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The map label for this gene is ubiH [C]

Identifier: 190570526

GI number: 190570526

Start: 48381

End: 49538

Strand: Direct

Name: ubiH [C]

Synonym: WPa_0053

Alternate gene names: 190570526

Gene position: 48381-49538 (Clockwise)

Preceding gene: 190570524

Following gene: 190570529

Centisome position: 3.26

GC content: 34.28

Gene sequence:

>1158_bases
ATGAATTACGATGTAATCATTTCAGGTAGTGGGCTAATTGGTCTTATTACTGCTATTGGCCTGAGTAATGACTCTGTATC
TGTAGCCGTAATTGAGAAAAATAGTTTACCACGTGCAGTTGATGATAATCGAGCATTTGCCATTTCTCAAGGATCAAAAA
AAATACTAGAAAAATTAGGGATTTGGCGGCTCTTAGAAGGCGAAACTGAACCAATACTTGATATATGCATATTAGATGGA
GATAGTCCATTTACTGTGCATTATGACCATAAAATGGTTGGTGAAGAGCCAATGGGCTATGTAATCAAGAGCGCTATTAT
ATGGAATGCAATCAATAAAAATTTTTTGCATAAACTCAATATATATTCTCCACGTTCCTATAAAACAATCTCTTGTGACG
AAGGATACATGGAAGTTACTCTTGATAATGATCAAAAATTGATATCATCACTATTTATCTGTGCTGAAGGTAAAAACTCT
AGGTTGCCAGAGTTGTTTTCTATACCAATGATAAAATTTGATTATAAACAAAATAGCATGGTATTTAATGTAAAACATGA
ATTACATCACCAAAACTTAGCTGTAGAGCGGTTTTTTCCTGGTGGTCCATTTGCAATTTTGCCAATGAAAGGTGGCTATA
CTTCTTCAATAGTTTGGACAGAAAAATGCGAAATTTCAAAAATGCTGATGAGCTTATCCGAAGAGGAATTTGTCATAGAA
CTCAAAAAAAGATTTGGTTCTTATTTGGGAGAAATTGAATTAGAGGGTGAAAGAAGATTCTATCCTTTGAGTTTTTCTTT
TGCAAGAAAGCTGCATAAAAGCAGAATTTTGCTGATTGGCGATGCAGCACATTCAATCCACCCGGTTGCAGGTCAAGGAC
TTAACCTTGGAATGAGAGATGTAGAGAGTGTTATTAGACAAATAACTGCTGCAAAATCCTCTGGCATTGATGTTGGCAGT
AATTATCTATTGAAGAAAATTTCATATGACAGATACTTTGATAATTTTACTATGGCACTTGCAACTGATGGACTAAATAG
AATATTTTCCAACAGAATACTTTGCGCTCAAGTTCTGAGAAATCTTGGTTTAATGGTAGTTGAAAATTCAGATTTTCTTA
AAAAAAGCTTCGTTCGACATGCTATGGGGTTTATATAA

Upstream 100 bases:

>100_bases
TATTTTGGTTATAACTAAGATAGTAATGAGAAGTTCAGTGTCTACAAAGTTCGTTTAAACTATTTTCAAAATGGGTATAA
TATAATTTTAGGTTAATAAA

Downstream 100 bases:

>100_bases
ATCATTAGATTTCTTTCATCATAATCAGGTATCATTAGAGTAGTTGACACTGGAGCTCAAATTCCATAATGTCATGCCAG
TGCCCAGACACTGGCATCCA

Product: 2-polyprenyl-6-methoxyphenol hydroxylase, fad-dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MNYDVIISGSGLIGLITAIGLSNDSVSVAVIEKNSLPRAVDDNRAFAISQGSKKILEKLGIWRLLEGETEPILDICILDG
DSPFTVHYDHKMVGEEPMGYVIKSAIIWNAINKNFLHKLNIYSPRSYKTISCDEGYMEVTLDNDQKLISSLFICAEGKNS
RLPELFSIPMIKFDYKQNSMVFNVKHELHHQNLAVERFFPGGPFAILPMKGGYTSSIVWTEKCEISKMLMSLSEEEFVIE
LKKRFGSYLGEIELEGERRFYPLSFSFARKLHKSRILLIGDAAHSIHPVAGQGLNLGMRDVESVIRQITAAKSSGIDVGS
NYLLKKISYDRYFDNFTMALATDGLNRIFSNRILCAQVLRNLGLMVVENSDFLKKSFVRHAMGFI

Sequences:

>Translated_385_residues
MNYDVIISGSGLIGLITAIGLSNDSVSVAVIEKNSLPRAVDDNRAFAISQGSKKILEKLGIWRLLEGETEPILDICILDG
DSPFTVHYDHKMVGEEPMGYVIKSAIIWNAINKNFLHKLNIYSPRSYKTISCDEGYMEVTLDNDQKLISSLFICAEGKNS
RLPELFSIPMIKFDYKQNSMVFNVKHELHHQNLAVERFFPGGPFAILPMKGGYTSSIVWTEKCEISKMLMSLSEEEFVIE
LKKRFGSYLGEIELEGERRFYPLSFSFARKLHKSRILLIGDAAHSIHPVAGQGLNLGMRDVESVIRQITAAKSSGIDVGS
NYLLKKISYDRYFDNFTMALATDGLNRIFSNRILCAQVLRNLGLMVVENSDFLKKSFVRHAMGFI
>Mature_385_residues
MNYDVIISGSGLIGLITAIGLSNDSVSVAVIEKNSLPRAVDDNRAFAISQGSKKILEKLGIWRLLEGETEPILDICILDG
DSPFTVHYDHKMVGEEPMGYVIKSAIIWNAINKNFLHKLNIYSPRSYKTISCDEGYMEVTLDNDQKLISSLFICAEGKNS
RLPELFSIPMIKFDYKQNSMVFNVKHELHHQNLAVERFFPGGPFAILPMKGGYTSSIVWTEKCEISKMLMSLSEEEFVIE
LKKRFGSYLGEIELEGERRFYPLSFSFARKLHKSRILLIGDAAHSIHPVAGQGLNLGMRDVESVIRQITAAKSSGIDVGS
NYLLKKISYDRYFDNFTMALATDGLNRIFSNRILCAQVLRNLGLMVVENSDFLKKSFVRHAMGFI

Specific function: Not Yet Known. [C]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=385, Percent_Identity=26.4935064935065, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI32967307, Length=329, Percent_Identity=27.355623100304, Blast_Score=125, Evalue=9e-29,
Organism=Escherichia coli, GI1789273, Length=390, Percent_Identity=29.7435897435897, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI1789274, Length=395, Percent_Identity=30.379746835443, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1786883, Length=390, Percent_Identity=29.2307692307692, Blast_Score=167, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI25146631, Length=416, Percent_Identity=25.7211538461538, Blast_Score=123, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321694, Length=275, Percent_Identity=26.5454545454545, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI19920760, Length=433, Percent_Identity=24.9422632794457, Blast_Score=130, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 43344; Mature: 43344

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYDVIISGSGLIGLITAIGLSNDSVSVAVIEKNSLPRAVDDNRAFAISQGSKKILEKLG
CCEEEEEECCCCEEEHHHHCCCCCCEEEEEEECCCCCCCCCCCCEEEECCCHHHHHHHCC
IWRLLEGETEPILDICILDGDSPFTVHYDHKMVGEEPMGYVIKSAIIWNAINKNFLHKLN
CEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCHHHHHEEE
IYSPRSYKTISCDEGYMEVTLDNDQKLISSLFICAEGKNSRLPELFSIPMIKFDYKQNSM
CCCCCCCEEEECCCCEEEEEECCHHHHHHHHEEEECCCCCCCCHHHCCCEEEEECCCCCE
VFNVKHELHHQNLAVERFFPGGPFAILPMKGGYTSSIVWTEKCEISKMLMSLSEEEFVIE
EEEEHHHHCCCCEEEEEECCCCCEEEEEECCCCCCEEEEECHHHHHHHHHHCCCHHHHHH
LKKRFGSYLGEIELEGERRFYPLSFSFARKLHKSRILLIGDAAHSIHPVAGQGLNLGMRD
HHHHHHHHHCEEEECCCCEEEEECHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCHHH
VESVIRQITAAKSSGIDVGSNYLLKKISYDRYFDNFTMALATDGLNRIFSNRILCAQVLR
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHCCHHHHHHHH
NLGLMVVENSDFLKKSFVRHAMGFI
HCCEEEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNYDVIISGSGLIGLITAIGLSNDSVSVAVIEKNSLPRAVDDNRAFAISQGSKKILEKLG
CCEEEEEECCCCEEEHHHHCCCCCCEEEEEEECCCCCCCCCCCCEEEECCCHHHHHHHCC
IWRLLEGETEPILDICILDGDSPFTVHYDHKMVGEEPMGYVIKSAIIWNAINKNFLHKLN
CEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCHHHHHEEE
IYSPRSYKTISCDEGYMEVTLDNDQKLISSLFICAEGKNSRLPELFSIPMIKFDYKQNSM
CCCCCCCEEEECCCCEEEEEECCHHHHHHHHEEEECCCCCCCCHHHCCCEEEEECCCCCE
VFNVKHELHHQNLAVERFFPGGPFAILPMKGGYTSSIVWTEKCEISKMLMSLSEEEFVIE
EEEEHHHHCCCCEEEEEECCCCCEEEEEECCCCCCEEEEECHHHHHHHHHHCCCHHHHHH
LKKRFGSYLGEIELEGERRFYPLSFSFARKLHKSRILLIGDAAHSIHPVAGQGLNLGMRD
HHHHHHHHHCEEEECCCCEEEEECHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCHHH
VESVIRQITAAKSSGIDVGSNYLLKKISYDRYFDNFTMALATDGLNRIFSNRILCAQVLR
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHCCHHHHHHHH
NLGLMVVENSDFLKKSFVRHAMGFI
HCCEEEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]