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The map label for this gene is mraY

Identifier: 189423742

GI number: 189423742

Start: 680622

End: 681698

Strand: Reverse

Name: mraY

Synonym: Glov_0673

Alternate gene names: 189423742

Gene position: 681698-680622 (Counterclockwise)

Preceding gene: 189423743

Following gene: 189423741

Centisome position: 17.4

GC content: 54.87

Gene sequence:

>1077_bases
ATGCTCTTTCACCTGTTCTACCCCCTGGCATCCAACCTGAAGATTCTGAACATCTTCAAGTATCTGACCTTCAGAACCAT
CTATGCCATGATCACGGCCCTGATCGTCTGTTTTGTCCTTGGACCCTGGATCATCCGCAAGCTGGAGGGGCTGCAGGCCC
GGCAGGTAATCCGGACCGATGGGCCGGAGTCCCACCTGGAAAAACAGGGTACCCCCACCATGGGCGGTCTGATCATCCTT
ACGGCCATTATCCTGCCAACCCTGCTCTGGGCCGACCTGACCAACGTCTATATCTGGCTGACCCTGTTCATCATTGTGGG
CTATGGTCTGATCGGCTTCATGGATGACTACCTCAAGGTGGTAAAGAAGAACACCAAAGGACTCTCGGCCAGACAAAAAA
TGTTCTGGCAAGTGCTGCTGGCAGGCGGCGTGGCGGTATTTCTCTACGTTACGCCCGGTTTCAATGAGATGTTGTATGTG
CCGTTTTTCAAGAATTTCCACCCTGATCTGGGGATATTCTTTATTCCGTTTGTCACCCTGGTTATTGTGGGTGCCAGCAA
TGCCGTCAACCTGACCGATGGACTGGATGGGCTGGCGATCGGCCCGGTGGCAATCAATGCCGCCACCTACATGCTGTTTG
CCTATGTTGCCGGCCATGCAACCCTTTCAGCCTACCTGCAGATCCCCCGCGTGGTCGGCGCCGGTGAACTGGCTGTAATC
TGCGGGGCCATGGTGGGGGCCGGTTTGGGGTTTCTCTGGTTCAACTCCTACCCGGCAGAGGTATTCATGGGGGATGTGGG
ATCACTTTCATTGGGTGGCACTCTGGGAGTCATTGCGGTCCTGACCAAGCAGGAGATCCTGCTGGTGATTGTAGGCGGCA
TCTTTGTGATCGAGGCGCTTTCGGTTATTTTCCAGGTAGGCTCCTACAAGTACCGCGGGAAACGGATCTTCCGCATGGCA
CCGATTCACCATCACTTTGAGCTGAAGGGGGTGGCAGAGCCCAAGATCATTGTCCGGTTCTGGATCATCACCATTATTCT
GGCCCTGGTGGCCATTTCAACCCTGAAGATGCGCTGA

Upstream 100 bases:

>100_bases
GGCAACGGCGACCTGATCTTGCTTAAGGGTTCACGGGGGATGAAGATGGAAAAAATCGCCGCGCTGCTGCGGGCTGCAGA
CGGCCAGGAGGACTAACACC

Downstream 100 bases:

>100_bases
CATGGAACTACGCACTAAAAAAACAACTGTCATGGGCCTCGCCAAAACCGGTGTGGCCTCTGCCCGTTTTCTGGCACAGC
AGGGTGCACGGGTAACCGCC

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MLFHLFYPLASNLKILNIFKYLTFRTIYAMITALIVCFVLGPWIIRKLEGLQARQVIRTDGPESHLEKQGTPTMGGLIIL
TAIILPTLLWADLTNVYIWLTLFIIVGYGLIGFMDDYLKVVKKNTKGLSARQKMFWQVLLAGGVAVFLYVTPGFNEMLYV
PFFKNFHPDLGIFFIPFVTLVIVGASNAVNLTDGLDGLAIGPVAINAATYMLFAYVAGHATLSAYLQIPRVVGAGELAVI
CGAMVGAGLGFLWFNSYPAEVFMGDVGSLSLGGTLGVIAVLTKQEILLVIVGGIFVIEALSVIFQVGSYKYRGKRIFRMA
PIHHHFELKGVAEPKIIVRFWIITIILALVAISTLKMR

Sequences:

>Translated_358_residues
MLFHLFYPLASNLKILNIFKYLTFRTIYAMITALIVCFVLGPWIIRKLEGLQARQVIRTDGPESHLEKQGTPTMGGLIIL
TAIILPTLLWADLTNVYIWLTLFIIVGYGLIGFMDDYLKVVKKNTKGLSARQKMFWQVLLAGGVAVFLYVTPGFNEMLYV
PFFKNFHPDLGIFFIPFVTLVIVGASNAVNLTDGLDGLAIGPVAINAATYMLFAYVAGHATLSAYLQIPRVVGAGELAVI
CGAMVGAGLGFLWFNSYPAEVFMGDVGSLSLGGTLGVIAVLTKQEILLVIVGGIFVIEALSVIFQVGSYKYRGKRIFRMA
PIHHHFELKGVAEPKIIVRFWIITIILALVAISTLKMR
>Mature_358_residues
MLFHLFYPLASNLKILNIFKYLTFRTIYAMITALIVCFVLGPWIIRKLEGLQARQVIRTDGPESHLEKQGTPTMGGLIIL
TAIILPTLLWADLTNVYIWLTLFIIVGYGLIGFMDDYLKVVKKNTKGLSARQKMFWQVLLAGGVAVFLYVTPGFNEMLYV
PFFKNFHPDLGIFFIPFVTLVIVGASNAVNLTDGLDGLAIGPVAINAATYMLFAYVAGHATLSAYLQIPRVVGAGELAVI
CGAMVGAGLGFLWFNSYPAEVFMGDVGSLSLGGTLGVIAVLTKQEILLVIVGGIFVIEALSVIFQVGSYKYRGKRIFRMA
PIHHHFELKGVAEPKIIVRFWIITIILALVAISTLKMR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=346, Percent_Identity=59.2485549132948, Blast_Score=399, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_GEOLS (B3E3Y5)

Other databases:

- EMBL:   CP001089
- RefSeq:   YP_001950919.1
- GeneID:   6369308
- GenomeReviews:   CP001089_GR
- KEGG:   glo:Glov_0673
- HOGENOM:   HBG708263
- OMA:   HATLSAY
- ProtClustDB:   PRK00108
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 39427; Mature: 39427

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12a3cd30)-; HASH(0x1368eb54)-; HASH(0x13678eac)-; HASH(0x132f6160)-; HASH(0x11499198)-; HASH(0x136a3320)-; HASH(0x12daad00)-; HASH(0x136a3218)-; HASH(0x1368b7ac)-; HASH(0x12bf2750)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFHLFYPLASNLKILNIFKYLTFRTIYAMITALIVCFVLGPWIIRKLEGLQARQVIRTD
CEEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
GPESHLEKQGTPTMGGLIILTAIILPTLLWADLTNVYIWLTLFIIVGYGLIGFMDDYLKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKKNTKGLSARQKMFWQVLLAGGVAVFLYVTPGFNEMLYVPFFKNFHPDLGIFFIPFVTL
HHHCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCEEEECHHHCCCCCCHHHHHHHHHH
VIVGASNAVNLTDGLDGLAIGPVAINAATYMLFAYVAGHATLSAYLQIPRVVGAGELAVI
HHHCCCCCEECCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
CGAMVGAGLGFLWFNSYPAEVFMGDVGSLSLGGTLGVIAVLTKQEILLVIVGGIFVIEAL
HHHHHHCCHHHHHCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVIFQVGSYKYRGKRIFRMAPIHHHFELKGVAEPKIIVRFWIITIILALVAISTLKMR
HHHHHHCCCEECCCEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MLFHLFYPLASNLKILNIFKYLTFRTIYAMITALIVCFVLGPWIIRKLEGLQARQVIRTD
CEEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
GPESHLEKQGTPTMGGLIILTAIILPTLLWADLTNVYIWLTLFIIVGYGLIGFMDDYLKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKKNTKGLSARQKMFWQVLLAGGVAVFLYVTPGFNEMLYVPFFKNFHPDLGIFFIPFVTL
HHHCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCEEEECHHHCCCCCCHHHHHHHHHH
VIVGASNAVNLTDGLDGLAIGPVAINAATYMLFAYVAGHATLSAYLQIPRVVGAGELAVI
HHHCCCCCEECCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
CGAMVGAGLGFLWFNSYPAEVFMGDVGSLSLGGTLGVIAVLTKQEILLVIVGGIFVIEAL
HHHHHHCCHHHHHCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVIFQVGSYKYRGKRIFRMAPIHHHFELKGVAEPKIIVRFWIITIILALVAISTLKMR
HHHHHHCCCEECCCEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA