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The map label for this gene is eryA [H]

Identifier: 189424600

GI number: 189424600

Start: 1621828

End: 1629471

Strand: Reverse

Name: eryA [H]

Synonym: Glov_1541

Alternate gene names: 189424600

Gene position: 1629471-1621828 (Counterclockwise)

Preceding gene: 189424602

Following gene: 189424599

Centisome position: 41.59

GC content: 52.15

Gene sequence:

>7644_bases
ATGCCACCAACTGTTGCCATCATTGGATTTTCATTCAGACTGCCCAACACTACTCAAGAAGCGTTCTGGAACGACCTGTT
ACAAGGTCGTGATCTGGTAACAAGTGTTCCGAATAACCGTTGGAGCCAGGAAACATTTTATCATCCAGACAAGGATCACC
CCGGAGCCAGTTACTCCTTCACAGCCGGCCCAATTGGCGATGTTTCACTCTTTGACGCAGGTTTTTTTGGTATTTCTCCA
CGTGAAGCTGCTGTCATGGATCCTCAACAACGCCTGTTACTAGAGCTTGGCTGGGAAGCTTGTGAACACGCCGGAATAAA
ACCTTCATCCTTAAGGGGTAGCCGATGCGGCGTCTATATTGGAGTTTCGAATATCGACTATGCCTTTCGCCTCACTGACG
ATCTCGCAGCGATCGACTCCTCTTCCGGGACAGGAAACACCTCAAGCATTGCCGCAAATCGCCTCTCGTACTTCTTTGAC
CTGCACGGTCCCAGTATGGCAATCGATACAGCCTGCTCATCCTCGTTGGTTGCCTTTCACCAAGCTTGTGTATCCATAGC
ATCAGGCGAAAGCAGTATGGCCTTGGCAGGAGGGGTCAGCCTGCACCTACACCCGTATACATTTGTTGCTTTTTCTAAGG
CATCCATGCTGTCTAAACAAGGCCATTGCAACGTGTTTGACGCAGCATGCGATGGCTATGTCCGCTCTGAAGGTGCCGGC
CTGTTTCTGCTGAAAGAGTACAATCAGGCTGTGGCTGATGGAGACCAGATACTGGCTGTAGTGGCTGCCTCTGCAGTCAA
TACGGATGGCCGGAAATCAGGTTTGACCGTACCAAGTGCAAAAGCTCAGTCAACCCTCTTGAAGCAAGCCTATCTGCGAG
CCGGCATAGCGCCTGCAGAGATTGACTACATTGAGGCACATGGCACCGGTACTACTGTTGGCGACCCCATAGAAGTGCAG
GCTATTGGTGAAGCATTGGGCAAACAGCGCCCCGAAGGAAAGCCACTGCTCATCGGCTCTGTTAAAAGCAATCTGGGGCA
TCTTGAGTCAGCCGCAGGTGTCGCTGGCCTGGTTAAGGCACTGCTGTGCATCCAGAACCGTGCCATCCCTGCCACCATCG
GCATTACCCAGCTCAACCCGGCAATTCCATTTAACGATTTGAATATTGAGGTGGCTACCGATTGCAGACCCATTACCAAG
AACGGTGAGATTATTATTGGCGTCAACTCCTTTGGTTTCGGGGGGGCTAACGCCCACGTTGTACTGAAAAGTTACGAGCC
TTCAGCCAGCAGCTCAAAAAAAGTAAGCCTCCAGGTGCTCCCTCTGATACTTTCTGCTAAGAACATGGATGCCTTAAAAA
CATCAGCCAGAGACATTGCAGCATACCTGGATAGCAATCAACAGACCCCCTTGTATGACATCACCTACAACGCTCTCTTC
CGTCGAGAGTTATTTGAATACCAAAGCGTTATTTTCGGCAGCACTCACGCGGAAATAGCCAAGCAACTGCGTACATTCTT
AGATAATGAAACCATCCTGACAGGCACTCCTGTGGCAATGCCAGCAGGCCCAGTATTTGTTTACTCCGGTAATGGGGCCC
AGTGGTTCGGCATGGGCAAAGCCCTTCTGGCTGACCCACTATTTCTTAAAACTGTCCAGGAAATAGACTTCTTCTTCACT
CAGTATGCGGACTGGTCTCTTGAAAAAGAGCTGAGCGGACAGTATGGCATTGACCGCTATGCCGACACTGAAATTGCGCA
ACCGGCACTGTTTGCCATCCAGGTCGGCATAACCCGGATGCTTCACGAACGTGGTGTCAGCCCAACAGCAGTCACCGGCC
ACAGTGTTGGTGAAGTTGCAGCTGCCTGGGCATCTGGCGCCTTGTCACTGGAAGCTGCAGTGCGGGTTATCTACCATCGC
AGCAAACTCCAAGGCACGACAAAAGGCCAGGGGCAAATGAGCGCAATCGGATTAGGAGAAGCTGATGCCCAACAATTGCT
CTTCACGCTTGGGCTCGCTGACGTCCTGACGATTGCAGGCAGCAATAGCGGCAAAGGGGTTACGATCGCTGGAACGACTG
AGGGATTGAGCGCGCTTGAATCAGCCCTTGCAAACCGGAACATATTTAACAAACGCCTTGCCCTTGACTACGCCTTCCAC
AGTCCGGCAATGGACCCGCTTGAACCGGGTATTATCTCGGCACTTGCTTCGCTTGCACCGCAAACAGCGTCTGTCTCGTT
TTACTCAACAGTCACCGGAGGACAACTTAACGGAACAGCACTTGATGCTGCCTACTGGTGGCATAACCTGCGTAAACCGG
TTCAATTCGACCGCACCATCAAGCAATTGCTTGCAGACGGCTTGAACGTCTTTATCGAGATCAGCCCGAACGCGATCCTG
CGCAGCTACCTGCAGGACTGCCTGAATGAAACAGCTCTGCCGGGACGTATCATCACCACCGGCATGCGTGGCGATGATAC
CCCGCAAAGAATGACAGCTGCGGTAAGTCAAACAATCATCAGCGGCGTCCCCATTGACTGGACTGTTTTCTTCCCTGAAA
AAGCTGGCGTAGTGGAACTGCCCCATTATCCATGGCAGCGGGAACAGTACTGGCACACCGTAACACCTGAATCATATGGT
CTACTGCACCGTTACAAACTACATGCCTTTTTAGGTTACAGGCTTGCTCAGCATGAGCTTACCTGGGAAAACCAACTTGA
TACCCGGCTCATTCCCCTGCTGGCAGACCATCAGGTCGGCGATGCTGTTGTCTTTCCCGCTGCCGGTTTTGCCGAACTGA
CATTGGCCGCCTCCCACGCCTGGCAGCCTGCTGAGTACTGTGAGATCGAAGAGCTGGAAATTCATGCCCCTTTGCTCATT
AAAGATAACCATTCAAAACTGATTCGCGTAGCCGTTGATCCAGCCCGTGGCGATCTGACTATCAAAGGCAGGGAATTAAC
CAGCACTGAACCATGGGAACTGCATGTCTCAGCAAGAATCCTGCAGGGTTCTCCTGTCAGGATACACCAGGAACAGCGAA
TCACCCTGCCTGAAAGATTTCCGGATTTCTCCGGCGCAGAACATCATCAGCTTACCACAGCTGCCGGACTGGGGTATGGC
CCGGCATTTCAGGTCATTAAATCCGGTTGGATTGAAAACAACACTGTTACTGCTATCTACAAAGCCGAAGAAACACCAGA
TAACACTAACCTCTCCACCTTCCATCTGCACCCGGCCTACCTGGATTGTGCCTTCCAGTTGATCTTTCAGCTTATGCAGG
AGCAACTGTCCGAGCAGAGCGGCATTATCTTTATCCCGGTAAAAATCGGGCGGCTGTTCCTGCATGATATCCAACGCATC
CCGCAACGGGCCAGGGCGACAATGCTGCGCCGTGCTCCGCACTCGCTGACAGCGGAATTCGTCATTGCCGATGCCGAAGG
CTTACCAATCGCCATTATTCAGGAAGCTCGTTTCCGTGCTGTCCGCCTCAGTATCAAACGTACGGATGCAAGACTCAGAT
TTCTGGCCTATCACAGCATACCAAGCCCTCATCCGTTGACACCGCGCTGTGCATCACCACTACCTTTTCAACTGTTCAGG
CATGAGATGAGTGAGGCAGTAAGGCAAGCCGTGCTTAAAGGCACACATCGATGCTATTCTGAAGAGGTTGATCCGCTGCT
TGATGTACTCTGCAGCCGTTTCACCCTGGAGGCACTCCAGCCACTGGCCGATGAGGCGCAACAACTTGACAACGCAACAA
TTCAGGGATTCCACTCAAAAAATCCGGGACAGACACGCTATCTTGAACACCTGATAGATCTATTGGTTCAGGATGCCCTG
CTGACGCCAACGGAAACGGGCTTTAAGATCTCTGCCCCTGACACAAACAGTATCGCTGCGCAGGATATCTGGAACAGCCT
GTTTCACGATTACCCCGACTACTTTCCGATCCTCCATAGCGTTTCACAGGTAGGACTGCATCTACACAAGCTTTTTTCTG
AACCAGGTGCCGCAGGGTTTCTACCTGCACCCGGTTCGCTGACATCCCTTACCCGGAATCTGTTAGGGGCTGCAGCAAAA
AGCAAAATTGAAGATGCCTTGCACAAGCTGCTTGTCAATGGGCTTACCACTCTTCCCACAGGAAGCCGCCTCGGCATCAT
TGAGGTCAGCGATGGCCTGCCACTCTTTGCTTCCGCAATCTGCCAACTGCTGGATTTCGATCAGTGCAGCTATCTCTTTG
CAACTCATAACGGCGAAACCGCCGATGAAGCGCGACAACAGCTTGACCGGTTTCCAGCTGCAGAGATTCAGCTGATTGAA
CCATCAGCATCCTTTGAACAGCCTGTTGGTGGCCGGTTGTATGATCTGGCAATTATACAGTCTGACTTCCCTACCATTGA
GGCGGCTTCTGATAGTATACGTACCGCATTAACGTATCTGGCCCCGGAAGGAGTGGTGATCTTCATTGGTCACCACCCGT
CACGATGGACCGATTTTGTATTTGGCTGTCGCACCGACTGGTGGCGCGACAGCAGTTCGGCAACACCGCAATCCCAGCAG
CAACCGCCCGCTTTCTGGCAGAAACAGCTGGAACAGCAAGGTCTGACTGAACTTGAGTGCCATGAACTATCCCCCAAAGC
CTCATCGGGTCCGTATCTGTTACTTGGCCGCAAGCCTGAAGCAGCACCTGTTTCAGCCCCACCTTTGCTTATAAATACAG
AAGCTGTCTGGCTGATCCTGTCTGATGAACAAGGCGATTCAGGCCAGCTGGCGAATGAGCTTTCAAACAGGCTCAAGGAC
GCTGGAGGGCGGGCTGTCCTCTCCACACTCACTTCCAGAGAGGCCATTGCAGATCAGTTGCAGAACATAAAAAAATCATA
TGGAGTACTAACCGGAATTCTCCATCTCAGCGGCTTTCGGTCGGAACCACTTGATGATCCAATCTCGGACTTTTCCAGAG
AAACCGACCGTTGTGCCACGACAGCCGCAATTGTCGCTGCATCTGAAGCAACACAGACCAGCACCACCTGCTGGTTAATC
AGTGCCAACGCTGCCAGCTATCTGCTGCCGATACAGACAGCTGCCCGACATGCCGATAAGGTCAATTTTTCAGCCGATGC
TGCACTATGGGGATTGGGACGTACCCTGATCAATGAAATGCCCTCAGGTTCCATACGCATGGTTGACCTTGAAATGCCAG
CTGATCTTGAGACAATGGCATCTGCACTCATAAAAGAGCTTATCCAGCCGGATGACGAGCAGGAAATATGTATCAACTCT
GACGGCAGACGTTTTGCAACCCGTCTGCAACTTCTGCCTGCTTCAACAATCTTCCTCCAAGGACAGTCTCCGCAGGCTGC
TTCCCCCTGCTACCGCCTGGGCTTCCAGTTTCCCGGACAGCTACGTAACCTGCGCTGGGAGTCCTGCGTCGGTTCTGCAC
CGAAAGGCGATGAAATAGAGATAGAGGTCCATGCCACCGGCCTTAATTTCCGCGATTTCATGTACACCCTTGGCCTGCTG
TCTGATGAAGCAGTTGAAAACGGTTTTGCCGGACCAACCCTTGGTATGGAATTTTCCGGCACTGTTGTTCGTGTTGGAGA
GTCAGTGCAGGAGTTTGCCCCCGGTGACCATCTGGTGGGGTTCGGCCCGGCCTGTTTCAGCAATCGTGTCATCACCAAAT
CCAACGCGGTCTCCTTCATTCCGGCCGGTTTATCCTTTGAAGCTGCCGTAACCATCCCGGCAACCTTTTTTACCAGTTTT
TATGCACTGCATTATCTCGCCAGAGTTGCACCGGGAGAAAAAGTACTGATCCACGGGGCCGCCGGGGGTGTCGGTATTGC
CGCCATTCAGGTCGCACGATGGTGCGGAGCTGAAATCCATGCAACTGCCGGTACCGATGAAAAGCGTGACTTCCTGCGTA
TGCTTGGAATTGACTTTATCTATGATTCGCGTTCTTTGCATTTTGCTGATGAACTACTGGCCCGGACAGGTGGCAGCGGT
GTTGATGTTGTGCTGAACTCCCTTTCCGGCGAAGCGATCAATCGGAACCTGCGGATACTCAAACCGTTCGGACGGTTTCT
GGAGTTAGGCAAGCGGGACTACTACGAAAATACCCGCATCGGTCTGCGCCCCTTCAGAAACAACATCAGTTACTTTGGCA
TTGATGCCGACCAGCTGATGCAGGAACGCCCGGATCTAACCCGCACACTGTTCAAGCAGATTATGTCGCTCTTTACCGAA
GGGGTTTTCCATCCGTTGCCGTTCCAGACCTTTGATGCCAACGACATCGTAAATGCCTTCAGATACATGCAACAGTCACG
TCAAATCGGCAAGATCGTAGTCACCTATAAAAACGGGGTCACCGTCCCGGCCTGTGACGCAAAAACAGCTGCAGGCAGTC
TCGTTTTACCGCCTGACGCCACCTTTCTGATAACCGGAGGCCTGAGCGGTTTTGGACTTAAAACCGCTGAATGGCTCGTG
CAAAAAGGGGTGCGTAACCTTGTGCTTATCAGCCGAAGCGGCCCGGTTTCAGAAGAAGCCAAACAGGCAATCAGCCAACT
GCAACGATCAGGCGTTACGGTTCATGCCACTGCATGTGATACCACCGAAAAAGCTGCACTGACACAGCTGTTTGCCGAAA
TTGCTAAGACACTTCCTCCACTTACCGGGATCGTCCATGCCGCAATGGTAATCCAGGACGGCCTGATCAAGGCCATGGAC
AAACAACAGATCAGTCAGGTCCTGGCCCCCAAAATACTCGGTGCCACCTATCTACATGAACTATCGCAGCAATTGCCGAT
TAAGTACTTCATCCTTTTTTCATCGGCAACCACCCTGTTCGGCAACCCCGGGCAGGGAAACTACGTAGCGGCAAACCATT
GGCTTGAGGCATTTGCAGCCCACCGCCAGACATGCGGCCTGCCGGTCACTTGCGTAGGCTGGAGCCCTATTGATGACGCC
GGCTTCCTTGCACAGAACCAACAGATCAAGGATGCACTGCAAAGTCGCCTGGGGGGTGAAGCGATCAGTGCTTCCACAGC
CCTTGATCAGCTGGAAAAGCTGCTGTTGGCTAACCAGTCCGGCCTTGGTGTACTTGATCTGGACTGGAAAACCCTCAGCC
GCTCACTGCCAAGCGCTAACAGTCCAAAATTCATGAAACTTTCGCAACTGGCCGGCAGCAGCAGTGAACAACAGGAGCAA
AAACCGGATATACGGCAACTGTTGGCTGAACTTTCAGAAACAGAGATTCTGTCAACCTTCATGGATCTATTGAAACACGA
AGTAGGCACGGTACTCAGAATTGATCCGACTAAAATTGATCCGAACCGCCTTCTTTCCGATATGGGACTGGATTCGTTAA
TGGGGGTAGAACTGGCAGTTGCTCTGGAGTCACTATTTGGTATCAAGGTGCCGGTCATGGTACTCACTGACAGCCCAACC
ATAGCCAAACTGGCGCAGCATCTGCTTACCCAGCTTTCCTCATCCCGGGATATTGCTGAAAACAGTACGCACCAGGAAAC
TGTTGCATCGGTTCAGCAGGCGGTTTCTCAGCATGGCGCAGAGGTCACGGAGGAGATTATTGAGCAGATTGTACATGATG
TGTATGCTACTCCAGCAACGGACGAAAAAAGGATGATCCAGTAA

Upstream 100 bases:

>100_bases
TATAACAAGAGATAGCAATAATTTCTACATAGATTGAACGAGCCCGCCAAATATGCTAATATGAATATAAATAATTTACG
ACTCCTCAGTCAGGATTTAC

Downstream 100 bases:

>100_bases
TATGCCTCGTAAAGGATTGCACGGACTTACCGCCCAACTTAAAGATGCACTGATTTTGCAGGCTCTTGAGCGGCGGTTAC
AAACTGCAGAACGCCAGGAA

Product: beta-ketoacyl synthase

Products: NA

Alternate protein names: 6-deoxyerythronolide B synthase II; DEBS 2; ORF 2 [H]

Number of amino acids: Translated: 2547; Mature: 2546

Protein sequence:

>2547_residues
MPPTVAIIGFSFRLPNTTQEAFWNDLLQGRDLVTSVPNNRWSQETFYHPDKDHPGASYSFTAGPIGDVSLFDAGFFGISP
REAAVMDPQQRLLLELGWEACEHAGIKPSSLRGSRCGVYIGVSNIDYAFRLTDDLAAIDSSSGTGNTSSIAANRLSYFFD
LHGPSMAIDTACSSSLVAFHQACVSIASGESSMALAGGVSLHLHPYTFVAFSKASMLSKQGHCNVFDAACDGYVRSEGAG
LFLLKEYNQAVADGDQILAVVAASAVNTDGRKSGLTVPSAKAQSTLLKQAYLRAGIAPAEIDYIEAHGTGTTVGDPIEVQ
AIGEALGKQRPEGKPLLIGSVKSNLGHLESAAGVAGLVKALLCIQNRAIPATIGITQLNPAIPFNDLNIEVATDCRPITK
NGEIIIGVNSFGFGGANAHVVLKSYEPSASSSKKVSLQVLPLILSAKNMDALKTSARDIAAYLDSNQQTPLYDITYNALF
RRELFEYQSVIFGSTHAEIAKQLRTFLDNETILTGTPVAMPAGPVFVYSGNGAQWFGMGKALLADPLFLKTVQEIDFFFT
QYADWSLEKELSGQYGIDRYADTEIAQPALFAIQVGITRMLHERGVSPTAVTGHSVGEVAAAWASGALSLEAAVRVIYHR
SKLQGTTKGQGQMSAIGLGEADAQQLLFTLGLADVLTIAGSNSGKGVTIAGTTEGLSALESALANRNIFNKRLALDYAFH
SPAMDPLEPGIISALASLAPQTASVSFYSTVTGGQLNGTALDAAYWWHNLRKPVQFDRTIKQLLADGLNVFIEISPNAIL
RSYLQDCLNETALPGRIITTGMRGDDTPQRMTAAVSQTIISGVPIDWTVFFPEKAGVVELPHYPWQREQYWHTVTPESYG
LLHRYKLHAFLGYRLAQHELTWENQLDTRLIPLLADHQVGDAVVFPAAGFAELTLAASHAWQPAEYCEIEELEIHAPLLI
KDNHSKLIRVAVDPARGDLTIKGRELTSTEPWELHVSARILQGSPVRIHQEQRITLPERFPDFSGAEHHQLTTAAGLGYG
PAFQVIKSGWIENNTVTAIYKAEETPDNTNLSTFHLHPAYLDCAFQLIFQLMQEQLSEQSGIIFIPVKIGRLFLHDIQRI
PQRARATMLRRAPHSLTAEFVIADAEGLPIAIIQEARFRAVRLSIKRTDARLRFLAYHSIPSPHPLTPRCASPLPFQLFR
HEMSEAVRQAVLKGTHRCYSEEVDPLLDVLCSRFTLEALQPLADEAQQLDNATIQGFHSKNPGQTRYLEHLIDLLVQDAL
LTPTETGFKISAPDTNSIAAQDIWNSLFHDYPDYFPILHSVSQVGLHLHKLFSEPGAAGFLPAPGSLTSLTRNLLGAAAK
SKIEDALHKLLVNGLTTLPTGSRLGIIEVSDGLPLFASAICQLLDFDQCSYLFATHNGETADEARQQLDRFPAAEIQLIE
PSASFEQPVGGRLYDLAIIQSDFPTIEAASDSIRTALTYLAPEGVVIFIGHHPSRWTDFVFGCRTDWWRDSSSATPQSQQ
QPPAFWQKQLEQQGLTELECHELSPKASSGPYLLLGRKPEAAPVSAPPLLINTEAVWLILSDEQGDSGQLANELSNRLKD
AGGRAVLSTLTSREAIADQLQNIKKSYGVLTGILHLSGFRSEPLDDPISDFSRETDRCATTAAIVAASEATQTSTTCWLI
SANAASYLLPIQTAARHADKVNFSADAALWGLGRTLINEMPSGSIRMVDLEMPADLETMASALIKELIQPDDEQEICINS
DGRRFATRLQLLPASTIFLQGQSPQAASPCYRLGFQFPGQLRNLRWESCVGSAPKGDEIEIEVHATGLNFRDFMYTLGLL
SDEAVENGFAGPTLGMEFSGTVVRVGESVQEFAPGDHLVGFGPACFSNRVITKSNAVSFIPAGLSFEAAVTIPATFFTSF
YALHYLARVAPGEKVLIHGAAGGVGIAAIQVARWCGAEIHATAGTDEKRDFLRMLGIDFIYDSRSLHFADELLARTGGSG
VDVVLNSLSGEAINRNLRILKPFGRFLELGKRDYYENTRIGLRPFRNNISYFGIDADQLMQERPDLTRTLFKQIMSLFTE
GVFHPLPFQTFDANDIVNAFRYMQQSRQIGKIVVTYKNGVTVPACDAKTAAGSLVLPPDATFLITGGLSGFGLKTAEWLV
QKGVRNLVLISRSGPVSEEAKQAISQLQRSGVTVHATACDTTEKAALTQLFAEIAKTLPPLTGIVHAAMVIQDGLIKAMD
KQQISQVLAPKILGATYLHELSQQLPIKYFILFSSATTLFGNPGQGNYVAANHWLEAFAAHRQTCGLPVTCVGWSPIDDA
GFLAQNQQIKDALQSRLGGEAISASTALDQLEKLLLANQSGLGVLDLDWKTLSRSLPSANSPKFMKLSQLAGSSSEQQEQ
KPDIRQLLAELSETEILSTFMDLLKHEVGTVLRIDPTKIDPNRLLSDMGLDSLMGVELAVALESLFGIKVPVMVLTDSPT
IAKLAQHLLTQLSSSRDIAENSTHQETVASVQQAVSQHGAEVTEEIIEQIVHDVYATPATDEKRMIQ

Sequences:

>Translated_2547_residues
MPPTVAIIGFSFRLPNTTQEAFWNDLLQGRDLVTSVPNNRWSQETFYHPDKDHPGASYSFTAGPIGDVSLFDAGFFGISP
REAAVMDPQQRLLLELGWEACEHAGIKPSSLRGSRCGVYIGVSNIDYAFRLTDDLAAIDSSSGTGNTSSIAANRLSYFFD
LHGPSMAIDTACSSSLVAFHQACVSIASGESSMALAGGVSLHLHPYTFVAFSKASMLSKQGHCNVFDAACDGYVRSEGAG
LFLLKEYNQAVADGDQILAVVAASAVNTDGRKSGLTVPSAKAQSTLLKQAYLRAGIAPAEIDYIEAHGTGTTVGDPIEVQ
AIGEALGKQRPEGKPLLIGSVKSNLGHLESAAGVAGLVKALLCIQNRAIPATIGITQLNPAIPFNDLNIEVATDCRPITK
NGEIIIGVNSFGFGGANAHVVLKSYEPSASSSKKVSLQVLPLILSAKNMDALKTSARDIAAYLDSNQQTPLYDITYNALF
RRELFEYQSVIFGSTHAEIAKQLRTFLDNETILTGTPVAMPAGPVFVYSGNGAQWFGMGKALLADPLFLKTVQEIDFFFT
QYADWSLEKELSGQYGIDRYADTEIAQPALFAIQVGITRMLHERGVSPTAVTGHSVGEVAAAWASGALSLEAAVRVIYHR
SKLQGTTKGQGQMSAIGLGEADAQQLLFTLGLADVLTIAGSNSGKGVTIAGTTEGLSALESALANRNIFNKRLALDYAFH
SPAMDPLEPGIISALASLAPQTASVSFYSTVTGGQLNGTALDAAYWWHNLRKPVQFDRTIKQLLADGLNVFIEISPNAIL
RSYLQDCLNETALPGRIITTGMRGDDTPQRMTAAVSQTIISGVPIDWTVFFPEKAGVVELPHYPWQREQYWHTVTPESYG
LLHRYKLHAFLGYRLAQHELTWENQLDTRLIPLLADHQVGDAVVFPAAGFAELTLAASHAWQPAEYCEIEELEIHAPLLI
KDNHSKLIRVAVDPARGDLTIKGRELTSTEPWELHVSARILQGSPVRIHQEQRITLPERFPDFSGAEHHQLTTAAGLGYG
PAFQVIKSGWIENNTVTAIYKAEETPDNTNLSTFHLHPAYLDCAFQLIFQLMQEQLSEQSGIIFIPVKIGRLFLHDIQRI
PQRARATMLRRAPHSLTAEFVIADAEGLPIAIIQEARFRAVRLSIKRTDARLRFLAYHSIPSPHPLTPRCASPLPFQLFR
HEMSEAVRQAVLKGTHRCYSEEVDPLLDVLCSRFTLEALQPLADEAQQLDNATIQGFHSKNPGQTRYLEHLIDLLVQDAL
LTPTETGFKISAPDTNSIAAQDIWNSLFHDYPDYFPILHSVSQVGLHLHKLFSEPGAAGFLPAPGSLTSLTRNLLGAAAK
SKIEDALHKLLVNGLTTLPTGSRLGIIEVSDGLPLFASAICQLLDFDQCSYLFATHNGETADEARQQLDRFPAAEIQLIE
PSASFEQPVGGRLYDLAIIQSDFPTIEAASDSIRTALTYLAPEGVVIFIGHHPSRWTDFVFGCRTDWWRDSSSATPQSQQ
QPPAFWQKQLEQQGLTELECHELSPKASSGPYLLLGRKPEAAPVSAPPLLINTEAVWLILSDEQGDSGQLANELSNRLKD
AGGRAVLSTLTSREAIADQLQNIKKSYGVLTGILHLSGFRSEPLDDPISDFSRETDRCATTAAIVAASEATQTSTTCWLI
SANAASYLLPIQTAARHADKVNFSADAALWGLGRTLINEMPSGSIRMVDLEMPADLETMASALIKELIQPDDEQEICINS
DGRRFATRLQLLPASTIFLQGQSPQAASPCYRLGFQFPGQLRNLRWESCVGSAPKGDEIEIEVHATGLNFRDFMYTLGLL
SDEAVENGFAGPTLGMEFSGTVVRVGESVQEFAPGDHLVGFGPACFSNRVITKSNAVSFIPAGLSFEAAVTIPATFFTSF
YALHYLARVAPGEKVLIHGAAGGVGIAAIQVARWCGAEIHATAGTDEKRDFLRMLGIDFIYDSRSLHFADELLARTGGSG
VDVVLNSLSGEAINRNLRILKPFGRFLELGKRDYYENTRIGLRPFRNNISYFGIDADQLMQERPDLTRTLFKQIMSLFTE
GVFHPLPFQTFDANDIVNAFRYMQQSRQIGKIVVTYKNGVTVPACDAKTAAGSLVLPPDATFLITGGLSGFGLKTAEWLV
QKGVRNLVLISRSGPVSEEAKQAISQLQRSGVTVHATACDTTEKAALTQLFAEIAKTLPPLTGIVHAAMVIQDGLIKAMD
KQQISQVLAPKILGATYLHELSQQLPIKYFILFSSATTLFGNPGQGNYVAANHWLEAFAAHRQTCGLPVTCVGWSPIDDA
GFLAQNQQIKDALQSRLGGEAISASTALDQLEKLLLANQSGLGVLDLDWKTLSRSLPSANSPKFMKLSQLAGSSSEQQEQ
KPDIRQLLAELSETEILSTFMDLLKHEVGTVLRIDPTKIDPNRLLSDMGLDSLMGVELAVALESLFGIKVPVMVLTDSPT
IAKLAQHLLTQLSSSRDIAENSTHQETVASVQQAVSQHGAEVTEEIIEQIVHDVYATPATDEKRMIQ
>Mature_2546_residues
PPTVAIIGFSFRLPNTTQEAFWNDLLQGRDLVTSVPNNRWSQETFYHPDKDHPGASYSFTAGPIGDVSLFDAGFFGISPR
EAAVMDPQQRLLLELGWEACEHAGIKPSSLRGSRCGVYIGVSNIDYAFRLTDDLAAIDSSSGTGNTSSIAANRLSYFFDL
HGPSMAIDTACSSSLVAFHQACVSIASGESSMALAGGVSLHLHPYTFVAFSKASMLSKQGHCNVFDAACDGYVRSEGAGL
FLLKEYNQAVADGDQILAVVAASAVNTDGRKSGLTVPSAKAQSTLLKQAYLRAGIAPAEIDYIEAHGTGTTVGDPIEVQA
IGEALGKQRPEGKPLLIGSVKSNLGHLESAAGVAGLVKALLCIQNRAIPATIGITQLNPAIPFNDLNIEVATDCRPITKN
GEIIIGVNSFGFGGANAHVVLKSYEPSASSSKKVSLQVLPLILSAKNMDALKTSARDIAAYLDSNQQTPLYDITYNALFR
RELFEYQSVIFGSTHAEIAKQLRTFLDNETILTGTPVAMPAGPVFVYSGNGAQWFGMGKALLADPLFLKTVQEIDFFFTQ
YADWSLEKELSGQYGIDRYADTEIAQPALFAIQVGITRMLHERGVSPTAVTGHSVGEVAAAWASGALSLEAAVRVIYHRS
KLQGTTKGQGQMSAIGLGEADAQQLLFTLGLADVLTIAGSNSGKGVTIAGTTEGLSALESALANRNIFNKRLALDYAFHS
PAMDPLEPGIISALASLAPQTASVSFYSTVTGGQLNGTALDAAYWWHNLRKPVQFDRTIKQLLADGLNVFIEISPNAILR
SYLQDCLNETALPGRIITTGMRGDDTPQRMTAAVSQTIISGVPIDWTVFFPEKAGVVELPHYPWQREQYWHTVTPESYGL
LHRYKLHAFLGYRLAQHELTWENQLDTRLIPLLADHQVGDAVVFPAAGFAELTLAASHAWQPAEYCEIEELEIHAPLLIK
DNHSKLIRVAVDPARGDLTIKGRELTSTEPWELHVSARILQGSPVRIHQEQRITLPERFPDFSGAEHHQLTTAAGLGYGP
AFQVIKSGWIENNTVTAIYKAEETPDNTNLSTFHLHPAYLDCAFQLIFQLMQEQLSEQSGIIFIPVKIGRLFLHDIQRIP
QRARATMLRRAPHSLTAEFVIADAEGLPIAIIQEARFRAVRLSIKRTDARLRFLAYHSIPSPHPLTPRCASPLPFQLFRH
EMSEAVRQAVLKGTHRCYSEEVDPLLDVLCSRFTLEALQPLADEAQQLDNATIQGFHSKNPGQTRYLEHLIDLLVQDALL
TPTETGFKISAPDTNSIAAQDIWNSLFHDYPDYFPILHSVSQVGLHLHKLFSEPGAAGFLPAPGSLTSLTRNLLGAAAKS
KIEDALHKLLVNGLTTLPTGSRLGIIEVSDGLPLFASAICQLLDFDQCSYLFATHNGETADEARQQLDRFPAAEIQLIEP
SASFEQPVGGRLYDLAIIQSDFPTIEAASDSIRTALTYLAPEGVVIFIGHHPSRWTDFVFGCRTDWWRDSSSATPQSQQQ
PPAFWQKQLEQQGLTELECHELSPKASSGPYLLLGRKPEAAPVSAPPLLINTEAVWLILSDEQGDSGQLANELSNRLKDA
GGRAVLSTLTSREAIADQLQNIKKSYGVLTGILHLSGFRSEPLDDPISDFSRETDRCATTAAIVAASEATQTSTTCWLIS
ANAASYLLPIQTAARHADKVNFSADAALWGLGRTLINEMPSGSIRMVDLEMPADLETMASALIKELIQPDDEQEICINSD
GRRFATRLQLLPASTIFLQGQSPQAASPCYRLGFQFPGQLRNLRWESCVGSAPKGDEIEIEVHATGLNFRDFMYTLGLLS
DEAVENGFAGPTLGMEFSGTVVRVGESVQEFAPGDHLVGFGPACFSNRVITKSNAVSFIPAGLSFEAAVTIPATFFTSFY
ALHYLARVAPGEKVLIHGAAGGVGIAAIQVARWCGAEIHATAGTDEKRDFLRMLGIDFIYDSRSLHFADELLARTGGSGV
DVVLNSLSGEAINRNLRILKPFGRFLELGKRDYYENTRIGLRPFRNNISYFGIDADQLMQERPDLTRTLFKQIMSLFTEG
VFHPLPFQTFDANDIVNAFRYMQQSRQIGKIVVTYKNGVTVPACDAKTAAGSLVLPPDATFLITGGLSGFGLKTAEWLVQ
KGVRNLVLISRSGPVSEEAKQAISQLQRSGVTVHATACDTTEKAALTQLFAEIAKTLPPLTGIVHAAMVIQDGLIKAMDK
QQISQVLAPKILGATYLHELSQQLPIKYFILFSSATTLFGNPGQGNYVAANHWLEAFAAHRQTCGLPVTCVGWSPIDDAG
FLAQNQQIKDALQSRLGGEAISASTALDQLEKLLLANQSGLGVLDLDWKTLSRSLPSANSPKFMKLSQLAGSSSEQQEQK
PDIRQLLAELSETEILSTFMDLLKHEVGTVLRIDPTKIDPNRLLSDMGLDSLMGVELAVALESLFGIKVPVMVLTDSPTI
AKLAQHLLTQLSSSRDIAENSTHQETVASVQQAVSQHGAEVTEEIIEQIVHDVYATPATDEKRMIQ

Specific function: Catalyzes The Condensation Reaction Of Fatty Acid Synthesis By The Addition To An Acyl Acceptor Of Two Carbons From Malonyl-Acp. Has A Preference For Short Chain Acid Substrates And May Function To Supply The Octanoic Substrates For Lipoic Acid Biosynthe

COG id: COG3321

COG function: function code Q; Polyketide synthase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI41872631, Length=1104, Percent_Identity=30.2536231884058, Blast_Score=380, Evalue=1e-104,
Organism=Homo sapiens, GI8923559, Length=281, Percent_Identity=30.6049822064057, Blast_Score=112, Evalue=5e-24,
Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=29.0909090909091, Blast_Score=111, Evalue=8e-24,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=29.0909090909091, Blast_Score=111, Evalue=8e-24,
Organism=Homo sapiens, GI18379349, Length=319, Percent_Identity=25.3918495297806, Blast_Score=111, Evalue=9e-24,
Organism=Homo sapiens, GI194239674, Length=249, Percent_Identity=29.3172690763052, Blast_Score=108, Evalue=7e-23,
Organism=Homo sapiens, GI13236495, Length=249, Percent_Identity=29.3172690763052, Blast_Score=108, Evalue=7e-23,
Organism=Homo sapiens, GI24308257, Length=340, Percent_Identity=26.1764705882353, Blast_Score=99, Evalue=7e-20,
Organism=Homo sapiens, GI194239676, Length=201, Percent_Identity=30.3482587064677, Blast_Score=88, Evalue=1e-16,
Organism=Homo sapiens, GI239744023, Length=103, Percent_Identity=40.7766990291262, Blast_Score=85, Evalue=1e-15,
Organism=Homo sapiens, GI310129082, Length=103, Percent_Identity=40.7766990291262, Blast_Score=84, Evalue=2e-15,
Organism=Homo sapiens, GI310109937, Length=103, Percent_Identity=40.7766990291262, Blast_Score=84, Evalue=2e-15,
Organism=Homo sapiens, GI197927207, Length=116, Percent_Identity=35.3448275862069, Blast_Score=78, Evalue=1e-13,
Organism=Homo sapiens, GI47519420, Length=340, Percent_Identity=24.4117647058824, Blast_Score=73, Evalue=4e-12,
Organism=Homo sapiens, GI28557745, Length=330, Percent_Identity=24.2424242424242, Blast_Score=72, Evalue=6e-12,
Organism=Homo sapiens, GI90669511, Length=170, Percent_Identity=32.9411764705882, Blast_Score=72, Evalue=6e-12,
Organism=Homo sapiens, GI226059159, Length=218, Percent_Identity=24.3119266055046, Blast_Score=71, Evalue=2e-11,
Organism=Homo sapiens, GI226059133, Length=218, Percent_Identity=24.3119266055046, Blast_Score=71, Evalue=2e-11,
Organism=Homo sapiens, GI226056130, Length=139, Percent_Identity=29.4964028776978, Blast_Score=70, Evalue=2e-11,
Organism=Escherichia coli, GI1787337, Length=281, Percent_Identity=31.6725978647687, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI1788663, Length=271, Percent_Identity=30.6273062730627, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1790485, Length=221, Percent_Identity=31.2217194570136, Blast_Score=94, Evalue=1e-19,
Organism=Escherichia coli, GI1787334, Length=298, Percent_Identity=26.1744966442953, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI212642053, Length=917, Percent_Identity=32.824427480916, Blast_Score=396, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17550940, Length=813, Percent_Identity=26.8142681426814, Blast_Score=247, Evalue=7e-65,
Organism=Caenorhabditis elegans, GI71983541, Length=282, Percent_Identity=28.7234042553192, Blast_Score=115, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71983535, Length=269, Percent_Identity=29.7397769516729, Blast_Score=112, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17507255, Length=178, Percent_Identity=30.8988764044944, Blast_Score=82, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320904, Length=283, Percent_Identity=27.208480565371, Blast_Score=111, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319520, Length=218, Percent_Identity=28.8990825688073, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI221330659, Length=997, Percent_Identity=31.2938816449348, Blast_Score=397, Evalue=1e-110,
Organism=Drosophila melanogaster, GI19920632, Length=1158, Percent_Identity=29.6200345423143, Blast_Score=396, Evalue=1e-110,
Organism=Drosophila melanogaster, GI24581345, Length=997, Percent_Identity=30.1905717151454, Blast_Score=352, Evalue=2e-96,
Organism=Drosophila melanogaster, GI24644341, Length=286, Percent_Identity=32.5174825174825, Blast_Score=124, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR002198
- InterPro:   IPR015357
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR020806
- InterPro:   IPR015083
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00106 adh_short; PF00107 ADH_zinc_N; PF08990 Docking; PF09277 Erythro-docking; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF00550 PP-binding [H]

EC number: =2.3.1.94 [H]

Molecular weight: Translated: 276839; Mature: 276708

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS01162 QOR_ZETA_CRYSTAL ; PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPTVAIIGFSFRLPNTTQEAFWNDLLQGRDLVTSVPNNRWSQETFYHPDKDHPGASYSF
CCCCEEEEEEEEECCCCHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCEEE
TAGPIGDVSLFDAGFFGISPREAAVMDPQQRLLLELGWEACEHAGIKPSSLRGSRCGVYI
CCCCCCCCHHCCCCCCCCCCCCHHHCCHHHHHHHHHCHHHHHHCCCCCCCCCCCCCEEEE
GVSNIDYAFRLTDDLAAIDSSSGTGNTSSIAANRLSYFFDLHGPSMAIDTACSSSLVAFH
EECCCCEEEEECHHHHHHCCCCCCCCCHHHHHHHHEEEEEECCCCEEHHHHHHHHHHHHH
QACVSIASGESSMALAGGVSLHLHPYTFVAFSKASMLSKQGHCNVFDAACDGYVRSEGAG
HHHHHHHCCCCCEEEECCCEEEECCEEEEEEHHHHHHHCCCCCCEEHHHCCCCEECCCCC
LFLLKEYNQAVADGDQILAVVAASAVNTDGRKSGLTVPSAKAQSTLLKQAYLRAGIAPAE
EEEEEHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
IDYIEAHGTGTTVGDPIEVQAIGEALGKQRPEGKPLLIGSVKSNLGHLESAAGVAGLVKA
EEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHH
LLCIQNRAIPATIGITQLNPAIPFNDLNIEVATDCRPITKNGEIIIGVNSFGFGGANAHV
HHHHCCCCCEEEEEEEECCCCCCCCCCCEEEECCCEECCCCCCEEEEECCCCCCCCCEEE
VLKSYEPSASSSKKVSLQVLPLILSAKNMDALKTSARDIAAYLDSNQQTPLYDITYNALF
EEEECCCCCCCCCEEEEEEEEHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHH
RRELFEYQSVIFGSTHAEIAKQLRTFLDNETILTGTPVAMPAGPVFVYSGNGAQWFGMGK
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEECCCCEEECCCH
ALLADPLFLKTVQEIDFFFTQYADWSLEKELSGQYGIDRYADTEIAQPALFAIQVGITRM
HHHHCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCHHCCHHHHHHHHHHHHH
LHERGVSPTAVTGHSVGEVAAAWASGALSLEAAVRVIYHRSKLQGTTKGQGQMSAIGLGE
HHHCCCCCCEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCC
ADAQQLLFTLGLADVLTIAGSNSGKGVTIAGTTEGLSALESALANRNIFNKRLALDYAFH
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHCCCHHHHHHEEEEEEC
SPAMDPLEPGIISALASLAPQTASVSFYSTVTGGQLNGTALDAAYWWHNLRKPVQFDRTI
CCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHH
KQLLADGLNVFIEISPNAILRSYLQDCLNETALPGRIITTGMRGDDTPQRMTAAVSQTII
HHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
SGVPIDWTVFFPEKAGVVELPHYPWQREQYWHTVTPESYGLLHRYKLHAFLGYRLAQHEL
CCCCCEEEEEECCCCCEEECCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCC
TWENQLDTRLIPLLADHQVGDAVVFPAAGFAELTLAASHAWQPAEYCEIEELEIHAPLLI
CCCCCCCCCHHHHEECCCCCCEEEECCCCHHHHHHHHHCCCCCHHHCCCEEEEECCCEEE
KDNHSKLIRVAVDPARGDLTIKGRELTSTEPWELHVSARILQGSPVRIHQEQRITLPERF
ECCCCEEEEEEECCCCCCEEEECCCCCCCCCEEEEEEEEEECCCCEEEECCCCCCCHHHC
PDFSGAEHHQLTTAAGLGYGPAFQVIKSGWIENNTVTAIYKAEETPDNTNLSTFHLHPAY
CCCCCCCCCEEEHHHCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEEECHHH
LDCAFQLIFQLMQEQLSEQSGIIFIPVKIGRLFLHDIQRIPQRARATMLRRAPHSLTAEF
HHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
VIADAEGLPIAIIQEARFRAVRLSIKRTDARLRFLAYHSIPSPHPLTPRCASPLPFQLFR
EEECCCCCCEEEEHHHHHEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHH
HEMSEAVRQAVLKGTHRCYSEEVDPLLDVLCSRFTLEALQPLADEAQQLDNATIQGFHSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCC
NPGQTRYLEHLIDLLVQDALLTPTETGFKISAPDTNSIAAQDIWNSLFHDYPDYFPILHS
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHH
VSQVGLHLHKLFSEPGAAGFLPAPGSLTSLTRNLLGAAAKSKIEDALHKLLVNGLTTLPT
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GSRLGIIEVSDGLPLFASAICQLLDFDQCSYLFATHNGETADEARQQLDRFPAAEIQLIE
CCCEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEC
PSASFEQPVGGRLYDLAIIQSDFPTIEAASDSIRTALTYLAPEGVVIFIGHHPSRWTDFV
CCCCCCCCCCCCEEEEEEEECCCCCCHHCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHH
FGCRTDWWRDSSSATPQSQQQPPAFWQKQLEQQGLTELECHELSPKASSGPYLLLGRKPE
HCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEHHHCCCCCCCCCCEEEEECCCC
AAPVSAPPLLINTEAVWLILSDEQGDSGQLANELSNRLKDAGGRAVLSTLTSREAIADQL
CCCCCCCCEEEECCEEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
QNIKKSYGVLTGILHLSGFRSEPLDDPISDFSRETDRCATTAAIVAASEATQTSTTCWLI
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEE
SANAASYLLPIQTAARHADKVNFSADAALWGLGRTLINEMPSGSIRMVDLEMPADLETMA
ECCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHH
SALIKELIQPDDEQEICINSDGRRFATRLQLLPASTIFLQGQSPQAASPCYRLGFQFPGQ
HHHHHHHHCCCCCCCEEECCCCHHHHHHHHHCCCEEEEEECCCCCCCCCHHHCCCCCCHH
LRNLRWESCVGSAPKGDEIEIEVHATGLNFRDFMYTLGLLSDEAVENGFAGPTLGMEFSG
HHCCCHHHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCC
TVVRVGESVQEFAPGDHLVGFGPACFSNRVITKSNAVSFIPAGLSFEAAVTIPATFFTSF
CEEEECHHHHHHCCCCCEEECCHHHHCCCEEECCCCCEEEECCCCEEEEEECHHHHHHHH
YALHYLARVAPGEKVLIHGAAGGVGIAAIQVARWCGAEIHATAGTDEKRDFLRMLGIDFI
HHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHCCCEE
YDSRSLHFADELLARTGGSGVDVVLNSLSGEAINRNLRILKPFGRFLELGKRDYYENTRI
ECCCCHHHHHHHHHHCCCCCHHHHHHHCCCHHHCCCCEEEHHHHHHHHHCCHHCCCCCCC
GLRPFRNNISYFGIDADQLMQERPDLTRTLFKQIMSLFTEGVFHPLPFQTFDANDIVNAF
CCEEHHCCCCEEECCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
RYMQQSRQIGKIVVTYKNGVTVPACDAKTAAGSLVLPPDATFLITGGLSGFGLKTAEWLV
HHHHHHHCCCEEEEEECCCCEECCCCCCCCCCCEEECCCCCEEEECCCCCCCCHHHHHHH
QKGVRNLVLISRSGPVSEEAKQAISQLQRSGVTVHATACDTTEKAALTQLFAEIAKTLPP
HHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCC
LTGIVHAAMVIQDGLIKAMDKQQISQVLAPKILGATYLHELSQQLPIKYFILFSSATTLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHCC
GNPGQGNYVAANHWLEAFAAHRQTCGLPVTCVGWSPIDDAGFLAQNQQIKDALQSRLGGE
CCCCCCCEEEHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHCCHHHHHHHHHHCCCC
AISASTALDQLEKLLLANQSGLGVLDLDWKTLSRSLPSANSPKFMKLSQLAGSSSEQQEQ
HHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHCCCCCCCCCCEEHHHHCCCCCHHHHC
KPDIRQLLAELSETEILSTFMDLLKHEVGTVLRIDPTKIDPNRLLSDMGLDSLMGVELAV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHCCHHHHHHHHHHH
ALESLFGIKVPVMVLTDSPTIAKLAQHLLTQLSSSRDIAENSTHQETVASVQQAVSQHGA
HHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHCCH
EVTEEIIEQIVHDVYATPATDEKRMIQ
HHHHHHHHHHHHHHHCCCCCCCHHCCC
>Mature Secondary Structure 
PPTVAIIGFSFRLPNTTQEAFWNDLLQGRDLVTSVPNNRWSQETFYHPDKDHPGASYSF
CCCEEEEEEEEECCCCHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCEEE
TAGPIGDVSLFDAGFFGISPREAAVMDPQQRLLLELGWEACEHAGIKPSSLRGSRCGVYI
CCCCCCCCHHCCCCCCCCCCCCHHHCCHHHHHHHHHCHHHHHHCCCCCCCCCCCCCEEEE
GVSNIDYAFRLTDDLAAIDSSSGTGNTSSIAANRLSYFFDLHGPSMAIDTACSSSLVAFH
EECCCCEEEEECHHHHHHCCCCCCCCCHHHHHHHHEEEEEECCCCEEHHHHHHHHHHHHH
QACVSIASGESSMALAGGVSLHLHPYTFVAFSKASMLSKQGHCNVFDAACDGYVRSEGAG
HHHHHHHCCCCCEEEECCCEEEECCEEEEEEHHHHHHHCCCCCCEEHHHCCCCEECCCCC
LFLLKEYNQAVADGDQILAVVAASAVNTDGRKSGLTVPSAKAQSTLLKQAYLRAGIAPAE
EEEEEHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
IDYIEAHGTGTTVGDPIEVQAIGEALGKQRPEGKPLLIGSVKSNLGHLESAAGVAGLVKA
EEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHH
LLCIQNRAIPATIGITQLNPAIPFNDLNIEVATDCRPITKNGEIIIGVNSFGFGGANAHV
HHHHCCCCCEEEEEEEECCCCCCCCCCCEEEECCCEECCCCCCEEEEECCCCCCCCCEEE
VLKSYEPSASSSKKVSLQVLPLILSAKNMDALKTSARDIAAYLDSNQQTPLYDITYNALF
EEEECCCCCCCCCEEEEEEEEHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHH
RRELFEYQSVIFGSTHAEIAKQLRTFLDNETILTGTPVAMPAGPVFVYSGNGAQWFGMGK
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEECCCCEEECCCH
ALLADPLFLKTVQEIDFFFTQYADWSLEKELSGQYGIDRYADTEIAQPALFAIQVGITRM
HHHHCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCHHCCHHHHHHHHHHHHH
LHERGVSPTAVTGHSVGEVAAAWASGALSLEAAVRVIYHRSKLQGTTKGQGQMSAIGLGE
HHHCCCCCCEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCC
ADAQQLLFTLGLADVLTIAGSNSGKGVTIAGTTEGLSALESALANRNIFNKRLALDYAFH
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHCCCHHHHHHEEEEEEC
SPAMDPLEPGIISALASLAPQTASVSFYSTVTGGQLNGTALDAAYWWHNLRKPVQFDRTI
CCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHH
KQLLADGLNVFIEISPNAILRSYLQDCLNETALPGRIITTGMRGDDTPQRMTAAVSQTII
HHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
SGVPIDWTVFFPEKAGVVELPHYPWQREQYWHTVTPESYGLLHRYKLHAFLGYRLAQHEL
CCCCCEEEEEECCCCCEEECCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCC
TWENQLDTRLIPLLADHQVGDAVVFPAAGFAELTLAASHAWQPAEYCEIEELEIHAPLLI
CCCCCCCCCHHHHEECCCCCCEEEECCCCHHHHHHHHHCCCCCHHHCCCEEEEECCCEEE
KDNHSKLIRVAVDPARGDLTIKGRELTSTEPWELHVSARILQGSPVRIHQEQRITLPERF
ECCCCEEEEEEECCCCCCEEEECCCCCCCCCEEEEEEEEEECCCCEEEECCCCCCCHHHC
PDFSGAEHHQLTTAAGLGYGPAFQVIKSGWIENNTVTAIYKAEETPDNTNLSTFHLHPAY
CCCCCCCCCEEEHHHCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEEECHHH
LDCAFQLIFQLMQEQLSEQSGIIFIPVKIGRLFLHDIQRIPQRARATMLRRAPHSLTAEF
HHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
VIADAEGLPIAIIQEARFRAVRLSIKRTDARLRFLAYHSIPSPHPLTPRCASPLPFQLFR
EEECCCCCCEEEEHHHHHEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHH
HEMSEAVRQAVLKGTHRCYSEEVDPLLDVLCSRFTLEALQPLADEAQQLDNATIQGFHSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCC
NPGQTRYLEHLIDLLVQDALLTPTETGFKISAPDTNSIAAQDIWNSLFHDYPDYFPILHS
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHH
VSQVGLHLHKLFSEPGAAGFLPAPGSLTSLTRNLLGAAAKSKIEDALHKLLVNGLTTLPT
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GSRLGIIEVSDGLPLFASAICQLLDFDQCSYLFATHNGETADEARQQLDRFPAAEIQLIE
CCCEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEC
PSASFEQPVGGRLYDLAIIQSDFPTIEAASDSIRTALTYLAPEGVVIFIGHHPSRWTDFV
CCCCCCCCCCCCEEEEEEEECCCCCCHHCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHH
FGCRTDWWRDSSSATPQSQQQPPAFWQKQLEQQGLTELECHELSPKASSGPYLLLGRKPE
HCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEHHHCCCCCCCCCCEEEEECCCC
AAPVSAPPLLINTEAVWLILSDEQGDSGQLANELSNRLKDAGGRAVLSTLTSREAIADQL
CCCCCCCCEEEECCEEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
QNIKKSYGVLTGILHLSGFRSEPLDDPISDFSRETDRCATTAAIVAASEATQTSTTCWLI
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEE
SANAASYLLPIQTAARHADKVNFSADAALWGLGRTLINEMPSGSIRMVDLEMPADLETMA
ECCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHH
SALIKELIQPDDEQEICINSDGRRFATRLQLLPASTIFLQGQSPQAASPCYRLGFQFPGQ
HHHHHHHHCCCCCCCEEECCCCHHHHHHHHHCCCEEEEEECCCCCCCCCHHHCCCCCCHH
LRNLRWESCVGSAPKGDEIEIEVHATGLNFRDFMYTLGLLSDEAVENGFAGPTLGMEFSG
HHCCCHHHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCC
TVVRVGESVQEFAPGDHLVGFGPACFSNRVITKSNAVSFIPAGLSFEAAVTIPATFFTSF
CEEEECHHHHHHCCCCCEEECCHHHHCCCEEECCCCCEEEECCCCEEEEEECHHHHHHHH
YALHYLARVAPGEKVLIHGAAGGVGIAAIQVARWCGAEIHATAGTDEKRDFLRMLGIDFI
HHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHCCCEE
YDSRSLHFADELLARTGGSGVDVVLNSLSGEAINRNLRILKPFGRFLELGKRDYYENTRI
ECCCCHHHHHHHHHHCCCCCHHHHHHHCCCHHHCCCCEEEHHHHHHHHHCCHHCCCCCCC
GLRPFRNNISYFGIDADQLMQERPDLTRTLFKQIMSLFTEGVFHPLPFQTFDANDIVNAF
CCEEHHCCCCEEECCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
RYMQQSRQIGKIVVTYKNGVTVPACDAKTAAGSLVLPPDATFLITGGLSGFGLKTAEWLV
HHHHHHHCCCEEEEEECCCCEECCCCCCCCCCCEEECCCCCEEEECCCCCCCCHHHHHHH
QKGVRNLVLISRSGPVSEEAKQAISQLQRSGVTVHATACDTTEKAALTQLFAEIAKTLPP
HHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCC
LTGIVHAAMVIQDGLIKAMDKQQISQVLAPKILGATYLHELSQQLPIKYFILFSSATTLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHCC
GNPGQGNYVAANHWLEAFAAHRQTCGLPVTCVGWSPIDDAGFLAQNQQIKDALQSRLGGE
CCCCCCCEEEHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHCCHHHHHHHHHHCCCC
AISASTALDQLEKLLLANQSGLGVLDLDWKTLSRSLPSANSPKFMKLSQLAGSSSEQQEQ
HHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHCCCCCCCCCCEEHHHHCCCCCHHHHC
KPDIRQLLAELSETEILSTFMDLLKHEVGTVLRIDPTKIDPNRLLSDMGLDSLMGVELAV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHCCHHHHHHHHHHH
ALESLFGIKVPVMVLTDSPTIAKLAQHLLTQLSSSRDIAENSTHQETVASVQQAVSQHGA
HHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHCCH
EVTEEIIEQIVHDVYATPATDEKRMIQ
HHHHHHHHHHHHHHHCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2024119; 1740151 [H]