| Definition | Geobacter lovleyi SZ chromosome, complete genome. |
|---|---|
| Accession | NC_010814 |
| Length | 3,917,761 |
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The map label for this gene is murE [H]
Identifier: 189423744
GI number: 189423744
Start: 683093
End: 684613
Strand: Reverse
Name: murE [H]
Synonym: Glov_0675
Alternate gene names: 189423744
Gene position: 684613-683093 (Counterclockwise)
Preceding gene: 189423745
Following gene: 189423743
Centisome position: 17.47
GC content: 59.89
Gene sequence:
>1521_bases ATGCTACTTGAACAACTGCTGCATGAGGTACCACTACAGGCCACCCACGGCAACCTGGATGTTACGGTTTCCGCGCTTAC CTGTGACTCACGCGAGGTGACGGCAGGTACACTCTTCTTTGCCCTGCACGGCAGCAAGGTGGACGGCCACCGCTTCATCT CCCAGGCCGTTACTGCCGGTGCAGCAGCCGTTGTTCTGGAAGATGCAAGCTATGCACCTGAACAGGTGCCCTGGTTACAG GTGACAAACGGGCGCCAGGCCATGGCACTGATGGCGGCCCGGTTCTTTGGCAACCCGACCCGTGATCTGCCGCTGATCGG CATCACCGGCACCAACGGCAAGACCACCACCAGCTACCTGCTGGAAGGAATTCTCACTGCTGCCGGTCTGCCGCCTGCCG TACTGGGCACTATCAGCTACCGTTTCGGCACCACCTGCATTGAAGCCAGCCATACCACACCGGAATCAACTGAACTGCAG GGCATCTTCCGCCAGCTGGCCGATGCAGGTGCACAGGCGTTTGTGATGGAGGTCTCCTCCCACAGCCTTGAGCAACGCAG GGTTGATGGTTCGGTCTTTGATATCGGAGTTTTTACCAACCTGACCCGTGACCACCTGGACTACCATGGCACCATGCAGG CCTACGGCAGCGCGAAGCAGCGCCTGTTCAGCGAACTGTTGAGGCCGGACGACCGGACTCCGCTGCGTCATGCCGTCATC AATGCCGATGATCCGGCAGCAGAAGAGTTCATCCGGGCGGCGGCCTGTCCGGTTATCCGTTACGGGCTGGCTCCCGGATC CGAGGTAACGGTCCGTGAGACGACCTCGTCGGTCAACGGGATCAGCGCGATTCTGGTGACGCCACAGGGGGAGCAACCGT TTCATTCACGCCTGCTGGGAGGGTTTAACCTTTCCAATATTTTGGCAGCTGCTGCCGCAGGAGTGGCGTTGGGGCTGCCG CTGCAGGCCATTATACAGGGGATCGAGCAGCACACCACCGTACCGGGACGGCTGGAGCGTGTTGAAAACAGAGCAGGCGT GACCTGCCTGGTTGACTATGCCCATACAGGTGATGCCCTTGAAAATGTCTTAAGCACCCTGAAGGATCTGGCCGGCGCCA GAATCATCACCGTGTTCGGCTGCGGCGGAGACCGGGATAACGGCAAGCGGCCGATCATGGGGCGGATTGCCGCCGGCTAT TCCGATCTGGCGGTTGTCACTTCGGACAATCCGCGTACCGAAGACCCCCACGAGATTTTGCGCCAGATCCGAGCGGGTAT TCTTCCGCTGGGGCTGCGGGAATACAGACCGGACGAACTGACTGCCCCCCCTGAAGACAAGGGGTTTGTCATGCTTGAGA ACCGCCGTGAGGCGATCAGACTTGCTGTGCGGCTGGCTCGGCCGGGTGACATCCTGCTGTTGGCAGGCAAGGGGCATGAA GATTACCAGATCATCGGCCAGACCAAACAACACTTTGACGACCGTGAGGAAGCAGCCAATGCATTCAGGGAGCGGATCTG A
Upstream 100 bases:
>100_bases CAGCGGGCGTGTCATTGAGCAGCATCCACAGCCTGGGCAGGTTATCCATGGCTCGGACGAAATTTGGGTTCGCCTGGCAC CCGCAGCATAAGGAACCATG
Downstream 100 bases:
>100_bases CATGTTCACCCCGGAACAACTGACAACCATCACCCATGGTCGATTGATCGGGCCTGAAACCGCATCGGTCAGCGGCATCT CAACTGACTCGCGTACCATC
Product: UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase
Products: NA
Alternate protein names: Meso-A2pm-adding enzyme; Meso-diaminopimelate-adding enzyme; UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; UDP-MurNAc-tripeptide synthetase; UDP-N-acetylmuramyl-tripeptide synthetase [H]
Number of amino acids: Translated: 506; Mature: 506
Protein sequence:
>506_residues MLLEQLLHEVPLQATHGNLDVTVSALTCDSREVTAGTLFFALHGSKVDGHRFISQAVTAGAAAVVLEDASYAPEQVPWLQ VTNGRQAMALMAARFFGNPTRDLPLIGITGTNGKTTTSYLLEGILTAAGLPPAVLGTISYRFGTTCIEASHTTPESTELQ GIFRQLADAGAQAFVMEVSSHSLEQRRVDGSVFDIGVFTNLTRDHLDYHGTMQAYGSAKQRLFSELLRPDDRTPLRHAVI NADDPAAEEFIRAAACPVIRYGLAPGSEVTVRETTSSVNGISAILVTPQGEQPFHSRLLGGFNLSNILAAAAAGVALGLP LQAIIQGIEQHTTVPGRLERVENRAGVTCLVDYAHTGDALENVLSTLKDLAGARIITVFGCGGDRDNGKRPIMGRIAAGY SDLAVVTSDNPRTEDPHEILRQIRAGILPLGLREYRPDELTAPPEDKGFVMLENRREAIRLAVRLARPGDILLLAGKGHE DYQIIGQTKQHFDDREEAANAFRERI
Sequences:
>Translated_506_residues MLLEQLLHEVPLQATHGNLDVTVSALTCDSREVTAGTLFFALHGSKVDGHRFISQAVTAGAAAVVLEDASYAPEQVPWLQ VTNGRQAMALMAARFFGNPTRDLPLIGITGTNGKTTTSYLLEGILTAAGLPPAVLGTISYRFGTTCIEASHTTPESTELQ GIFRQLADAGAQAFVMEVSSHSLEQRRVDGSVFDIGVFTNLTRDHLDYHGTMQAYGSAKQRLFSELLRPDDRTPLRHAVI NADDPAAEEFIRAAACPVIRYGLAPGSEVTVRETTSSVNGISAILVTPQGEQPFHSRLLGGFNLSNILAAAAAGVALGLP LQAIIQGIEQHTTVPGRLERVENRAGVTCLVDYAHTGDALENVLSTLKDLAGARIITVFGCGGDRDNGKRPIMGRIAAGY SDLAVVTSDNPRTEDPHEILRQIRAGILPLGLREYRPDELTAPPEDKGFVMLENRREAIRLAVRLARPGDILLLAGKGHE DYQIIGQTKQHFDDREEAANAFRERI >Mature_506_residues MLLEQLLHEVPLQATHGNLDVTVSALTCDSREVTAGTLFFALHGSKVDGHRFISQAVTAGAAAVVLEDASYAPEQVPWLQ VTNGRQAMALMAARFFGNPTRDLPLIGITGTNGKTTTSYLLEGILTAAGLPPAVLGTISYRFGTTCIEASHTTPESTELQ GIFRQLADAGAQAFVMEVSSHSLEQRRVDGSVFDIGVFTNLTRDHLDYHGTMQAYGSAKQRLFSELLRPDDRTPLRHAVI NADDPAAEEFIRAAACPVIRYGLAPGSEVTVRETTSSVNGISAILVTPQGEQPFHSRLLGGFNLSNILAAAAAGVALGLP LQAIIQGIEQHTTVPGRLERVENRAGVTCLVDYAHTGDALENVLSTLKDLAGARIITVFGCGGDRDNGKRPIMGRIAAGY SDLAVVTSDNPRTEDPHEILRQIRAGILPLGLREYRPDELTAPPEDKGFVMLENRREAIRLAVRLARPGDILLLAGKGHE DYQIIGQTKQHFDDREEAANAFRERI
Specific function: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan [H]
COG id: COG0769
COG function: function code M; UDP-N-acetylmuramyl tripeptide synthase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the MurCDEF family. MurE subfamily [H]
Homologues:
Organism=Escherichia coli, GI1786273, Length=483, Percent_Identity=38.3022774327122, Blast_Score=268, Evalue=5e-73,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004101 - InterPro: IPR013221 - InterPro: IPR000713 - InterPro: IPR005761 [H]
Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]
EC number: =6.3.2.13 [H]
Molecular weight: Translated: 54578; Mature: 54578
Theoretical pI: Translated: 5.72; Mature: 5.72
Prosite motif: PS01011 FOLYLPOLYGLU_SYNT_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.0 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 1.0 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLLEQLLHEVPLQATHGNLDVTVSALTCDSREVTAGTLFFALHGSKVDGHRFISQAVTAG CCHHHHHHHCCCEECCCCEEEEEEEEEECCCCCEEEEEEEEEECCCCCHHHHHHHHHHCC AAAVVLEDASYAPEQVPWLQVTNGRQAMALMAARFFGNPTRDLPLIGITGTNGKTTTSYL CEEEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHH LEGILTAAGLPPAVLGTISYRFGTTCIEASHTTPESTELQGIFRQLADAGAQAFVMEVSS HHHHHHHCCCCHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEHHH HSLEQRRVDGSVFDIGVFTNLTRDHLDYHGTMQAYGSAKQRLFSELLRPDDRTPLRHAVI HHHHHHHCCCCEEEEHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHEEE NADDPAAEEFIRAAACPVIRYGLAPGSEVTVRETTSSVNGISAILVTPQGEQPFHSRLLG CCCCHHHHHHHHHHHCHHHEECCCCCCEEEEEECCCCCCCEEEEEEECCCCCCHHHHHHC GFNLSNILAAAAAGVALGLPLQAIIQGIEQHTTVPGRLERVENRAGVTCLVDYAHTGDAL CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEECCCCHHH ENVLSTLKDLAGARIITVFGCGGDRDNGKRPIMGRIAAGYSDLAVVTSDNPRTEDPHEIL HHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCCHHHHH RQIRAGILPLGLREYRPDELTAPPEDKGFVMLENRREAIRLAVRLARPGDILLLAGKGHE HHHHHCCCCCCHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCEEEEECCCCC DYQIIGQTKQHFDDREEAANAFRERI CHHEECCHHHHCCHHHHHHHHHHHCC >Mature Secondary Structure MLLEQLLHEVPLQATHGNLDVTVSALTCDSREVTAGTLFFALHGSKVDGHRFISQAVTAG CCHHHHHHHCCCEECCCCEEEEEEEEEECCCCCEEEEEEEEEECCCCCHHHHHHHHHHCC AAAVVLEDASYAPEQVPWLQVTNGRQAMALMAARFFGNPTRDLPLIGITGTNGKTTTSYL CEEEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHH LEGILTAAGLPPAVLGTISYRFGTTCIEASHTTPESTELQGIFRQLADAGAQAFVMEVSS HHHHHHHCCCCHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEHHH HSLEQRRVDGSVFDIGVFTNLTRDHLDYHGTMQAYGSAKQRLFSELLRPDDRTPLRHAVI HHHHHHHCCCCEEEEHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHEEE NADDPAAEEFIRAAACPVIRYGLAPGSEVTVRETTSSVNGISAILVTPQGEQPFHSRLLG CCCCHHHHHHHHHHHCHHHEECCCCCCEEEEEECCCCCCCEEEEEEECCCCCCHHHHHHC GFNLSNILAAAAAGVALGLPLQAIIQGIEQHTTVPGRLERVENRAGVTCLVDYAHTGDAL CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEECCCCHHH ENVLSTLKDLAGARIITVFGCGGDRDNGKRPIMGRIAAGYSDLAVVTSDNPRTEDPHEIL HHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCCHHHHH RQIRAGILPLGLREYRPDELTAPPEDKGFVMLENRREAIRLAVRLARPGDILLLAGKGHE HHHHHCCCCCCHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCEEEEECCCCC DYQIIGQTKQHFDDREEAANAFRERI CHHEECCHHHHCCHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA