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The map label for this gene is dnaX [H]

Identifier: 190570594

GI number: 190570594

Start: 138683

End: 139534

Strand: Reverse

Name: dnaX [H]

Synonym: WPa_0132

Alternate gene names: 190570594

Gene position: 139534-138683 (Counterclockwise)

Preceding gene: 190570595

Following gene: 190570593

Centisome position: 9.41

GC content: 31.34

Gene sequence:

>852_bases
ATGAAAAAGGTGATAGGCCACAACCAAGCAAAAAAAAAGATAATGAACAACTTGTCTGTTCAATCTTGGCTGATCTGTGG
TAAAAAAGGCATAGGAAAAGCAACACTTGCACAATCCTTTTCTAATTGGTTTCTTATCAAAAATTACGATGAAGTAGCAT
TAGACTTACACATTGTTGAAGGTGATACAATAGGAGTGGAAAAGGTGAGAGAAATGAAAAATTTTCTGTACCTAAGCCCC
ATTCAATCAGAATATAAGATAGCTATAATAGATAGCTTGGAGGCAATGACTAGCAATGCTAAAAATGCAATATTAAAGAT
ATTAGAGGAGCCGCCACAAAATTCTAAAATACTTATAATTAGCCATAAACTATATGATATACAAACCACCATCCGGTGTA
GGTGCTTTCAGCTGAATTTACTTCCGTTAACTTACGATGAAACAAAGCAGGTTGTTTCATCTCAGTGTAAATTCGACGAT
AAAATATTTAGTGAGATCATTACTTTGTTTCCTGGAACTCCGGGAGTAATAATAAATGCAATAAACAGTGGTGCTTATGA
GTCACATAAGCATTTTTATACATTTTTCCGTAATCTAAATAATTCTGATATAGTTAATAAAATAATTAATAGTGAAATTG
AGCTAGAACTAGCATCACATATCATTCAAACCTCCATTTTAGAAAGTATAAAGAAAGAAGTAAATAATGTTGAAATTTTG
CTAAGTCAATGGAAAGAAATAGATGAACTTTTCGTTGCTGCAAAGCAATTTCGCTTAGATAAAAAGCATGTTTTAGCTAA
TGTAGTTAACATCATGACACAAAAATATAATACTTTTAACATAAATTCATGA

Upstream 100 bases:

>100_bases
TTGACTTAACTGGAGACAAGATTAAGGTTTTAAGAAAAGGTAAAATTTCATTACAAACAATAAATAACGAATTTTCAAAC
TAAGATCTATAGGAGAAAGA

Downstream 100 bases:

>100_bases
TAAAATCCTGATAATTTAATACTTAAAGTATATAGTTTGACTGATAATAAATTAACTTTATGGCAATCAATAGAAGTTTT
AACAAAAACCATATTGAACA

Product: Putative DNA polymerase III, gamma/tau subunits

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MKKVIGHNQAKKKIMNNLSVQSWLICGKKGIGKATLAQSFSNWFLIKNYDEVALDLHIVEGDTIGVEKVREMKNFLYLSP
IQSEYKIAIIDSLEAMTSNAKNAILKILEEPPQNSKILIISHKLYDIQTTIRCRCFQLNLLPLTYDETKQVVSSQCKFDD
KIFSEIITLFPGTPGVIINAINSGAYESHKHFYTFFRNLNNSDIVNKIINSEIELELASHIIQTSILESIKKEVNNVEIL
LSQWKEIDELFVAAKQFRLDKKHVLANVVNIMTQKYNTFNINS

Sequences:

>Translated_283_residues
MKKVIGHNQAKKKIMNNLSVQSWLICGKKGIGKATLAQSFSNWFLIKNYDEVALDLHIVEGDTIGVEKVREMKNFLYLSP
IQSEYKIAIIDSLEAMTSNAKNAILKILEEPPQNSKILIISHKLYDIQTTIRCRCFQLNLLPLTYDETKQVVSSQCKFDD
KIFSEIITLFPGTPGVIINAINSGAYESHKHFYTFFRNLNNSDIVNKIINSEIELELASHIIQTSILESIKKEVNNVEIL
LSQWKEIDELFVAAKQFRLDKKHVLANVVNIMTQKYNTFNINS
>Mature_283_residues
MKKVIGHNQAKKKIMNNLSVQSWLICGKKGIGKATLAQSFSNWFLIKNYDEVALDLHIVEGDTIGVEKVREMKNFLYLSP
IQSEYKIAIIDSLEAMTSNAKNAILKILEEPPQNSKILIISHKLYDIQTTIRCRCFQLNLLPLTYDETKQVVSSQCKFDD
KIFSEIITLFPGTPGVIINAINSGAYESHKHFYTFFRNLNNSDIVNKIINSEIELELASHIIQTSILESIKKEVNNVEIL
LSQWKEIDELFVAAKQFRLDKKHVLANVVNIMTQKYNTFNINS

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 32354; Mature: 32354

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVIGHNQAKKKIMNNLSVQSWLICGKKGIGKATLAQSFSNWFLIKNYDEVALDLHIVE
CCCCCCCCHHHHHHHHCCCHHHHEEECCCCCCHHHHHHHHHCEEEEECCCCEEEEEEEEC
GDTIGVEKVREMKNFLYLSPIQSEYKIAIIDSLEAMTSNAKNAILKILEEPPQNSKILII
CCCCCHHHHHHHHHHEEECCCCCCEEEEEEEHHHHHHCCHHHHHHHHHHCCCCCCEEEEE
SHKLYDIQTTIRCRCFQLNLLPLTYDETKQVVSSQCKFDDKIFSEIITLFPGTPGVIINA
EEEEEEHHHEEEEEEEEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEE
INSGAYESHKHFYTFFRNLNNSDIVNKIINSEIELELASHIIQTSILESIKKEVNNVEIL
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSQWKEIDELFVAAKQFRLDKKHVLANVVNIMTQKYNTFNINS
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEECCCC
>Mature Secondary Structure
MKKVIGHNQAKKKIMNNLSVQSWLICGKKGIGKATLAQSFSNWFLIKNYDEVALDLHIVE
CCCCCCCCHHHHHHHHCCCHHHHEEECCCCCCHHHHHHHHHCEEEEECCCCEEEEEEEEC
GDTIGVEKVREMKNFLYLSPIQSEYKIAIIDSLEAMTSNAKNAILKILEEPPQNSKILII
CCCCCHHHHHHHHHHEEECCCCCCEEEEEEEHHHHHHCCHHHHHHHHHHCCCCCCEEEEE
SHKLYDIQTTIRCRCFQLNLLPLTYDETKQVVSSQCKFDDKIFSEIITLFPGTPGVIINA
EEEEEEHHHEEEEEEEEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEE
INSGAYESHKHFYTFFRNLNNSDIVNKIINSEIELELASHIIQTSILESIKKEVNNVEIL
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSQWKEIDELFVAAKQFRLDKKHVLANVVNIMTQKYNTFNINS
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]