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The map label for this gene is catR [H]

Identifier: 189354028

GI number: 189354028

Start: 2356887

End: 2357837

Strand: Direct

Name: catR [H]

Synonym: BMULJ_05281

Alternate gene names: 189354028

Gene position: 2356887-2357837 (Clockwise)

Preceding gene: 189354024

Following gene: 189354042

Centisome position: 95.3

GC content: 65.3

Gene sequence:

>951_bases
ATGGAGCTACGCCATCTGCGGTATTTCGTTGCGGTCGCCGAAGAACGCAGCTTCACGCGCGCCGCGCAACGCCTGCATAT
CGCGCAGCCGCCGTTGAGCCGGCAGATCCAGCAGCTCGAACAGCTGCTCGACGTGCAGCTGTTCGAGCGCAATTCGCGCC
CGCTCAAGCTCACGGAGACGGGGCGCTTCTTCTATCAGCATGCGGCGCAGCTGCTCGCGCAAACCGCCGAACTCGAATCG
ATGACGCGCCGCGTCGGCAAGATCGAGCGCAGCCTGTCGGTCGGCTTCGTCGGCTCGACGCTGTACGGGATGCTGCCGAA
GATCATCCGCCGCTATCGCCAGCAATACGCGGAAGTCGAGCTGAGCCTGCACGAGATGTCGACGATGGATCAGATCAAGG
CGCTGAAGGAAGGCCGGATCGACGTCGGCTTCGGCCGCATCCGTCTCGAGGATCCGAGCATTCGGCGCGTCGTGCTGCGC
GAGGAGCGGCTGATCGCGGCGCTGCCGCTCGGCCATCCGCTCTGCGACGCGAAGCCGGTGCTGTCGCTGCACGACCTGCT
GAAGGAAACGCTGATCATCTTCCCGAAGGCGCCGCGGCCGAGCTATGCCGATCAGGTGCTCGCGGCGTTCCACGACCGTT
CGCTGAAACCGGCGCGCGTGATCGAGACGCGCGAGCTGCAGATCGCGCTCGGGCTCGTCGCGGCCGGCGAAGGCGTGTCG
ATCGTGCCGAAGAGCGTGTACGGGCTGAAGCGCGACGACATCGCCTACAAGGATCTCGACGACGCGAAGCTCGTGTCGCC
GATCATCATGAGCATGCGGATGCTCGACCAGTCCGAAGACATCGAACGCATGCTGCAGCTGATCTACGATCTGTACGACG
AGCAGGGCATGGAATACATGACGCCGTCGGAGCACGAACCGACGGCGCGGCGCGGGCCGGCGCCGGACTGA

Upstream 100 bases:

>100_bases
ATCGGATGCGCTGCGCGTCCCGTAAAATACGACATCGGCCGGCGCGCGACGCGCGTTCGCGCCGGCTTGCGCAACGCCCC
ACTCTTCGACGGCAGGAACC

Downstream 100 bases:

>100_bases
ACGGGCCGACGCCCGTTCGCGTCGTCAGCGGTTCGCCGCCGCGAGATCGGCGCCCGGCGTGCGGCCGGGACGCAGCCCGA
ACGCGGCGAGCGCGGCGCCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Ben and cat operon transcriptional regulator [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MELRHLRYFVAVAEERSFTRAAQRLHIAQPPLSRQIQQLEQLLDVQLFERNSRPLKLTETGRFFYQHAAQLLAQTAELES
MTRRVGKIERSLSVGFVGSTLYGMLPKIIRRYRQQYAEVELSLHEMSTMDQIKALKEGRIDVGFGRIRLEDPSIRRVVLR
EERLIAALPLGHPLCDAKPVLSLHDLLKETLIIFPKAPRPSYADQVLAAFHDRSLKPARVIETRELQIALGLVAAGEGVS
IVPKSVYGLKRDDIAYKDLDDAKLVSPIIMSMRMLDQSEDIERMLQLIYDLYDEQGMEYMTPSEHEPTARRGPAPD

Sequences:

>Translated_316_residues
MELRHLRYFVAVAEERSFTRAAQRLHIAQPPLSRQIQQLEQLLDVQLFERNSRPLKLTETGRFFYQHAAQLLAQTAELES
MTRRVGKIERSLSVGFVGSTLYGMLPKIIRRYRQQYAEVELSLHEMSTMDQIKALKEGRIDVGFGRIRLEDPSIRRVVLR
EERLIAALPLGHPLCDAKPVLSLHDLLKETLIIFPKAPRPSYADQVLAAFHDRSLKPARVIETRELQIALGLVAAGEGVS
IVPKSVYGLKRDDIAYKDLDDAKLVSPIIMSMRMLDQSEDIERMLQLIYDLYDEQGMEYMTPSEHEPTARRGPAPD
>Mature_316_residues
MELRHLRYFVAVAEERSFTRAAQRLHIAQPPLSRQIQQLEQLLDVQLFERNSRPLKLTETGRFFYQHAAQLLAQTAELES
MTRRVGKIERSLSVGFVGSTLYGMLPKIIRRYRQQYAEVELSLHEMSTMDQIKALKEGRIDVGFGRIRLEDPSIRRVVLR
EERLIAALPLGHPLCDAKPVLSLHDLLKETLIIFPKAPRPSYADQVLAAFHDRSLKPARVIETRELQIALGLVAAGEGVS
IVPKSVYGLKRDDIAYKDLDDAKLVSPIIMSMRMLDQSEDIERMLQLIYDLYDEQGMEYMTPSEHEPTARRGPAPD

Specific function: Positive regulator of the ben and cat genes for benzoate degradation. BenM is necessary for ben gene expression but not for expression of the cat genes, which can be regulated by CatM. Binds to the inducers cis,cis-muconate and benzoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=268, Percent_Identity=35.8208955223881, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1788887, Length=257, Percent_Identity=32.6848249027237, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI2367136, Length=262, Percent_Identity=29.3893129770992, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87081904, Length=264, Percent_Identity=30.6818181818182, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI145693105, Length=302, Percent_Identity=27.1523178807947, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1790399, Length=259, Percent_Identity=28.957528957529, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI157672245, Length=257, Percent_Identity=29.5719844357977, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787601, Length=247, Percent_Identity=27.9352226720648, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787806, Length=248, Percent_Identity=26.6129032258064, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788297, Length=129, Percent_Identity=34.8837209302326, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788481, Length=144, Percent_Identity=32.6388888888889, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788748, Length=316, Percent_Identity=24.3670886075949, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082132, Length=246, Percent_Identity=28.8617886178862, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786401, Length=167, Percent_Identity=33.5329341317365, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790208, Length=146, Percent_Identity=32.8767123287671, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790262, Length=195, Percent_Identity=27.6923076923077, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789204, Length=243, Percent_Identity=25.5144032921811, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790783, Length=146, Percent_Identity=28.0821917808219, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI145693193, Length=129, Percent_Identity=34.1085271317829, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1789173, Length=195, Percent_Identity=29.7435897435897, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787530, Length=247, Percent_Identity=23.0769230769231, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36158; Mature: 36158

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRHLRYFVAVAEERSFTRAAQRLHIAQPPLSRQIQQLEQLLDVQLFERNSRPLKLTET
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHH
GRFFYQHAAQLLAQTAELESMTRRVGKIERSLSVGFVGSTLYGMLPKIIRRYRQQYAEVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSLHEMSTMDQIKALKEGRIDVGFGRIRLEDPSIRRVVLREERLIAALPLGHPLCDAKPV
HHHHHHHHHHHHHHHHCCCEEECCCEEEECCCHHHHHHHHHHHHHEECCCCCCCCCCCHH
LSLHDLLKETLIIFPKAPRPSYADQVLAAFHDRSLKPARVIETRELQIALGLVAAGEGVS
HHHHHHHHHHHEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHEEEEEEEECCCCCE
IVPKSVYGLKRDDIAYKDLDDAKLVSPIIMSMRMLDQSEDIERMLQLIYDLYDEQGMEYM
ECCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC
TPSEHEPTARRGPAPD
CCCCCCCCCCCCCCCC
>Mature Secondary Structure
MELRHLRYFVAVAEERSFTRAAQRLHIAQPPLSRQIQQLEQLLDVQLFERNSRPLKLTET
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHH
GRFFYQHAAQLLAQTAELESMTRRVGKIERSLSVGFVGSTLYGMLPKIIRRYRQQYAEVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSLHEMSTMDQIKALKEGRIDVGFGRIRLEDPSIRRVVLREERLIAALPLGHPLCDAKPV
HHHHHHHHHHHHHHHHCCCEEECCCEEEECCCHHHHHHHHHHHHHEECCCCCCCCCCCHH
LSLHDLLKETLIIFPKAPRPSYADQVLAAFHDRSLKPARVIETRELQIALGLVAAGEGVS
HHHHHHHHHHHEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHEEEEEEEECCCCCE
IVPKSVYGLKRDDIAYKDLDDAKLVSPIIMSMRMLDQSEDIERMLQLIYDLYDEQGMEYM
ECCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC
TPSEHEPTARRGPAPD
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9573203 [H]