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The map label for this gene is mcp4 [H]

Identifier: 189423532

GI number: 189423532

Start: 432295

End: 434004

Strand: Reverse

Name: mcp4 [H]

Synonym: Glov_0461

Alternate gene names: 189423532

Gene position: 434004-432295 (Counterclockwise)

Preceding gene: 189423533

Following gene: 189423531

Centisome position: 11.08

GC content: 59.82

Gene sequence:

>1710_bases
ATGAAACGTTACCGCGACTGGTGCATCCAATGCAAGATTGTCAGCATCACCCTGCTGACCATGCTATTACTGATTTCAGC
GCTCTTCGGCTACATCCTGCCGATGTTCAGGGACAACCTGATGACAGAGAAAGAACTGGCCACCCGCCATATCGTGGAAC
TGGCCATGGGGGTCCTGGAGCAGTATGATGCCGCTGCCAAATCCGGCAAACTGCCCCTTGAACAGGCCCAGCAGGAGGCA
ACTGAGCAGATCGCCAGGCTACGCTATGAAGGCAAGGAATATCTCTGGATCAATGACCTTGGCAAACCTGCCCCCAGGAT
GATCATGCACCCCACGGTGCCGGCCCTGAACGGCAAGGTCCTGGATGACACCAAGTTTAACAAGGCCACATTGATGCAGG
ATGCTGCGGATGGGCCAACCAAGAAACTGGACAATATGAACCTGTTTTCCGCCTTTGTTGAGGTGGCTGACCGCGCCGGA
CACGGCTTTGTGATGTACCAGTGGCCCAAGCCCAAACAGGGCGGCGGTACAACTGAAGAACTGTACCCCAAACTCTCCTA
TGTCAAAAAATTTGCGCCATGGGGCTGGGTGTTGGGGAGCGGTATCTACGTGGATGATGTCGACAAACAGGCTGCCAGGG
TAATGTGGACCCTGCTGGCCGGTACCCTGCTGCTGGCTGCCTGCGGTATCGCCATTGCCGTTGCCATTGGCCGCGGGGTG
GTACGCCCGATGAACACCATGCAGCAGGCCCTGGAACAGATGGCCAGCGGCGAAGGGGATCTGACCCGGCGCCTGCCGAT
CCAGCGCGAGGACGAGACCGGAGTCCTGGCCCGCACCTTTAACCGCTTTCTTGAAAACCTGCACAACATCATCCGCGACG
TGTCACAGGGGACCCAAGAACTCAACTCCGCTGCTGACCGTCTTCATGCAACCGCAGAACACATTGCCGACAGCTCGCTT
GAGATGTCATCCCAATCGGTGTCGGTGGCAACCGCCGTTGAAGAGATGGCAGCCACCTCCCAGAGTATTGCCCAGAGCTG
CGCCCAGGCCTATGAAAATGCCAACCGCGCCTGCCTGACGGCCCAGGATGGCTCTGCGGTAGTCAGCCAGGCTGTGGCCA
GCATCCGGGCCATTGCCGACCGGGTACAGGAAAGCTCCCATACGGTAGAAACACTGGGAGCCCGCTCGGACCAGATCGGA
CAGATTATCGGCACCATCGAGGACATTGCCGATCAGACCAACCTGCTGGCACTGAATGCCGCCATAGAAGCGGCCCGGGC
CGGTGAGATGGGACGCGGGTTTGCCGTGGTGGCCGATGAGGTGCGGGCCCTGGCAGAGCGGACCACCCGGGCCACCCGGG
AGATCGGCGAAATGATCAAGGTCATCCAGCAGGAGACCGCCACAGCGGTCGCCAGCATGGGCGCCGGAGTGCAGGCGGTA
GAGCAGGGTACCATCGAGGCGGCAAAATCAGGGCAGGCCCTGGAGGAGATCCTGGCTCAAATCTCTGAAGTGACCAGCCA
GATCAACCAGATCGCCACTGCCGCCGAAGAACAGACCGCCACCACCAACGACATCAGCGGTAACATGCAGCGGATTGTCT
CAGCAGTGGACACAAGCACAGCCCAGGCCCATGCCACCGGTCAGGAGGCGACCGAGCTTGCAAACATGTCCGGCAACCTG
GCCAACCTGGTAGGCCGGTTCAGGGTCTAG

Upstream 100 bases:

>100_bases
AGATCCACGGTTCCTACACCAATGTGGTGGGGCTGCCCACCTGTGAACTGGTGGAGACCCTGCATACCATCGGCGCATGG
CCTAAAGAGGAGCAACACTA

Downstream 100 bases:

>100_bases
CTGATGTCTGTCACCGGTAATCTTGCTGCAGTGCAGGCCCGCATACAACGAGCCTGCACGATCTCGGGCAGAGCCCCTTC
CACGGTGCGGCTGGTGGCGG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MKRYRDWCIQCKIVSITLLTMLLLISALFGYILPMFRDNLMTEKELATRHIVELAMGVLEQYDAAAKSGKLPLEQAQQEA
TEQIARLRYEGKEYLWINDLGKPAPRMIMHPTVPALNGKVLDDTKFNKATLMQDAADGPTKKLDNMNLFSAFVEVADRAG
HGFVMYQWPKPKQGGGTTEELYPKLSYVKKFAPWGWVLGSGIYVDDVDKQAARVMWTLLAGTLLLAACGIAIAVAIGRGV
VRPMNTMQQALEQMASGEGDLTRRLPIQREDETGVLARTFNRFLENLHNIIRDVSQGTQELNSAADRLHATAEHIADSSL
EMSSQSVSVATAVEEMAATSQSIAQSCAQAYENANRACLTAQDGSAVVSQAVASIRAIADRVQESSHTVETLGARSDQIG
QIIGTIEDIADQTNLLALNAAIEAARAGEMGRGFAVVADEVRALAERTTRATREIGEMIKVIQQETATAVASMGAGVQAV
EQGTIEAAKSGQALEEILAQISEVTSQINQIATAAEEQTATTNDISGNMQRIVSAVDTSTAQAHATGQEATELANMSGNL
ANLVGRFRV

Sequences:

>Translated_569_residues
MKRYRDWCIQCKIVSITLLTMLLLISALFGYILPMFRDNLMTEKELATRHIVELAMGVLEQYDAAAKSGKLPLEQAQQEA
TEQIARLRYEGKEYLWINDLGKPAPRMIMHPTVPALNGKVLDDTKFNKATLMQDAADGPTKKLDNMNLFSAFVEVADRAG
HGFVMYQWPKPKQGGGTTEELYPKLSYVKKFAPWGWVLGSGIYVDDVDKQAARVMWTLLAGTLLLAACGIAIAVAIGRGV
VRPMNTMQQALEQMASGEGDLTRRLPIQREDETGVLARTFNRFLENLHNIIRDVSQGTQELNSAADRLHATAEHIADSSL
EMSSQSVSVATAVEEMAATSQSIAQSCAQAYENANRACLTAQDGSAVVSQAVASIRAIADRVQESSHTVETLGARSDQIG
QIIGTIEDIADQTNLLALNAAIEAARAGEMGRGFAVVADEVRALAERTTRATREIGEMIKVIQQETATAVASMGAGVQAV
EQGTIEAAKSGQALEEILAQISEVTSQINQIATAAEEQTATTNDISGNMQRIVSAVDTSTAQAHATGQEATELANMSGNL
ANLVGRFRV
>Mature_569_residues
MKRYRDWCIQCKIVSITLLTMLLLISALFGYILPMFRDNLMTEKELATRHIVELAMGVLEQYDAAAKSGKLPLEQAQQEA
TEQIARLRYEGKEYLWINDLGKPAPRMIMHPTVPALNGKVLDDTKFNKATLMQDAADGPTKKLDNMNLFSAFVEVADRAG
HGFVMYQWPKPKQGGGTTEELYPKLSYVKKFAPWGWVLGSGIYVDDVDKQAARVMWTLLAGTLLLAACGIAIAVAIGRGV
VRPMNTMQQALEQMASGEGDLTRRLPIQREDETGVLARTFNRFLENLHNIIRDVSQGTQELNSAADRLHATAEHIADSSL
EMSSQSVSVATAVEEMAATSQSIAQSCAQAYENANRACLTAQDGSAVVSQAVASIRAIADRVQESSHTVETLGARSDQIG
QIIGTIEDIADQTNLLALNAAIEAARAGEMGRGFAVVADEVRALAERTTRATREIGEMIKVIQQETATAVASMGAGVQAV
EQGTIEAAKSGQALEEILAQISEVTSQINQIATAAEEQTATTNDISGNMQRIVSAVDTSTAQAHATGQEATELANMSGNL
ANLVGRFRV

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=325, Percent_Identity=32.3076923076923, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1787690, Length=366, Percent_Identity=32.2404371584699, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1788195, Length=449, Percent_Identity=28.5077951002227, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1788194, Length=350, Percent_Identity=29.7142857142857, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI1789453, Length=318, Percent_Identity=31.4465408805031, Blast_Score=111, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 61474; Mature: 61474

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRYRDWCIQCKIVSITLLTMLLLISALFGYILPMFRDNLMTEKELATRHIVELAMGVLE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
QYDAAAKSGKLPLEQAQQEATEQIARLRYEGKEYLWINDLGKPAPRMIMHPTVPALNGKV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEECCCCCCCCCEE
LDDTKFNKATLMQDAADGPTKKLDNMNLFSAFVEVADRAGHGFVMYQWPKPKQGGGTTEE
CCCCCCCHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHH
LYPKLSYVKKFAPWGWVLGSGIYVDDVDKQAARVMWTLLAGTLLLAACGIAIAVAIGRGV
HHHHHHHHHHHCCCHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
VRPMNTMQQALEQMASGEGDLTRRLPIQREDETGVLARTFNRFLENLHNIIRDVSQGTQE
HCHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNSAADRLHATAEHIADSSLEMSSQSVSVATAVEEMAATSQSIAQSCAQAYENANRACLT
HHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
AQDGSAVVSQAVASIRAIADRVQESSHTVETLGARSDQIGQIIGTIEDIADQTNLLALNA
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHEEHHHH
AIEAARAGEMGRGFAVVADEVRALAERTTRATREIGEMIKVIQQETATAVASMGAGVQAV
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
EQGTIEAAKSGQALEEILAQISEVTSQINQIATAAEEQTATTNDISGNMQRIVSAVDTST
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCH
AQAHATGQEATELANMSGNLANLVGRFRV
HHHHCCHHHHHHHHHCCCCHHHHHHHCCC
>Mature Secondary Structure
MKRYRDWCIQCKIVSITLLTMLLLISALFGYILPMFRDNLMTEKELATRHIVELAMGVLE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
QYDAAAKSGKLPLEQAQQEATEQIARLRYEGKEYLWINDLGKPAPRMIMHPTVPALNGKV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEECCCCCCCCCEE
LDDTKFNKATLMQDAADGPTKKLDNMNLFSAFVEVADRAGHGFVMYQWPKPKQGGGTTEE
CCCCCCCHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHH
LYPKLSYVKKFAPWGWVLGSGIYVDDVDKQAARVMWTLLAGTLLLAACGIAIAVAIGRGV
HHHHHHHHHHHCCCHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
VRPMNTMQQALEQMASGEGDLTRRLPIQREDETGVLARTFNRFLENLHNIIRDVSQGTQE
HCHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNSAADRLHATAEHIADSSLEMSSQSVSVATAVEEMAATSQSIAQSCAQAYENANRACLT
HHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
AQDGSAVVSQAVASIRAIADRVQESSHTVETLGARSDQIGQIIGTIEDIADQTNLLALNA
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHEEHHHH
AIEAARAGEMGRGFAVVADEVRALAERTTRATREIGEMIKVIQQETATAVASMGAGVQAV
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
EQGTIEAAKSGQALEEILAQISEVTSQINQIATAAEEQTATTNDISGNMQRIVSAVDTST
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCH
AQAHATGQEATELANMSGNLANLVGRFRV
HHHHCCHHHHHHHHHCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]