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The map label for this gene is dapA [H]

Identifier: 190894401

GI number: 190894401

Start: 61329

End: 62231

Strand: Reverse

Name: dapA [H]

Synonym: RHECIAT_PC0000063

Alternate gene names: 190894401

Gene position: 62231-61329 (Counterclockwise)

Preceding gene: 190894402

Following gene: 190894400

Centisome position: 5.7

GC content: 64.56

Gene sequence:

>903_bases
ATGGGACTTCAATCGATGACCACCTTTCCCTTCCCAGGACTCAATCTCGCCATCACCACGCCGTTCGACGATGCCGGCCG
CATCGATTACGGGCGGCTCGAAGTCAATATCGAACGCTATCTCGCTGCCGGCGTCCGCAGCTTCCTGCTCAGCTCCGGCA
CCGGCATGCACGTCTATCTCTCCAAGGCCGAATCCGAGGAACTGGTCCGCCGCGGCGCGAGGATCGTCAACGGCCGCGCC
AAGGTGATCGCCCAGACCTCGGCGCTGCTGGTGGAAGATGTGGTGGAGCGGACCGCCCGCGCCCGCGATGCCGGCGCCGA
AGGTGTCATGGTGCTGCCGCCCTTCTTCGAGGGCCCGACCGACGACGAGGGCATTCTTGATTTCTACGCCGAGGTTGCCA
AGGCTGGGCTTCCGGTCATCGGCTATAACGTGCCCCAGGCGGTCGGCGTCGCCATTACACCGGAGCTTCTCGATAAGCTG
AACGCGATCCCGGGCTTCTCGGCCGTCAAGGACAGCAGCGGGGATCTGGGAAAACAGGCGGCGCTCATCCGCACCGGCCG
CTTCGTCATGAATGGCGCCGATCCTCTTGTTCCCTATGCGCTCTATGCCGGATGCGACGGACTGATCTGGGGTGGCGCGA
ACTTCGCACCGAAAACCTCAGTCGCGCTCGTCGAGGCGGCCTCCCAGCGCAAGTGGGACGAGGTTCGCGACCTCTGGAAA
ATCCTCGAGCCGGCGATGGGGCTGATCTGGGAAGGCGATTATGTGCAGTCGGTCTATGCCGCCGCCGATATGGTCGGCTA
TGGCGCCGGCGTGCCGCGCAAGCCGCTGCGCGCGCTTGCTGCCGAAAAGCTGCCGGCGCTGCGGCACTCCCTTGAAGCGC
TCATGGAGCGGGAGGCGATTTAA

Upstream 100 bases:

>100_bases
TACGCGGCCCCGGAAGGGTTGGAGACGCCGACCCTTTGAGCCGCCCGAGATCAATAGACACAGCTCAAGGCAATCTGGCT
CGACCTTTCGGCCTAAGACA

Downstream 100 bases:

>100_bases
CCGTGAGCCGGGCCGCAAAGAACGTCTTCGTCGCATCGAAGCTACCCAAACGCGCCGGCATTTCGGGCTGGGTGGCGACA
CTCCCGCCGCGCATGCCGCG

Product: putative dihydrodipicolinate synthetase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MGLQSMTTFPFPGLNLAITTPFDDAGRIDYGRLEVNIERYLAAGVRSFLLSSGTGMHVYLSKAESEELVRRGARIVNGRA
KVIAQTSALLVEDVVERTARARDAGAEGVMVLPPFFEGPTDDEGILDFYAEVAKAGLPVIGYNVPQAVGVAITPELLDKL
NAIPGFSAVKDSSGDLGKQAALIRTGRFVMNGADPLVPYALYAGCDGLIWGGANFAPKTSVALVEAASQRKWDEVRDLWK
ILEPAMGLIWEGDYVQSVYAAADMVGYGAGVPRKPLRALAAEKLPALRHSLEALMEREAI

Sequences:

>Translated_300_residues
MGLQSMTTFPFPGLNLAITTPFDDAGRIDYGRLEVNIERYLAAGVRSFLLSSGTGMHVYLSKAESEELVRRGARIVNGRA
KVIAQTSALLVEDVVERTARARDAGAEGVMVLPPFFEGPTDDEGILDFYAEVAKAGLPVIGYNVPQAVGVAITPELLDKL
NAIPGFSAVKDSSGDLGKQAALIRTGRFVMNGADPLVPYALYAGCDGLIWGGANFAPKTSVALVEAASQRKWDEVRDLWK
ILEPAMGLIWEGDYVQSVYAAADMVGYGAGVPRKPLRALAAEKLPALRHSLEALMEREAI
>Mature_299_residues
GLQSMTTFPFPGLNLAITTPFDDAGRIDYGRLEVNIERYLAAGVRSFLLSSGTGMHVYLSKAESEELVRRGARIVNGRAK
VIAQTSALLVEDVVERTARARDAGAEGVMVLPPFFEGPTDDEGILDFYAEVAKAGLPVIGYNVPQAVGVAITPELLDKLN
AIPGFSAVKDSSGDLGKQAALIRTGRFVMNGADPLVPYALYAGCDGLIWGGANFAPKTSVALVEAASQRKWDEVRDLWKI
LEPAMGLIWEGDYVQSVYAAADMVGYGAGVPRKPLRALAAEKLPALRHSLEALMEREAI

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=283, Percent_Identity=24.0282685512367, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI13540533, Length=298, Percent_Identity=28.5234899328859, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI1788823, Length=238, Percent_Identity=26.890756302521, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1789620, Length=293, Percent_Identity=26.2798634812287, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786463, Length=225, Percent_Identity=28, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082415, Length=232, Percent_Identity=25.8620689655172, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32168; Mature: 32037

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLQSMTTFPFPGLNLAITTPFDDAGRIDYGRLEVNIERYLAAGVRSFLLSSGTGMHVYL
CCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEEEE
SKAESEELVRRGARIVNGRAKVIAQTSALLVEDVVERTARARDAGAEGVMVLPPFFEGPT
ECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCC
DDEGILDFYAEVAKAGLPVIGYNVPQAVGVAITPELLDKLNAIPGFSAVKDSSGDLGKQA
CCHHHHHHHHHHHHCCCCEEECCCCHHCCCEECHHHHHHHHCCCCCCCCCCCCCCCHHHH
ALIRTGRFVMNGADPLVPYALYAGCDGLIWGGANFAPKTSVALVEAASQRKWDEVRDLWK
HHHHHCCCEECCCCCHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHH
ILEPAMGLIWEGDYVQSVYAAADMVGYGAGVPRKPLRALAAEKLPALRHSLEALMEREAI
HHHHHHHHEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GLQSMTTFPFPGLNLAITTPFDDAGRIDYGRLEVNIERYLAAGVRSFLLSSGTGMHVYL
CCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEEEE
SKAESEELVRRGARIVNGRAKVIAQTSALLVEDVVERTARARDAGAEGVMVLPPFFEGPT
ECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCC
DDEGILDFYAEVAKAGLPVIGYNVPQAVGVAITPELLDKLNAIPGFSAVKDSSGDLGKQA
CCHHHHHHHHHHHHCCCCEEECCCCHHCCCEECHHHHHHHHCCCCCCCCCCCCCCCHHHH
ALIRTGRFVMNGADPLVPYALYAGCDGLIWGGANFAPKTSVALVEAASQRKWDEVRDLWK
HHHHHCCCEECCCCCHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHH
ILEPAMGLIWEGDYVQSVYAAADMVGYGAGVPRKPLRALAAEKLPALRHSLEALMEREAI
HHHHHHHHEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA