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The map label for this gene is czcB [H]

Identifier: 189423608

GI number: 189423608

Start: 508185

End: 509387

Strand: Reverse

Name: czcB [H]

Synonym: Glov_0537

Alternate gene names: 189423608

Gene position: 509387-508185 (Counterclockwise)

Preceding gene: 189423609

Following gene: 189423607

Centisome position: 13.0

GC content: 54.36

Gene sequence:

>1203_bases
GTGAAGAAAAGGACATTACTCGTCAGCTTGTTGCTGTTGGCAGCCATTGGCAGCGGACTGTATTACCGCATCACCACCCA
AGGTGATGCAGAAAAGGCTGAACCAAAAGAAGCCGGCAGCAAAGATACAAAGGCTGAAAAGCACGAGGAAGACGGCAAGG
TCAAAATGACCGCTGAGCTCCAGCAACAGAACGGCGTCGCGGTCGGAACAGCCGCAACACAGCGTCTTGCCGGTGTTATC
AGCGCTACCGGCAAGGTTGATGTCAATAGCGACAGGATCGCCCATGTATCCCCCCGGATCTCCGGCAAGATCGTATCCGT
CAGATCCTCGCTCGGGGATCAGGTCTCCGCTGGCCAGGTCCTGGTGACCCTGGACAGTGTGGAGCTTGGTGAGGCCTTGA
ACCGCTACCATCAATCAAAGACCAAACTGGCTCTGGCGCAATCCAGCATGGACCGGATCAAGCTCCTGGTGGACAAGAAG
ATTGCGGCACGCAAGGACATCCTTCTGGCTGAAACCGAATTCAAAACCGCCCAGACAGAACTCCATACCGATGAGGAACG
GCTTGCCCTCTACGGCGTCTCTCTTGCTGACCTGACCAATACCCGGCATAGAAGCCCCTTGTTGCCGGTACGTTCACCAA
TCAGCGGCATCATTACAGAGAAGCACGCCATTGTTGGAGAATTGGCTGATCCTTCCAAAAACCTCTTCACCATTGCAGAT
CTTTCCTCGGTTTGGATCATGGTGGATATCAACGAAAAGGATCTGGCAAAGATCCATCGCGGCCAGATCGCCTCGGTTAG
CGTGAGTGCCTTCCCGGACCTGAAGCTGCAGGGACGTATCACCTATATTGCCGATCTGGTGGATCAGAACACCCGCACGG
TCAAGGCGCGTATCGAGGTGGCCAACCTGCAGCGTAAATTGAAACCGGAGATGTTCGCCAGCGTTGAGTTGAAACTTGCC
GCAGATGCACCACCGGTACTGGCGGTACCGGAAGAGTCCCTGCAGGATCTGGACGGCAAAAAAGTGGTCTTTGTTGTGGA
AGGTAAAGACACCTTTGTCCCGAGGCCGGTGCAGGCTGGCCGGATGGCAAACGGCAAGATTGAGATATTGTCCGGCTTGC
AGGAAGGCGAGCTGTACGCGGTCAAGGGTGCCTTTATCCTGAAGTCAGAACTGAAAAAAGCTGAAATGAAGGATGAGCAC
TAA

Upstream 100 bases:

>100_bases
TTGAAGTGAGTGAAGGCCACCTGACGGCCCTGCGCGACCGGCAGGTAGCGTTGGTGAGGCTTGAGTCAGCCACTGCAACA
GAACTCACCGGAGGTGAAAA

Downstream 100 bases:

>100_bases
CGTGGCTAGACACTCGACAATGGAAGCGAGGTTCCGATGCTGGAAAAATTAATTGCGTATACCTTACGTCAGAAGGGCAT
GGTTATCTTCCTGGCGCTGC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MKKRTLLVSLLLLAAIGSGLYYRITTQGDAEKAEPKEAGSKDTKAEKHEEDGKVKMTAELQQQNGVAVGTAATQRLAGVI
SATGKVDVNSDRIAHVSPRISGKIVSVRSSLGDQVSAGQVLVTLDSVELGEALNRYHQSKTKLALAQSSMDRIKLLVDKK
IAARKDILLAETEFKTAQTELHTDEERLALYGVSLADLTNTRHRSPLLPVRSPISGIITEKHAIVGELADPSKNLFTIAD
LSSVWIMVDINEKDLAKIHRGQIASVSVSAFPDLKLQGRITYIADLVDQNTRTVKARIEVANLQRKLKPEMFASVELKLA
ADAPPVLAVPEESLQDLDGKKVVFVVEGKDTFVPRPVQAGRMANGKIEILSGLQEGELYAVKGAFILKSELKKAEMKDEH

Sequences:

>Translated_400_residues
MKKRTLLVSLLLLAAIGSGLYYRITTQGDAEKAEPKEAGSKDTKAEKHEEDGKVKMTAELQQQNGVAVGTAATQRLAGVI
SATGKVDVNSDRIAHVSPRISGKIVSVRSSLGDQVSAGQVLVTLDSVELGEALNRYHQSKTKLALAQSSMDRIKLLVDKK
IAARKDILLAETEFKTAQTELHTDEERLALYGVSLADLTNTRHRSPLLPVRSPISGIITEKHAIVGELADPSKNLFTIAD
LSSVWIMVDINEKDLAKIHRGQIASVSVSAFPDLKLQGRITYIADLVDQNTRTVKARIEVANLQRKLKPEMFASVELKLA
ADAPPVLAVPEESLQDLDGKKVVFVVEGKDTFVPRPVQAGRMANGKIEILSGLQEGELYAVKGAFILKSELKKAEMKDEH
>Mature_400_residues
MKKRTLLVSLLLLAAIGSGLYYRITTQGDAEKAEPKEAGSKDTKAEKHEEDGKVKMTAELQQQNGVAVGTAATQRLAGVI
SATGKVDVNSDRIAHVSPRISGKIVSVRSSLGDQVSAGQVLVTLDSVELGEALNRYHQSKTKLALAQSSMDRIKLLVDKK
IAARKDILLAETEFKTAQTELHTDEERLALYGVSLADLTNTRHRSPLLPVRSPISGIITEKHAIVGELADPSKNLFTIAD
LSSVWIMVDINEKDLAKIHRGQIASVSVSAFPDLKLQGRITYIADLVDQNTRTVKARIEVANLQRKLKPEMFASVELKLA
ADAPPVLAVPEESLQDLDGKKVVFVVEGKDTFVPRPVQAGRMANGKIEILSGLQEGELYAVKGAFILKSELKKAEMKDEH

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=335, Percent_Identity=28.6567164179104, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081796, Length=320, Percent_Identity=25.3125, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789929, Length=307, Percent_Identity=24.1042345276873, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43494; Mature: 43494

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRTLLVSLLLLAAIGSGLYYRITTQGDAEKAEPKEAGSKDTKAEKHEEDGKVKMTAEL
CCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHCCCCCCCCCCCCCCCCEEEEEEE
QQQNGVAVGTAATQRLAGVISATGKVDVNSDRIAHVSPRISGKIVSVRSSLGDQVSAGQV
HHCCCEEEEHHHHHHHHHHHHCCCEEECCCCCEEEECCCCCCEEEEEHHHCCCCCCCCEE
LVTLDSVELGEALNRYHQSKTKLALAQSSMDRIKLLVDKKIAARKDILLAETEFKTAQTE
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHH
LHTDEERLALYGVSLADLTNTRHRSPLLPVRSPISGIITEKHAIVGELADPSKNLFTIAD
CCCCCHHEEEEECCHHHHCCCCCCCCCCCCCCCHHHHHCCCHHHEEECCCCCCCEEEEEE
LSSVWIMVDINEKDLAKIHRGQIASVSVSAFPDLKLQGRITYIADLVDQNTRTVKARIEV
CCEEEEEEEECHHHHHHHHCCCEEEEEEECCCCEEECCEEEEEEHHHCCCCEEEEEEEEH
ANLQRKLKPEMFASVELKLAADAPPVLAVPEESLQDLDGKKVVFVVEGKDTFVPRPVQAG
HHHHHHHCCHHEEEEEEEEECCCCCEEECCHHHHHCCCCCEEEEEECCCCCCCCCCCCCC
RMANGKIEILSGLQEGELYAVKGAFILKSELKKAEMKDEH
CCCCCEEEEECCCCCCCEEEEECHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKRTLLVSLLLLAAIGSGLYYRITTQGDAEKAEPKEAGSKDTKAEKHEEDGKVKMTAEL
CCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHCCCCCCCCCCCCCCCCEEEEEEE
QQQNGVAVGTAATQRLAGVISATGKVDVNSDRIAHVSPRISGKIVSVRSSLGDQVSAGQV
HHCCCEEEEHHHHHHHHHHHHCCCEEECCCCCEEEECCCCCCEEEEEHHHCCCCCCCCEE
LVTLDSVELGEALNRYHQSKTKLALAQSSMDRIKLLVDKKIAARKDILLAETEFKTAQTE
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHH
LHTDEERLALYGVSLADLTNTRHRSPLLPVRSPISGIITEKHAIVGELADPSKNLFTIAD
CCCCCHHEEEEECCHHHHCCCCCCCCCCCCCCCHHHHHCCCHHHEEECCCCCCCEEEEEE
LSSVWIMVDINEKDLAKIHRGQIASVSVSAFPDLKLQGRITYIADLVDQNTRTVKARIEV
CCEEEEEEEECHHHHHHHHCCCEEEEEEECCCCEEECCEEEEEEHHHCCCCEEEEEEEEH
ANLQRKLKPEMFASVELKLAADAPPVLAVPEESLQDLDGKKVVFVVEGKDTFVPRPVQAG
HHHHHHHCCHHEEEEEEEEECCCCCEEECCHHHHHCCCCCEEEEEECCCCCCCCCCCCCC
RMANGKIEILSGLQEGELYAVKGAFILKSELKKAEMKDEH
CCCCCEEEEECCCCCCCEEEEECHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]