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The map label for this gene is paaG [C]

Identifier: 189353801

GI number: 189353801

Start: 2093494

End: 2094279

Strand: Reverse

Name: paaG [C]

Synonym: BMULJ_05048

Alternate gene names: 189353801

Gene position: 2094279-2093494 (Counterclockwise)

Preceding gene: 189353802

Following gene: 189353800

Centisome position: 84.68

GC content: 72.01

Gene sequence:

>786_bases
ATGCGATACGAAACGATCAAGGTAAGCGAAGCCGGCCGCGTCGCGACCGTCACGCTCGCGCGCCCCGACGTGCGCAACGC
GTTCAACGAGACGGCGATCGCCGAGCTGACCACCGCGTTCGAATGGCTCGACGCGCACGAGGGCGTGCGCGCGGTCGTGC
TCGCGGCCGAAGGCCCGGCGTTCTGCGCGGGCGCCGACCTGAACTGGATGAAGAAGATGGCCGGCTACTCGGACGACGAG
AACCGCGCCGATGCGCGCAAGCTCGCGCGGATGCTCGAGGCGATCCACCGCTGCGGCAAGCCCGTGATCGCGCGCGTGCA
TGGCGATGCGTACGCCGGAGGCGTCGGTCTCGTGGCCGCGGCCGACATCGCGATCGCGGCCGACACCGCGAAGTTCTGCC
TGTCCGAAGCGCGGCTCGGGCTGATTCCGGCGACGATCGCGCCGTACGTCGTGCGCGCGATGGGCGAGCGCGCGGCGCGC
CGCTACTTCACGACCGCCGAGGTGTTCGACAGCGCGCGTGCGGCGTCGCTCGGCTTCATCCACGATGCGGTGCCGGCCGC
GGCGCTCGACGAGACCGTCGCGAAGCTGGCCGCGACGCTGGTCGCGAACGGCCCGGACGCCGTGCGCGCCTGCAAGCGGC
TCGTCGCCGACGTCGCGGGCCGTCCGCTCGATGCGGCGCTGATCGAGCAGACCGCCGACTGGATCGCGCGTACCCGCGCG
GGCGCGGAAGCGCGCGAAGGGATCGCGTCCTTCCTGGAGAAACGCACGCCGTCCTGGCGTGACTGA

Upstream 100 bases:

>100_bases
CGCGACGTGCTCGGCCTCGGGCTCGCCGCGTCGATGAACGCGCCGATCGACGAGACGCGCTTCGGCGTGTTCCGCATGTG
ATGCCGGGGAGGACTGACCG

Downstream 100 bases:

>100_bases
ACGCGCGGCGGCCGGCGCCGCCCGTGTCGCGTGACCCCAACCTTTTCCGGACGACAGCCATGTTCGACAAGATTCTGATC
GCCAACCGCGGCGAAATCGC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MRYETIKVSEAGRVATVTLARPDVRNAFNETAIAELTTAFEWLDAHEGVRAVVLAAEGPAFCAGADLNWMKKMAGYSDDE
NRADARKLARMLEAIHRCGKPVIARVHGDAYAGGVGLVAAADIAIAADTAKFCLSEARLGLIPATIAPYVVRAMGERAAR
RYFTTAEVFDSARAASLGFIHDAVPAAALDETVAKLAATLVANGPDAVRACKRLVADVAGRPLDAALIEQTADWIARTRA
GAEAREGIASFLEKRTPSWRD

Sequences:

>Translated_261_residues
MRYETIKVSEAGRVATVTLARPDVRNAFNETAIAELTTAFEWLDAHEGVRAVVLAAEGPAFCAGADLNWMKKMAGYSDDE
NRADARKLARMLEAIHRCGKPVIARVHGDAYAGGVGLVAAADIAIAADTAKFCLSEARLGLIPATIAPYVVRAMGERAAR
RYFTTAEVFDSARAASLGFIHDAVPAAALDETVAKLAATLVANGPDAVRACKRLVADVAGRPLDAALIEQTADWIARTRA
GAEAREGIASFLEKRTPSWRD
>Mature_261_residues
MRYETIKVSEAGRVATVTLARPDVRNAFNETAIAELTTAFEWLDAHEGVRAVVLAAEGPAFCAGADLNWMKKMAGYSDDE
NRADARKLARMLEAIHRCGKPVIARVHGDAYAGGVGLVAAADIAIAADTAKFCLSEARLGLIPATIAPYVVRAMGERAAR
RYFTTAEVFDSARAASLGFIHDAVPAAALDETVAKLAATLVANGPDAVRACKRLVADVAGRPLDAALIEQTADWIARTRA
GAEAREGIASFLEKRTPSWRD

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI31542718, Length=246, Percent_Identity=26.4227642276423, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI194097323, Length=265, Percent_Identity=27.5471698113208, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI70995211, Length=148, Percent_Identity=36.4864864864865, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI4502327, Length=247, Percent_Identity=30.7692307692308, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1788597, Length=262, Percent_Identity=29.7709923664122, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787659, Length=256, Percent_Identity=30.078125, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1787660, Length=248, Percent_Identity=29.0322580645161, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87082183, Length=267, Percent_Identity=23.9700374531835, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI221142681, Length=269, Percent_Identity=26.0223048327138, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1788682, Length=246, Percent_Identity=26.4227642276423, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25145438, Length=250, Percent_Identity=28, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17554946, Length=256, Percent_Identity=29.6875, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17540714, Length=201, Percent_Identity=29.8507462686567, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17540306, Length=186, Percent_Identity=31.1827956989247, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17535521, Length=256, Percent_Identity=26.5625, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17534483, Length=151, Percent_Identity=26.4900662251656, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560910, Length=256, Percent_Identity=27.34375, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17536985, Length=139, Percent_Identity=30.9352517985612, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17549921, Length=201, Percent_Identity=26.865671641791, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24653139, Length=256, Percent_Identity=32.03125, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI20129971, Length=264, Percent_Identity=30.3030303030303, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24653477, Length=264, Percent_Identity=30.3030303030303, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI19922422, Length=261, Percent_Identity=26.0536398467433, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19920382, Length=225, Percent_Identity=31.5555555555556, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24654903, Length=220, Percent_Identity=24.5454545454545, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 27780; Mature: 27780

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYETIKVSEAGRVATVTLARPDVRNAFNETAIAELTTAFEWLDAHEGVRAVVLAAEGPA
CCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
FCAGADLNWMKKMAGYSDDENRADARKLARMLEAIHRCGKPVIARVHGDAYAGGVGLVAA
EEECCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHCCCHHHHHH
ADIAIAADTAKFCLSEARLGLIPATIAPYVVRAMGERAARRYFTTAEVFDSARAASLGFI
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDAVPAAALDETVAKLAATLVANGPDAVRACKRLVADVAGRPLDAALIEQTADWIARTRA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
GAEAREGIASFLEKRTPSWRD
CHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRYETIKVSEAGRVATVTLARPDVRNAFNETAIAELTTAFEWLDAHEGVRAVVLAAEGPA
CCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
FCAGADLNWMKKMAGYSDDENRADARKLARMLEAIHRCGKPVIARVHGDAYAGGVGLVAA
EEECCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHCCCHHHHHH
ADIAIAADTAKFCLSEARLGLIPATIAPYVVRAMGERAARRYFTTAEVFDSARAASLGFI
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDAVPAAALDETVAKLAATLVANGPDAVRACKRLVADVAGRPLDAALIEQTADWIARTRA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
GAEAREGIASFLEKRTPSWRD
CHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA