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The map label for this gene is ompR [H]

Identifier: 189353810

GI number: 189353810

Start: 2104953

End: 2105693

Strand: Reverse

Name: ompR [H]

Synonym: BMULJ_05057

Alternate gene names: 189353810

Gene position: 2105693-2104953 (Counterclockwise)

Preceding gene: 189353812

Following gene: 189353809

Centisome position: 85.14

GC content: 67.88

Gene sequence:

>741_bases
ATGGACAAGCCCGACCACGTGCTGATCGTCGACGACGATCGCGCCATTCGCGAACTGATCGCGGACTATCTCGAGAAGAA
CGGCATGCGCGTGTCGCTGGCCGCGAACGGGCGCGAGATGCGCAGCGTGCTCGACGACGGCGCGCCCGACCTGATCGTGC
TCGACCTGATGCTGCCGGGCGAGGACGGCCTGACGCTGTGCCGCGATCTGCGCGCCGGCAAGTTCCGTACGGTGCCGGTG
CTGATGCTGACCGCGCGCAGCGAGGAAACCGACCGGATCGTCGGCCTCGAAATGGGTGCGGACGACTACCTCGCGAAGCC
GTTCGCGGTACGCGAACTGCTCGCGCGGATCCGTTCGGTGCTGCGCCGCGCGCGGATGCTGCCGCCCGGCATGCAGGTGA
CGGAGACGGCCGGCATGCTCGCGTTCGGCGAATGGCGGCTCGACACGACGGGGCGCCATCTGCTCGATGCGGAAGGCACG
CTCGTCGCGCTGAGCGGCGCCGAATATCGGCTGTTGCGCGTGTTTCTCGATCATCCGCAGCGCGTGCTGACGCGCGATCA
GTTGCTGAATCTGACGCAGGGCCGCCAGTCGGATCCCTTCGACCGTTCGATCGACCTGCTCGTGAGCCGGCTGCGCCAGC
GGCTGCGCGACGGCGCGCGCGAACCGCGCTACATCAAGACGCTGCGCAACGAAGGCTACGTGTTCTCGTCGGCCGTCACC
GCGATCGAAGGCACATCGTGA

Upstream 100 bases:

>100_bases
CGCAGCGGCGGCGCGATACAGTGCGATACAAACGCGCCGGTTCGCCGCGGTATAAAGGCGGACATCGCCCCGCCGCCCTT
CACGAGTACGACACCGATCC

Downstream 100 bases:

>100_bases
ACGCGCGCATCGCGTGGCACTGGCCGCGCTCGCTGTTCGCACGGCTCGCGCTGATTCTCTGCGTGGGGCTCGCGCTCGCG
CAGACGCTGTCGTTCTGGCT

Product: OmpR family two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MDKPDHVLIVDDDRAIRELIADYLEKNGMRVSLAANGREMRSVLDDGAPDLIVLDLMLPGEDGLTLCRDLRAGKFRTVPV
LMLTARSEETDRIVGLEMGADDYLAKPFAVRELLARIRSVLRRARMLPPGMQVTETAGMLAFGEWRLDTTGRHLLDAEGT
LVALSGAEYRLLRVFLDHPQRVLTRDQLLNLTQGRQSDPFDRSIDLLVSRLRQRLRDGAREPRYIKTLRNEGYVFSSAVT
AIEGTS

Sequences:

>Translated_246_residues
MDKPDHVLIVDDDRAIRELIADYLEKNGMRVSLAANGREMRSVLDDGAPDLIVLDLMLPGEDGLTLCRDLRAGKFRTVPV
LMLTARSEETDRIVGLEMGADDYLAKPFAVRELLARIRSVLRRARMLPPGMQVTETAGMLAFGEWRLDTTGRHLLDAEGT
LVALSGAEYRLLRVFLDHPQRVLTRDQLLNLTQGRQSDPFDRSIDLLVSRLRQRLRDGAREPRYIKTLRNEGYVFSSAVT
AIEGTS
>Mature_246_residues
MDKPDHVLIVDDDRAIRELIADYLEKNGMRVSLAANGREMRSVLDDGAPDLIVLDLMLPGEDGLTLCRDLRAGKFRTVPV
LMLTARSEETDRIVGLEMGADDYLAKPFAVRELLARIRSVLRRARMLPPGMQVTETAGMLAFGEWRLDTTGRHLLDAEGT
LVALSGAEYRLLRVFLDHPQRVLTRDQLLNLTQGRQSDPFDRSIDLLVSRLRQRLRDGAREPRYIKTLRNEGYVFSSAVT
AIEGTS

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=45.1063829787234, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=40.948275862069, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=35.1694915254237, Blast_Score=153, Evalue=8e-39,
Organism=Escherichia coli, GI1788394, Length=238, Percent_Identity=36.5546218487395, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=38.034188034188, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1787229, Length=241, Percent_Identity=36.0995850622407, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1786911, Length=232, Percent_Identity=39.6551724137931, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=38.8888888888889, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=34.9344978165939, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=36.7965367965368, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1787375, Length=234, Percent_Identity=30.3418803418803, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87082012, Length=231, Percent_Identity=31.6017316017316, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=34.061135371179, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1789402, Length=231, Percent_Identity=30.7359307359307, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1788550, Length=113, Percent_Identity=32.7433628318584, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788191, Length=127, Percent_Identity=29.9212598425197, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=104, Percent_Identity=33.6538461538462, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27687; Mature: 27687

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKPDHVLIVDDDRAIRELIADYLEKNGMRVSLAANGREMRSVLDDGAPDLIVLDLMLPG
CCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCEEEEEEEECC
EDGLTLCRDLRAGKFRTVPVLMLTARSEETDRIVGLEMGADDYLAKPFAVRELLARIRSV
CCCHHHHHHHCCCCEEEEEEEEEEECCCCCCEEEEEEECCCHHHCCHHHHHHHHHHHHHH
LRRARMLPPGMQVTETAGMLAFGEWRLDTTGRHLLDAEGTLVALSGAEYRLLRVFLDHPQ
HHHHHCCCCCCCHHHHCCEEEEEEEEECCCCCEEECCCCCEEEECCCCHHHHHHHHHCCH
RVLTRDQLLNLTQGRQSDPFDRSIDLLVSRLRQRLRDGAREPRYIKTLRNEGYVFSSAVT
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEHHHH
AIEGTS
HCCCCC
>Mature Secondary Structure
MDKPDHVLIVDDDRAIRELIADYLEKNGMRVSLAANGREMRSVLDDGAPDLIVLDLMLPG
CCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCEEEEEEEECC
EDGLTLCRDLRAGKFRTVPVLMLTARSEETDRIVGLEMGADDYLAKPFAVRELLARIRSV
CCCHHHHHHHCCCCEEEEEEEEEEECCCCCCEEEEEEECCCHHHCCHHHHHHHHHHHHHH
LRRARMLPPGMQVTETAGMLAFGEWRLDTTGRHLLDAEGTLVALSGAEYRLLRVFLDHPQ
HHHHHCCCCCCCHHHHCCEEEEEEEEECCCCCEEECCCCCEEEECCCCHHHHHHHHHCCH
RVLTRDQLLNLTQGRQSDPFDRSIDLLVSRLRQRLRDGAREPRYIKTLRNEGYVFSSAVT
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEHHHH
AIEGTS
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]