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The map label for this gene is etfA [H]

Identifier: 189423641

GI number: 189423641

Start: 552002

End: 553333

Strand: Reverse

Name: etfA [H]

Synonym: Glov_0571

Alternate gene names: 189423641

Gene position: 553333-552002 (Counterclockwise)

Preceding gene: 189423642

Following gene: 189423640

Centisome position: 14.12

GC content: 58.86

Gene sequence:

>1332_bases
ATGAGTGAAAACACACCAAAGATCAAAAAACCCCGCGGACGCGCCCGCCTGCTGGAAGGCAAGTGTATTGCCTGCGGCGC
CCGCTGTGAAAGTTCCTGCCCGGTCAACTGCATCAGTATGAATGAAGCCGGTGAACCGGTAGTTGATACAGAAAAGTGTA
TCGGCTGCCTCAAGTGCGTCAAGGTCTGTCCGGCCCAGGCACTTGAAATGTTCTTCACCCCTGAAGAGCAGAAGATCCTC
GAACAGCTGGCAGCAGCAGGTAGCGCGCCCATAGCGGAAGAAGAGGATCCGGAGGCGGCTGCCATTGCCCGGATGCAGGC
CCAATACCGCGGGGTCTGGGTCTTTATCGAACAGACCGACGGTGAGGCGGCCAAGGTATCCTGGGAGCTGTTGGGCAAGG
GCAAGGAGCTGGCTGCCAAGCTGGGAGTCGAACTGTGTGCCGTGGTAATCGGCCACAAGGTTGAGCCGCTCTGCCACGAA
GCTTTCAAATACGGCGCAGAAAAGGCCTATCTGCTGGATGCACCGCTCTATGGCGATTACCGCACCCAGTCTTACCTGGA
AGCGATGTGCCACCTGATTGAGCAGCACAAACCCGAGGTGATCCTGATGGGGGCCACCGGCATGGGACGCGACCTGGCCG
GGGCAGTGGCCACCAGGGTCGGCACCGGCCTGACCGCTGACTGTACCGGCCTGGATATTGACGACAAACGCAACCTGATG
CAGACCCGTCCCGCCTTTGGCGGCAATATCATGGCCACCATCATGTGCGACAAATACCGGCCCCAGATGTCCACGGTCCG
GCCCCATGTGATGCAGATGCCCGAACCGCTGCCGGAGGCCACCGGCCAGATTATCCGGGATGCCTTTACCACCCCGGAAG
ATCAGGTACTGGCAAAGGTGCTTGAAATTATCCGCGACGGCGACAGCAAGCACAAGGTGGATATCGGCGGTGCCGAATTC
ATCATCTCCGGCGGGCGGGGCATGATGGGACCGGAAAACTTCGCCATGCTGGAAGAGCTGGCCAAAGAGCTGAACGGTGT
GGTGGGGGCTTCCCGTTCTGCAGTGGATGCGGGCTGGATGCCCCACGACCGGCAAGTCGGCCAGACCGGCAAGACCGTGC
GCCCCAAGATCTATATTGCCTGCGGCATTTCAGGTGCTATTCAGCACCTGGTGGGGATGCAGGATGCCGATCTGATCATC
GCCATCAACCGGGACAAGGATGCACCGATTTTTGAAGTGGCCCATTACGGCATTGTCGGCGATCTGTTCCAGATTGTACC
CGTCCTGACGCGTAAAATTCGTGAGCTGAAAACACGAGGCAAAAAACCATGA

Upstream 100 bases:

>100_bases
AACGCGACAAGGGTGAAATTGTAGGGGACGGCTATGCCGATCCGGAGGGAACGGTTGATTTATTGCTGGGTAAACTGATG
GAAAAGGATCTGCTACCACT

Downstream 100 bases:

>100_bases
CACCAACCCCGACCATTTTCGCACCACTCTTTATTGCCGCCACGGCCCTGTTTGTCTGGAGCTGCTGGAAACGACTCTCA
CTGACCGCCCTGGGACGCCC

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MSENTPKIKKPRGRARLLEGKCIACGARCESSCPVNCISMNEAGEPVVDTEKCIGCLKCVKVCPAQALEMFFTPEEQKIL
EQLAAAGSAPIAEEEDPEAAAIARMQAQYRGVWVFIEQTDGEAAKVSWELLGKGKELAAKLGVELCAVVIGHKVEPLCHE
AFKYGAEKAYLLDAPLYGDYRTQSYLEAMCHLIEQHKPEVILMGATGMGRDLAGAVATRVGTGLTADCTGLDIDDKRNLM
QTRPAFGGNIMATIMCDKYRPQMSTVRPHVMQMPEPLPEATGQIIRDAFTTPEDQVLAKVLEIIRDGDSKHKVDIGGAEF
IISGGRGMMGPENFAMLEELAKELNGVVGASRSAVDAGWMPHDRQVGQTGKTVRPKIYIACGISGAIQHLVGMQDADLII
AINRDKDAPIFEVAHYGIVGDLFQIVPVLTRKIRELKTRGKKP

Sequences:

>Translated_443_residues
MSENTPKIKKPRGRARLLEGKCIACGARCESSCPVNCISMNEAGEPVVDTEKCIGCLKCVKVCPAQALEMFFTPEEQKIL
EQLAAAGSAPIAEEEDPEAAAIARMQAQYRGVWVFIEQTDGEAAKVSWELLGKGKELAAKLGVELCAVVIGHKVEPLCHE
AFKYGAEKAYLLDAPLYGDYRTQSYLEAMCHLIEQHKPEVILMGATGMGRDLAGAVATRVGTGLTADCTGLDIDDKRNLM
QTRPAFGGNIMATIMCDKYRPQMSTVRPHVMQMPEPLPEATGQIIRDAFTTPEDQVLAKVLEIIRDGDSKHKVDIGGAEF
IISGGRGMMGPENFAMLEELAKELNGVVGASRSAVDAGWMPHDRQVGQTGKTVRPKIYIACGISGAIQHLVGMQDADLII
AINRDKDAPIFEVAHYGIVGDLFQIVPVLTRKIRELKTRGKKP
>Mature_442_residues
SENTPKIKKPRGRARLLEGKCIACGARCESSCPVNCISMNEAGEPVVDTEKCIGCLKCVKVCPAQALEMFFTPEEQKILE
QLAAAGSAPIAEEEDPEAAAIARMQAQYRGVWVFIEQTDGEAAKVSWELLGKGKELAAKLGVELCAVVIGHKVEPLCHEA
FKYGAEKAYLLDAPLYGDYRTQSYLEAMCHLIEQHKPEVILMGATGMGRDLAGAVATRVGTGLTADCTGLDIDDKRNLMQ
TRPAFGGNIMATIMCDKYRPQMSTVRPHVMQMPEPLPEATGQIIRDAFTTPEDQVLAKVLEIIRDGDSKHKVDIGGAEFI
ISGGRGMMGPENFAMLEELAKELNGVVGASRSAVDAGWMPHDRQVGQTGKTVRPKIYIACGISGAIQHLVGMQDADLIIA
INRDKDAPIFEVAHYGIVGDLFQIVPVLTRKIRELKTRGKKP

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=335, Percent_Identity=32.5373134328358, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI189181759, Length=241, Percent_Identity=39.0041493775934, Blast_Score=163, Evalue=3e-40,
Organism=Escherichia coli, GI1787990, Length=333, Percent_Identity=30.3303303303303, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1786226, Length=273, Percent_Identity=29.6703296703297, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI87082157, Length=259, Percent_Identity=23.5521235521236, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17506929, Length=300, Percent_Identity=35.6666666666667, Blast_Score=156, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6325261, Length=359, Percent_Identity=32.3119777158774, Blast_Score=147, Evalue=4e-36,
Organism=Drosophila melanogaster, GI17136898, Length=298, Percent_Identity=35.2348993288591, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24652801, Length=298, Percent_Identity=35.2348993288591, Blast_Score=166, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 48106; Mature: 47975

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS00198 4FE4S_FERREDOXIN ; PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENTPKIKKPRGRARLLEGKCIACGARCESSCPVNCISMNEAGEPVVDTEKCIGCLKCV
CCCCCCCCCCCCCCCEEECCCEEEECCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
KVCPAQALEMFFTPEEQKILEQLAAAGSAPIAEEEDPEAAAIARMQAQYRGVWVFIEQTD
HHCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCEEEEEEECCC
GEAAKVSWELLGKGKELAAKLGVELCAVVIGHKVEPLCHEAFKYGAEKAYLLDAPLYGDY
CCHHEEEHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCCCCCH
RTQSYLEAMCHLIEQHKPEVILMGATGMGRDLAGAVATRVGTGLTADCTGLDIDDKRNLM
HHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
QTRPAFGGNIMATIMCDKYRPQMSTVRPHVMQMPEPLPEATGQIIRDAFTTPEDQVLAKV
HCCCCCCCCEEEEEEECCCCCCHHHCCHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHH
LEIIRDGDSKHKVDIGGAEFIISGGRGMMGPENFAMLEELAKELNGVVGASRSAVDAGWM
HHHHHCCCCCCEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PHDRQVGQTGKTVRPKIYIACGISGAIQHLVGMQDADLIIAINRDKDAPIFEVAHYGIVG
CCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHH
DLFQIVPVLTRKIRELKTRGKKP
HHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SENTPKIKKPRGRARLLEGKCIACGARCESSCPVNCISMNEAGEPVVDTEKCIGCLKCV
CCCCCCCCCCCCCCEEECCCEEEECCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
KVCPAQALEMFFTPEEQKILEQLAAAGSAPIAEEEDPEAAAIARMQAQYRGVWVFIEQTD
HHCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCEEEEEEECCC
GEAAKVSWELLGKGKELAAKLGVELCAVVIGHKVEPLCHEAFKYGAEKAYLLDAPLYGDY
CCHHEEEHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEECCCCCCH
RTQSYLEAMCHLIEQHKPEVILMGATGMGRDLAGAVATRVGTGLTADCTGLDIDDKRNLM
HHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
QTRPAFGGNIMATIMCDKYRPQMSTVRPHVMQMPEPLPEATGQIIRDAFTTPEDQVLAKV
HCCCCCCCCEEEEEEECCCCCCHHHCCHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHH
LEIIRDGDSKHKVDIGGAEFIISGGRGMMGPENFAMLEELAKELNGVVGASRSAVDAGWM
HHHHHCCCCCCEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PHDRQVGQTGKTVRPKIYIACGISGAIQHLVGMQDADLIIAINRDKDAPIFEVAHYGIVG
CCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHH
DLFQIVPVLTRKIRELKTRGKKP
HHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA