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The map label for this gene is atoC [H]

Identifier: 189424216

GI number: 189424216

Start: 1203447

End: 1204853

Strand: Reverse

Name: atoC [H]

Synonym: Glov_1151

Alternate gene names: 189424216

Gene position: 1204853-1203447 (Counterclockwise)

Preceding gene: 189424217

Following gene: 189424215

Centisome position: 30.75

GC content: 56.57

Gene sequence:

>1407_bases
ATGAACTCCTTTAAACTCCTGCTCGTTGAAGACGATCCATTGCTCGGTGAAGCCCTGTATGAGGCTTTGCATGGCAAAGG
ATTCAAGGTACGGCTGGCAAAAAGCGGTGCCGAGGCATTGGGTGCGGCCAGTGACGAATCCTTTGATCTGTTGTTGCAGG
ATGTCAGACTGCCCGATGTTGACGGTCTTGACCTGCTGGCTGATCTGCTACAGTTACAACCTACCGTACACGCTCTGGTC
ATGACCGGCCAGGCCACGGTGGAGATGGCAGTACGGGCAATGAAACTGGGGGCCTTTGACTTTATTACCAAGCCGTTTTC
CGTGGATGTCCTGATGCTGAAGCTTGAACGTCTGCTGGAGTATCGTGGGCTGGAAAAACAACTGGAGGCGTTGTCTGAAG
ACACCGCAACCAGCAGAACCATCATTACCCGTTCACCGGCCATGCGTACCATACTGGACACCATGACCATTGTTGCCGCC
AGCGAGGTGCCCCTGCTGCTGCAGGGAGAAACCGGTACCGGCAGAAAGCTTTTGGCTGAGACCATCCACAGCATGAGCAG
CAGAAAGGACAAGCCTTTTATCAGGGTAAACTGCCTGGCGCTGCCGACCCAGCTGATTGAGGCAGAGCTGTTTGGCGTTG
AAAAGGGGGCCCTGCCGGGAGCAGACCGGGCCAGGGCAGGACTGTTGGAAAAGGCGACCGGAGGCACCCTCTTTCTTGAG
GAGATTGCCGAGCTGCCGCTCAACATCCAGGCAGGTCTGGTCAAGCGGCTTGAAGAGCAATCCACCACCAGAATCGGCGG
CAGTAGCCAACATCCCCTCGATATCCGCCTGATCTGTGCCACCAGGCACGACCTGAAGCTGCTGGCCGCCGATGGCCGCT
TCCGTAGGGATCTCCTCTACCGGATCAACATCGTTACCTTGCCGATACCGCCCCTGCGGGAGCGTCGTGAAGATATCCCC
CTGCTGGCCTCCCACTTTGTTGAACGTTTTGCCCCCACACGAGAACAGCAGATCCGGCTCACCCCCGGCCTGCTTGACGC
CCTGCTCCTGCGTCCCTGGAGCGGCAACCTGCAGGAGTTGAGCAACCTGATCGAACAGCTCACCGTCCTGTATCCCGGTC
AACGGATACGGGAACACCAGCTCCCTCCCCTTGAAGATGCCCCGCTGCATATTGGTAGCCAGTTTGAAAAGATTCAGGTT
GGAATCCCGTTGCGTGATGCGGTCGCAGATTTTGAAAGACGTTATATCCTGCGTGTACTTGAGAGCCTGGGTGGCCAAAA
GGGCCGGGCTGCCGAAGTGCTGGGAATATCCCGCAAGGTACTCTGGGAAAAACTGAAGCGACAGGAACCGGAACACAGTG
AAGATACGGCCAAAACCGATTGTTACGACATCGTAACAGACCATTGA

Upstream 100 bases:

>100_bases
AGCATTGTTGAAATGCATGGCGGCACGATCACCTTCAGCAGCCGTCCGGGGAAAACCGTGTTTACGGTCAGCCTTCCCTT
GACACCGACGGAGAACGGCA

Downstream 100 bases:

>100_bases
ACCCAAAGCACTATCCTCAAAAAGCTGCAAAGGCTTGTTGTACCTGCATCCAGCATGACCCATTAAAGAGATTTAATTCT
ATAAACAGCTCCATCAACAA

Product: Fis family two component sigma-54 specific transcriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MNSFKLLLVEDDPLLGEALYEALHGKGFKVRLAKSGAEALGAASDESFDLLLQDVRLPDVDGLDLLADLLQLQPTVHALV
MTGQATVEMAVRAMKLGAFDFITKPFSVDVLMLKLERLLEYRGLEKQLEALSEDTATSRTIITRSPAMRTILDTMTIVAA
SEVPLLLQGETGTGRKLLAETIHSMSSRKDKPFIRVNCLALPTQLIEAELFGVEKGALPGADRARAGLLEKATGGTLFLE
EIAELPLNIQAGLVKRLEEQSTTRIGGSSQHPLDIRLICATRHDLKLLAADGRFRRDLLYRINIVTLPIPPLRERREDIP
LLASHFVERFAPTREQQIRLTPGLLDALLLRPWSGNLQELSNLIEQLTVLYPGQRIREHQLPPLEDAPLHIGSQFEKIQV
GIPLRDAVADFERRYILRVLESLGGQKGRAAEVLGISRKVLWEKLKRQEPEHSEDTAKTDCYDIVTDH

Sequences:

>Translated_468_residues
MNSFKLLLVEDDPLLGEALYEALHGKGFKVRLAKSGAEALGAASDESFDLLLQDVRLPDVDGLDLLADLLQLQPTVHALV
MTGQATVEMAVRAMKLGAFDFITKPFSVDVLMLKLERLLEYRGLEKQLEALSEDTATSRTIITRSPAMRTILDTMTIVAA
SEVPLLLQGETGTGRKLLAETIHSMSSRKDKPFIRVNCLALPTQLIEAELFGVEKGALPGADRARAGLLEKATGGTLFLE
EIAELPLNIQAGLVKRLEEQSTTRIGGSSQHPLDIRLICATRHDLKLLAADGRFRRDLLYRINIVTLPIPPLRERREDIP
LLASHFVERFAPTREQQIRLTPGLLDALLLRPWSGNLQELSNLIEQLTVLYPGQRIREHQLPPLEDAPLHIGSQFEKIQV
GIPLRDAVADFERRYILRVLESLGGQKGRAAEVLGISRKVLWEKLKRQEPEHSEDTAKTDCYDIVTDH
>Mature_468_residues
MNSFKLLLVEDDPLLGEALYEALHGKGFKVRLAKSGAEALGAASDESFDLLLQDVRLPDVDGLDLLADLLQLQPTVHALV
MTGQATVEMAVRAMKLGAFDFITKPFSVDVLMLKLERLLEYRGLEKQLEALSEDTATSRTIITRSPAMRTILDTMTIVAA
SEVPLLLQGETGTGRKLLAETIHSMSSRKDKPFIRVNCLALPTQLIEAELFGVEKGALPGADRARAGLLEKATGGTLFLE
EIAELPLNIQAGLVKRLEEQSTTRIGGSSQHPLDIRLICATRHDLKLLAADGRFRRDLLYRINIVTLPIPPLRERREDIP
LLASHFVERFAPTREQQIRLTPGLLDALLLRPWSGNLQELSNLIEQLTVLYPGQRIREHQLPPLEDAPLHIGSQFEKIQV
GIPLRDAVADFERRYILRVLESLGGQKGRAAEVLGISRKVLWEKLKRQEPEHSEDTAKTDCYDIVTDH

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=449, Percent_Identity=40.7572383073497, Blast_Score=329, Evalue=2e-91,
Organism=Escherichia coli, GI1788550, Length=447, Percent_Identity=40.2684563758389, Blast_Score=328, Evalue=5e-91,
Organism=Escherichia coli, GI1788905, Length=448, Percent_Identity=36.8303571428571, Blast_Score=277, Evalue=1e-75,
Organism=Escherichia coli, GI1790299, Length=460, Percent_Identity=35.6521739130435, Blast_Score=272, Evalue=4e-74,
Organism=Escherichia coli, GI87082117, Length=320, Percent_Identity=40.625, Blast_Score=218, Evalue=6e-58,
Organism=Escherichia coli, GI1789233, Length=313, Percent_Identity=38.3386581469649, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1789087, Length=316, Percent_Identity=38.6075949367089, Blast_Score=197, Evalue=9e-52,
Organism=Escherichia coli, GI1786524, Length=325, Percent_Identity=37.8461538461538, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI87081872, Length=310, Percent_Identity=35.4838709677419, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI87082152, Length=239, Percent_Identity=40.5857740585774, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1787583, Length=327, Percent_Identity=32.4159021406728, Blast_Score=165, Evalue=7e-42,
Organism=Escherichia coli, GI1789828, Length=246, Percent_Identity=36.9918699186992, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI87081858, Length=306, Percent_Identity=30.718954248366, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1786784, Length=203, Percent_Identity=32.0197044334975, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787229, Length=131, Percent_Identity=29.0076335877863, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 52099; Mature: 52099

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50045 SIGMA54_INTERACT_4 ; PS50007 PIPLC_X_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSFKLLLVEDDPLLGEALYEALHGKGFKVRLAKSGAEALGAASDESFDLLLQDVRLPDV
CCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCHHHHCCCCCCHHHHHHHHCCCCCC
DGLDLLADLLQLQPTVHALVMTGQATVEMAVRAMKLGAFDFITKPFSVDVLMLKLERLLE
CCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHH
YRGLEKQLEALSEDTATSRTIITRSPAMRTILDTMTIVAASEVPLLLQGETGTGRKLLAE
HCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHH
TIHSMSSRKDKPFIRVNCLALPTQLIEAELFGVEKGALPGADRARAGLLEKATGGTLFLE
HHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHHH
EIAELPLNIQAGLVKRLEEQSTTRIGGSSQHPLDIRLICATRHDLKLLAADGRFRRDLLY
HHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCEEEEECCCCHHHHHEE
RINIVTLPIPPLRERREDIPLLASHFVERFAPTREQQIRLTPGLLDALLLRPWSGNLQEL
EEEEEEECCCCHHHHHCCCCHHHHHHHHHHCCCCCCEEEECHHHHHHHHHCCCCCCHHHH
SNLIEQLTVLYPGQRIREHQLPPLEDAPLHIGSQFEKIQVGIPLRDAVADFERRYILRVL
HHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
ESLGGQKGRAAEVLGISRKVLWEKLKRQEPEHSEDTAKTDCYDIVTDH
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCC
>Mature Secondary Structure
MNSFKLLLVEDDPLLGEALYEALHGKGFKVRLAKSGAEALGAASDESFDLLLQDVRLPDV
CCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCHHHHCCCCCCHHHHHHHHCCCCCC
DGLDLLADLLQLQPTVHALVMTGQATVEMAVRAMKLGAFDFITKPFSVDVLMLKLERLLE
CCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHH
YRGLEKQLEALSEDTATSRTIITRSPAMRTILDTMTIVAASEVPLLLQGETGTGRKLLAE
HCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHH
TIHSMSSRKDKPFIRVNCLALPTQLIEAELFGVEKGALPGADRARAGLLEKATGGTLFLE
HHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHHH
EIAELPLNIQAGLVKRLEEQSTTRIGGSSQHPLDIRLICATRHDLKLLAADGRFRRDLLY
HHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCEEEEECCCCHHHHHEE
RINIVTLPIPPLRERREDIPLLASHFVERFAPTREQQIRLTPGLLDALLLRPWSGNLQEL
EEEEEEECCCCHHHHHCCCCHHHHHHHHHHCCCCCCEEEECHHHHHHHHHCCCCCCHHHH
SNLIEQLTVLYPGQRIREHQLPPLEDAPLHIGSQFEKIQVGIPLRDAVADFERRYILRVL
HHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
ESLGGQKGRAAEVLGISRKVLWEKLKRQEPEHSEDTAKTDCYDIVTDH
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]