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The map label for this gene is gmhA

Identifier: 189424044

GI number: 189424044

Start: 1017044

End: 1017634

Strand: Reverse

Name: gmhA

Synonym: Glov_0978

Alternate gene names: 189424044

Gene position: 1017634-1017044 (Counterclockwise)

Preceding gene: 189424045

Following gene: 189424043

Centisome position: 25.97

GC content: 59.9

Gene sequence:

>591_bases
ATGCAATCATTTATCGCCAAGCAACTTCAGGACCACCTGGCCCTGTTTCAGAAGATGGAAGCCGAACTGACCGCACCGGT
GGCAGAACTTGCGGAGCGCCTGATTGAGACCTTCAAGATCGGCAACAAACTCCTGATCATGGGTAACGGCGGTTCGGCAG
CCGACGCCCAGCATTTTGCCGGAGAGATTGTCAGTCGTTTCAGGATTGAACGGCCCGGTCTGCCGGCTATAGCCCTTTCA
ACCGATACCTCCATCATAACCGCCATCGGCAACGATTACGGCTTTGAGCGGATCTTTTCCCGCCAGGTCGAGGCGCTGGC
GGTCCCGGGCGACGCGGTCATCGGCATCTCCACCAGCGGCAACTCTCCAAATGTCCAGAAGGCGCTGGAGGTGGCCCGCC
AGGCCGGCTGCACCACCATCGGCCTGCTGGGCAAAGACGGCGGCAGCATCAAGGCGGTCTGCGACATCCCGCTGATCATC
CCCTCCAATGACACCCCCCGGGTACAGGAAGGTCACATCGCCGTAATCCACATCCTCTGCGACCTGATCGAGCAGGGCCT
GTTCGGCATATTTGCCGGGGAAGGACGTTAG

Upstream 100 bases:

>100_bases
AGCCTGTCTGCGGTCTGGACGGCATTCCGTTTCCCGGCTATGATACAGCACTTCCAGCCGCCACCCTGACTCAACTGGCT
AATCCATAAGGAGGCAGTTC

Downstream 100 bases:

>100_bases
ACCATGGATCGTAAAATGGTCGAATCACTGTTTCAGCGCGCCTCCACCCTGAAATGTCTGGTTGTCGGCGACCTGATGCT
GGATGAATACCTCTGGGGCA

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MQSFIAKQLQDHLALFQKMEAELTAPVAELAERLIETFKIGNKLLIMGNGGSAADAQHFAGEIVSRFRIERPGLPAIALS
TDTSIITAIGNDYGFERIFSRQVEALAVPGDAVIGISTSGNSPNVQKALEVARQAGCTTIGLLGKDGGSIKAVCDIPLII
PSNDTPRVQEGHIAVIHILCDLIEQGLFGIFAGEGR

Sequences:

>Translated_196_residues
MQSFIAKQLQDHLALFQKMEAELTAPVAELAERLIETFKIGNKLLIMGNGGSAADAQHFAGEIVSRFRIERPGLPAIALS
TDTSIITAIGNDYGFERIFSRQVEALAVPGDAVIGISTSGNSPNVQKALEVARQAGCTTIGLLGKDGGSIKAVCDIPLII
PSNDTPRVQEGHIAVIHILCDLIEQGLFGIFAGEGR
>Mature_196_residues
MQSFIAKQLQDHLALFQKMEAELTAPVAELAERLIETFKIGNKLLIMGNGGSAADAQHFAGEIVSRFRIERPGLPAIALS
TDTSIITAIGNDYGFERIFSRQVEALAVPGDAVIGISTSGNSPNVQKALEVARQAGCTTIGLLGKDGGSIKAVCDIPLII
PSNDTPRVQEGHIAVIHILCDLIEQGLFGIFAGEGR

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1786416, Length=188, Percent_Identity=48.936170212766, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1789539, Length=165, Percent_Identity=43.6363636363636, Blast_Score=147, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GMHA_GEOLS (B3E5N0)

Other databases:

- EMBL:   CP001089
- RefSeq:   YP_001951221.1
- ProteinModelPortal:   B3E5N0
- SMR:   B3E5N0
- GeneID:   6366824
- GenomeReviews:   CP001089_GR
- KEGG:   glo:Glov_0978
- HOGENOM:   HBG671955
- OMA:   IGRYKRD
- ProtClustDB:   PRK13937
- GO:   GO:0005737
- HAMAP:   MF_00067
- InterPro:   IPR004515
- InterPro:   IPR020620
- InterPro:   IPR001347
- TIGRFAMs:   TIGR00441

Pfam domain/function: PF01380 SIS

EC number: =5.3.1.28

Molecular weight: Translated: 20778; Mature: 20778

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS51464 SIS

Important sites: BINDING 62-62 BINDING 122-122 BINDING 169-169

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSFIAKQLQDHLALFQKMEAELTAPVAELAERLIETFKIGNKLLIMGNGGSAADAQHFA
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHH
GEIVSRFRIERPGLPAIALSTDTSIITAIGNDYGFERIFSRQVEALAVPGDAVIGISTSG
HHHHHHHHCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHEEECCCCEEEEEECCC
NSPNVQKALEVARQAGCTTIGLLGKDGGSIKAVCDIPLIIPSNDTPRVQEGHIAVIHILC
CCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEEEEECCCCCCCCCCCCCHHHHHHH
DLIEQGLFGIFAGEGR
HHHHCCCEEEEECCCC
>Mature Secondary Structure
MQSFIAKQLQDHLALFQKMEAELTAPVAELAERLIETFKIGNKLLIMGNGGSAADAQHFA
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHH
GEIVSRFRIERPGLPAIALSTDTSIITAIGNDYGFERIFSRQVEALAVPGDAVIGISTSG
HHHHHHHHCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHEEECCCCEEEEEECCC
NSPNVQKALEVARQAGCTTIGLLGKDGGSIKAVCDIPLIIPSNDTPRVQEGHIAVIHILC
CCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEEEEECCCCCCCCCCCCCHHHHHHH
DLIEQGLFGIFAGEGR
HHHHCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA