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The map label for this gene is gntR [H]

Identifier: 190894452

GI number: 190894452

Start: 113098

End: 114045

Strand: Reverse

Name: gntR [H]

Synonym: RHECIAT_PC0000114

Alternate gene names: 190894452

Gene position: 114045-113098 (Counterclockwise)

Preceding gene: 190894460

Following gene: 190894450

Centisome position: 10.45

GC content: 63.29

Gene sequence:

>948_bases
ATGACGGCATCGCGTGCCCTTCGCGGTGCGGCCGACGTCTCCAAGGAGACGCGCGAGAAAGTGCTCCAGCAGGCCGAGCG
GCTGAGCTATGTCGGCAACCGGCTGGCGTTATCGCTGTCGTCACAGCGCACGAACCTCGTCGCCGTCGTCGTTCCGAGCA
TGTCCAACATCGTCTTTCCCGAGATGCTGGCGGGCATTTCGGCCGGATTGCGGGGATCCGGCATGCAGGCGGTGTTCGGC
ATCTCCGACTACGACATGGCGAAGGAGCGCGAGATCATCCGCGACATGCTCTCCTGGCGGCCTGCCGCCATCATCGTGAC
AGGCCTCGACCAGCCGGCAGAAACGGTCAAAATGCTGCGGAATGCGGAGATCCCGGTCATCCAGCTGATGGACCTCGACG
GCACCCCCATCGATTTCAACGTCGGGCTGTCTCACGGGAAGGCGGGAGAGGAAATGGCAAAAGCGCTTTTGGCCGGCGGC
CGGCGGCGGTTTGGCTATATCGGCAGCGCGATCGACAGGGACTTGCGGGCGGGCAAACGCAAGGCCGGTTTTGAGAAGGC
CCTGCGCGAAAGCGGCCTTTCCTTCGTCGATGAGCGGTTCAACGCCGCCTTTTCCTCGGTGGCCCACGGCAAGCGGCTGA
CAATGTCCATGCTCGCGGAGACGCGCGATCTCGATTGCATTTACTATTCCAACGACGACATGGCGACCGGCGGCGTCTTC
GCGTGCCTGGAACTCGGCGTTTCCAGCCCCGCCGACATTCTGATTGCCGGGTTTAACGGGCTTGACGTCGCCCGCGCCCT
CCCCGTCAGGATTGCGACCTCGATCTCCCCGCGCCGTCAGATGGGCGAAGTCGCCGCCGCACTTCTGCTGGCTGCGAGCA
GACGCGACGGAAATCCGCCTGCAGAAAAGATCATTGCTTTCGATCCCGAGATTACCGGCGTCGATTAG

Upstream 100 bases:

>100_bases
AATCTGGTGTTGGCCGCTGGCGAGGCAATTCGACTAAGGAATCGGTTCGATGCGTAAATCCACATTGGAAGAGGTTGCCG
CCGCGGCCGGCGTCAGCAAG

Downstream 100 bases:

>100_bases
GCTCCGGGAATCCCGTCAACAAAGCCGCTCCACCCCGCTTGTGGAATGGCTGATGGCGTCGTCTTCGAAGTCATTCGGCC
GACTAAAGATAAATTCAAAA

Product: putative LacI family transcriptional regulator

Products: NA

Alternate protein names: Gluconate utilization system GNT-I transcriptional repressor [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MTASRALRGAADVSKETREKVLQQAERLSYVGNRLALSLSSQRTNLVAVVVPSMSNIVFPEMLAGISAGLRGSGMQAVFG
ISDYDMAKEREIIRDMLSWRPAAIIVTGLDQPAETVKMLRNAEIPVIQLMDLDGTPIDFNVGLSHGKAGEEMAKALLAGG
RRRFGYIGSAIDRDLRAGKRKAGFEKALRESGLSFVDERFNAAFSSVAHGKRLTMSMLAETRDLDCIYYSNDDMATGGVF
ACLELGVSSPADILIAGFNGLDVARALPVRIATSISPRRQMGEVAAALLLAASRRDGNPPAEKIIAFDPEITGVD

Sequences:

>Translated_315_residues
MTASRALRGAADVSKETREKVLQQAERLSYVGNRLALSLSSQRTNLVAVVVPSMSNIVFPEMLAGISAGLRGSGMQAVFG
ISDYDMAKEREIIRDMLSWRPAAIIVTGLDQPAETVKMLRNAEIPVIQLMDLDGTPIDFNVGLSHGKAGEEMAKALLAGG
RRRFGYIGSAIDRDLRAGKRKAGFEKALRESGLSFVDERFNAAFSSVAHGKRLTMSMLAETRDLDCIYYSNDDMATGGVF
ACLELGVSSPADILIAGFNGLDVARALPVRIATSISPRRQMGEVAAALLLAASRRDGNPPAEKIIAFDPEITGVD
>Mature_314_residues
TASRALRGAADVSKETREKVLQQAERLSYVGNRLALSLSSQRTNLVAVVVPSMSNIVFPEMLAGISAGLRGSGMQAVFGI
SDYDMAKEREIIRDMLSWRPAAIIVTGLDQPAETVKMLRNAEIPVIQLMDLDGTPIDFNVGLSHGKAGEEMAKALLAGGR
RRFGYIGSAIDRDLRAGKRKAGFEKALRESGLSFVDERFNAAFSSVAHGKRLTMSMLAETRDLDCIYYSNDDMATGGVFA
CLELGVSSPADILIAGFNGLDVARALPVRIATSISPRRQMGEVAAALLLAASRRDGNPPAEKIIAFDPEITGVD

Specific function: Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=300, Percent_Identity=33.6666666666667, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1790715, Length=300, Percent_Identity=32.6666666666667, Blast_Score=160, Evalue=9e-41,
Organism=Escherichia coli, GI1788474, Length=322, Percent_Identity=27.0186335403727, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1787948, Length=292, Percent_Identity=24.6575342465753, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789068, Length=303, Percent_Identity=24.0924092409241, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790369, Length=293, Percent_Identity=23.2081911262799, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789202, Length=279, Percent_Identity=25.4480286738351, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790194, Length=301, Percent_Identity=21.2624584717608, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786540, Length=261, Percent_Identity=26.4367816091954, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 33821; Mature: 33690

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASRALRGAADVSKETREKVLQQAERLSYVGNRLALSLSSQRTNLVAVVVPSMSNIVFP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCCCHHHH
EMLAGISAGLRGSGMQAVFGISDYDMAKEREIIRDMLSWRPAAIIVTGLDQPAETVKMLR
HHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHH
NAEIPVIQLMDLDGTPIDFNVGLSHGKAGEEMAKALLAGGRRRFGYIGSAIDRDLRAGKR
CCCCCEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHH
KAGFEKALRESGLSFVDERFNAAFSSVAHGKRLTMSMLAETRDLDCIYYSNDDMATGGVF
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCCCCCCHHH
ACLELGVSSPADILIAGFNGLDVARALPVRIATSISPRRQMGEVAAALLLAASRRDGNPP
HHHHHCCCCCCCEEEECCCCHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
AEKIIAFDPEITGVD
HHCEEEECCCCCCCC
>Mature Secondary Structure 
TASRALRGAADVSKETREKVLQQAERLSYVGNRLALSLSSQRTNLVAVVVPSMSNIVFP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCCCHHHH
EMLAGISAGLRGSGMQAVFGISDYDMAKEREIIRDMLSWRPAAIIVTGLDQPAETVKMLR
HHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHH
NAEIPVIQLMDLDGTPIDFNVGLSHGKAGEEMAKALLAGGRRRFGYIGSAIDRDLRAGKR
CCCCCEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHH
KAGFEKALRESGLSFVDERFNAAFSSVAHGKRLTMSMLAETRDLDCIYYSNDDMATGGVF
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCCCCCCHHH
ACLELGVSSPADILIAGFNGLDVARALPVRIATSISPRRQMGEVAAALLLAASRRDGNPP
HHHHHCCCCCCCEEEECCCCHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
AEKIIAFDPEITGVD
HHCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]