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The map label for this gene is coaD [H]

Identifier: 190570529

GI number: 190570529

Start: 52984

End: 53490

Strand: Direct

Name: coaD [H]

Synonym: WPa_0057

Alternate gene names: 190570529

Gene position: 52984-53490 (Clockwise)

Preceding gene: 190570526

Following gene: 190570530

Centisome position: 3.57

GC content: 34.12

Gene sequence:

>507_bases
ATGAACATTAGTAACAAAATAGGAATTTATCCTGGTACATTTGACCCCATAACTTTTGGGCACCTTGACATAATAAAAAG
AGCATGTAAGCTAGTCGATAAGTTGATAATTGGTGTTGCAGAGAATGTTAATAAACATACTAATTTTGACATAAGACTGC
GCACAAGCATGGCTAAAAATGAAGTGAAAGGAGCAGGAATTGATGCAGATATTATATCCTTTAATGGGTTGCTAGTGAAG
TTTGCCAAAGAGCAAAATGCTTCTGTTATTATTAGAGGACTGAGAGCAGTATCGGATTTTGATTACGAGTTTCAAATGAG
TTGGGTAAATTATAAGCTCTTTCCTGAAATCGAAACTATATTTCTTCCTGCATCTGAGGATACTCAATTTATCTCATCAA
GTTTTGTAAAGGAAATAGCGAGATTAGGAGGAGATGTTAGCAACTTTGTGTCAAAAAGTGTCCAAAGTGAATTGATTAAT
CTAAATAGGGTAGAAAATGGAGAATAA

Upstream 100 bases:

>100_bases
TGCTCTACCAACTGAGCTATCAGGCCAACTACGTACTTTCATTTTTAGATAAAAAACGTTATCATGTCCATCAAAAGTTT
TTGAAGTATAGAAACAAAGA

Downstream 100 bases:

>100_bases
GTATTTGTTGTCTTTTTTATTTCCAAACGAGTATGTTAGATGTGTAAAATATTGTAAGCTAAAGGAGAGACATGTTAAAA
GTGAGGGATAATAATGTAAT

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MNISNKIGIYPGTFDPITFGHLDIIKRACKLVDKLIIGVAENVNKHTNFDIRLRTSMAKNEVKGAGIDADIISFNGLLVK
FAKEQNASVIIRGLRAVSDFDYEFQMSWVNYKLFPEIETIFLPASEDTQFISSSFVKEIARLGGDVSNFVSKSVQSELIN
LNRVENGE

Sequences:

>Translated_168_residues
MNISNKIGIYPGTFDPITFGHLDIIKRACKLVDKLIIGVAENVNKHTNFDIRLRTSMAKNEVKGAGIDADIISFNGLLVK
FAKEQNASVIIRGLRAVSDFDYEFQMSWVNYKLFPEIETIFLPASEDTQFISSSFVKEIARLGGDVSNFVSKSVQSELIN
LNRVENGE
>Mature_168_residues
MNISNKIGIYPGTFDPITFGHLDIIKRACKLVDKLIIGVAENVNKHTNFDIRLRTSMAKNEVKGAGIDADIISFNGLLVK
FAKEQNASVIIRGLRAVSDFDYEFQMSWVNYKLFPEIETIFLPASEDTQFISSSFVKEIARLGGDVSNFVSKSVQSELIN
LNRVENGE

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=155, Percent_Identity=43.8709677419355, Blast_Score=152, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 18779; Mature: 18779

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNISNKIGIYPGTFDPITFGHLDIIKRACKLVDKLIIGVAENVNKHTNFDIRLRTSMAKN
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHH
EVKGAGIDADIISFNGLLVKFAKEQNASVIIRGLRAVSDFDYEFQMSWVNYKLFPEIETI
HCCCCCCCHHEEECCCEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEEEEEECCCEEEE
FLPASEDTQFISSSFVKEIARLGGDVSNFVSKSVQSELINLNRVENGE
EEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNISNKIGIYPGTFDPITFGHLDIIKRACKLVDKLIIGVAENVNKHTNFDIRLRTSMAKN
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHH
EVKGAGIDADIISFNGLLVKFAKEQNASVIIRGLRAVSDFDYEFQMSWVNYKLFPEIETI
HCCCCCCCHHEEECCCEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEEEEEECCCEEEE
FLPASEDTQFISSSFVKEIARLGGDVSNFVSKSVQSELINLNRVENGE
EEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA