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The map label for this gene is atoS [H]

Identifier: 189424217

GI number: 189424217

Start: 1204840

End: 1206315

Strand: Reverse

Name: atoS [H]

Synonym: Glov_1152

Alternate gene names: 189424217

Gene position: 1206315-1204840 (Counterclockwise)

Preceding gene: 189424218

Following gene: 189424216

Centisome position: 30.79

GC content: 56.23

Gene sequence:

>1476_bases
ATGACCCGCCGCTTTATCAGCATCAAGACGCAGTTTGTGCTGATTGCCATGCTGATGGTGGCACTGTCGTCAACACTGTG
GGGCGTTTTTGCCTGGAAGACCGAACGAAATCTGCTGTACAGCAACCTGGAAAATGAAGGGCGCCAGATGCTGACCTCCC
TTTCCTCGCCGATCATTAATGCCCTGGTGTACGAAGAAATGGGAGTGATTGAGGAAGGTGGCCTGCTGGACAATTTTATT
GAAGAGATCATGAAGAACAGCACTCTCAAGGTGGTCTCTGCCTTCGTGACCGATCAGAACGGCAAAGTCCTGGCCCACAA
CCAGTATACCGAGTACGGCAAGCAGTACGATGATCTCCTGACCCGCACCGCTATCACGGAAGGACGTTACCAGGCCTCGC
TGCAAAAACAGCCGGGACAGTCCGGTACCCTGCTGAATATGGCCATGCCGTTGCATATCTACCAAAAAAGCTGGGGGGCC
CTGCGGGTTGTGGTCTCCACCGCCCCGCTTGAGGCACAGCTCCAGGGGCTGGCCAAACGTATCGCAGCAACCTCGCTGGC
TTTTTTTCTGTTGGGAATGGCAGCCTCGTACCTGATCGGACGCAGCATGGCCCGCCCCCTGCAGCGGCTGTCCGAGATAA
TGGCCTCAGTATCCACCGACAACCTGCTGGTTGAACTCCCCCCTGATCGCCCCGATGAAATCGGCAAACTGCAGGAAAGC
TTCCGTACCATGCTCGAACGTCTGCGGCAGAGTGAAGCTGAACGGAAACGTGCCGTAACACAATTGGTCCAGAGTGAAAA
ACTGGCCTCATTGGGCAAGATCGTGGCCGGTGTGGCCCATGAAGTAAACAACCCGCTGGGAGCGATCAACGCCTCCATCT
ACAACCTGGAGCAGAAAAGCGGCAACCAGCTGCGTAACATGGAAATAATCAAACAGGGCGTGGAGCGGATTGAGCGGATC
GTACGCCAGCTGAGCGACTTCAGCCGCACCGCCTCGCTGGAGTTACAGCCCCTTGCCAGTGAGGGTTTCTTCAGCGAGTG
TGCCGAATTCAGCCGTGTGGCGCTCAAGCGCTTTGATGTAGAGCTTGTGACTGAAGACCGCTGCGCCCCAGCGCTCATGC
TGCAGCTGGACAAAGGCAAGATCCAGCAGGTGCTGCTTAATCTGCTGTTCAATGCTGCCCAGGCTTCACCCCTCAGAGGG
ATAATCCGCTTATCAGCGCAACTCACCCCCGGCTACTACCAGCTTGAGGTCGAGGATCAGGGGAGCGGCATCCCGCCGGA
AGCACAACGGACGGTGTTTGACATCTTTTATACCACCAAGCATGCTGGCGAAGGGACCGGCATCGGGCTTGCCATCTGCA
AAAGCATTGTTGAAATGCATGGCGGCACGATCACCTTCAGCAGCCGTCCGGGGAAAACCGTGTTTACGGTCAGCCTTCCC
TTGACACCGACGGAGAACGGCAATGAACTCCTTTAA

Upstream 100 bases:

>100_bases
TCAACAACGGTTTTGCCACAGCCCGTCAGCAGGATTATGCCGACATCTTCCGTATGATCCGTGCCATACCAACCGGCTGC
GGCATCGGATGCCACCACAA

Downstream 100 bases:

>100_bases
ACTCCTGCTCGTTGAAGACGATCCATTGCTCGGTGAAGCCCTGTATGAGGCTTTGCATGGCAAAGGATTCAAGGTACGGC
TGGCAAAAAGCGGTGCCGAG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MTRRFISIKTQFVLIAMLMVALSSTLWGVFAWKTERNLLYSNLENEGRQMLTSLSSPIINALVYEEMGVIEEGGLLDNFI
EEIMKNSTLKVVSAFVTDQNGKVLAHNQYTEYGKQYDDLLTRTAITEGRYQASLQKQPGQSGTLLNMAMPLHIYQKSWGA
LRVVVSTAPLEAQLQGLAKRIAATSLAFFLLGMAASYLIGRSMARPLQRLSEIMASVSTDNLLVELPPDRPDEIGKLQES
FRTMLERLRQSEAERKRAVTQLVQSEKLASLGKIVAGVAHEVNNPLGAINASIYNLEQKSGNQLRNMEIIKQGVERIERI
VRQLSDFSRTASLELQPLASEGFFSECAEFSRVALKRFDVELVTEDRCAPALMLQLDKGKIQQVLLNLLFNAAQASPLRG
IIRLSAQLTPGYYQLEVEDQGSGIPPEAQRTVFDIFYTTKHAGEGTGIGLAICKSIVEMHGGTITFSSRPGKTVFTVSLP
LTPTENGNELL

Sequences:

>Translated_491_residues
MTRRFISIKTQFVLIAMLMVALSSTLWGVFAWKTERNLLYSNLENEGRQMLTSLSSPIINALVYEEMGVIEEGGLLDNFI
EEIMKNSTLKVVSAFVTDQNGKVLAHNQYTEYGKQYDDLLTRTAITEGRYQASLQKQPGQSGTLLNMAMPLHIYQKSWGA
LRVVVSTAPLEAQLQGLAKRIAATSLAFFLLGMAASYLIGRSMARPLQRLSEIMASVSTDNLLVELPPDRPDEIGKLQES
FRTMLERLRQSEAERKRAVTQLVQSEKLASLGKIVAGVAHEVNNPLGAINASIYNLEQKSGNQLRNMEIIKQGVERIERI
VRQLSDFSRTASLELQPLASEGFFSECAEFSRVALKRFDVELVTEDRCAPALMLQLDKGKIQQVLLNLLFNAAQASPLRG
IIRLSAQLTPGYYQLEVEDQGSGIPPEAQRTVFDIFYTTKHAGEGTGIGLAICKSIVEMHGGTITFSSRPGKTVFTVSLP
LTPTENGNELL
>Mature_490_residues
TRRFISIKTQFVLIAMLMVALSSTLWGVFAWKTERNLLYSNLENEGRQMLTSLSSPIINALVYEEMGVIEEGGLLDNFIE
EIMKNSTLKVVSAFVTDQNGKVLAHNQYTEYGKQYDDLLTRTAITEGRYQASLQKQPGQSGTLLNMAMPLHIYQKSWGAL
RVVVSTAPLEAQLQGLAKRIAATSLAFFLLGMAASYLIGRSMARPLQRLSEIMASVSTDNLLVELPPDRPDEIGKLQESF
RTMLERLRQSEAERKRAVTQLVQSEKLASLGKIVAGVAHEVNNPLGAINASIYNLEQKSGNQLRNMEIIKQGVERIERIV
RQLSDFSRTASLELQPLASEGFFSECAEFSRVALKRFDVELVTEDRCAPALMLQLDKGKIQQVLLNLLFNAAQASPLRGI
IRLSAQLTPGYYQLEVEDQGSGIPPEAQRTVFDIFYTTKHAGEGTGIGLAICKSIVEMHGGTITFSSRPGKTVFTVSLPL
TPTENGNELL

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=238, Percent_Identity=34.0336134453782, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=32.5102880658436, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786912, Length=259, Percent_Identity=31.2741312741313, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1790300, Length=243, Percent_Identity=32.5102880658436, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786783, Length=294, Percent_Identity=28.2312925170068, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790861, Length=400, Percent_Identity=26.75, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789808, Length=334, Percent_Identity=25.4491017964072, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=28.0155642023346, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788393, Length=300, Percent_Identity=23.6666666666667, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081816, Length=360, Percent_Identity=26.1111111111111, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI48994928, Length=247, Percent_Identity=26.7206477732794, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787894, Length=225, Percent_Identity=27.5555555555556, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54382; Mature: 54250

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRFISIKTQFVLIAMLMVALSSTLWGVFAWKTERNLLYSNLENEGRQMLTSLSSPIIN
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ALVYEEMGVIEEGGLLDNFIEEIMKNSTLKVVSAFVTDQNGKVLAHNQYTEYGKQYDDLL
HHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHH
TRTAITEGRYQASLQKQPGQSGTLLNMAMPLHIYQKSWGALRVVVSTAPLEAQLQGLAKR
HHHHHHCCHHHHHHHCCCCCCCCEEEEECHHHHHHCCCCEEEEEEECCCHHHHHHHHHHH
IAATSLAFFLLGMAASYLIGRSMARPLQRLSEIMASVSTDNLLVELPPDRPDEIGKLQES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHH
FRTMLERLRQSEAERKRAVTQLVQSEKLASLGKIVAGVAHEVNNPLGAINASIYNLEQKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEECHHHC
GNQLRNMEIIKQGVERIERIVRQLSDFSRTASLELQPLASEGFFSECAEFSRVALKRFDV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHCC
ELVTEDRCAPALMLQLDKGKIQQVLLNLLFNAAQASPLRGIIRLSAQLTPGYYQLEVEDQ
EEEECCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCEEEEEEECC
GSGIPPEAQRTVFDIFYTTKHAGEGTGIGLAICKSIVEMHGGTITFSSRPGKTVFTVSLP
CCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEEC
LTPTENGNELL
CCCCCCCCCCC
>Mature Secondary Structure 
TRRFISIKTQFVLIAMLMVALSSTLWGVFAWKTERNLLYSNLENEGRQMLTSLSSPIIN
CCEEEEHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ALVYEEMGVIEEGGLLDNFIEEIMKNSTLKVVSAFVTDQNGKVLAHNQYTEYGKQYDDLL
HHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHH
TRTAITEGRYQASLQKQPGQSGTLLNMAMPLHIYQKSWGALRVVVSTAPLEAQLQGLAKR
HHHHHHCCHHHHHHHCCCCCCCCEEEEECHHHHHHCCCCEEEEEEECCCHHHHHHHHHHH
IAATSLAFFLLGMAASYLIGRSMARPLQRLSEIMASVSTDNLLVELPPDRPDEIGKLQES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHH
FRTMLERLRQSEAERKRAVTQLVQSEKLASLGKIVAGVAHEVNNPLGAINASIYNLEQKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEECHHHC
GNQLRNMEIIKQGVERIERIVRQLSDFSRTASLELQPLASEGFFSECAEFSRVALKRFDV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHCC
ELVTEDRCAPALMLQLDKGKIQQVLLNLLFNAAQASPLRGIIRLSAQLTPGYYQLEVEDQ
EEEECCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCEEEEEEECC
GSGIPPEAQRTVFDIFYTTKHAGEGTGIGLAICKSIVEMHGGTITFSSRPGKTVFTVSLP
CCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEEC
LTPTENGNELL
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]