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The map label for this gene is gbpR [H]

Identifier: 189354071

GI number: 189354071

Start: 2405413

End: 2406363

Strand: Direct

Name: gbpR [H]

Synonym: BMULJ_05324

Alternate gene names: 189354071

Gene position: 2405413-2406363 (Clockwise)

Preceding gene: 189354059

Following gene: 189354072

Centisome position: 97.26

GC content: 69.93

Gene sequence:

>951_bases
ATGCCCGATGCCAGTCCGTGGGGAAACCGTTCCCGCCTGAAAACCCGCCAGTTGCTGCTCGTCGTCGCGCTTGCCGACGA
GGGCAGCATCCATCGCGCGGCCGCCGCGCTGAACATGACGCAACCCGCTGCCTCGAAGCTGCTGCGCGAGCTGGAGGAGT
CGATCGGCGCGGTGCTGTTCGAGCGGCTGCCGCGCGGGATGCGGCCGACGCTGTACGGCGACGCGCTGATCCGCCACGCG
CGCGCCGCGCTCGGCAGCCTCGATCAGGCGCGCGAGGAACTGGCCGCGCTGAAGTCGGGGCATCTGGGGCACGTCGCCGT
CGGCGCGATCACGTCGCCGGGGTTGCGCATCGTGCCGGCCGCCGTCGCCGACGTGAAGGCGTCGCACGCGAACATCCGCA
TCTCCGTCGAAATCGACACGAGCCTCGCGCTGCTCGAGCACCTCGCGCAAGAAAAGCTCGACATCGTGCTCGGCCGGTTA
TCGGCCGAACACGACAAGCTGCATCTGCGCTACGAGCCGCTGACCGGCGAGCCGGTGGCGGCCGTCGTGCGCACCGGCCA
CCCGCTGCTCGCCGATGCGCCGCTCGCGCTCGCCGACGTGCAGCGCGCCGCGTGGATCGTCCCGCCGGCCGGCAGCGTGC
TGCGCCATCGCTTCGAACTCGTGTTTCAGCGCGCGAGCCTCGCGCCGCCGGCAAACGTCGTGGAGACGGCCGCGCTGCTG
TTCATCACGCAGCTGCTCGAACAGAGCGACATGATTGCCGTGGTCGCCGAAGATGTCGCGCATTACTACGCACGCCACGG
GATCGTCAGCGTGCTGCCGTTGGAGATGGACTGCCGGATGGACGACTTCGGGATCATCACGCGCACCGATCGGCTGCCGT
CGCCGGCGGTGGAGGTGATGACCGATGCGATTCGGGCGGCGGCGCGGCAGGTGTATGGGGTGGGGGTGTAG

Upstream 100 bases:

>100_bases
AGGCGAGATACCGGCGCAGTCTAGGGAGAATTTTGATAACCTACCAATGACGTTTTCGCCGTTTCCCATATCGAATCAGA
TATTGATATAAACCCGTACG

Downstream 100 bases:

>100_bases
GGTGTGAGGGCCGGCGGGTTGAGGGGCGCCGCCGACGATGCTCACGCCGCCCGCCGACACCAGGCGCCCTTCGCTCAGCG
TCATCGTCTGATCAATCCCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MPDASPWGNRSRLKTRQLLLVVALADEGSIHRAAAALNMTQPAASKLLRELEESIGAVLFERLPRGMRPTLYGDALIRHA
RAALGSLDQAREELAALKSGHLGHVAVGAITSPGLRIVPAAVADVKASHANIRISVEIDTSLALLEHLAQEKLDIVLGRL
SAEHDKLHLRYEPLTGEPVAAVVRTGHPLLADAPLALADVQRAAWIVPPAGSVLRHRFELVFQRASLAPPANVVETAALL
FITQLLEQSDMIAVVAEDVAHYYARHGIVSVLPLEMDCRMDDFGIITRTDRLPSPAVEVMTDAIRAAARQVYGVGV

Sequences:

>Translated_316_residues
MPDASPWGNRSRLKTRQLLLVVALADEGSIHRAAAALNMTQPAASKLLRELEESIGAVLFERLPRGMRPTLYGDALIRHA
RAALGSLDQAREELAALKSGHLGHVAVGAITSPGLRIVPAAVADVKASHANIRISVEIDTSLALLEHLAQEKLDIVLGRL
SAEHDKLHLRYEPLTGEPVAAVVRTGHPLLADAPLALADVQRAAWIVPPAGSVLRHRFELVFQRASLAPPANVVETAALL
FITQLLEQSDMIAVVAEDVAHYYARHGIVSVLPLEMDCRMDDFGIITRTDRLPSPAVEVMTDAIRAAARQVYGVGV
>Mature_315_residues
PDASPWGNRSRLKTRQLLLVVALADEGSIHRAAAALNMTQPAASKLLRELEESIGAVLFERLPRGMRPTLYGDALIRHAR
AALGSLDQAREELAALKSGHLGHVAVGAITSPGLRIVPAAVADVKASHANIRISVEIDTSLALLEHLAQEKLDIVLGRLS
AEHDKLHLRYEPLTGEPVAAVVRTGHPLLADAPLALADVQRAAWIVPPAGSVLRHRFELVFQRASLAPPANVVETAALLF
ITQLLEQSDMIAVVAEDVAHYYARHGIVSVLPLEMDCRMDDFGIITRTDRLPSPAVEVMTDAIRAAARQVYGVGV

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081904, Length=296, Percent_Identity=30.7432432432432, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787601, Length=268, Percent_Identity=26.865671641791, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI145693105, Length=169, Percent_Identity=25.4437869822485, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI157672245, Length=240, Percent_Identity=27.9166666666667, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789506, Length=265, Percent_Identity=23.0188679245283, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787879, Length=220, Percent_Identity=26.3636363636364, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34033; Mature: 33902

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50931 HTH_LYSR ; PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDASPWGNRSRLKTRQLLLVVALADEGSIHRAAAALNMTQPAASKLLRELEESIGAVLF
CCCCCCCCCHHHHHHEEEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ERLPRGMRPTLYGDALIRHARAALGSLDQAREELAALKSGHLGHVAVGAITSPGLRIVPA
HHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEHH
AVADVKASHANIRISVEIDTSLALLEHLAQEKLDIVLGRLSAEHDKLHLRYEPLTGEPVA
HHHHHHCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHH
AVVRTGHPLLADAPLALADVQRAAWIVPPAGSVLRHRFELVFQRASLAPPANVVETAALL
HHHHCCCCCCCCCCHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
FITQLLEQSDMIAVVAEDVAHYYARHGIVSVLPLEMDCRMDDFGIITRTDRLPSPAVEVM
HHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEECEEECCCCCCCCEEEECCCCCCHHHHHH
TDAIRAAARQVYGVGV
HHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PDASPWGNRSRLKTRQLLLVVALADEGSIHRAAAALNMTQPAASKLLRELEESIGAVLF
CCCCCCCCHHHHHHEEEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ERLPRGMRPTLYGDALIRHARAALGSLDQAREELAALKSGHLGHVAVGAITSPGLRIVPA
HHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEHH
AVADVKASHANIRISVEIDTSLALLEHLAQEKLDIVLGRLSAEHDKLHLRYEPLTGEPVA
HHHHHHCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHH
AVVRTGHPLLADAPLALADVQRAAWIVPPAGSVLRHRFELVFQRASLAPPANVVETAALL
HHHHCCCCCCCCCCHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
FITQLLEQSDMIAVVAEDVAHYYARHGIVSVLPLEMDCRMDDFGIITRTDRLPSPAVEVM
HHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEECEEECCCCCCCCEEEECCCCCCHHHHHH
TDAIRAAARQVYGVGV
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]