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The map label for this gene is dppA [H]

Identifier: 190894535

GI number: 190894535

Start: 197066

End: 198676

Strand: Reverse

Name: dppA [H]

Synonym: RHECIAT_PC0000197

Alternate gene names: 190894535

Gene position: 198676-197066 (Counterclockwise)

Preceding gene: 190894536

Following gene: 190894534

Centisome position: 18.2

GC content: 63.13

Gene sequence:

>1611_bases
ATGACCATTCCAGAAATCTCGCGGCGCACGCTGATGAAGGGCACCGCCCTGCTGCTTGCCTCGACGGCGCTCGCCCGCCA
GACGCTGGCGCAGACCGCGCCGAGCGGCGGGAGACTGGTCGTTGCGGCCGATTCCGAGCCCAAGAACCTCAACCCTGCCA
TCGTCGCTTCAAACGGCGTCTTTTTCATCGCCAGCAAGGTGATCGAACCCCTCGCCGAAGCCTCGTTCGACGGCAAGGAC
GGGCTTGCGCCGCGGCTTGCCACCTCCTGGGAAGGCTCGGCCGACGGCCTTTCCGTCACCTTCAAGCTGCGCGACGGCGT
CACCTGGCATGACGGCAAGCCGTTCACCTCGGTTGATGTCGCCTTTTCCGCCCTCACCATCTGGAAGCCGCTGCAGAATC
TCGGCCGCCTGGTGTTCGCCAATCTCGAAGCAGTCGATACGCCCGACGACTACACCGCCATCTTCCGCTTCTCCAAGCCG
ACGCCGTTCCAGCTCATCCGCAATGCCCTGCCCGTCGTCACCAGCGTCGTCGCTAAACACATCTTCGACGGCAGCGATAT
CGCCACCAATCCGGCCAACAATACGCTCATCGGCACCGGCCCATTCAAGTTCGGCGAACACAAGCCCGGCGAATACTACC
GGCTGACGCGCAATGAGAATTATTGGGACAAGGACCAGCCGAAGCTCGACGAGATCGTCTTCCGCGTGCTGCCCGACCGC
GCGTCGGCCGGTGCCGCGCTCGAAGCCGACGAAATTCAGCTTGCCGCCTTCTCGGCGGTGCCGCTGGCCGATCTCGATCG
CATCTCCAAGGTCGACGGCATCAAGGTGATCTCGAAAGGTTACGAGGCCTTGACCTACCAGCTCGTCGTCGAGATCAATC
ACCGCCGCAAGGAGCTCGCCGACCTCAGGGTCCGCCAGGCGATCGCGCACGCCATCGACAAGAAATTCGTTGTCGACACG
ATCTTCCTCGGTTATGCCGCCGCCGCCACAGGGCCGGTGCCGAAGAATGCGCCGGAATTCTATACATCCGATGTCGCGAC
CTTTGATTTCAATCCGGCAGCCGCCAACGATATTCTCGACAAGGCGGGGTATGCCAAGGCGTCAGACGGCAACCGCTTCA
CGCTGAAGCTCCGTCCCGCGCCCTATTTCAACGAGACCCGCCAGTTCGGCGATTACCTTCGCCAGGCGCTTGCCGCGATC
GGCATCGATGCCGAGATCGTCAATGCCGATGCGGCCGCGCACCAGAAGGCAGTTTATACCGACCACGATTTCGACCTCGC
CGTCGCCCCGCCGGTCTTCCGCGGCGATCCGGCGATCTCCACCACGATTCTCGTTCAGTCCGGTACGCCTGATGGCGTTC
CCTTCTCCAACCAGGGCGGCTATGCCAGTCTGGAGCTCGACAAGATCATCAAGCAGGCCTCCGAAACCGTCGACACGGCG
GCGCGCACCGATCTCTACCGCAAGTTCCAGCAGCTCGTCGTCGCCGATCTGCCGCTGATCAACGTCGCGGAATGGGGCTT
CATCACCGTCGCCCGCGACACCGTCCTCAACGTCGCGGACAATCCGCGCTGGGCCGTCGCGAACTGGGGCGATACCGCGC
TGCAATCGTGA

Upstream 100 bases:

>100_bases
AAAAATGTCTCGCGGAGCCCGATCATTCGAATTTAATCTCTATCCGAACCGGTGTTTCGGGTCGAATATGGTGGCTGGTT
TCGATCGATCAGGAGGGCTC

Downstream 100 bases:

>100_bases
TAGAGCGATTCCAGCAAAGTGTGCCGCGGTTTTGCGTTCGGAATTGCGTAAAAACAAAGATAGATCGGCGGCAAATCTCC
ACCAGAGGCCCTGTCCGGCG

Product: putative oligopeptide ABC transporter substrate-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 536; Mature: 535

Protein sequence:

>536_residues
MTIPEISRRTLMKGTALLLASTALARQTLAQTAPSGGRLVVAADSEPKNLNPAIVASNGVFFIASKVIEPLAEASFDGKD
GLAPRLATSWEGSADGLSVTFKLRDGVTWHDGKPFTSVDVAFSALTIWKPLQNLGRLVFANLEAVDTPDDYTAIFRFSKP
TPFQLIRNALPVVTSVVAKHIFDGSDIATNPANNTLIGTGPFKFGEHKPGEYYRLTRNENYWDKDQPKLDEIVFRVLPDR
ASAGAALEADEIQLAAFSAVPLADLDRISKVDGIKVISKGYEALTYQLVVEINHRRKELADLRVRQAIAHAIDKKFVVDT
IFLGYAAAATGPVPKNAPEFYTSDVATFDFNPAAANDILDKAGYAKASDGNRFTLKLRPAPYFNETRQFGDYLRQALAAI
GIDAEIVNADAAAHQKAVYTDHDFDLAVAPPVFRGDPAISTTILVQSGTPDGVPFSNQGGYASLELDKIIKQASETVDTA
ARTDLYRKFQQLVVADLPLINVAEWGFITVARDTVLNVADNPRWAVANWGDTALQS

Sequences:

>Translated_536_residues
MTIPEISRRTLMKGTALLLASTALARQTLAQTAPSGGRLVVAADSEPKNLNPAIVASNGVFFIASKVIEPLAEASFDGKD
GLAPRLATSWEGSADGLSVTFKLRDGVTWHDGKPFTSVDVAFSALTIWKPLQNLGRLVFANLEAVDTPDDYTAIFRFSKP
TPFQLIRNALPVVTSVVAKHIFDGSDIATNPANNTLIGTGPFKFGEHKPGEYYRLTRNENYWDKDQPKLDEIVFRVLPDR
ASAGAALEADEIQLAAFSAVPLADLDRISKVDGIKVISKGYEALTYQLVVEINHRRKELADLRVRQAIAHAIDKKFVVDT
IFLGYAAAATGPVPKNAPEFYTSDVATFDFNPAAANDILDKAGYAKASDGNRFTLKLRPAPYFNETRQFGDYLRQALAAI
GIDAEIVNADAAAHQKAVYTDHDFDLAVAPPVFRGDPAISTTILVQSGTPDGVPFSNQGGYASLELDKIIKQASETVDTA
ARTDLYRKFQQLVVADLPLINVAEWGFITVARDTVLNVADNPRWAVANWGDTALQS
>Mature_535_residues
TIPEISRRTLMKGTALLLASTALARQTLAQTAPSGGRLVVAADSEPKNLNPAIVASNGVFFIASKVIEPLAEASFDGKDG
LAPRLATSWEGSADGLSVTFKLRDGVTWHDGKPFTSVDVAFSALTIWKPLQNLGRLVFANLEAVDTPDDYTAIFRFSKPT
PFQLIRNALPVVTSVVAKHIFDGSDIATNPANNTLIGTGPFKFGEHKPGEYYRLTRNENYWDKDQPKLDEIVFRVLPDRA
SAGAALEADEIQLAAFSAVPLADLDRISKVDGIKVISKGYEALTYQLVVEINHRRKELADLRVRQAIAHAIDKKFVVDTI
FLGYAAAATGPVPKNAPEFYTSDVATFDFNPAAANDILDKAGYAKASDGNRFTLKLRPAPYFNETRQFGDYLRQALAAIG
IDAEIVNADAAAHQKAVYTDHDFDLAVAPPVFRGDPAISTTILVQSGTPDGVPFSNQGGYASLELDKIIKQASETVDTAA
RTDLYRKFQQLVVADLPLINVAEWGFITVARDTVLNVADNPRWAVANWGDTALQS

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=541, Percent_Identity=24.9537892791128, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1787052, Length=493, Percent_Identity=24.5436105476673, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1789887, Length=458, Percent_Identity=26.6375545851528, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787762, Length=487, Percent_Identity=24.2299794661191, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1787551, Length=476, Percent_Identity=23.3193277310924, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI87081878, Length=533, Percent_Identity=24.015009380863, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789397, Length=497, Percent_Identity=23.5412474849095, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 58139; Mature: 58008

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIPEISRRTLMKGTALLLASTALARQTLAQTAPSGGRLVVAADSEPKNLNPAIVASNGV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEECCCE
FFIASKVIEPLAEASFDGKDGLAPRLATSWEGSADGLSVTFKLRDGVTWHDGKPFTSVDV
EEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCEEECCCCCCCHHHH
AFSALTIWKPLQNLGRLVFANLEAVDTPDDYTAIFRFSKPTPFQLIRNALPVVTSVVAKH
HHHHHHHHHHHHHHHHEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
IFDGSDIATNPANNTLIGTGPFKFGEHKPGEYYRLTRNENYWDKDQPKLDEIVFRVLPDR
HCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCC
ASAGAALEADEIQLAAFSAVPLADLDRISKVDGIKVISKGYEALTYQLVVEINHRRKELA
CCCCCEEECCCEEEEEECCCCHHHHHHHHHHCCHHHHHCCHHHEEEEEEEEECHHHHHHH
DLRVRQAIAHAIDKKFVVDTIFLGYAAAATGPVPKNAPEFYTSDVATFDFNPAAANDILD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCEEEEECCCHHHHHHHH
KAGYAKASDGNRFTLKLRPAPYFNETRQFGDYLRQALAAIGIDAEIVNADAAAHQKAVYT
HCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHCCEEEC
DHDFDLAVAPPVFRGDPAISTTILVQSGTPDGVPFSNQGGYASLELDKIIKQASETVDTA
CCCCCEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHH
ARTDLYRKFQQLVVADLPLINVAEWGFITVARDTVLNVADNPRWAVANWGDTALQS
HHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCEEECCCCCCEEEECCCHHHCCC
>Mature Secondary Structure 
TIPEISRRTLMKGTALLLASTALARQTLAQTAPSGGRLVVAADSEPKNLNPAIVASNGV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEECCCE
FFIASKVIEPLAEASFDGKDGLAPRLATSWEGSADGLSVTFKLRDGVTWHDGKPFTSVDV
EEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCEEECCCCCCCHHHH
AFSALTIWKPLQNLGRLVFANLEAVDTPDDYTAIFRFSKPTPFQLIRNALPVVTSVVAKH
HHHHHHHHHHHHHHHHEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
IFDGSDIATNPANNTLIGTGPFKFGEHKPGEYYRLTRNENYWDKDQPKLDEIVFRVLPDR
HCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCC
ASAGAALEADEIQLAAFSAVPLADLDRISKVDGIKVISKGYEALTYQLVVEINHRRKELA
CCCCCEEECCCEEEEEECCCCHHHHHHHHHHCCHHHHHCCHHHEEEEEEEEECHHHHHHH
DLRVRQAIAHAIDKKFVVDTIFLGYAAAATGPVPKNAPEFYTSDVATFDFNPAAANDILD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCEEEEECCCHHHHHHHH
KAGYAKASDGNRFTLKLRPAPYFNETRQFGDYLRQALAAIGIDAEIVNADAAAHQKAVYT
HCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHCCEEEC
DHDFDLAVAPPVFRGDPAISTTILVQSGTPDGVPFSNQGGYASLELDKIIKQASETVDTA
CCCCCEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHH
ARTDLYRKFQQLVVADLPLINVAEWGFITVARDTVLNVADNPRWAVANWGDTALQS
HHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCEEECCCCCCEEEECCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]