this gene is betA [C]

Identifier: 190895127

GI number: 190895127

Start: 856290

End: 857786

Strand: Reverse

Name: betA [C]

Synonym: RHECIAT_PC0000797

Alternate gene names: 190895127

Gene position: 857786-856290 (Counterclockwise)

Preceding gene: 190895128

Following gene: 190895126

Centisome position: 78.59

GC content: 58.92

Gene sequence:

>1497_bases
ATGCAGCAGACGGCGGATGTGGTAATTATAGGCTCAGGCATCGGAGGAAGTTCGCTTGCCTACAGCCTTGCCGAGAGCGG
CCTCAAGGTCATCATCCTAGAGCGCGGCGGGTACCTCAGAGACAGCGTGGAAGCTCGCGACGACGTCGCGATTTTCCAAC
GGGGCTTCTATCGGCCAGCGGAAGAGTGGCTTGGAACCGACGGTCAAAGCTTCCTTGCCAACAACTACTACTATGTTGGC
GGAAATTCGAAATTCTTCGGCGCTGTGATGTACCGGTATCGAAAGGAAGATTTCGAAGCGCGTCCACACCTCGACGGAAA
TTCGCCGGGGTGGCCATGCACATATGAAGAGCTGGAGCCGTGGTATGAGCGGGCTGAGAAGGTGTTCCAGGTACGTGGCG
CGCTCGGTCAGGATCCGACGGAGCCTTTCCATAGCAAACCCTACACCCATCCTGCCGTTCCCGACGAGGCGCCGATTGCG
TCGGTCCGCGACCGGCTGAAGCGGGCAGGTGTCCATCCGGCGAGCCTGCCGCTGGCGATTGACATCGAGGCTTGGCTTCA
CCGCGCAAAGACGGGCTGGGATGCGTTCCCGAACACAGGTGTCGGCAAGATCGATGCCGAGGTCGGCCCGTTGACGGAGG
CGCTGCGTCATCCAAACGTTACCCTCATGACCGGTGCTAACGTGTCCCGCCTGGAAACGGACGAGACCGGCACCCGCGTG
ACTGCTGCGGTCTTCGTCAAAGACGGGTTCGAGCAGCGGATCTCTGCCGGCATATTCGCTGTCGCCACCGGCGCGGTTCA
GACTGCAGCACTTCTGCTCCGGTCGGCAAGCAAGGCTCACCCAACGGGCTTGGCCAACAGCTCAGACCAAGTCGGCCGGA
ATTTCATGAACCACAACACATCCGCGATGCTGGTACTCGATTATCGCCGCAATGCCTCGGTCTACCAGAAGACCATTGCC
TTCAACGATTTTTATAACGCCGATAACGACTGCCGGGCGCCGCTCGGAAACGTGCAATTGCTGGGGCACATCACCGGCAA
TATTTTGAAAGCGAATTTCCCAGTGCCCGCACCCTCATGGCTGGTCCGCCTGATCGCGCGACACGCCTATGGGTGGTTCC
TCACCAGCGAAGATCTTCCCAATCCGGAAAGCCGGGTGATGGTCCGCGAGGATCGCATCGTCGTCAACTGGATCCGGTCG
AACATGCGCGCCCACCAGGCGCTCATCAAGAAAACAAAGAATGTCATGCGAAAAGCAGGCTTTCCGGTCGTGCTCACGCA
CACCTTCGGTCGAAAAACAACCTCTCACCAGTGCGGCACCGCTCGGCTCGGGCATGATCCGAAAACCTCGGTTGTCGATC
TAAATTGCCGTGCGCATGACGTCGAAAATCTTTATATTGCCGATGCCTCAGTTCTTCCAACATCGGCGGCAGTTAACCCG
GCCCTGACCATCGCTGCCCTCGCGATCAAGGCGGGTGCTTCGATACGAGGTGTGTGA

Upstream 100 bases:

>100_bases
ACGTCACTCAATCGCGCTCTGAAGCATCGCTCGCCGTTGATGCCTCGAAGATCGTCCTGTTCGACGCCCAGACCGAAGCC
AGAATTGATTGAGGTATGCC

Downstream 100 bases:

>100_bases
TGTTGCTTCCCCCGTTTGGCTCTGCGCGCTACGGAATCAAGCCGCATTCTGGCAAGCACCATCGCTACGACTATATTGTC
GTCGGCGGCGGGTCGACCGG

Product: putative dehydrogenase

Products: Betaine Aldehyde; Reduced Acceptor. [C]

Alternate protein names: FAD Dependent Oxidoreductase; Choline Dehydrogenase; Oxidoreductase; Gluconate 2-Dehydrogenase; GMC Oxidoreductase; Dehydrogenase; Flavoprotein Related Choline Dehydrogenase; Dehydrogenase Subunit-Like Protein; Gluconate Dehydrogenase; Glucose Dehydrogenase; 2-Keto-Gluconate Dehydrogenase; GMC Oxidoreductase Family Protein; GMC Oxidoreductase Family; Dehydrogenase Subunit; Oxidoreductase Protein; GMC Family Oxidoreductase; Gluconate 2-Dehydrogenase Flavoprotein; Glucose-Methanol-Choline Family Oxidoreductase; Dehydrogenase Protein; Glucose Dehydrogenase Subunit Alpha; Oxidoreductase-Like Protein; Dehydrogenase Large Subunit Protein; Dehydrogenase-Like Protein; L-Sorbose Dehydrogenase; FAD-Dependent Pyridine Nucleotide-Disulfide Oxidoreductase; Oxidoreductase GMC Family; Sugar-Alcohol Dehydrogenase; Glucase Dehydrogenase Subunit Alpha; Transmembrane Dehydrogenase Protein; Dehydrogenase Subunit I; Choline Dehydrogenase-Like Flavoprotein; 2-Keto-Gluconate Dehydrogenase Subunit; N-Terminal Membrane-Anchored Dehydrogenase; Gluconate Dehydrogenase Subunit; Capsular Polysaccharide Biosynthesis Oxidoreductase; Fad Dependent Oxidoreductase; Gluconate 2-Dehydrogenase Alpha Chain; Dehydrogenase Transmembrane Protein

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MQQTADVVIIGSGIGGSSLAYSLAESGLKVIILERGGYLRDSVEARDDVAIFQRGFYRPAEEWLGTDGQSFLANNYYYVG
GNSKFFGAVMYRYRKEDFEARPHLDGNSPGWPCTYEELEPWYERAEKVFQVRGALGQDPTEPFHSKPYTHPAVPDEAPIA
SVRDRLKRAGVHPASLPLAIDIEAWLHRAKTGWDAFPNTGVGKIDAEVGPLTEALRHPNVTLMTGANVSRLETDETGTRV
TAAVFVKDGFEQRISAGIFAVATGAVQTAALLLRSASKAHPTGLANSSDQVGRNFMNHNTSAMLVLDYRRNASVYQKTIA
FNDFYNADNDCRAPLGNVQLLGHITGNILKANFPVPAPSWLVRLIARHAYGWFLTSEDLPNPESRVMVREDRIVVNWIRS
NMRAHQALIKKTKNVMRKAGFPVVLTHTFGRKTTSHQCGTARLGHDPKTSVVDLNCRAHDVENLYIADASVLPTSAAVNP
ALTIAALAIKAGASIRGV

Sequences:

>Translated_498_residues
MQQTADVVIIGSGIGGSSLAYSLAESGLKVIILERGGYLRDSVEARDDVAIFQRGFYRPAEEWLGTDGQSFLANNYYYVG
GNSKFFGAVMYRYRKEDFEARPHLDGNSPGWPCTYEELEPWYERAEKVFQVRGALGQDPTEPFHSKPYTHPAVPDEAPIA
SVRDRLKRAGVHPASLPLAIDIEAWLHRAKTGWDAFPNTGVGKIDAEVGPLTEALRHPNVTLMTGANVSRLETDETGTRV
TAAVFVKDGFEQRISAGIFAVATGAVQTAALLLRSASKAHPTGLANSSDQVGRNFMNHNTSAMLVLDYRRNASVYQKTIA
FNDFYNADNDCRAPLGNVQLLGHITGNILKANFPVPAPSWLVRLIARHAYGWFLTSEDLPNPESRVMVREDRIVVNWIRS
NMRAHQALIKKTKNVMRKAGFPVVLTHTFGRKTTSHQCGTARLGHDPKTSVVDLNCRAHDVENLYIADASVLPTSAAVNP
ALTIAALAIKAGASIRGV
>Mature_498_residues
MQQTADVVIIGSGIGGSSLAYSLAESGLKVIILERGGYLRDSVEARDDVAIFQRGFYRPAEEWLGTDGQSFLANNYYYVG
GNSKFFGAVMYRYRKEDFEARPHLDGNSPGWPCTYEELEPWYERAEKVFQVRGALGQDPTEPFHSKPYTHPAVPDEAPIA
SVRDRLKRAGVHPASLPLAIDIEAWLHRAKTGWDAFPNTGVGKIDAEVGPLTEALRHPNVTLMTGANVSRLETDETGTRV
TAAVFVKDGFEQRISAGIFAVATGAVQTAALLLRSASKAHPTGLANSSDQVGRNFMNHNTSAMLVLDYRRNASVYQKTIA
FNDFYNADNDCRAPLGNVQLLGHITGNILKANFPVPAPSWLVRLIARHAYGWFLTSEDLPNPESRVMVREDRIVVNWIRS
NMRAHQALIKKTKNVMRKAGFPVVLTHTFGRKTTSHQCGTARLGHDPKTSVVDLNCRAHDVENLYIADASVLPTSAAVNP
ALTIAALAIKAGASIRGV

Specific function: Can Catalyze The Oxidation Of Choline To Betaine Aldehyde And Betaine Aldehyde To Glycine Betaine At The Same Rate. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.99.1 [C]

Molecular weight: Translated: 54568; Mature: 54568

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS00221 MIP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQTADVVIIGSGIGGSSLAYSLAESGLKVIILERGGYLRDSVEARDDVAIFQRGFYRPA
CCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCH
EEWLGTDGQSFLANNYYYVGGNSKFFGAVMYRYRKEDFEARPHLDGNSPGWPCTYEELEP
HHHCCCCCCHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
WYERAEKVFQVRGALGQDPTEPFHSKPYTHPAVPDEAPIASVRDRLKRAGVHPASLPLAI
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEE
DIEAWLHRAKTGWDAFPNTGVGKIDAEVGPLTEALRHPNVTLMTGANVSRLETDETGTRV
EHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHCCCEEEEECCCCCEEECCCCCCEE
TAAVFVKDGFEQRISAGIFAVATGAVQTAALLLRSASKAHPTGLANSSDQVGRNFMNHNT
EEEEEECCCHHHHHHCCHHEEHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCC
SAMLVLDYRRNASVYQKTIAFNDFYNADNDCRAPLGNVQLLGHITGNILKANFPVPAPSW
CEEEEEEECCCCHHHHHHHEEHHCCCCCCCCCCCCCCEEEEEEECCCEEEECCCCCCHHH
LVRLIARHAYGWFLTSEDLPNPESRVMVREDRIVVNWIRSNMRAHQALIKKTKNVMRKAG
HHHHHHHHHCCEEEECCCCCCCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHCC
FPVVLTHTFGRKTTSHQCGTARLGHDPKTSVVDLNCRAHDVENLYIADASVLPTSAAVNP
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEECCCCCCCCCCCCH
ALTIAALAIKAGASIRGV
HHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQQTADVVIIGSGIGGSSLAYSLAESGLKVIILERGGYLRDSVEARDDVAIFQRGFYRPA
CCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCH
EEWLGTDGQSFLANNYYYVGGNSKFFGAVMYRYRKEDFEARPHLDGNSPGWPCTYEELEP
HHHCCCCCCHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
WYERAEKVFQVRGALGQDPTEPFHSKPYTHPAVPDEAPIASVRDRLKRAGVHPASLPLAI
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEE
DIEAWLHRAKTGWDAFPNTGVGKIDAEVGPLTEALRHPNVTLMTGANVSRLETDETGTRV
EHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHCCCEEEEECCCCCEEECCCCCCEE
TAAVFVKDGFEQRISAGIFAVATGAVQTAALLLRSASKAHPTGLANSSDQVGRNFMNHNT
EEEEEECCCHHHHHHCCHHEEHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCC
SAMLVLDYRRNASVYQKTIAFNDFYNADNDCRAPLGNVQLLGHITGNILKANFPVPAPSW
CEEEEEEECCCCHHHHHHHEEHHCCCCCCCCCCCCCCEEEEEEECCCEEEECCCCCCHHH
LVRLIARHAYGWFLTSEDLPNPESRVMVREDRIVVNWIRSNMRAHQALIKKTKNVMRKAG
HHHHHHHHHCCEEEECCCCCCCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHCC
FPVVLTHTFGRKTTSHQCGTARLGHDPKTSVVDLNCRAHDVENLYIADASVLPTSAAVNP
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEECCCCCCCCCCCCH
ALTIAALAIKAGASIRGV
HHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Coenzyme Q [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 7 {choline}} 1.1 {phenazine}} [C]

Substrates: Choline; Acceptor [C]

Specific reaction: Choline + Acceptor = Betaine Aldehyde + Reduced Acceptor. [C]

General reaction: Redox reaction [C]

Inhibitor: 2-Dimethylaminoethanol; Betaine aldehyde; Monoethanolamine; Semicarbazide [C]

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA