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The map label for this gene is pccB [H]

Identifier: 189353802

GI number: 189353802

Start: 2094299

End: 2095906

Strand: Reverse

Name: pccB [H]

Synonym: BMULJ_05049

Alternate gene names: 189353802

Gene position: 2095906-2094299 (Counterclockwise)

Preceding gene: 189353803

Following gene: 189353801

Centisome position: 84.75

GC content: 67.54

Gene sequence:

>1608_bases
ATGCCGATCATCGAATCCAAACTGAACCCGCGTTCGGAAGAATTCCGTGCGAATGCCGCGGCGCTCGAGGCGGTCGTCGC
CGATCTGCGCGCGAAGATCGAGCAGCTCGCGCAAGGCGGCGGCCAGGCCGCACGCGACAAGCATCTCGCGCGCGGCAAGC
TGCTGCCGCGCGACCGGATCGCGCAACTGCTCGATCCCGGTTCGCCGTTTCTCGAGCTGTCGCAACTCGCGGCGAACGGG
ATGTACAACGACGACGCGCCGGGCGCCGGCATCATCACCGGCATCGGGCGGATCGCCGGCCGCGAATGCGTGATCGTCTG
CAACGACGCGACGGTCAAGGGCGGCACGTACTATCCGATCACGGTGAAGAAGCACGTGCGCGCGCAGGAAATCGCCGCGG
AAAACCGGCTGCCGTGCGTGTATCTCGTCGATTCGGGCGGCGCGAACCTGCCGAACCAGGACGACGTCTTCCCCGATCGC
GACCACTTCGGCCGCATCTTCTTCAATCAGGCGACGATGTCGGCGGCCGGCATCGCGCAGATCGCGGTCGTGATGGGTTC
GTGCACGGCGGGCGGCGCCTACGTGCCGGCGATGAGCGACGAGTCGATCATCGTGAAGAACCAGGGCACGATTTTTCTCG
GCGGCCCGCCGCTCGTGAAGGCGGCGACCGGCGAGGAAGTGAGCGCCGAGGATCTCGGCGGCGGCGACGTGCACACGCGC
CTGTCGGGCGTTGCCGATCATCTCGCGCAGAACGACGCGCATGCGCTGTCGATCGCGCGCAGCATCGTCGGTCATCTGGC
GCCGAAGATGCCGTCGCCGGTCGCGGTACGCGAGCCGAAGCCGCCGCGCTACGACGCAGCGAGCCTCTACGGCGTGATTC
CCGTCGATACGCGCAAGCCGTTCGACGTGCGCGAGGTGATCGCGCGCATCGTCGACGATTCGGAGTTCGACGAATTCAAG
GCGCGCTACGGCACGACGCTCGTCACGGGCTTCGCGCATATCTGGGGCTATCCGGTCGGCATCGTCGCGAACAACGGCAT
CCTGTTTTCCGAGTCGGCGGTCAAGGGCGCGCACTTCATCGAGCTGTGCTGCCAGCGCAAGATTCCGCTCGTGTTCCTGC
AGAACATCACGGGCTTCATGGTCGGCCGCAAGTACGAGAACGAAGGCATCGCGCGGCACGGCGCGAAGATGGTGACGGCC
GTGTCGAACGCGAAGGTGCCGAAGTTCACGGTGATCATCGGCGGCTCGTTCGGCGCCGGCAACTACGGGATGTGCGGCCG
CGCGTTCGGGCCGCGCTTCCTGTGGATGTGGCCGAACGCGCGGATCTCGGTGATGGGCGGCGAGCAGGCCGCGTCGGTGC
TCGCGACCGTGCGCCGCGACGGGATCGAGGCGAAGGGCGGCACGTGGTCCGCGCAGGAGGAGGAGGCGTTCAAGCAGCCG
ATCCGCGATCAGTACGAGCGGCAGGGCCATCCGTACTACGCGAGCGCGCGGCTCTGGGACGACGGCGTGATCGATCCCGC
GCAGACGCGCGACGTGCTCGGCCTCGGGCTCGCCGCGTCGATGAACGCGCCGATCGACGAGACGCGCTTCGGCGTGTTCC
GCATGTGA

Upstream 100 bases:

>100_bases
GATCGGCGCCGGCACGAGCGAGATCCGCCGGATGCTGATCGGCCGCGAGCTGTTCGCGGAAACGATGTAACGCCCACGTC
ACGCGAACGGAGCTCCGTCG

Downstream 100 bases:

>100_bases
TGCCGGGGAGGACTGACCGATGCGATACGAAACGATCAAGGTAAGCGAAGCCGGCCGCGTCGCGACCGTCACGCTCGCGC
GCCCCGACGTGCGCAACGCG

Product: propionyl-CoA carboxylase beta chain

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 534

Protein sequence:

>535_residues
MPIIESKLNPRSEEFRANAAALEAVVADLRAKIEQLAQGGGQAARDKHLARGKLLPRDRIAQLLDPGSPFLELSQLAANG
MYNDDAPGAGIITGIGRIAGRECVIVCNDATVKGGTYYPITVKKHVRAQEIAAENRLPCVYLVDSGGANLPNQDDVFPDR
DHFGRIFFNQATMSAAGIAQIAVVMGSCTAGGAYVPAMSDESIIVKNQGTIFLGGPPLVKAATGEEVSAEDLGGGDVHTR
LSGVADHLAQNDAHALSIARSIVGHLAPKMPSPVAVREPKPPRYDAASLYGVIPVDTRKPFDVREVIARIVDDSEFDEFK
ARYGTTLVTGFAHIWGYPVGIVANNGILFSESAVKGAHFIELCCQRKIPLVFLQNITGFMVGRKYENEGIARHGAKMVTA
VSNAKVPKFTVIIGGSFGAGNYGMCGRAFGPRFLWMWPNARISVMGGEQAASVLATVRRDGIEAKGGTWSAQEEEAFKQP
IRDQYERQGHPYYASARLWDDGVIDPAQTRDVLGLGLAASMNAPIDETRFGVFRM

Sequences:

>Translated_535_residues
MPIIESKLNPRSEEFRANAAALEAVVADLRAKIEQLAQGGGQAARDKHLARGKLLPRDRIAQLLDPGSPFLELSQLAANG
MYNDDAPGAGIITGIGRIAGRECVIVCNDATVKGGTYYPITVKKHVRAQEIAAENRLPCVYLVDSGGANLPNQDDVFPDR
DHFGRIFFNQATMSAAGIAQIAVVMGSCTAGGAYVPAMSDESIIVKNQGTIFLGGPPLVKAATGEEVSAEDLGGGDVHTR
LSGVADHLAQNDAHALSIARSIVGHLAPKMPSPVAVREPKPPRYDAASLYGVIPVDTRKPFDVREVIARIVDDSEFDEFK
ARYGTTLVTGFAHIWGYPVGIVANNGILFSESAVKGAHFIELCCQRKIPLVFLQNITGFMVGRKYENEGIARHGAKMVTA
VSNAKVPKFTVIIGGSFGAGNYGMCGRAFGPRFLWMWPNARISVMGGEQAASVLATVRRDGIEAKGGTWSAQEEEAFKQP
IRDQYERQGHPYYASARLWDDGVIDPAQTRDVLGLGLAASMNAPIDETRFGVFRM
>Mature_534_residues
PIIESKLNPRSEEFRANAAALEAVVADLRAKIEQLAQGGGQAARDKHLARGKLLPRDRIAQLLDPGSPFLELSQLAANGM
YNDDAPGAGIITGIGRIAGRECVIVCNDATVKGGTYYPITVKKHVRAQEIAAENRLPCVYLVDSGGANLPNQDDVFPDRD
HFGRIFFNQATMSAAGIAQIAVVMGSCTAGGAYVPAMSDESIIVKNQGTIFLGGPPLVKAATGEEVSAEDLGGGDVHTRL
SGVADHLAQNDAHALSIARSIVGHLAPKMPSPVAVREPKPPRYDAASLYGVIPVDTRKPFDVREVIARIVDDSEFDEFKA
RYGTTLVTGFAHIWGYPVGIVANNGILFSESAVKGAHFIELCCQRKIPLVFLQNITGFMVGRKYENEGIARHGAKMVTAV
SNAKVPKFTVIIGGSFGAGNYGMCGRAFGPRFLWMWPNARISVMGGEQAASVLATVRRDGIEAKGGTWSAQEEEAFKQPI
RDQYERQGHPYYASARLWDDGVIDPAQTRDVLGLGLAASMNAPIDETRFGVFRM

Specific function: Unknown

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI11545863, Length=525, Percent_Identity=65.5238095238095, Blast_Score=708, Evalue=0.0,
Organism=Homo sapiens, GI119943100, Length=524, Percent_Identity=32.4427480916031, Blast_Score=248, Evalue=1e-65,
Organism=Homo sapiens, GI295821216, Length=544, Percent_Identity=31.6176470588235, Blast_Score=235, Evalue=7e-62,
Organism=Homo sapiens, GI310133460, Length=132, Percent_Identity=59.0909090909091, Blast_Score=150, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17552936, Length=533, Percent_Identity=62.6641651031895, Blast_Score=712, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25147359, Length=528, Percent_Identity=33.5227272727273, Blast_Score=252, Evalue=4e-67,
Organism=Caenorhabditis elegans, GI25147362, Length=494, Percent_Identity=34.6153846153846, Blast_Score=251, Evalue=6e-67,
Organism=Drosophila melanogaster, GI24586065, Length=553, Percent_Identity=63.2911392405063, Blast_Score=717, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: NA

Molecular weight: Translated: 57448; Mature: 57317

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIIESKLNPRSEEFRANAAALEAVVADLRAKIEQLAQGGGQAARDKHLARGKLLPRDRI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHH
AQLLDPGSPFLELSQLAANGMYNDDAPGAGIITGIGRIAGRECVIVCNDATVKGGTYYPI
HHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCEECCCEEEEE
TVKKHVRAQEIAAENRLPCVYLVDSGGANLPNQDDVFPDRDHFGRIFFNQATMSAAGIAQ
EHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCHHCCEEEEECHHHHHHHHHH
IAVVMGSCTAGGAYVPAMSDESIIVKNQGTIFLGGPPLVKAATGEEVSAEDLGGGDVHTR
HHHHHHCCCCCCEEECCCCCCEEEEECCCEEEECCCCEEEECCCCCCCHHHCCCCHHHHH
LSGVADHLAQNDAHALSIARSIVGHLAPKMPSPVAVREPKPPRYDAASLYGVIPVDTRKP
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCEEEEEECCCCCC
FDVREVIARIVDDSEFDEFKARYGTTLVTGFAHIWGYPVGIVANNGILFSESAVKGAHFI
CCHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHCCCEEEEECCCEEEECCHHCHHHHH
ELCCQRKIPLVFLQNITGFMVGRKYENEGIARHGAKMVTAVSNAKVPKFTVIIGGSFGAG
HHHHCCCCCEEEECCCHHHHHCCEECCCCHHHHCCHHEEECCCCCCCEEEEEEECCCCCC
NYGMCGRAFGPRFLWMWPNARISVMGGEQAASVLATVRRDGIEAKGGTWSAQEEEAFKQP
CCCCCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
IRDQYERQGHPYYASARLWDDGVIDPAQTRDVLGLGLAASMNAPIDETRFGVFRM
HHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHCCCHHCCCCCCCCCCCCEECC
>Mature Secondary Structure 
PIIESKLNPRSEEFRANAAALEAVVADLRAKIEQLAQGGGQAARDKHLARGKLLPRDRI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHH
AQLLDPGSPFLELSQLAANGMYNDDAPGAGIITGIGRIAGRECVIVCNDATVKGGTYYPI
HHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCEECCCEEEEE
TVKKHVRAQEIAAENRLPCVYLVDSGGANLPNQDDVFPDRDHFGRIFFNQATMSAAGIAQ
EHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCHHCCEEEEECHHHHHHHHHH
IAVVMGSCTAGGAYVPAMSDESIIVKNQGTIFLGGPPLVKAATGEEVSAEDLGGGDVHTR
HHHHHHCCCCCCEEECCCCCCEEEEECCCEEEECCCCEEEECCCCCCCHHHCCCCHHHHH
LSGVADHLAQNDAHALSIARSIVGHLAPKMPSPVAVREPKPPRYDAASLYGVIPVDTRKP
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCEEEEEECCCCCC
FDVREVIARIVDDSEFDEFKARYGTTLVTGFAHIWGYPVGIVANNGILFSESAVKGAHFI
CCHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHCCCEEEEECCCEEEECCHHCHHHHH
ELCCQRKIPLVFLQNITGFMVGRKYENEGIARHGAKMVTAVSNAKVPKFTVIIGGSFGAG
HHHHCCCCCEEEECCCHHHHHCCEECCCCHHHHCCHHEEECCCCCCCEEEEEEECCCCCC
NYGMCGRAFGPRFLWMWPNARISVMGGEQAASVLATVRRDGIEAKGGTWSAQEEEAFKQP
CCCCCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
IRDQYERQGHPYYASARLWDDGVIDPAQTRDVLGLGLAASMNAPIDETRFGVFRM
HHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHCCCHHCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9387222 [H]