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The map label for this gene is foxA [H]

Identifier: 189354072

GI number: 189354072

Start: 2406835

End: 2408940

Strand: Direct

Name: foxA [H]

Synonym: BMULJ_05325

Alternate gene names: 189354072

Gene position: 2406835-2408940 (Clockwise)

Preceding gene: 189354071

Following gene: 189354074

Centisome position: 97.32

GC content: 67.85

Gene sequence:

>2106_bases
ATGAGCAGGAAAAACTGGGCGGCCGCACCGATGGCCATCGTCGTCGGCACCGCCGGGCTGAGCAGCGCCGAGGCTCAGGA
ATTGTCGCTGCCCGCGATCGAAGTCTCCGGGCAGCGCACGACGGCGCCGTTTCGCGCGCCCGAATCGACGAGCGCGACAC
GCACTGAGACGGACGTGATGGAGATTCCGTTCGCCGTCAGCAGCGTCGATACGAAGCTGATCCGCACCGTCGCCGCGACA
CGCGGCGACGACCTGTACGACTGGGTCGCCGGCGTCGCGCGGCAGAACAACTTCGGCGGCCTGTGGGACAACTACGCCGT
GCGAGGCTTCGCGGGCGACGGCGGCACGTCCGGCACCGACTACCTCGTCAACGGCTTCTCGTGGAATCGCGGGATGAGCG
TGCCGCGCGACACGGCGACGCTCGAACGCATGGAAGTCCTCAAGGGCCCGGCGTCGGCGCTGTATGGCCGCGGCGACCCC
GGCGGGCTCATCAGCTACACGACGAAGCAGCCGCAGTTCGCGCCGTCGAACACGATCGGCGTATCGGCAGGCAGCTACGG
CGCGCTGCGCCAGACGCTCGATTCGACCGGCCCCGTCACGAAGTCGCTCGCCTACCGCTTCATCGCGATGAACGAGGACA
ACGGCAGCTTCCGCGATACGGTGTCGAGCAAGCGCTATCTGTTCGCGCCGTCGTTCACGTGGGATATCGGCGACGACACG
ACGCTCCATTACGAATTCGAGACGGCACGGCAGCGCGCACCGCTCGATCGCGGCGTGGTCGCCGTCAACGGGCAGCTCGG
CGCGGTGCCGGCGTCGCGGTTCATGGGCGAGCCGCGCGACGGCGACTACGACGTGCGCAACTCGGGCCATCAGCTCACGC
TCGAACATCGCTTCAACGCCGACTGGTCGATCAACGCCGGCTTCGCACAGCGCGATACCGACCTGTCCGGCCGCTCGTCC
GAGGCGTTCGCGCTGCAGCCGGACGGGCGCACGCTGTGGCGCCGCTACCGGCAGGTCGCGTTTCACTCGAACGACCTGCA
GGGGCGCGTCGAGGTGGCCGGCAAGGCGCGCACCGGCGCGATCGGCCACATGTTCGTGATGGGCGTCGATGCGTACCGCT
TCAACTACGACCAGTTCGTTGCGCGCTCGACGCCGACGGCCGCGGCGCCGTACGCGATCGACATCTTCAACCCGGTCTAC
GGCCAGCCGGCGCCCGTGCCGCGCACCGCGACGAACCTGCTCGAGCGCGACGACGGCCAGGGCCTGTACGCGCAGGACAC
GCTCGCGTTCGGGCCGCACTGGAAAGTACTTGCGGGGCTGCGCTGGGATCGCTTTCATCAGTCGGTCGAGAATCGCCTGA
AAGGCGTGACGACGAGCCAGCTGCAAACGGCGGTGAGCCCGCGGCTCGGGATCGTGTACGAGGCGAGTCCCTCGCTGTCG
CTGTATGCGAACACCGCGTACTCGTTCCGCCCGAACAACGGCGCCGACGTGAACGGCCGCGCATTCGATCCCGAAAAAGG
CCACGGCTATGAAGCCGGCGTGAAGTGGGCCGGCACGCGCTGGCTCGCGACCGTCGCCGCGTTCTACGTGAACAAGCGCA
ACGTGCTGACCGCCGATCCGGCGAATGCCGGGTTCTCGCGCGCGGCTGGCGAAGTGCGTAGCCGCGGCGTCGAATTCGAA
TGGAACGGCGAACTCGGCCACGGCCTGCGCGGCATCGTCAATCTCGCGTACGTCGATGCGCAGGTCACGCGCGACAGCGT
GCTGACGCCCGGTGCCCGCCTCGTCGACATTCCGCGCCTGAGCGGCAGTGCGCTGCTGATGTACGAGACCGCGCTGCCGC
TCGTCGACAAGGCCGGCGCAGGTGCGGGCGTGATCTACGTCGGCCGTCGCGCCGGCAACACCGCGAACACGCAGGACGGC
TTCGATCTGCCCGCTTATGCGACGGTGCAGCTCAACGGCTACGTGCAGGTCAACAAGCATCTGCGTGCGTCGGTCGTGCT
GAATAACCTGTTCAACCGCACGTACTACGTCAGTTCGTACAACAGCCTGTGGGTCACGCCGGGCGCGCCGCGCAGCCTGT
TCGCGTCGCTCTCTTACACGTTCTAG

Upstream 100 bases:

>100_bases
ACATTAGATTTCGGCGCGCAAATGTACTGTTTGGATCACGAATGCCGGCGCTGGACGGCTCGCGGTGCCCGAACGCGAAC
CCATCTCTGAAGGACGAGGT

Downstream 100 bases:

>100_bases
TCCCGCTGCGCGCCGCGCACGGCGACCGCCGCCGTGCGTGGTACGCGCCGTGCCGGTACGTCACCGTCGCGCCACGCCTG
TCGTGCCGCGCACCACGAGC

Product: ligand-gated channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 701; Mature: 700

Protein sequence:

>701_residues
MSRKNWAAAPMAIVVGTAGLSSAEAQELSLPAIEVSGQRTTAPFRAPESTSATRTETDVMEIPFAVSSVDTKLIRTVAAT
RGDDLYDWVAGVARQNNFGGLWDNYAVRGFAGDGGTSGTDYLVNGFSWNRGMSVPRDTATLERMEVLKGPASALYGRGDP
GGLISYTTKQPQFAPSNTIGVSAGSYGALRQTLDSTGPVTKSLAYRFIAMNEDNGSFRDTVSSKRYLFAPSFTWDIGDDT
TLHYEFETARQRAPLDRGVVAVNGQLGAVPASRFMGEPRDGDYDVRNSGHQLTLEHRFNADWSINAGFAQRDTDLSGRSS
EAFALQPDGRTLWRRYRQVAFHSNDLQGRVEVAGKARTGAIGHMFVMGVDAYRFNYDQFVARSTPTAAAPYAIDIFNPVY
GQPAPVPRTATNLLERDDGQGLYAQDTLAFGPHWKVLAGLRWDRFHQSVENRLKGVTTSQLQTAVSPRLGIVYEASPSLS
LYANTAYSFRPNNGADVNGRAFDPEKGHGYEAGVKWAGTRWLATVAAFYVNKRNVLTADPANAGFSRAAGEVRSRGVEFE
WNGELGHGLRGIVNLAYVDAQVTRDSVLTPGARLVDIPRLSGSALLMYETALPLVDKAGAGAGVIYVGRRAGNTANTQDG
FDLPAYATVQLNGYVQVNKHLRASVVLNNLFNRTYYVSSYNSLWVTPGAPRSLFASLSYTF

Sequences:

>Translated_701_residues
MSRKNWAAAPMAIVVGTAGLSSAEAQELSLPAIEVSGQRTTAPFRAPESTSATRTETDVMEIPFAVSSVDTKLIRTVAAT
RGDDLYDWVAGVARQNNFGGLWDNYAVRGFAGDGGTSGTDYLVNGFSWNRGMSVPRDTATLERMEVLKGPASALYGRGDP
GGLISYTTKQPQFAPSNTIGVSAGSYGALRQTLDSTGPVTKSLAYRFIAMNEDNGSFRDTVSSKRYLFAPSFTWDIGDDT
TLHYEFETARQRAPLDRGVVAVNGQLGAVPASRFMGEPRDGDYDVRNSGHQLTLEHRFNADWSINAGFAQRDTDLSGRSS
EAFALQPDGRTLWRRYRQVAFHSNDLQGRVEVAGKARTGAIGHMFVMGVDAYRFNYDQFVARSTPTAAAPYAIDIFNPVY
GQPAPVPRTATNLLERDDGQGLYAQDTLAFGPHWKVLAGLRWDRFHQSVENRLKGVTTSQLQTAVSPRLGIVYEASPSLS
LYANTAYSFRPNNGADVNGRAFDPEKGHGYEAGVKWAGTRWLATVAAFYVNKRNVLTADPANAGFSRAAGEVRSRGVEFE
WNGELGHGLRGIVNLAYVDAQVTRDSVLTPGARLVDIPRLSGSALLMYETALPLVDKAGAGAGVIYVGRRAGNTANTQDG
FDLPAYATVQLNGYVQVNKHLRASVVLNNLFNRTYYVSSYNSLWVTPGAPRSLFASLSYTF
>Mature_700_residues
SRKNWAAAPMAIVVGTAGLSSAEAQELSLPAIEVSGQRTTAPFRAPESTSATRTETDVMEIPFAVSSVDTKLIRTVAATR
GDDLYDWVAGVARQNNFGGLWDNYAVRGFAGDGGTSGTDYLVNGFSWNRGMSVPRDTATLERMEVLKGPASALYGRGDPG
GLISYTTKQPQFAPSNTIGVSAGSYGALRQTLDSTGPVTKSLAYRFIAMNEDNGSFRDTVSSKRYLFAPSFTWDIGDDTT
LHYEFETARQRAPLDRGVVAVNGQLGAVPASRFMGEPRDGDYDVRNSGHQLTLEHRFNADWSINAGFAQRDTDLSGRSSE
AFALQPDGRTLWRRYRQVAFHSNDLQGRVEVAGKARTGAIGHMFVMGVDAYRFNYDQFVARSTPTAAAPYAIDIFNPVYG
QPAPVPRTATNLLERDDGQGLYAQDTLAFGPHWKVLAGLRWDRFHQSVENRLKGVTTSQLQTAVSPRLGIVYEASPSLSL
YANTAYSFRPNNGADVNGRAFDPEKGHGYEAGVKWAGTRWLATVAAFYVNKRNVLTADPANAGFSRAAGEVRSRGVEFEW
NGELGHGLRGIVNLAYVDAQVTRDSVLTPGARLVDIPRLSGSALLMYETALPLVDKAGAGAGVIYVGRRAGNTANTQDGF
DLPAYATVQLNGYVQVNKHLRASVVLNNLFNRTYYVSSYNSLWVTPGAPRSLFASLSYTF

Specific function: Ferrioxamine binding and uptake, in association with the tonB protein. May play a role in intestinal colonization [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=759, Percent_Identity=26.0869565217391, Blast_Score=175, Evalue=1e-44,
Organism=Escherichia coli, GI1787344, Length=637, Percent_Identity=23.861852433281, Blast_Score=112, Evalue=9e-26,
Organism=Escherichia coli, GI1787024, Length=771, Percent_Identity=24.124513618677, Blast_Score=102, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 76114; Mature: 75982

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKNWAAAPMAIVVGTAGLSSAEAQELSLPAIEVSGQRTTAPFRAPESTSATRTETDVM
CCCCCCCCCCEEEEEECCCCCCCCHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHE
EIPFAVSSVDTKLIRTVAATRGDDLYDWVAGVARQNNFGGLWDNYAVRGFAGDGGTSGTD
ECCEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCC
YLVNGFSWNRGMSVPRDTATLERMEVLKGPASALYGRGDPGGLISYTTKQPQFAPSNTIG
EEEECCCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCCCCCCCEEEEECCCCCCCCCCEEE
VSAGSYGALRQTLDSTGPVTKSLAYRFIAMNEDNGSFRDTVSSKRYLFAPSFTWDIGDDT
ECCCCHHHHHHHHHCCCCHHHHEEEEEEEEECCCCCHHHHCCCCEEEECCCEEEECCCCC
TLHYEFETARQRAPLDRGVVAVNGQLGAVPASRFMGEPRDGDYDVRNSGHQLTLEHRFNA
EEEEEEHHHHHCCCCCCCEEEECCCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEEEECCC
DWSINAGFAQRDTDLSGRSSEAFALQPDGRTLWRRYRQVAFHSNDLQGRVEVAGKARTGA
CEEECCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCC
IGHMFVMGVDAYRFNYDQFVARSTPTAAAPYAIDIFNPVYGQPAPVPRTATNLLERDDGQ
CEEEEEEECCCEEECHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCC
GLYAQDTLAFGPHWKVLAGLRWDRFHQSVENRLKGVTTSQLQTAVSPRLGIVYEASPSLS
CEEEECCEEECCCCCEEECCCHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCCCEE
LYANTAYSFRPNNGADVNGRAFDPEKGHGYEAGVKWAGTRWLATVAAFYVNKRNVLTADP
EEECCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHCCCCEEEECC
ANAGFSRAAGEVRSRGVEFEWNGELGHGLRGIVNLAYVDAQVTRDSVLTPGARLVDIPRL
CCCCHHHHHHHHHHCCCCEEECCCCCCCHHHHEEEEEEEEECCCCHHCCCCCEEEEECCC
SGSALLMYETALPLVDKAGAGAGVIYVGRRAGNTANTQDGFDLPAYATVQLNGYVQVNKH
CCCEEEEEECCCCHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEEEEEEEECCH
LRASVVLNNLFNRTYYVSSYNSLWVTPGAPRSLFASLSYTF
HHHHHHHHHHHCCEEEEECCCEEEECCCCCHHHHHHHCCCC
>Mature Secondary Structure 
SRKNWAAAPMAIVVGTAGLSSAEAQELSLPAIEVSGQRTTAPFRAPESTSATRTETDVM
CCCCCCCCCEEEEEECCCCCCCCHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHE
EIPFAVSSVDTKLIRTVAATRGDDLYDWVAGVARQNNFGGLWDNYAVRGFAGDGGTSGTD
ECCEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCC
YLVNGFSWNRGMSVPRDTATLERMEVLKGPASALYGRGDPGGLISYTTKQPQFAPSNTIG
EEEECCCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCCCCCCCEEEEECCCCCCCCCCEEE
VSAGSYGALRQTLDSTGPVTKSLAYRFIAMNEDNGSFRDTVSSKRYLFAPSFTWDIGDDT
ECCCCHHHHHHHHHCCCCHHHHEEEEEEEEECCCCCHHHHCCCCEEEECCCEEEECCCCC
TLHYEFETARQRAPLDRGVVAVNGQLGAVPASRFMGEPRDGDYDVRNSGHQLTLEHRFNA
EEEEEEHHHHHCCCCCCCEEEECCCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEEEECCC
DWSINAGFAQRDTDLSGRSSEAFALQPDGRTLWRRYRQVAFHSNDLQGRVEVAGKARTGA
CEEECCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCC
IGHMFVMGVDAYRFNYDQFVARSTPTAAAPYAIDIFNPVYGQPAPVPRTATNLLERDDGQ
CEEEEEEECCCEEECHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCC
GLYAQDTLAFGPHWKVLAGLRWDRFHQSVENRLKGVTTSQLQTAVSPRLGIVYEASPSLS
CEEEECCEEECCCCCEEECCCHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCCCEE
LYANTAYSFRPNNGADVNGRAFDPEKGHGYEAGVKWAGTRWLATVAAFYVNKRNVLTADP
EEECCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHCCCCEEEECC
ANAGFSRAAGEVRSRGVEFEWNGELGHGLRGIVNLAYVDAQVTRDSVLTPGARLVDIPRL
CCCCHHHHHHHHHHCCCCEEECCCCCCCHHHHEEEEEEEEECCCCHHCCCCCEEEEECCC
SGSALLMYETALPLVDKAGAGAGVIYVGRRAGNTANTQDGFDLPAYATVQLNGYVQVNKH
CCCEEEEEECCCCHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEEEEEEEECCH
LRASVVLNNLFNRTYYVSSYNSLWVTPGAPRSLFASLSYTF
HHHHHHHHHHHCCEEEEECCCEEEECCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 10103258; 7642488 [H]