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The map label for this gene is zraR [H]

Identifier: 189424231

GI number: 189424231

Start: 1219947

End: 1221290

Strand: Reverse

Name: zraR [H]

Synonym: Glov_1166

Alternate gene names: 189424231

Gene position: 1221290-1219947 (Counterclockwise)

Preceding gene: 189424232

Following gene: 189424230

Centisome position: 31.17

GC content: 54.39

Gene sequence:

>1344_bases
ATGCCTGATCCACTTATTCTCATTGTCGATGATGACCTGAGGATGCGGCAACTGATCAGGGATACTCTGGCAAGTGAGGG
TATCAATGCAGTCCTCTGCAGTGACGGCGCTGAGGCTGCAGAAATGGTGTTACGCCAAACAACAGATCTGATCATCACTG
ATTTGATGATGCCACAGATAGACGGCATGGAACTGCTGAACCTGGCCCTTCAGGCTAACCCTGACTGCCTGGTGGTGGTG
ATTACCGGATACGGTTCAATTGAGTCGGCAGTACAGGCAATTAAAAACGGCGCCTACGACTATCTGCAGAAACCGTTTGA
GCCGGATCAACTGTTGCTGGTGGTGCAACGGGCACTGGTACGGTTGCGTCTACAGGATGAAAATCGCCAGCTACGCCAGC
AGGTAGCCGGATGCCAAGCCGACGAGCTTCTGGGCGCCAGCAAACAGATGACTACACTGAAGGCGCTGATCACCAGGATC
GCACCTTTTGATACCACGGTCCTTATTCAGGGGGAAACCGGAACCGGCAAGGAGTTGGCGGCACGAATGATTCACCGCCT
GAGCCAGCGTCGTGACCAGCGTTTCCTGCCGATCAACTGTGGCGCCCTGCCTGAAACACTGCTGGAATCAGAGCTGTTTG
GCCATGCCCGCGGTGCCTTTACCGGTGCTGACAAAGACAAGAAAGGGCTGCTGGAATCTGCAGACCATGGCACCCTGTTT
CTGGATGAAATCAACACCACCTCTCCAGCCTTTCAGGTCAAGTTACTGAGGGTTTTGCAGGAAGGGAGCTTCATCAGGGT
TGGTGACCACGAACCGCGCTCGGTTGACCTGCGGGTGATCGCCGCCAGCAACACAACGCTTGAAAAGGAGGTCCAGACAG
GGAGATTTCGCAGTGATCTGTTTTATCGCCTGAACGTGGTCACGATTACACTGCCGCCGCTTCGTGAACGCAATGGTGAC
ATCGGCCTGTTGGCCCACTACTTTCTGACCCGCTACGCCAGGCAATACGGAGTGCAGCTGTCCAGCATCTCTCCAGAGGC
GTTGCAGAGTCTGCGCAACTATCATTGGCCCGGCAATGTGCGTGAACTGGAAAACATCATTGAACGGGCTGTGATTATGG
CTGATGGAAACGAACTGCAGCCGCAGTACCTGCCGCGCTTTTCTGTATCCGACACCCCGCTTTCATCCTCATCCGACCAG
GAACTGCTTCCAATGGCTGAAGTGGAACGACGGCATATCATCCGCGTACTCAAAGCCACCGCAGGGCATCGGGGCAAGGC
CTCAAAACTGCTTGGCATCAGTCTTGCCTCACTTTGGAGAAAAGTAAAACAGTACGGATTGTAA

Upstream 100 bases:

>100_bases
GCAGGAATTGTGAATGAGAACGGCGGCAATATCGATATTGTCAAGTCAGACAGCAGAGGCACGACCTTTGTTGTAATCCT
GCCCTGCAAGGAGTCGGTCG

Downstream 100 bases:

>100_bases
GTCAGCCCACCCCCATTAACCCCCTCTCATTTCATTCAATCTGCACGATCGTTTCATTTTGAAACAACCATATGCCGCCA
CATTTCAATAATTTAAGTGT

Product: Fis family two component sigma-54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MPDPLILIVDDDLRMRQLIRDTLASEGINAVLCSDGAEAAEMVLRQTTDLIITDLMMPQIDGMELLNLALQANPDCLVVV
ITGYGSIESAVQAIKNGAYDYLQKPFEPDQLLLVVQRALVRLRLQDENRQLRQQVAGCQADELLGASKQMTTLKALITRI
APFDTTVLIQGETGTGKELAARMIHRLSQRRDQRFLPINCGALPETLLESELFGHARGAFTGADKDKKGLLESADHGTLF
LDEINTTSPAFQVKLLRVLQEGSFIRVGDHEPRSVDLRVIAASNTTLEKEVQTGRFRSDLFYRLNVVTITLPPLRERNGD
IGLLAHYFLTRYARQYGVQLSSISPEALQSLRNYHWPGNVRELENIIERAVIMADGNELQPQYLPRFSVSDTPLSSSSDQ
ELLPMAEVERRHIIRVLKATAGHRGKASKLLGISLASLWRKVKQYGL

Sequences:

>Translated_447_residues
MPDPLILIVDDDLRMRQLIRDTLASEGINAVLCSDGAEAAEMVLRQTTDLIITDLMMPQIDGMELLNLALQANPDCLVVV
ITGYGSIESAVQAIKNGAYDYLQKPFEPDQLLLVVQRALVRLRLQDENRQLRQQVAGCQADELLGASKQMTTLKALITRI
APFDTTVLIQGETGTGKELAARMIHRLSQRRDQRFLPINCGALPETLLESELFGHARGAFTGADKDKKGLLESADHGTLF
LDEINTTSPAFQVKLLRVLQEGSFIRVGDHEPRSVDLRVIAASNTTLEKEVQTGRFRSDLFYRLNVVTITLPPLRERNGD
IGLLAHYFLTRYARQYGVQLSSISPEALQSLRNYHWPGNVRELENIIERAVIMADGNELQPQYLPRFSVSDTPLSSSSDQ
ELLPMAEVERRHIIRVLKATAGHRGKASKLLGISLASLWRKVKQYGL
>Mature_446_residues
PDPLILIVDDDLRMRQLIRDTLASEGINAVLCSDGAEAAEMVLRQTTDLIITDLMMPQIDGMELLNLALQANPDCLVVVI
TGYGSIESAVQAIKNGAYDYLQKPFEPDQLLLVVQRALVRLRLQDENRQLRQQVAGCQADELLGASKQMTTLKALITRIA
PFDTTVLIQGETGTGKELAARMIHRLSQRRDQRFLPINCGALPETLLESELFGHARGAFTGADKDKKGLLESADHGTLFL
DEINTTSPAFQVKLLRVLQEGSFIRVGDHEPRSVDLRVIAASNTTLEKEVQTGRFRSDLFYRLNVVTITLPPLRERNGDI
GLLAHYFLTRYARQYGVQLSSISPEALQSLRNYHWPGNVRELENIIERAVIMADGNELQPQYLPRFSVSDTPLSSSSDQE
LLPMAEVERRHIIRVLKATAGHRGKASKLLGISLASLWRKVKQYGL

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=441, Percent_Identity=42.4036281179138, Blast_Score=349, Evalue=3e-97,
Organism=Escherichia coli, GI1788550, Length=452, Percent_Identity=40.929203539823, Blast_Score=338, Evalue=4e-94,
Organism=Escherichia coli, GI1790299, Length=467, Percent_Identity=39.8286937901499, Blast_Score=330, Evalue=1e-91,
Organism=Escherichia coli, GI1788905, Length=447, Percent_Identity=36.241610738255, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI87082117, Length=340, Percent_Identity=46.7647058823529, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI1789087, Length=331, Percent_Identity=46.8277945619335, Blast_Score=262, Evalue=4e-71,
Organism=Escherichia coli, GI1789233, Length=321, Percent_Identity=42.9906542056075, Blast_Score=261, Evalue=7e-71,
Organism=Escherichia coli, GI87082152, Length=320, Percent_Identity=45.625, Blast_Score=238, Evalue=4e-64,
Organism=Escherichia coli, GI1786524, Length=316, Percent_Identity=42.4050632911392, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI87081872, Length=255, Percent_Identity=45.0980392156863, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1787583, Length=358, Percent_Identity=37.7094972067039, Blast_Score=208, Evalue=6e-55,
Organism=Escherichia coli, GI87081858, Length=289, Percent_Identity=34.2560553633218, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1789828, Length=216, Percent_Identity=37.962962962963, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1789809, Length=152, Percent_Identity=29.6052631578947, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786784, Length=116, Percent_Identity=31.0344827586207, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790863, Length=121, Percent_Identity=29.7520661157025, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 49873; Mature: 49742

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDPLILIVDDDLRMRQLIRDTLASEGINAVLCSDGAEAAEMVLRQTTDLIITDLMMPQI
CCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCC
DGMELLNLALQANPDCLVVVITGYGSIESAVQAIKNGAYDYLQKPFEPDQLLLVVQRALV
CCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHH
RLRLQDENRQLRQQVAGCQADELLGASKQMTTLKALITRIAPFDTTVLIQGETGTGKELA
HHHHCCHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHH
ARMIHRLSQRRDQRFLPINCGALPETLLESELFGHARGAFTGADKDKKGLLESADHGTLF
HHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCEEE
LDEINTTSPAFQVKLLRVLQEGSFIRVGDHEPRSVDLRVIAASNTTLEKEVQTGRFRSDL
EECCCCCCHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEEEECCCCHHHHHHHCCHHHHH
FYRLNVVTITLPPLRERNGDIGLLAHYFLTRYARQYGVQLSSISPEALQSLRNYHWPGNV
EEEEEEEEEEECCHHHCCCCCHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHCCCCCCH
RELENIIERAVIMADGNELQPQYLPRFSVSDTPLSSSSDQELLPMAEVERRHIIRVLKAT
HHHHHHHHHHEEEECCCCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
AGHRGKASKLLGISLASLWRKVKQYGL
CCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PDPLILIVDDDLRMRQLIRDTLASEGINAVLCSDGAEAAEMVLRQTTDLIITDLMMPQI
CCCEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCC
DGMELLNLALQANPDCLVVVITGYGSIESAVQAIKNGAYDYLQKPFEPDQLLLVVQRALV
CCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHH
RLRLQDENRQLRQQVAGCQADELLGASKQMTTLKALITRIAPFDTTVLIQGETGTGKELA
HHHHCCHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHH
ARMIHRLSQRRDQRFLPINCGALPETLLESELFGHARGAFTGADKDKKGLLESADHGTLF
HHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCEEE
LDEINTTSPAFQVKLLRVLQEGSFIRVGDHEPRSVDLRVIAASNTTLEKEVQTGRFRSDL
EECCCCCCHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEEEECCCCHHHHHHHCCHHHHH
FYRLNVVTITLPPLRERNGDIGLLAHYFLTRYARQYGVQLSSISPEALQSLRNYHWPGNV
EEEEEEEEEEECCHHHCCCCCHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHCCCCCCH
RELENIIERAVIMADGNELQPQYLPRFSVSDTPLSSSSDQELLPMAEVERRHIIRVLKAT
HHHHHHHHHHEEEECCCCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
AGHRGKASKLLGISLASLWRKVKQYGL
CCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]