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The map label for this gene is melR [H]

Identifier: 190894507

GI number: 190894507

Start: 165904

End: 166824

Strand: Reverse

Name: melR [H]

Synonym: RHECIAT_PC0000169

Alternate gene names: 190894507

Gene position: 166824-165904 (Counterclockwise)

Preceding gene: 190894512

Following gene: 190894505

Centisome position: 15.28

GC content: 59.83

Gene sequence:

>921_bases
ATGGATTTGGCGGAAAGTAAGATCGGCACGCATGCAATCTACCAACCCGGCGCAAGCAGTATCGAGGGTTCGCCGACGGC
GCTGCAGATGTTTCATGCCCATCCGCTCGTCATGGCCATGCCGCACTGGCATGCGCAGGTCGAGGTCAACTACGTGATGC
GCGGCACTGTTCATTATCGGATGAGCGATCACGAATTCCGACTGAACGCCGGCGAAATGTGCCTCTTCTGGGGCGGCCAG
CCGCATCAGATGGACGAATCCTCTGATGATTCGCTCTATGCCGGCGCCCATCTGCCGCTCATCTATTTCTTCCGGCTGCG
TCTGCCGATCAGCATTTCCAGCCGGCTGATGAAAGGCGAGACGCTGCTGACCTCGGCAACCGATGCCGCCGACAACGAAA
ATTTCGCTCGCTGGTTCCGCTATGCCAAATCCGGCGATTCCGCCAAGGCCCAGCACGCCGTTGATGAATTGCTGCTGCGC
ATCGAGCGCATTGCGCTCGAACCCTATTCGATGACGACATCGAAGACGACCGTCAGCCTGGAAGGCGATCAGCCACATCC
GAATTCATCGCGCAGCGTCGCGCGCATGTGCGATTTCATCGCCGCCAATTTCCTGCAGGACATTGATTCGGTCGACATCG
CGCGCGCCGCCGATCTGCATCCGAAATATGCGATGAACCTGTTCAAGCGATCGACCGGCATGACGATCAGCAAATATGTG
ACGCTGCTCAGGCTGTCGCGCGCCCAGGCGATGCTGATGAGCGAGGGCGCCAACGTGCTGCAGGTGGCGATGGACAGCGG
CTTCGGCTCGATCAGCGCCTTCAACAAATCCTTCCGGCATATCGCCGGCATGTCGCCATCGGACTTCCGCCGGGATATCC
GGCTGGTGACGACGGTGCCCGCCGGCGCCTTCCAGAACTAG

Upstream 100 bases:

>100_bases
AGTTTGAAGCGCATTGAAAATCCTCCCTTTTCAATTGCCGATCTTTCACGAACCCGGTTAAACTATCCGCAAGGGAGCGG
CTGTCTCCTAAAAAGGGAAC

Downstream 100 bases:

>100_bases
CTGCGATCGTTCCCGGCCGATCGCAACGAGTCGACGCCAGACGTCCGTTTCTCGGCAAGTTCGATCTGAATGCCATCGGG
ATCGCGCAGAAAGGCGACCT

Product: putative AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MDLAESKIGTHAIYQPGASSIEGSPTALQMFHAHPLVMAMPHWHAQVEVNYVMRGTVHYRMSDHEFRLNAGEMCLFWGGQ
PHQMDESSDDSLYAGAHLPLIYFFRLRLPISISSRLMKGETLLTSATDAADNENFARWFRYAKSGDSAKAQHAVDELLLR
IERIALEPYSMTTSKTTVSLEGDQPHPNSSRSVARMCDFIAANFLQDIDSVDIARAADLHPKYAMNLFKRSTGMTISKYV
TLLRLSRAQAMLMSEGANVLQVAMDSGFGSISAFNKSFRHIAGMSPSDFRRDIRLVTTVPAGAFQN

Sequences:

>Translated_306_residues
MDLAESKIGTHAIYQPGASSIEGSPTALQMFHAHPLVMAMPHWHAQVEVNYVMRGTVHYRMSDHEFRLNAGEMCLFWGGQ
PHQMDESSDDSLYAGAHLPLIYFFRLRLPISISSRLMKGETLLTSATDAADNENFARWFRYAKSGDSAKAQHAVDELLLR
IERIALEPYSMTTSKTTVSLEGDQPHPNSSRSVARMCDFIAANFLQDIDSVDIARAADLHPKYAMNLFKRSTGMTISKYV
TLLRLSRAQAMLMSEGANVLQVAMDSGFGSISAFNKSFRHIAGMSPSDFRRDIRLVTTVPAGAFQN
>Mature_306_residues
MDLAESKIGTHAIYQPGASSIEGSPTALQMFHAHPLVMAMPHWHAQVEVNYVMRGTVHYRMSDHEFRLNAGEMCLFWGGQ
PHQMDESSDDSLYAGAHLPLIYFFRLRLPISISSRLMKGETLLTSATDAADNENFARWFRYAKSGDSAKAQHAVDELLLR
IERIALEPYSMTTSKTTVSLEGDQPHPNSSRSVARMCDFIAANFLQDIDSVDIARAADLHPKYAMNLFKRSTGMTISKYV
TLLRLSRAQAMLMSEGANVLQVAMDSGFGSISAFNKSFRHIAGMSPSDFRRDIRLVTTVPAGAFQN

Specific function: Transcription activator for the expression of the melAB operon. MelR binds at two sites located upstream of the melAB transcription site [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790559, Length=257, Percent_Identity=28.7937743190661, Blast_Score=134, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008917
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 34056; Mature: 34056

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLAESKIGTHAIYQPGASSIEGSPTALQMFHAHPLVMAMPHWHAQVEVNYVMRGTVHYR
CCCCHHCCCCCEEECCCCCCCCCCCHHHHHHHCCCEEEECCCCCEEEEEEEEEEEEEEEE
MSDHEFRLNAGEMCLFWGGQPHQMDESSDDSLYAGAHLPLIYFFRLRLPISISSRLMKGE
ECCCEEEECCCCEEEEECCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCHHHHHHCCC
TLLTSATDAADNENFARWFRYAKSGDSAKAQHAVDELLLRIERIALEPYSMTTSKTTVSL
EEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEE
EGDQPHPNSSRSVARMCDFIAANFLQDIDSVDIARAADLHPKYAMNLFKRSTGMTISKYV
ECCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHH
TLLRLSRAQAMLMSEGANVLQVAMDSGFGSISAFNKSFRHIAGMSPSDFRRDIRLVTTVP
HHHHHHHHHHHHHHCCCCEEEEEHHCCCCCHHHHHHHHHHHCCCCHHHHHCCEEEEEECC
AGAFQN
CCCCCC
>Mature Secondary Structure
MDLAESKIGTHAIYQPGASSIEGSPTALQMFHAHPLVMAMPHWHAQVEVNYVMRGTVHYR
CCCCHHCCCCCEEECCCCCCCCCCCHHHHHHHCCCEEEECCCCCEEEEEEEEEEEEEEEE
MSDHEFRLNAGEMCLFWGGQPHQMDESSDDSLYAGAHLPLIYFFRLRLPISISSRLMKGE
ECCCEEEECCCCEEEEECCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCHHHHHHCCC
TLLTSATDAADNENFARWFRYAKSGDSAKAQHAVDELLLRIERIALEPYSMTTSKTTVSL
EEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEE
EGDQPHPNSSRSVARMCDFIAANFLQDIDSVDIARAADLHPKYAMNLFKRSTGMTISKYV
ECCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHH
TLLRLSRAQAMLMSEGANVLQVAMDSGFGSISAFNKSFRHIAGMSPSDFRRDIRLVTTVP
HHHHHHHHHHHHHHCCCCEEEEEHHCCCCCHHHHHHHHHHHCCCCHHHHHCCEEEEEECC
AGAFQN
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]