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The map label for this gene is ywlC [H]

Identifier: 190570595

GI number: 190570595

Start: 139552

End: 140139

Strand: Reverse

Name: ywlC [H]

Synonym: WPa_0133

Alternate gene names: 190570595

Gene position: 140139-139552 (Counterclockwise)

Preceding gene: 190570596

Following gene: 190570594

Centisome position: 9.45

GC content: 29.42

Gene sequence:

>588_bases
ATGGTATTTGAAGTAATAAATGCAATAAAAAATAATTTGTTAGCATGCTTTCCAACAGAGACAGTATATGCTCTTGCTTG
TAATGCGCTAGGTAAAGAATCTATAGAAAAAATATACCGGATAAAGAAGCGTTCTCAAAACAAGCCACTCTCTATATTTG
TTAGTGATGTTGATAGTTTGACAAATATAGCAAAGGTAAAAGAAGAATATATCAATTTAATAAACTACTTTTCTCCTGGA
CCAATGACCTATATTTTACCACTTCAAGATAACAGTATATTACCAAATGAGTTCTTTAAAGATAGTATAGGCATAAGAAT
TCCTGATCATCCTATTGCGATTTCAATATTAAATGAACTGAAAACTCCAGTAGTTGCAACTAGTATTAACATTTCAGGAG
AAAAAAGTATATGCAAAGCAAGAGATATACCTCAGTCTATTAAGCAACACTTATCTGCAGTAATTGAAGATGATGAATTA
GTTTCTGGTATAGAATCTACTATTATTGACTTAACTGGAGACAAGATTAAGGTTTTAAGAAAAGGTAAAATTTCATTACA
AACAATAAATAACGAATTTTCAAACTAA

Upstream 100 bases:

>100_bases
TCTGTAAGTATACAACAGTAGCCATTTCGGTATCTTAATTGCTACCATATAGCGAGATAACTGTAAACCCAGAGCTATTG
TAGACATAAGTTTTAGCTAT

Downstream 100 bases:

>100_bases
GATCTATAGGAGAAAGAATGAAAAAGGTGATAGGCCACAACCAAGCAAAAAAAAAGATAATGAACAACTTGTCTGTTCAA
TCTTGGCTGATCTGTGGTAA

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MVFEVINAIKNNLLACFPTETVYALACNALGKESIEKIYRIKKRSQNKPLSIFVSDVDSLTNIAKVKEEYINLINYFSPG
PMTYILPLQDNSILPNEFFKDSIGIRIPDHPIAISILNELKTPVVATSINISGEKSICKARDIPQSIKQHLSAVIEDDEL
VSGIESTIIDLTGDKIKVLRKGKISLQTINNEFSN

Sequences:

>Translated_195_residues
MVFEVINAIKNNLLACFPTETVYALACNALGKESIEKIYRIKKRSQNKPLSIFVSDVDSLTNIAKVKEEYINLINYFSPG
PMTYILPLQDNSILPNEFFKDSIGIRIPDHPIAISILNELKTPVVATSINISGEKSICKARDIPQSIKQHLSAVIEDDEL
VSGIESTIIDLTGDKIKVLRKGKISLQTINNEFSN
>Mature_195_residues
MVFEVINAIKNNLLACFPTETVYALACNALGKESIEKIYRIKKRSQNKPLSIFVSDVDSLTNIAKVKEEYINLINYFSPG
PMTYILPLQDNSILPNEFFKDSIGIRIPDHPIAISILNELKTPVVATSINISGEKSICKARDIPQSIKQHLSAVIEDDEL
VSGIESTIIDLTGDKIKVLRKGKISLQTINNEFSN

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=185, Percent_Identity=27.027027027027, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI87081864, Length=186, Percent_Identity=25.2688172043011, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI2367210, Length=139, Percent_Identity=26.6187050359712, Blast_Score=63, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17537239, Length=183, Percent_Identity=32.2404371584699, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321269, Length=191, Percent_Identity=29.8429319371728, Blast_Score=83, Evalue=3e-17,
Organism=Drosophila melanogaster, GI78707274, Length=179, Percent_Identity=31.2849162011173, Blast_Score=77, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 21706; Mature: 21706

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFEVINAIKNNLLACFPTETVYALACNALGKESIEKIYRIKKRSQNKPLSIFVSDVDSL
CHHHHHHHHHHCEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHH
TNIAKVKEEYINLINYFSPGPMTYILPLQDNSILPNEFFKDSIGIRIPDHPIAISILNEL
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHCCCCCEECCCCHHHHHHHHH
KTPVVATSINISGEKSICKARDIPQSIKQHLSAVIEDDELVSGIESTIIDLTGDKIKVLR
CCCEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEC
KGKISLQTINNEFSN
CCCEEEEECCCCCCC
>Mature Secondary Structure
MVFEVINAIKNNLLACFPTETVYALACNALGKESIEKIYRIKKRSQNKPLSIFVSDVDSL
CHHHHHHHHHHCEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHH
TNIAKVKEEYINLINYFSPGPMTYILPLQDNSILPNEFFKDSIGIRIPDHPIAISILNEL
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHCCCCCEECCCCHHHHHHHHH
KTPVVATSINISGEKSICKARDIPQSIKQHLSAVIEDDELVSGIESTIIDLTGDKIKVLR
CCCEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEC
KGKISLQTINNEFSN
CCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]