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The map label for this gene is czcC [H]

Identifier: 189423609

GI number: 189423609

Start: 509384

End: 510682

Strand: Reverse

Name: czcC [H]

Synonym: Glov_0538

Alternate gene names: 189423609

Gene position: 510682-509384 (Counterclockwise)

Preceding gene: 189423610

Following gene: 189423608

Centisome position: 13.04

GC content: 56.74

Gene sequence:

>1299_bases
TTGAGCAGAACACTACGCGCACAGGGAGCATTATCCCTGTTGACAGTCATTTTCGTCATGGCCCTGTCCAGCACGGCCTG
GGCGGTAGAGTCAACACTCTCGTTGTCCCATGTCATTGCACTTTCGATGCAGCACAATGCCGAGCTGCGGGCGTTGCGCG
AGGAGCTGGGTGTCCGCGACGCCGGTGTGACCAGAGCCGGTCTGCTGCCGAATCCAACCCTTGACCTTGAAGCCGGCACC
GGCGCACTGACCGGCAGCAAAAATGAAAACAGCCTGGCACTTGGCCTGTCACAAGAGATCCCGCTTGTCGGCAAGCGCGG
AAAACGCCTTTCAGTTGCCGAACAGGAACGGGATCTCTACCGCTGGCAGTTGCTGGATAAGGAGCGTCGGTTACGAGAAG
AGGTGAAGACCGCCTTCTATGATGCCCTGCTGGCAAAAGAGCGCGTTGCGCTGGCTGACCGTTCCATTGCGCTCAACCGG
CAACTCCTTGACGTAACCAAAGAACGCCTGTCCGCCGGAGACATCCCGGAACTGGAGATGAATCTCGTCAAGGTTGAACT
GGCGCGGAGTGAAGGGGCCAGGATCGAAAGTGCGAAAACGATGCTCCAAAATCAGGCGCGACTCTGGACGCTGATGGGAC
TTGCCAGCGGCAGTCGGCCAGAAATCACCGGCACGCTGGACATCGGCACGCTGGTGGCGGGGACTCTGGCAGACCTGCAA
CAGCGTGCCAATGCCAACCGTCCTGACCTCAGGGCGCTTAAAGCGGAAAAAAAGCGGGGAGAGGCTGATATTACGCTTGC
CCAAGCCGAAAAGATTCCCAACCTGACAGCAGGTCTGGTGCTGCGGCGTGACACGACCTCCATGGAAATCGCAGGCCAAG
AAGGCAAGGATACCGCCTATACCGTTGGGATACGGCTCTCGATACCGATTCCGCTCTTTGACAGAAACCGGGCAGGCGTT
CAAGAGGCAACTGCCAGGAAGAACAGCACTGAAAGCCGCTTAAACGGTACTTTCATGGCTGTGGAACGTGAAGTTGCTAC
CGCATATGCAACGTTTGAGCATGCCGTATCGGTGCTTTCTCTCTACAGAATCGACATAATCCCGCAACTTGAGGAAAACC
TGAAGCTGACCCAGGAAGCTTACCGTCTGGGCGAAACCGGCATCATTGCAGTTATCCAGGAACAGAAAAAATTCTTTGAA
GTGAGTGAAGGCCACCTGACGGCCCTGCGCGACCGGCAGGTAGCGTTGGTGAGGCTTGAGTCAGCCACTGCAACAGAACT
CACCGGAGGTGAAAAGTGA

Upstream 100 bases:

>100_bases
TCGCCCTGATCCACAGGGACACCTGCGTCCATTTCCCGTCGTAGTACGCCTACAACCGCTGTTCAGCCGATCATACAACT
GAATAAAAGGAGAACATCTC

Downstream 100 bases:

>100_bases
AGAAAAGGACATTACTCGTCAGCTTGTTGCTGTTGGCAGCCATTGGCAGCGGACTGTATTACCGCATCACCACCCAAGGT
GATGCAGAAAAGGCTGAACC

Product: outer membrane efflux protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MSRTLRAQGALSLLTVIFVMALSSTAWAVESTLSLSHVIALSMQHNAELRALREELGVRDAGVTRAGLLPNPTLDLEAGT
GALTGSKNENSLALGLSQEIPLVGKRGKRLSVAEQERDLYRWQLLDKERRLREEVKTAFYDALLAKERVALADRSIALNR
QLLDVTKERLSAGDIPELEMNLVKVELARSEGARIESAKTMLQNQARLWTLMGLASGSRPEITGTLDIGTLVAGTLADLQ
QRANANRPDLRALKAEKKRGEADITLAQAEKIPNLTAGLVLRRDTTSMEIAGQEGKDTAYTVGIRLSIPIPLFDRNRAGV
QEATARKNSTESRLNGTFMAVEREVATAYATFEHAVSVLSLYRIDIIPQLEENLKLTQEAYRLGETGIIAVIQEQKKFFE
VSEGHLTALRDRQVALVRLESATATELTGGEK

Sequences:

>Translated_432_residues
MSRTLRAQGALSLLTVIFVMALSSTAWAVESTLSLSHVIALSMQHNAELRALREELGVRDAGVTRAGLLPNPTLDLEAGT
GALTGSKNENSLALGLSQEIPLVGKRGKRLSVAEQERDLYRWQLLDKERRLREEVKTAFYDALLAKERVALADRSIALNR
QLLDVTKERLSAGDIPELEMNLVKVELARSEGARIESAKTMLQNQARLWTLMGLASGSRPEITGTLDIGTLVAGTLADLQ
QRANANRPDLRALKAEKKRGEADITLAQAEKIPNLTAGLVLRRDTTSMEIAGQEGKDTAYTVGIRLSIPIPLFDRNRAGV
QEATARKNSTESRLNGTFMAVEREVATAYATFEHAVSVLSLYRIDIIPQLEENLKLTQEAYRLGETGIIAVIQEQKKFFE
VSEGHLTALRDRQVALVRLESATATELTGGEK
>Mature_431_residues
SRTLRAQGALSLLTVIFVMALSSTAWAVESTLSLSHVIALSMQHNAELRALREELGVRDAGVTRAGLLPNPTLDLEAGTG
ALTGSKNENSLALGLSQEIPLVGKRGKRLSVAEQERDLYRWQLLDKERRLREEVKTAFYDALLAKERVALADRSIALNRQ
LLDVTKERLSAGDIPELEMNLVKVELARSEGARIESAKTMLQNQARLWTLMGLASGSRPEITGTLDIGTLVAGTLADLQQ
RANANRPDLRALKAEKKRGEADITLAQAEKIPNLTAGLVLRRDTTSMEIAGQEGKDTAYTVGIRLSIPIPLFDRNRAGVQ
EATARKNSTESRLNGTFMAVEREVATAYATFEHAVSVLSLYRIDIIPQLEENLKLTQEAYRLGETGIIAVIQEQKKFFEV
SEGHLTALRDRQVALVRLESATATELTGGEK

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 47373; Mature: 47242

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTLRAQGALSLLTVIFVMALSSTAWAVESTLSLSHVIALSMQHNAELRALREELGVRD
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHCCCC
AGVTRAGLLPNPTLDLEAGTGALTGSKNENSLALGLSQEIPLVGKRGKRLSVAEQERDLY
CCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHH
RWQLLDKERRLREEVKTAFYDALLAKERVALADRSIALNRQLLDVTKERLSAGDIPELEM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHH
NLVKVELARSEGARIESAKTMLQNQARLWTLMGLASGSRPEITGTLDIGTLVAGTLADLQ
EEEEEEEECCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEEHHHHHHHHHHHHH
QRANANRPDLRALKAEKKRGEADITLAQAEKIPNLTAGLVLRRDTTSMEIAGQEGKDTAY
HHHCCCCCHHHHHHHHHHCCCCCEEEEHHHCCCCCCCCEEEEECCCCEEEECCCCCCCEE
TVGIRLSIPIPLFDRNRAGVQEATARKNSTESRLNGTFMAVEREVATAYATFEHAVSVLS
EEEEEEEECCCCCCCCCCCHHHHHHHCCCCHHHHCCEEEEEHHHHHHHHHHHHHHHHHHH
LYRIDIIPQLEENLKLTQEAYRLGETGIIAVIQEQKKFFEVSEGHLTALRDRQVALVRLE
HHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHCCCCCCEEEECCCCEEEEEEC
SATATELTGGEK
CCCCCCCCCCCC
>Mature Secondary Structure 
SRTLRAQGALSLLTVIFVMALSSTAWAVESTLSLSHVIALSMQHNAELRALREELGVRD
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHCCCC
AGVTRAGLLPNPTLDLEAGTGALTGSKNENSLALGLSQEIPLVGKRGKRLSVAEQERDLY
CCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHH
RWQLLDKERRLREEVKTAFYDALLAKERVALADRSIALNRQLLDVTKERLSAGDIPELEM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHH
NLVKVELARSEGARIESAKTMLQNQARLWTLMGLASGSRPEITGTLDIGTLVAGTLADLQ
EEEEEEEECCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEEHHHHHHHHHHHHH
QRANANRPDLRALKAEKKRGEADITLAQAEKIPNLTAGLVLRRDTTSMEIAGQEGKDTAY
HHHCCCCCHHHHHHHHHHCCCCCEEEEHHHCCCCCCCCEEEEECCCCEEEECCCCCCCEE
TVGIRLSIPIPLFDRNRAGVQEATARKNSTESRLNGTFMAVEREVATAYATFEHAVSVLS
EEEEEEEECCCCCCCCCCCHHHHHHHCCCCHHHHCCEEEEEHHHHHHHHHHHHHHHHHHH
LYRIDIIPQLEENLKLTQEAYRLGETGIIAVIQEQKKFFEVSEGHLTALRDRQVALVRLE
HHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHCCCCCCEEEECCCCEEEEEEC
SATATELTGGEK
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]