Click here to switch to the map view.

The map label for this gene is lpsB2 [H]

Identifier: 190894686

GI number: 190894686

Start: 375283

End: 377229

Strand: Reverse

Name: lpsB2 [H]

Synonym: RHECIAT_PC0000349

Alternate gene names: 190894686

Gene position: 377229-375283 (Counterclockwise)

Preceding gene: 190894687

Following gene: 190894682

Centisome position: 34.56

GC content: 59.32

Gene sequence:

>1947_bases
GTGCCGATGCAGGCGCTCGTCGCCCCTCTGCTGGCGATGCCGCGTCCTGCCAAACGCGCGCTCGCCTTGCTGGTGGATTC
GAGCTTTTGCGTCCTGACGATCTGGCTGGCTTATTGCTTCCGACTGAACGAATGGACGGTGCTGACCGGCGTGCAGTGGT
TGCCGGTCTTCGTCTCCCTGTGCATGGCCCTTCCTATCTTCATCGTCATGGGCATGTATCGGGCAATCTTCCGCTACGCC
GGCCTTGCCGCTTTCATCGCGGTTTTGAAGGCTATTGCGATCTACGGCGTCGCCTTCATGACGATTTTTACTGCGCTGAG
CGTCCCTGGCGTTCCGAGAACGGTCGGTATTCTTCAGCCTTTCCTGCTGCTGATTGCGATCGGCCTGTCGCGACTGGGCA
TCCGCTATTGGCTCGGCGATACCTATCAGCGTATCCTTCACCAGAATACGCTCGCCAAGGTGCTGATCTACGGGGCAGGG
AATGCCGGCCGACAATTGGCCGGCGCTCTGACGAACAGCGCCGAACTCAATGTCGTCGGTTACCTGGACGATGATCCGCG
TCTTAAGGGCGGCATCATGGGCGGCTTGCCGATCTACGACCCGTCGGATCTTCCGGTGCTCGCCGAAGCTCTTGGCGTGC
ACAACGTGCTTCTTGCTTTGCCATCCGCATCGCGGCAGCGGCGCAATGAAATCCTCGAGCGCATTCGCAAAGCCAGGGTG
AATGTTCGGACATTGCCGGACCTCACGGCGCTTGCTCAGGGCCGTGTCGCCGTCTCCGACATTCGCGAGCTGGAGATCGA
AGATCTGCTGGGCAGGGAAGCGGTGGCGCCGCGGCAGGAATTGCTCGACAAGGCGATGCGCAAAAAGGTGGTGATGGTCA
CGGGCGCTGGCGGTTCCATCGGTGGTGAACTCTGTCGGCAGATTCTGCGCAACGCGCCTTCGAGCCTCATCCTCATCGAT
CAGAACGAGTTCGCGCTTTATAATATCCACGCCGAATTGCTGAAGCTGGCCGAACTTTACAAGCAGGAAAGCCTGCAGAT
CGTTCCGATCCTTTGTTCCGTCCGCGACCAGGACCGCATGGAACATATCATGCAGAGCTGGCGGCCGCAGACGCTCTATC
ATGCCGCCGCTTACAAGCATGTGCCTCTCGTCGAACATAATGCGGTGGAAGGCATCAAGAACAACGTCATGGGGACGCTG
ATCACCGCACGCGCGGCGAATAAATGCGGCGTCTTGAATTTCGTGCTGATCAGTACGGACAAGGCCGTGCGTCCGACGAA
CGTGATGGGCGCCAGCAAGAGGCTGGCGGAGATGGTTCTGCAAGCGCTTGCTGCAGAACCGGCCGTTGACAGAGTGCGCA
CGAATTTCTCCATGGTCCGGTTTGGAAACGTGCTCGGCTCCTCCGGATCCGTCGTGCCGCTGTTCCGGCAGCAGATCAAG
GACGGCGGGCCGGTTACCTTGACGCACCCGAAAATAACCCGCTACTTCATGACCATTTCGGAGGCCTCGCAGCTGGTCAT
TCAGGCGGGCGCGATGGCCGAAGGTGGGGATGTTTTCCTGCTCGACATGGGCGAGCCCGTCCGCATCGCCGATCTCGCCC
GCAAGATGGTGGAGCTTTCGGGATTGGCCGTCCGAGACGAGGATAATCCCGAAGGGGATATCGAGCTTTCCGTGACCGGC
CTGAGACCCGGCGAGAAGCTTTATGAAGAACTGTTGATCGGGGATAATCCTGAAACAACCGAACATCCCAGGATTATGAA
GGCGCGCGAGGATTTCCTGTTCTGGCCGGAGCTTTCGAAGAAACTCAGCTCGCTCAATGCGGCACTGGATCGAAACGATA
TGGTCGCGGCACGTGCGACCTTGGCAGAACTCGTCTCCGGTTATTCCTCAACCGGTGAGGTGTCGGATCTTGCCTTCACC
GGCGCCGAAACCATCACGGCAGCCTGA

Upstream 100 bases:

>100_bases
GAAAATGACAAGAAGGGGATTGTCTGATTGATCCGCGAGACGCTGGGAAGCAATGCCTGAAAATACCCCCACTGAGACGC
CACGCTCAGCATGGTTCTTA

Downstream 100 bases:

>100_bases
AGACGACAATCAGCGACGTTGAGCGCGGGAATTCAGCTTCGCACGACGGGCGCGAAGCGTGTGCTGCCCCGATCCACGCA
AATGAGGGCGACCATATAGG

Product: dTDP-glucose 4,6-dehydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 648; Mature: 647

Protein sequence:

>648_residues
MPMQALVAPLLAMPRPAKRALALLVDSSFCVLTIWLAYCFRLNEWTVLTGVQWLPVFVSLCMALPIFIVMGMYRAIFRYA
GLAAFIAVLKAIAIYGVAFMTIFTALSVPGVPRTVGILQPFLLLIAIGLSRLGIRYWLGDTYQRILHQNTLAKVLIYGAG
NAGRQLAGALTNSAELNVVGYLDDDPRLKGGIMGGLPIYDPSDLPVLAEALGVHNVLLALPSASRQRRNEILERIRKARV
NVRTLPDLTALAQGRVAVSDIRELEIEDLLGREAVAPRQELLDKAMRKKVVMVTGAGGSIGGELCRQILRNAPSSLILID
QNEFALYNIHAELLKLAELYKQESLQIVPILCSVRDQDRMEHIMQSWRPQTLYHAAAYKHVPLVEHNAVEGIKNNVMGTL
ITARAANKCGVLNFVLISTDKAVRPTNVMGASKRLAEMVLQALAAEPAVDRVRTNFSMVRFGNVLGSSGSVVPLFRQQIK
DGGPVTLTHPKITRYFMTISEASQLVIQAGAMAEGGDVFLLDMGEPVRIADLARKMVELSGLAVRDEDNPEGDIELSVTG
LRPGEKLYEELLIGDNPETTEHPRIMKAREDFLFWPELSKKLSSLNAALDRNDMVAARATLAELVSGYSSTGEVSDLAFT
GAETITAA

Sequences:

>Translated_648_residues
MPMQALVAPLLAMPRPAKRALALLVDSSFCVLTIWLAYCFRLNEWTVLTGVQWLPVFVSLCMALPIFIVMGMYRAIFRYA
GLAAFIAVLKAIAIYGVAFMTIFTALSVPGVPRTVGILQPFLLLIAIGLSRLGIRYWLGDTYQRILHQNTLAKVLIYGAG
NAGRQLAGALTNSAELNVVGYLDDDPRLKGGIMGGLPIYDPSDLPVLAEALGVHNVLLALPSASRQRRNEILERIRKARV
NVRTLPDLTALAQGRVAVSDIRELEIEDLLGREAVAPRQELLDKAMRKKVVMVTGAGGSIGGELCRQILRNAPSSLILID
QNEFALYNIHAELLKLAELYKQESLQIVPILCSVRDQDRMEHIMQSWRPQTLYHAAAYKHVPLVEHNAVEGIKNNVMGTL
ITARAANKCGVLNFVLISTDKAVRPTNVMGASKRLAEMVLQALAAEPAVDRVRTNFSMVRFGNVLGSSGSVVPLFRQQIK
DGGPVTLTHPKITRYFMTISEASQLVIQAGAMAEGGDVFLLDMGEPVRIADLARKMVELSGLAVRDEDNPEGDIELSVTG
LRPGEKLYEELLIGDNPETTEHPRIMKAREDFLFWPELSKKLSSLNAALDRNDMVAARATLAELVSGYSSTGEVSDLAFT
GAETITAA
>Mature_647_residues
PMQALVAPLLAMPRPAKRALALLVDSSFCVLTIWLAYCFRLNEWTVLTGVQWLPVFVSLCMALPIFIVMGMYRAIFRYAG
LAAFIAVLKAIAIYGVAFMTIFTALSVPGVPRTVGILQPFLLLIAIGLSRLGIRYWLGDTYQRILHQNTLAKVLIYGAGN
AGRQLAGALTNSAELNVVGYLDDDPRLKGGIMGGLPIYDPSDLPVLAEALGVHNVLLALPSASRQRRNEILERIRKARVN
VRTLPDLTALAQGRVAVSDIRELEIEDLLGREAVAPRQELLDKAMRKKVVMVTGAGGSIGGELCRQILRNAPSSLILIDQ
NEFALYNIHAELLKLAELYKQESLQIVPILCSVRDQDRMEHIMQSWRPQTLYHAAAYKHVPLVEHNAVEGIKNNVMGTLI
TARAANKCGVLNFVLISTDKAVRPTNVMGASKRLAEMVLQALAAEPAVDRVRTNFSMVRFGNVLGSSGSVVPLFRQQIKD
GGPVTLTHPKITRYFMTISEASQLVIQAGAMAEGGDVFLLDMGEPVRIADLARKMVELSGLAVRDEDNPEGDIELSVTGL
RPGEKLYEELLIGDNPETTEHPRIMKAREDFLFWPELSKKLSSLNAALDRNDMVAARATLAELVSGYSSTGEVSDLAFTG
AETITAA

Specific function: Required for the biosynthesis of type 1 capsular polysaccharide [H]

COG id: COG1086

COG function: function code MG; Predicted nucleoside-diphosphate sugar epimerases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polysaccharide synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR003869 [H]

Pfam domain/function: PF02719 Polysacc_synt_2 [H]

EC number: NA

Molecular weight: Translated: 70844; Mature: 70713

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMQALVAPLLAMPRPAKRALALLVDSSFCVLTIWLAYCFRLNEWTVLTGVQWLPVFVSL
CCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHH
CMALPIFIVMGMYRAIFRYAGLAAFIAVLKAIAIYGVAFMTIFTALSVPGVPRTVGILQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
FLLLIAIGLSRLGIRYWLGDTYQRILHQNTLAKVLIYGAGNAGRQLAGALTNSAELNVVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHCCCCEEEEEE
YLDDDPRLKGGIMGGLPIYDPSDLPVLAEALGVHNVLLALPSASRQRRNEILERIRKARV
EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
NVRTLPDLTALAQGRVAVSDIRELEIEDLLGREAVAPRQELLDKAMRKKVVMVTGAGGSI
CCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCEEEEEECCCCCC
GGELCRQILRNAPSSLILIDQNEFALYNIHAELLKLAELYKQESLQIVPILCSVRDQDRM
HHHHHHHHHHCCCCCEEEEECCCEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
EHIMQSWRPQTLYHAAAYKHVPLVEHNAVEGIKNNVMGTLITARAANKCGVLNFVLISTD
HHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECC
KAVRPTNVMGASKRLAEMVLQALAAEPAVDRVRTNFSMVRFGNVLGSSGSVVPLFRQQIK
CCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHCCCCCEEHHHHHHCC
DGGPVTLTHPKITRYFMTISEASQLVIQAGAMAEGGDVFLLDMGEPVRIADLARKMVELS
CCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHC
GLAVRDEDNPEGDIELSVTGLRPGEKLYEELLIGDNPETTEHPRIMKAREDFLFWPELSK
CCEEECCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHCEECHHHHH
KLSSLNAALDRNDMVAARATLAELVSGYSSTGEVSDLAFTGAETITAA
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHEECCCHHHCCC
>Mature Secondary Structure 
PMQALVAPLLAMPRPAKRALALLVDSSFCVLTIWLAYCFRLNEWTVLTGVQWLPVFVSL
CHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHH
CMALPIFIVMGMYRAIFRYAGLAAFIAVLKAIAIYGVAFMTIFTALSVPGVPRTVGILQP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
FLLLIAIGLSRLGIRYWLGDTYQRILHQNTLAKVLIYGAGNAGRQLAGALTNSAELNVVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHCCCCEEEEEE
YLDDDPRLKGGIMGGLPIYDPSDLPVLAEALGVHNVLLALPSASRQRRNEILERIRKARV
EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
NVRTLPDLTALAQGRVAVSDIRELEIEDLLGREAVAPRQELLDKAMRKKVVMVTGAGGSI
CCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCEEEEEECCCCCC
GGELCRQILRNAPSSLILIDQNEFALYNIHAELLKLAELYKQESLQIVPILCSVRDQDRM
HHHHHHHHHHCCCCCEEEEECCCEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
EHIMQSWRPQTLYHAAAYKHVPLVEHNAVEGIKNNVMGTLITARAANKCGVLNFVLISTD
HHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECC
KAVRPTNVMGASKRLAEMVLQALAAEPAVDRVRTNFSMVRFGNVLGSSGSVVPLFRQQIK
CCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHCCCCCEEHHHHHHCC
DGGPVTLTHPKITRYFMTISEASQLVIQAGAMAEGGDVFLLDMGEPVRIADLARKMVELS
CCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHC
GLAVRDEDNPEGDIELSVTGLRPGEKLYEELLIGDNPETTEHPRIMKAREDFLFWPELSK
CCEEECCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHCEECHHHHH
KLSSLNAALDRNDMVAARATLAELVSGYSSTGEVSDLAFTGAETITAA
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHEECCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7961465 [H]