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The map label for this gene is era [H]

Identifier: 190571107

GI number: 190571107

Start: 772370

End: 773254

Strand: Direct

Name: era [H]

Synonym: WPa_0705

Alternate gene names: 190571107

Gene position: 772370-773254 (Clockwise)

Preceding gene: 190571106

Following gene: 190571108

Centisome position: 52.1

GC content: 35.37

Gene sequence:

>885_bases
GTGAAAGAAGAAAAATGCTTATTTGTAACGATAGCTGGTTTGCCAAATGCTGGAAAGTCAACGCTAATTAACAGCATCGT
AGGCAAGAAAATTGCAATTGTCACCCCTAAAGTGCAGACAACAAGGACACAGGTAAGGGGTGTTGCTATATGCAACAATG
CGCAAATTGTTTTTACTGACTCTCCGGGAGTGTTTTCAGCAGAAACAAATCTTGAAAAAGCTTTAGTCAAATCTGCATGG
GGAGCAGTTAAGGATAGTGACATTACTTTATTGCTTGTTGATGTAAACAATTACCTAAAAAATATAGAAAGAATAAAAAC
GATATTTGCACGACTGGAGCGCACAAAAGGCAGATGCATTTTGGTTATCAATAAAACTGATTTAGTAAAGAAATCAGAGC
TCAAGATGGCACATGAGCACCTAAATTTGCTTTATAAGTTTGAAAAAATTTTTACGATCTCGGCACTGAAGAATGATGGA
CTTTCTGATCTGACTAGTTACTTGTCTGAAATTGCACCGATAGGCCCTTGGTTTTATGAAAAAGATCAAATAACTGATTC
CTCAGCTGATTTTTTATCAGCGGAAATTACGAGAGAAAAGTTATTCTTGAACCTACGTGAAGAATTGCCATACTCTACAG
CTGTTATAACTGAACAATTTGAGGAAAAAAAAGATAAGAGTTTAGTCATAAAACAGATCATATTTGTATTGAAAGATAAT
CATAAGAAAATAGTGCTAGGAAAAGACGGCAGTAGCATAAAAAAAATTAATATCGAGGCGCGTACAGAATTGGAAAAGTT
ATTTGAGTGTAAAGTTCATCTCTTTTTGTTCGTAAAAGTGCGACCTTGGACTGATCGCCCTGAGGAATATATAAGTAATG
CTTAA

Upstream 100 bases:

>100_bases
CACCTATAGTTGAGCGTTTTTCTTCAAAAGAGGAAGAGTGCAATCTACCTGCAAAATAATCAATTGACGTTAGCATTTAG
TTTTCTTTATAATTTCCTTT

Downstream 100 bases:

>100_bases
TTCTTTGTTAGTATTTGATATTGAAACTATACCAGATGTAAATTCCTGCAAGAATTTACTAAATATTAGTGATGATAGCA
GTGTAGAAGAAAAGAGGAAC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MKEEKCLFVTIAGLPNAGKSTLINSIVGKKIAIVTPKVQTTRTQVRGVAICNNAQIVFTDSPGVFSAETNLEKALVKSAW
GAVKDSDITLLLVDVNNYLKNIERIKTIFARLERTKGRCILVINKTDLVKKSELKMAHEHLNLLYKFEKIFTISALKNDG
LSDLTSYLSEIAPIGPWFYEKDQITDSSADFLSAEITREKLFLNLREELPYSTAVITEQFEEKKDKSLVIKQIIFVLKDN
HKKIVLGKDGSSIKKINIEARTELEKLFECKVHLFLFVKVRPWTDRPEEYISNA

Sequences:

>Translated_294_residues
MKEEKCLFVTIAGLPNAGKSTLINSIVGKKIAIVTPKVQTTRTQVRGVAICNNAQIVFTDSPGVFSAETNLEKALVKSAW
GAVKDSDITLLLVDVNNYLKNIERIKTIFARLERTKGRCILVINKTDLVKKSELKMAHEHLNLLYKFEKIFTISALKNDG
LSDLTSYLSEIAPIGPWFYEKDQITDSSADFLSAEITREKLFLNLREELPYSTAVITEQFEEKKDKSLVIKQIIFVLKDN
HKKIVLGKDGSSIKKINIEARTELEKLFECKVHLFLFVKVRPWTDRPEEYISNA
>Mature_294_residues
MKEEKCLFVTIAGLPNAGKSTLINSIVGKKIAIVTPKVQTTRTQVRGVAICNNAQIVFTDSPGVFSAETNLEKALVKSAW
GAVKDSDITLLLVDVNNYLKNIERIKTIFARLERTKGRCILVINKTDLVKKSELKMAHEHLNLLYKFEKIFTISALKNDG
LSDLTSYLSEIAPIGPWFYEKDQITDSSADFLSAEITREKLFLNLREELPYSTAVITEQFEEKKDKSLVIKQIIFVLKDN
HKKIVLGKDGSSIKKINIEARTELEKLFECKVHLFLFVKVRPWTDRPEEYISNA

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=324, Percent_Identity=29.9382716049383, Blast_Score=125, Evalue=4e-29,
Organism=Escherichia coli, GI1788919, Length=283, Percent_Identity=33.5689045936396, Blast_Score=159, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24646434, Length=307, Percent_Identity=24.1042345276873, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 33338; Mature: 33338

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEEKCLFVTIAGLPNAGKSTLINSIVGKKIAIVTPKVQTTRTQVRGVAICNNAQIVFTD
CCCCCEEEEEEECCCCCCHHHHHHHHHCCEEEEECCCCHHHHHHHCEEEEECCCEEEEEC
SPGVFSAETNLEKALVKSAWGAVKDSDITLLLVDVNNYLKNIERIKTIFARLERTKGRCI
CCCCEECCCHHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEE
LVINKTDLVKKSELKMAHEHLNLLYKFEKIFTISALKNDGLSDLTSYLSEIAPIGPWFYE
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEHHCCCCHHHHHHHHHHHCCCCCCCCC
KDQITDSSADFLSAEITREKLFLNLREELPYSTAVITEQFEEKKDKSLVIKQIIFVLKDN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HKKIVLGKDGSSIKKINIEARTELEKLFECKVHLFLFVKVRPWTDRPEEYISNA
CCEEEEECCCCCEEEEEEHHHHHHHHHHHCEEEEEEEEEEECCCCCHHHHHCCC
>Mature Secondary Structure
MKEEKCLFVTIAGLPNAGKSTLINSIVGKKIAIVTPKVQTTRTQVRGVAICNNAQIVFTD
CCCCCEEEEEEECCCCCCHHHHHHHHHCCEEEEECCCCHHHHHHHCEEEEECCCEEEEEC
SPGVFSAETNLEKALVKSAWGAVKDSDITLLLVDVNNYLKNIERIKTIFARLERTKGRCI
CCCCEECCCHHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEE
LVINKTDLVKKSELKMAHEHLNLLYKFEKIFTISALKNDGLSDLTSYLSEIAPIGPWFYE
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEHHCCCCHHHHHHHHHHHCCCCCCCCC
KDQITDSSADFLSAEITREKLFLNLREELPYSTAVITEQFEEKKDKSLVIKQIIFVLKDN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HKKIVLGKDGSSIKKINIEARTELEKLFECKVHLFLFVKVRPWTDRPEEYISNA
CCEEEEECCCCCEEEEEEHHHHHHHHHHHCEEEEEEEEEEECCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA