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The map label for this gene is catA [H]

Identifier: 189354035

GI number: 189354035

Start: 2363552

End: 2364487

Strand: Reverse

Name: catA [H]

Synonym: BMULJ_05288

Alternate gene names: 189354035

Gene position: 2364487-2363552 (Counterclockwise)

Preceding gene: 189354036

Following gene: 189354034

Centisome position: 95.61

GC content: 67.52

Gene sequence:

>936_bases
ATGAGCGTCAAGGTATTCGATACGAAGGAAGTGCAGGATCTGCTGAAGGCCGCCGCGAACCTGAACGGCGACGCCGGCAA
CGCGCGCTTTCGCCAGATCGTGCATCGTCTGCTGAGCGACCTGTTCAAGGCGATCGACGATCTCGACATCACGCCCGACG
AAGTCTGGGCCGGCGTCAACTATCTGAACAAGCTCGGCCAGGACGGCGAAGCGGCGCTGCTCGCGGCGGGCATCGGGCTC
GAGAAGTATCTGGACATCCGGATGGATGCGGCCGACCGCGCGGCCGGCCTCGACGGCGGCACGCCGCGCACGATCGAAGG
GCCGCTGTACGTCGCAGGCGCGCCGGTGCGCGACGGCGTCGCGAAGATCGATCTCGACGACGATGCCGACGCGGGCCCGC
TCGTGATCCGCGGCACCGTGACGGGCACCGACGGCAAGCCGCTCGCCGGTGCGCTCGTCGAATGCTGGCACGCGAATTCG
AAGGGCTTCTACTCGCACTTCGACCCGACCGGCGCGCAGACCGCGTTCAACCTGCGCGGCGCGGTGCGCACCGATGCCAA
CGGCAAGTACGAATTCCGCACGCTGATGCCGGTCGGCTACGGCTGCCCGCCGCAAGGCGCGACGCAGCAGCTGCTGAACG
GGCTCGGCCGCCACGGCAACCGGCCGGCGCACGTGCACTTCTTCGTGTCCGGCGACGGCCATCGCAAGCTGACCACGCAG
TTCAACATCGAAGGCGACCCGCTGATCTGGGACGACTTCGCATACGCGACGCGCGAGGAACTGATTCCGCACGTGGTCGA
CAAGACCGGCGGCGCCGCGCTCGGCATGAAGAGCGATGCGTACAAGGAAATCGAGTTCGACATCGTGCTGACGCCGCTGC
TCGACGGCCGCGACAACCAGGTCGTCCATCGTCCGCGCGCGTCCGCCGACGCGTAA

Upstream 100 bases:

>100_bases
GCCACCCGTCGTCGGTTCGCGAAGACGACGTCTGAGCCGGCCGCGCGATGCCGCGCGAGCGCCGGTCGATTTTTCCTAAA
ACACACGTGGAGACACCATC

Downstream 100 bases:

>100_bases
CGCCCCGGCGCCGCGGCGGCGCTGCGCCGCGCGGCTCCCGCGCCCCCTCTTTCGACACCGATGCACGCCGGCGCGTGCAT
GGGAGGAACCACCATGTCCG

Product: catechol 1,2-dioxygenase

Products: NA

Alternate protein names: 1,2-CTD 1; CDI1 [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSVKVFDTKEVQDLLKAAANLNGDAGNARFRQIVHRLLSDLFKAIDDLDITPDEVWAGVNYLNKLGQDGEAALLAAGIGL
EKYLDIRMDAADRAAGLDGGTPRTIEGPLYVAGAPVRDGVAKIDLDDDADAGPLVIRGTVTGTDGKPLAGALVECWHANS
KGFYSHFDPTGAQTAFNLRGAVRTDANGKYEFRTLMPVGYGCPPQGATQQLLNGLGRHGNRPAHVHFFVSGDGHRKLTTQ
FNIEGDPLIWDDFAYATREELIPHVVDKTGGAALGMKSDAYKEIEFDIVLTPLLDGRDNQVVHRPRASADA

Sequences:

>Translated_311_residues
MSVKVFDTKEVQDLLKAAANLNGDAGNARFRQIVHRLLSDLFKAIDDLDITPDEVWAGVNYLNKLGQDGEAALLAAGIGL
EKYLDIRMDAADRAAGLDGGTPRTIEGPLYVAGAPVRDGVAKIDLDDDADAGPLVIRGTVTGTDGKPLAGALVECWHANS
KGFYSHFDPTGAQTAFNLRGAVRTDANGKYEFRTLMPVGYGCPPQGATQQLLNGLGRHGNRPAHVHFFVSGDGHRKLTTQ
FNIEGDPLIWDDFAYATREELIPHVVDKTGGAALGMKSDAYKEIEFDIVLTPLLDGRDNQVVHRPRASADA
>Mature_310_residues
SVKVFDTKEVQDLLKAAANLNGDAGNARFRQIVHRLLSDLFKAIDDLDITPDEVWAGVNYLNKLGQDGEAALLAAGIGLE
KYLDIRMDAADRAAGLDGGTPRTIEGPLYVAGAPVRDGVAKIDLDDDADAGPLVIRGTVTGTDGKPLAGALVECWHANSK
GFYSHFDPTGAQTAFNLRGAVRTDANGKYEFRTLMPVGYGCPPQGATQQLLNGLGRHGNRPAHVHFFVSGDGHRKLTTQF
NIEGDPLIWDDFAYATREELIPHVVDKTGGAALGMKSDAYKEIEFDIVLTPLLDGRDNQVVHRPRASADA

Specific function: Can cleave 4-methyl-, 4-chloro-, and 3-methoxycatechol at lower rates than catechol, but has no activity with 4- nitrocatechol or protocatechuic acid [H]

COG id: COG3485

COG function: function code Q; Protocatechuate 3,4-dioxygenase beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the intradiol ring-cleavage dioxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007535
- InterPro:   IPR012801
- InterPro:   IPR000627
- InterPro:   IPR015889 [H]

Pfam domain/function: PF00775 Dioxygenase_C; PF04444 Dioxygenase_N [H]

EC number: =1.13.11.1 [H]

Molecular weight: Translated: 33447; Mature: 33316

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00083 INTRADIOL_DIOXYGENAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKVFDTKEVQDLLKAAANLNGDAGNARFRQIVHRLLSDLFKAIDDLDITPDEVWAGVN
CCEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
YLNKLGQDGEAALLAAGIGLEKYLDIRMDAADRAAGLDGGTPRTIEGPLYVAGAPVRDGV
HHHHHCCCCCEEEEEECCCHHHHHEEEECCHHHHCCCCCCCCCEECCCEEEECCCCCCCE
AKIDLDDDADAGPLVIRGTVTGTDGKPLAGALVECWHANSKGFYSHFDPTGAQTAFNLRG
EEEECCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCC
AVRTDANGKYEFRTLMPVGYGCPPQGATQQLLNGLGRHGNRPAHVHFFVSGDGHRKLTTQ
EEEECCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEE
FNIEGDPLIWDDFAYATREELIPHVVDKTGGAALGMKSDAYKEIEFDIVLTPLLDGRDNQ
EECCCCCEEECCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEEEEECCCCCCCC
VVHRPRASADA
EEECCCCCCCC
>Mature Secondary Structure 
SVKVFDTKEVQDLLKAAANLNGDAGNARFRQIVHRLLSDLFKAIDDLDITPDEVWAGVN
CEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
YLNKLGQDGEAALLAAGIGLEKYLDIRMDAADRAAGLDGGTPRTIEGPLYVAGAPVRDGV
HHHHHCCCCCEEEEEECCCHHHHHEEEECCHHHHCCCCCCCCCEECCCEEEECCCCCCCE
AKIDLDDDADAGPLVIRGTVTGTDGKPLAGALVECWHANSKGFYSHFDPTGAQTAFNLRG
EEEECCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCC
AVRTDANGKYEFRTLMPVGYGCPPQGATQQLLNGLGRHGNRPAHVHFFVSGDGHRKLTTQ
EEEECCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEE
FNIEGDPLIWDDFAYATREELIPHVVDKTGGAALGMKSDAYKEIEFDIVLTPLLDGRDNQ
EECCCCCEEECCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEEEEECCCCCCCC
VVHRPRASADA
EEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9260969; 9473520 [H]