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The map label for this gene is adhB [H]

Identifier: 189423537

GI number: 189423537

Start: 437756

End: 438910

Strand: Reverse

Name: adhB [H]

Synonym: Glov_0466

Alternate gene names: 189423537

Gene position: 438910-437756 (Counterclockwise)

Preceding gene: 189423540

Following gene: 189423536

Centisome position: 11.2

GC content: 58.35

Gene sequence:

>1155_bases
ATGGCGGTTGATACTCTTCTACGCAAGTTTCTGATTCCGGAAATGATCTATGGCAACGGCGCCCATCAGCTGACAGGGCA
GTATGCAGGCCGTTTCGGCATCAGCAACGCTTTGGTGGTGAGCGATCCAGGCGTTGTGGAGGTCGGTTGGACCGGCCGGA
TCATGGAAAACCTGGCCCTGGCAGGTATTACGGCTGTTCCGTTTACCGAGATCACCCCCAACCCAAAGGACCATGAGGTC
ATGGCCGGTGTCGAGCGCTACCATGCGGCCGGCTGTGACGGCATTGTGACCGTTGGAGGAGGAAGTCCGATGGATTGCGC
CAAGGGGATCGGTATCGTCTGTTCCAACGGCGGACATATCCTCGATTATGAAGGCGTGGATCAGGTGCCGATGGCAATGC
CGCCTTTGATCTGCGTCCCCAGTACCGCCGGTTCAGCTGCAGATGTCTCTCAGTTTGCCATCATTACCGACACAGCCGAC
CGGAGAAAGGTTGCCATCATCAGCAAGTCTGTGGTTCCAGACCTGGCCTTGATCGATCCCCTGCTGACCACCACCATGCC
TGCCGAACTGACCGCCTGCACCGGCATGGACGCCCTGGTCCATGCCATTGAGGCCTATGTCTCCAACGCCAGCTCATCTT
TTACTGATCTGCATGCACTGCATGCGATACGTCTCGTCACGCGTCACCTCGCCGAAGCCATCGAAAAACCGGCTTCGCTG
GAGGCCCGCAACGGCATGATGCTGGCCAGCACCCAGGCAGGCATGGCCTTCTCCAATGCCAGTCTGGGGGCAGTCCATGC
CATGGCCCACAGCCTGGGCGGATTGATTGACTCCCCCCACGGCGAATGCAACGCCCAGCTGCTGGAACACGTCATTGCCT
ACAACTATGGCTCTGCTGCAGAGCGTTACCAAGAGGTCAGCCACGCCATGGGAATCGACTGCCCTGCGGGACAGGATTCC
TGTACAGCGCTGACTGCGGGGATCCGCACACTGCGGATGTCGATCGGCATCACCAGAACCATTTCAGCGCCGGGGATACA
CTATGAGCAGATCCCCTCGCTGGCAGAAAAAGCGATGCTGGATGCCTGCATGGTTACCAATCCGCGACGACCGACACAAA
AGGATATTGAAAAGATCTATGCGGCGGCGTTCTGA

Upstream 100 bases:

>100_bases
CGGCCATTAATTTAGCATTTTCTGCCCGGCAGCCTTGCTTAGTAGACAATAAGGCGTAAAATAATTACAAATACATGAGG
CTGCAGCGCAGGGGGCAGAT

Downstream 100 bases:

>100_bases
AGAGCATAGCCGGGACTGGTCTGAGCTGCGCAACCGGATCATTGGTTTGGGAGAACAGTCATCCCACAAAAACTACTATT
CCGAGCTGAAGGCAAGATTG

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: Alcohol dehydrogenase II; ADH II [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MAVDTLLRKFLIPEMIYGNGAHQLTGQYAGRFGISNALVVSDPGVVEVGWTGRIMENLALAGITAVPFTEITPNPKDHEV
MAGVERYHAAGCDGIVTVGGGSPMDCAKGIGIVCSNGGHILDYEGVDQVPMAMPPLICVPSTAGSAADVSQFAIITDTAD
RRKVAIISKSVVPDLALIDPLLTTTMPAELTACTGMDALVHAIEAYVSNASSSFTDLHALHAIRLVTRHLAEAIEKPASL
EARNGMMLASTQAGMAFSNASLGAVHAMAHSLGGLIDSPHGECNAQLLEHVIAYNYGSAAERYQEVSHAMGIDCPAGQDS
CTALTAGIRTLRMSIGITRTISAPGIHYEQIPSLAEKAMLDACMVTNPRRPTQKDIEKIYAAAF

Sequences:

>Translated_384_residues
MAVDTLLRKFLIPEMIYGNGAHQLTGQYAGRFGISNALVVSDPGVVEVGWTGRIMENLALAGITAVPFTEITPNPKDHEV
MAGVERYHAAGCDGIVTVGGGSPMDCAKGIGIVCSNGGHILDYEGVDQVPMAMPPLICVPSTAGSAADVSQFAIITDTAD
RRKVAIISKSVVPDLALIDPLLTTTMPAELTACTGMDALVHAIEAYVSNASSSFTDLHALHAIRLVTRHLAEAIEKPASL
EARNGMMLASTQAGMAFSNASLGAVHAMAHSLGGLIDSPHGECNAQLLEHVIAYNYGSAAERYQEVSHAMGIDCPAGQDS
CTALTAGIRTLRMSIGITRTISAPGIHYEQIPSLAEKAMLDACMVTNPRRPTQKDIEKIYAAAF
>Mature_383_residues
AVDTLLRKFLIPEMIYGNGAHQLTGQYAGRFGISNALVVSDPGVVEVGWTGRIMENLALAGITAVPFTEITPNPKDHEVM
AGVERYHAAGCDGIVTVGGGSPMDCAKGIGIVCSNGGHILDYEGVDQVPMAMPPLICVPSTAGSAADVSQFAIITDTADR
RKVAIISKSVVPDLALIDPLLTTTMPAELTACTGMDALVHAIEAYVSNASSSFTDLHALHAIRLVTRHLAEAIEKPASLE
ARNGMMLASTQAGMAFSNASLGAVHAMAHSLGGLIDSPHGECNAQLLEHVIAYNYGSAAERYQEVSHAMGIDCPAGQDSC
TALTAGIRTLRMSIGITRTISAPGIHYEQIPSLAEKAMLDACMVTNPRRPTQKDIEKIYAAAF

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=409, Percent_Identity=27.3838630806846, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI48994951, Length=379, Percent_Identity=41.4248021108179, Blast_Score=273, Evalue=1e-74,
Organism=Escherichia coli, GI1789163, Length=383, Percent_Identity=33.420365535248, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI87082107, Length=387, Percent_Identity=33.3333333333333, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI1787493, Length=380, Percent_Identity=32.1052631578947, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1789386, Length=313, Percent_Identity=26.1980830670927, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17537053, Length=385, Percent_Identity=23.1168831168831, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6321181, Length=378, Percent_Identity=38.6243386243386, Blast_Score=251, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24657991, Length=405, Percent_Identity=24.6913580246914, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 40339; Mature: 40208

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00913 ADH_IRON_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVDTLLRKFLIPEMIYGNGAHQLTGQYAGRFGISNALVVSDPGVVEVGWTGRIMENLAL
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCCEEEECCCHHHHHHHHH
AGITAVPFTEITPNPKDHEVMAGVERYHAAGCDGIVTVGGGSPMDCAKGIGIVCSNGGHI
HCCEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHCCCEEEECCCCEE
LDYEGVDQVPMAMPPLICVPSTAGSAADVSQFAIITDTADRRKVAIISKSVVPDLALIDP
EECCCCCCCCCCCCCEEEECCCCCCCCCHHEEEEEECCCCCCEEEEEEHHHCCHHHHHHH
LLTTTMPAELTACTGMDALVHAIEAYVSNASSSFTDLHALHAIRLVTRHLAEAIEKPASL
HHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
EARNGMMLASTQAGMAFSNASLGAVHAMAHSLGGLIDSPHGECNAQLLEHVIAYNYGSAA
HHCCCEEEEECCCCCEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHH
ERYQEVSHAMGIDCPAGQDSCTALTAGIRTLRMSIGITRTISAPGIHYEQIPSLAEKAML
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCEEEECCCCCCCHHHHHHHHHHHHH
DACMVTNPRRPTQKDIEKIYAAAF
HHHHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
AVDTLLRKFLIPEMIYGNGAHQLTGQYAGRFGISNALVVSDPGVVEVGWTGRIMENLAL
CHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEECCCCEEEECCCHHHHHHHHH
AGITAVPFTEITPNPKDHEVMAGVERYHAAGCDGIVTVGGGSPMDCAKGIGIVCSNGGHI
HCCEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHCCCEEEECCCCEE
LDYEGVDQVPMAMPPLICVPSTAGSAADVSQFAIITDTADRRKVAIISKSVVPDLALIDP
EECCCCCCCCCCCCCEEEECCCCCCCCCHHEEEEEECCCCCCEEEEEEHHHCCHHHHHHH
LLTTTMPAELTACTGMDALVHAIEAYVSNASSSFTDLHALHAIRLVTRHLAEAIEKPASL
HHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
EARNGMMLASTQAGMAFSNASLGAVHAMAHSLGGLIDSPHGECNAQLLEHVIAYNYGSAA
HHCCCEEEEECCCCCEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHH
ERYQEVSHAMGIDCPAGQDSCTALTAGIRTLRMSIGITRTISAPGIHYEQIPSLAEKAML
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCEEEECCCCCCCHHHHHHHHHHHHH
DACMVTNPRRPTQKDIEKIYAAAF
HHHHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3584063; 2308827; 2935393 [H]