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The map label for this gene is rstB [H]

Identifier: 189353809

GI number: 189353809

Start: 2103628

End: 2104956

Strand: Reverse

Name: rstB [H]

Synonym: BMULJ_05056

Alternate gene names: 189353809

Gene position: 2104956-2103628 (Counterclockwise)

Preceding gene: 189353810

Following gene: 189353806

Centisome position: 85.11

GC content: 69.98

Gene sequence:

>1329_bases
GTGAACGCGCGCATCGCGTGGCACTGGCCGCGCTCGCTGTTCGCACGGCTCGCGCTGATTCTCTGCGTGGGGCTCGCGCT
CGCGCAGACGCTGTCGTTCTGGCTCACCGTCACCGAGCGCGATCAGGCGACGACCAACCTGATGATGGGCTACATCGAGC
GTGAAGTCGCGAGCTCGGTCGCGCTGCTCGATCATCTGCCGCCCGACGAGCGTGCCGCGTGGCTGCCGCGTCTCGCACGA
CGCAGCTATGCGTTCATCCTCGGGCCCGGCGAGACCGGCACGCCGCCGGAGGCGCGGCTGTCGGCACGCGTCGAGCGGTC
GATCTCGGACGGTATCGGCGGCCGGTATCCGCTGACCGCGAACGCGATTCCGGGCGATCGCGAACATCTGCAAGTGCATC
TGCGGCTGACCGACGGCTCGCCGCTCACGATCGACATTCATCCGATGTCGACGGTGCCGCTGTCCGACTGGCTGCCGGTC
GTGCTCGCGCTGCAGCTCGCGGTGCTGGCCGCATGCTGCTGGCTCGCGGTACGGCTCGCGACGCGGCCGCTGAAGCAGCT
CGCACTCGCGGCCGACGCGCTCGGCCCCGACCTGAAAGGCGAGCGGCTCAGCGAGGACGGGCCGTCCGAAGTCGCACGCG
CGGCGCGCGCATTCAACGCGATGCAGGATCGCATCGCGCAGTACATGACCGAACGGATGCAGATCCTCGCGTCGATCTCG
CACGATCTGCAGACGCCGATCACGCGGATGCGGCTGCGTGTCGACGTGATGGACGACGACGCGCAAGGCGCGAAGCTGCG
GCAGGACCTGCTCGAGATGGAGCATCTGGTGAAGGAGGGCGTCGCGTATGCGCGTACGCTGCACGGCTCCGACGAGGCGG
CGCGCCGCATCGATCTCGATGCGCTGCTCGACAGCATCGTCTGCGATTACGTCGATGCAGGGCAGGACGTCGCGCTGCAC
AGCCGCGCGCCGCTTGCGCTCGTCACGCGGCCGAAGGCGCTGCGCCGGATCGTCGGCAATCTCGTCGACAACGCGCTGAA
GTTCGCGGGCGCGGCGGAGATCGACGTGCAGCCGGCGCCGGACGGCGGCGCGGTGATCGTCGTGCGCGACCGCGGGCCCG
GCATTCCGGACGATCAGCTCGACGCGGTGTTCGAACCGTTCCGCCGCGTGGAGACGTCGCGCAATCGCGAAACGGGCGGC
ACGGGCCTTGGCCTCGCGATCGCGCGCCAGCTCGCGCTCGCGATGGGCGGCACGCTGACGCTGAGCAATCGACAGGACGG
CGGCGGTGGGCTCGATGCGCGTCTGACGCTCGTCAATGCGGCGGCGTAG

Upstream 100 bases:

>100_bases
AGCGGCTGCGCGACGGCGCGCGCGAACCGCGCTACATCAAGACGCTGCGCAACGAAGGCTACGTGTTCTCGTCGGCCGTC
ACCGCGATCGAAGGCACATC

Downstream 100 bases:

>100_bases
CAAAGGCATGGCGTGTGGCCGGCCGCTTTAGCGTTCGGGCGCGGCAGGGCCGCGCCGCGCGTGCGGGAACAGATGCGCGA
TAGCCCTTCCGATAGCGTGC

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MNARIAWHWPRSLFARLALILCVGLALAQTLSFWLTVTERDQATTNLMMGYIEREVASSVALLDHLPPDERAAWLPRLAR
RSYAFILGPGETGTPPEARLSARVERSISDGIGGRYPLTANAIPGDREHLQVHLRLTDGSPLTIDIHPMSTVPLSDWLPV
VLALQLAVLAACCWLAVRLATRPLKQLALAADALGPDLKGERLSEDGPSEVARAARAFNAMQDRIAQYMTERMQILASIS
HDLQTPITRMRLRVDVMDDDAQGAKLRQDLLEMEHLVKEGVAYARTLHGSDEAARRIDLDALLDSIVCDYVDAGQDVALH
SRAPLALVTRPKALRRIVGNLVDNALKFAGAAEIDVQPAPDGGAVIVVRDRGPGIPDDQLDAVFEPFRRVETSRNRETGG
TGLGLAIARQLALAMGGTLTLSNRQDGGGGLDARLTLVNAAA

Sequences:

>Translated_442_residues
MNARIAWHWPRSLFARLALILCVGLALAQTLSFWLTVTERDQATTNLMMGYIEREVASSVALLDHLPPDERAAWLPRLAR
RSYAFILGPGETGTPPEARLSARVERSISDGIGGRYPLTANAIPGDREHLQVHLRLTDGSPLTIDIHPMSTVPLSDWLPV
VLALQLAVLAACCWLAVRLATRPLKQLALAADALGPDLKGERLSEDGPSEVARAARAFNAMQDRIAQYMTERMQILASIS
HDLQTPITRMRLRVDVMDDDAQGAKLRQDLLEMEHLVKEGVAYARTLHGSDEAARRIDLDALLDSIVCDYVDAGQDVALH
SRAPLALVTRPKALRRIVGNLVDNALKFAGAAEIDVQPAPDGGAVIVVRDRGPGIPDDQLDAVFEPFRRVETSRNRETGG
TGLGLAIARQLALAMGGTLTLSNRQDGGGGLDARLTLVNAAA
>Mature_442_residues
MNARIAWHWPRSLFARLALILCVGLALAQTLSFWLTVTERDQATTNLMMGYIEREVASSVALLDHLPPDERAAWLPRLAR
RSYAFILGPGETGTPPEARLSARVERSISDGIGGRYPLTANAIPGDREHLQVHLRLTDGSPLTIDIHPMSTVPLSDWLPV
VLALQLAVLAACCWLAVRLATRPLKQLALAADALGPDLKGERLSEDGPSEVARAARAFNAMQDRIAQYMTERMQILASIS
HDLQTPITRMRLRVDVMDDDAQGAKLRQDLLEMEHLVKEGVAYARTLHGSDEAARRIDLDALLDSIVCDYVDAGQDVALH
SRAPLALVTRPKALRRIVGNLVDNALKFAGAAEIDVQPAPDGGAVIVVRDRGPGIPDDQLDAVFEPFRRVETSRNRETGG
TGLGLAIARQLALAMGGTLTLSNRQDGGGGLDARLTLVNAAA

Specific function: Member of the two-component regulatory system rstB/rstA. RstB functions as a membrane-associated protein kinase that phosphorylates rstA (Potential) [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=281, Percent_Identity=31.6725978647687, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1789808, Length=301, Percent_Identity=31.5614617940199, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1790346, Length=237, Percent_Identity=29.1139240506329, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1786912, Length=233, Percent_Identity=32.618025751073, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87082128, Length=281, Percent_Identity=25.6227758007117, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788393, Length=273, Percent_Identity=26.7399267399267, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI48994928, Length=241, Percent_Identity=28.2157676348548, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786783, Length=314, Percent_Identity=24.5222929936306, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1790551, Length=283, Percent_Identity=25.7950530035336, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787374, Length=309, Percent_Identity=24.5954692556634, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI145693157, Length=260, Percent_Identity=25.3846153846154, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87081816, Length=120, Percent_Identity=39.1666666666667, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789149, Length=224, Percent_Identity=28.125, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790861, Length=288, Percent_Identity=25, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1789403, Length=287, Percent_Identity=27.5261324041812, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1786600, Length=199, Percent_Identity=29.1457286432161, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47907; Mature: 47907

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNARIAWHWPRSLFARLALILCVGLALAQTLSFWLTVTERDQATTNLMMGYIEREVASSV
CCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHH
ALLDHLPPDERAAWLPRLARRSYAFILGPGETGTPPEARLSARVERSISDGIGGRYPLTA
HHHHCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEC
NAIPGDREHLQVHLRLTDGSPLTIDIHPMSTVPLSDWLPVVLALQLAVLAACCWLAVRLA
CCCCCCCCEEEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRPLKQLALAADALGPDLKGERLSEDGPSEVARAARAFNAMQDRIAQYMTERMQILASIS
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDLQTPITRMRLRVDVMDDDAQGAKLRQDLLEMEHLVKEGVAYARTLHGSDEAARRIDLD
HHHHCHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ALLDSIVCDYVDAGQDVALHSRAPLALVTRPKALRRIVGNLVDNALKFAGAAEIDVQPAP
HHHHHHHHHHHCCCCCEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECC
DGGAVIVVRDRGPGIPDDQLDAVFEPFRRVETSRNRETGGTGLGLAIARQLALAMGGTLT
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCEEE
LSNRQDGGGGLDARLTLVNAAA
ECCCCCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MNARIAWHWPRSLFARLALILCVGLALAQTLSFWLTVTERDQATTNLMMGYIEREVASSV
CCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHH
ALLDHLPPDERAAWLPRLARRSYAFILGPGETGTPPEARLSARVERSISDGIGGRYPLTA
HHHHCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEC
NAIPGDREHLQVHLRLTDGSPLTIDIHPMSTVPLSDWLPVVLALQLAVLAACCWLAVRLA
CCCCCCCCEEEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRPLKQLALAADALGPDLKGERLSEDGPSEVARAARAFNAMQDRIAQYMTERMQILASIS
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDLQTPITRMRLRVDVMDDDAQGAKLRQDLLEMEHLVKEGVAYARTLHGSDEAARRIDLD
HHHHCHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ALLDSIVCDYVDAGQDVALHSRAPLALVTRPKALRRIVGNLVDNALKFAGAAEIDVQPAP
HHHHHHHHHHHCCCCCEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECC
DGGAVIVVRDRGPGIPDDQLDAVFEPFRRVETSRNRETGGTGLGLAIARQLALAMGGTLT
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCEEE
LSNRQDGGGGLDARLTLVNAAA
ECCCCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2646639; 1925016; 1495392 [H]