Click here to switch to the map view.

The map label for this gene is pepQ [H]

Identifier: 189424444

GI number: 189424444

Start: 1416535

End: 1417725

Strand: Reverse

Name: pepQ [H]

Synonym: Glov_1380

Alternate gene names: 189424444

Gene position: 1417725-1416535 (Counterclockwise)

Preceding gene: 189424446

Following gene: 189424443

Centisome position: 36.19

GC content: 53.57

Gene sequence:

>1191_bases
ATGCGACTAACCCCGGCCACTGAACTTGAATACCGCTGCAAGAAACTGCAGGCTCTGATGCAAACTGCTGACCTTGACGC
GGTGCTGATTGTGCAGAACGCAGACCTTTATTACTTTACCGGCACCGTTCAGAACGGCTGCCTGTATGTCCCAGCCCAGG
GGCAGCCGCTCTATCTGGTTCGCCGGGATCAGGCCCGGGCGCGGATGGAATCGGGGCTGAAAGAGGTACTGTCTTTTTCT
GCCCCGAGGGATATACCAGCCATAATCAGCAGTTATGGATACCCGGAGCCCAAAAGGATCGGACTTGAATTTGACGTACT
GCCGGTTGTCTTTCTGGAGCGTTATCGCAAGGTCTGGCCCAATGTGGTTTTCAGCGATGCAACACCCCTGATCCGTCAGG
TACGGATGATCAAGAGTCACTATGAGATTCACCTGATGCAGGATGCTGCAGACCAGGTACACAAGATCTATGAACGGGCC
AAAGAAGTCATCAAGGTAGGAATGACTGATATCGAGCTGGCAGCAGAACTGGAATACACCGCACGGAAACATGGCCATCT
GGGGTTGATCAGGATGCGGGTTTTCAATGGCGAAATGTTTTTCGGCCATACCTTCTCAGGCACTGACAGTGCTGTCCCGG
CCTACACCGATACCCCCTTCGGCGGCCTGGGAGCCTCTCCCTGTTTTGGGCAGGGAGCCGGTCACAAACCGATTGGCCCC
AATGAGCCGATTATCATGGACTTTGCCGGCAGCATTGACGGTTACCTGGTGGATCAGACCCGCATCTTCAGTATCGGCCC
ATTGTCTGCCCGGCTTACGCAAGGTTTTGAAGATATGCTGAAGGTGCAGGAGCTTATGAAAGAGATTGCAGTGCCTGGCA
TCAGTTGGGGCGAAATCTACGACCGCTGTCACGGGCTTGCCATGGAGCTGGGCTATGCCGACAGTTTCATGGGGGCTCCC
AGCTCACAGGTTTCCTTCATCGGTCATGGCCTGGGTATTGAGATTGATGAGTACCCGTTTATTGCAAAAGGTTTCAAGGA
TCAGGTCATGGAAATTGGTATGGCCTGGGCCTTTGAACCCAAGGTGGTCTTCCCCGGCGAAGGAGCCGTCGGCATTGAAA
ACACCTTCTACCTCAGCAACGATGGACTGAAGCAGCTGACCAGATCTGACGACGCACTAGTAATTTTATAA

Upstream 100 bases:

>100_bases
GGCCAATTGAAAATGAGGTAAAGATTCGTCCAGACATGGTGCGGCACCCTAGCCGGTTCCAGCCTCGCCGTCAAGTACCA
GAAGAAAGGATTAACCAACC

Downstream 100 bases:

>100_bases
TGTTGTTTCAGTATACAAAAAACCTGTTGTATTTGGCCCCACAGGGTGTTATAACAGCCAAAATTTTTGTATACAGTATA
TTCAAAACGTTTATTGTATT

Product: creatinase

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MRLTPATELEYRCKKLQALMQTADLDAVLIVQNADLYYFTGTVQNGCLYVPAQGQPLYLVRRDQARARMESGLKEVLSFS
APRDIPAIISSYGYPEPKRIGLEFDVLPVVFLERYRKVWPNVVFSDATPLIRQVRMIKSHYEIHLMQDAADQVHKIYERA
KEVIKVGMTDIELAAELEYTARKHGHLGLIRMRVFNGEMFFGHTFSGTDSAVPAYTDTPFGGLGASPCFGQGAGHKPIGP
NEPIIMDFAGSIDGYLVDQTRIFSIGPLSARLTQGFEDMLKVQELMKEIAVPGISWGEIYDRCHGLAMELGYADSFMGAP
SSQVSFIGHGLGIEIDEYPFIAKGFKDQVMEIGMAWAFEPKVVFPGEGAVGIENTFYLSNDGLKQLTRSDDALVIL

Sequences:

>Translated_396_residues
MRLTPATELEYRCKKLQALMQTADLDAVLIVQNADLYYFTGTVQNGCLYVPAQGQPLYLVRRDQARARMESGLKEVLSFS
APRDIPAIISSYGYPEPKRIGLEFDVLPVVFLERYRKVWPNVVFSDATPLIRQVRMIKSHYEIHLMQDAADQVHKIYERA
KEVIKVGMTDIELAAELEYTARKHGHLGLIRMRVFNGEMFFGHTFSGTDSAVPAYTDTPFGGLGASPCFGQGAGHKPIGP
NEPIIMDFAGSIDGYLVDQTRIFSIGPLSARLTQGFEDMLKVQELMKEIAVPGISWGEIYDRCHGLAMELGYADSFMGAP
SSQVSFIGHGLGIEIDEYPFIAKGFKDQVMEIGMAWAFEPKVVFPGEGAVGIENTFYLSNDGLKQLTRSDDALVIL
>Mature_396_residues
MRLTPATELEYRCKKLQALMQTADLDAVLIVQNADLYYFTGTVQNGCLYVPAQGQPLYLVRRDQARARMESGLKEVLSFS
APRDIPAIISSYGYPEPKRIGLEFDVLPVVFLERYRKVWPNVVFSDATPLIRQVRMIKSHYEIHLMQDAADQVHKIYERA
KEVIKVGMTDIELAAELEYTARKHGHLGLIRMRVFNGEMFFGHTFSGTDSAVPAYTDTPFGGLGASPCFGQGAGHKPIGP
NEPIIMDFAGSIDGYLVDQTRIFSIGPLSARLTQGFEDMLKVQELMKEIAVPGISWGEIYDRCHGLAMELGYADSFMGAP
SSQVSFIGHGLGIEIDEYPFIAKGFKDQVMEIGMAWAFEPKVVFPGEGAVGIENTFYLSNDGLKQLTRSDDALVIL

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788728, Length=273, Percent_Identity=26.007326007326, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 44027; Mature: 44027

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTPATELEYRCKKLQALMQTADLDAVLIVQNADLYYFTGTVQNGCLYVPAQGQPLYLV
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEECCCCEEEEECCCCEEEEE
RRDQARARMESGLKEVLSFSAPRDIPAIISSYGYPEPKRIGLEFDVLPVVFLERYRKVWP
ECHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHCCCEECHHHHHHHHHHHHHCC
NVVFSDATPLIRQVRMIKSHYEIHLMQDAADQVHKIYERAKEVIKVGMTDIELAAELEYT
CEEECCCHHHHHHHHHHHHHCEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ARKHGHLGLIRMRVFNGEMFFGHTFSGTDSAVPAYTDTPFGGLGASPCFGQGAGHKPIGP
HHCCCCEEEEEEEEECCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NEPIIMDFAGSIDGYLVDQTRIFSIGPLSARLTQGFEDMLKVQELMKEIAVPGISWGEIY
CCCEEEEECCCCCCEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
DRCHGLAMELGYADSFMGAPSSQVSFIGHGLGIEIDEYPFIAKGFKDQVMEIGMAWAFEP
HHHHHHHEECCCCHHHCCCCCCCCEEEECCCCCEECCCCCHHCCHHHHHHHHHHHEEECC
KVVFPGEGAVGIENTFYLSNDGLKQLTRSDDALVIL
EEEECCCCCCCCCEEEEECCCCHHHHHCCCCCEEEC
>Mature Secondary Structure
MRLTPATELEYRCKKLQALMQTADLDAVLIVQNADLYYFTGTVQNGCLYVPAQGQPLYLV
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEECCCCEEEEECCCCEEEEE
RRDQARARMESGLKEVLSFSAPRDIPAIISSYGYPEPKRIGLEFDVLPVVFLERYRKVWP
ECHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHCCCEECHHHHHHHHHHHHHCC
NVVFSDATPLIRQVRMIKSHYEIHLMQDAADQVHKIYERAKEVIKVGMTDIELAAELEYT
CEEECCCHHHHHHHHHHHHHCEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ARKHGHLGLIRMRVFNGEMFFGHTFSGTDSAVPAYTDTPFGGLGASPCFGQGAGHKPIGP
HHCCCCEEEEEEEEECCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NEPIIMDFAGSIDGYLVDQTRIFSIGPLSARLTQGFEDMLKVQELMKEIAVPGISWGEIY
CCCEEEEECCCCCCEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
DRCHGLAMELGYADSFMGAPSSQVSFIGHGLGIEIDEYPFIAKGFKDQVMEIGMAWAFEP
HHHHHHHEECCCCHHHCCCCCCCCEEEECCCCCEECCCCCHHCCHHHHHHHHHHHEEECC
KVVFPGEGAVGIENTFYLSNDGLKQLTRSDDALVIL
EEEECCCCCCCCCEEEEECCCCHHHHHCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]