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The map label for this gene is ttuB [H]

Identifier: 189353773

GI number: 189353773

Start: 2054514

End: 2055839

Strand: Direct

Name: ttuB [H]

Synonym: BMULJ_05020

Alternate gene names: 189353773

Gene position: 2054514-2055839 (Clockwise)

Preceding gene: 189353772

Following gene: 189353774

Centisome position: 83.07

GC content: 65.31

Gene sequence:

>1326_bases
ATGACTGCACTCGACGCGGCTGCGCGCCGCTCGCCCGCCGCGGCTGCCAGCCCGGCCGAACTCGACCTGACCTACAAGAA
AGTGTTCTGGCGCATCGTGCCGTTCCTGATGCTCTGCTACGTGGTCGCGTATCTCGACCGCGTCAACGTCGGCTTCGCGA
AGCTGCAGATGTCGCAGGACCTCGCCTTCAGCGAGACGGTATTCGGCCTCGGCGCCGGCATCTTCTTCCTCGGCTACTTC
CTGTTCGAGCTGCCGAGCAACATGCTGATGCACCGGATCGGCGCGCGCATCTGGATCGCGCGGATCATGATCACGTGGGG
GCTGCTGTCCGCCATGTTCGCGTTCGTGAAGACGCCCACGCAGTTCTACGTGCTGCGCTTCCTGCTCGGTCTCGCCGAAG
CGGGCTTCTATCCGGGCGTGATCCTCTATCTGACGTACTGGTTCCCGTCGCACCGCCGCGCGAAGATCATCGCGGTGTTC
ATGTCGGCGATTCCGGTGTCGGGCATCTTCGGCAACCCGCTGTCGGGCTGGATCATGGAGGCGTTCCACGGCGGCTCGGG
CTTCCACGGCTGGCAGTGGATGTTCATGATCGAAGCCGTGCCGGCCGTGCTGGTCGGCATCGCGACGATCCTCTATCTCG
ACAACAACATTCGCAGCGCGAAGTGGCTGAACGAGCGCGAAAAGCAGCTCCTCGAAGACGAGATCGCCGCGCAGCCGCAG
GAACAGCAGAAGCACGGCCATTCGCTGAAGGCCGTGTTCGCCGACCCGCGCATGTGGTGGATGTCGCTGATCTACTTCGC
GTTCGTCACCGGCCAGTACGGGCTCACGTTCTGGATGCCGACGCTCGTCAAGTCCACCGGCATCACCGACACGCTGCAGG
TCGGCCTGCTGTCCGCGATTCCGTTCGTCGTCGCGATCGTCGTGATGAACCTGTTCGGCCACAGCGCGGACAAGCGCCGC
GAGCGCCGCTGGCACCTGATCGTGCCGGCGCTGATGGGCGCCGTCGGCTTTGCGGTCGCCGCGTCGTACTCGCACAATAC
GGCGGTGTCGATCGTGTTCCTGTCGATCGCGGCAGGCGGCGTGCTGACCTGTGCACCGCTGTTCTGGTCGCTGCCGACCG
CGTTCCTCGCGGGCAGCGCGGCCGCCGCCGGCATCGCGATCATCAACTCGGTCGGCAACCTCGCCGGCTTCGCGAGCCCG
TACGTGATCGGCTATCTGAAGGACCTCACGCACAGCACGTCGTCGGGCATGTACGTGCTCGCCGCGATGCTCGTGATCGG
CGCGTTCGCCGTGTGGCTCACGCCCGCGAAACTCGTGAACCGCTGA

Upstream 100 bases:

>100_bases
GCGAATCTCATGCCCGCCGTGTGCGCGGGCCCTTCCGTCAGCACACACCTACGACCGGCAGCGTGCGCGCCGCCGGCACT
CGCCACCTTTGGAGACGACG

Downstream 100 bases:

>100_bases
TCGGCCACCGTTCGATGCGGGGCATCGCGCCCCGCCCCATTCATTCACAGGATCCGCTGCCATGCCACGCTTCGCCGCCA
ACCTCTCGATGATGTACAAC

Product: permease of the major facilitator superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MTALDAAARRSPAAAASPAELDLTYKKVFWRIVPFLMLCYVVAYLDRVNVGFAKLQMSQDLAFSETVFGLGAGIFFLGYF
LFELPSNMLMHRIGARIWIARIMITWGLLSAMFAFVKTPTQFYVLRFLLGLAEAGFYPGVILYLTYWFPSHRRAKIIAVF
MSAIPVSGIFGNPLSGWIMEAFHGGSGFHGWQWMFMIEAVPAVLVGIATILYLDNNIRSAKWLNEREKQLLEDEIAAQPQ
EQQKHGHSLKAVFADPRMWWMSLIYFAFVTGQYGLTFWMPTLVKSTGITDTLQVGLLSAIPFVVAIVVMNLFGHSADKRR
ERRWHLIVPALMGAVGFAVAASYSHNTAVSIVFLSIAAGGVLTCAPLFWSLPTAFLAGSAAAAGIAIINSVGNLAGFASP
YVIGYLKDLTHSTSSGMYVLAAMLVIGAFAVWLTPAKLVNR

Sequences:

>Translated_441_residues
MTALDAAARRSPAAAASPAELDLTYKKVFWRIVPFLMLCYVVAYLDRVNVGFAKLQMSQDLAFSETVFGLGAGIFFLGYF
LFELPSNMLMHRIGARIWIARIMITWGLLSAMFAFVKTPTQFYVLRFLLGLAEAGFYPGVILYLTYWFPSHRRAKIIAVF
MSAIPVSGIFGNPLSGWIMEAFHGGSGFHGWQWMFMIEAVPAVLVGIATILYLDNNIRSAKWLNEREKQLLEDEIAAQPQ
EQQKHGHSLKAVFADPRMWWMSLIYFAFVTGQYGLTFWMPTLVKSTGITDTLQVGLLSAIPFVVAIVVMNLFGHSADKRR
ERRWHLIVPALMGAVGFAVAASYSHNTAVSIVFLSIAAGGVLTCAPLFWSLPTAFLAGSAAAAGIAIINSVGNLAGFASP
YVIGYLKDLTHSTSSGMYVLAAMLVIGAFAVWLTPAKLVNR
>Mature_440_residues
TALDAAARRSPAAAASPAELDLTYKKVFWRIVPFLMLCYVVAYLDRVNVGFAKLQMSQDLAFSETVFGLGAGIFFLGYFL
FELPSNMLMHRIGARIWIARIMITWGLLSAMFAFVKTPTQFYVLRFLLGLAEAGFYPGVILYLTYWFPSHRRAKIIAVFM
SAIPVSGIFGNPLSGWIMEAFHGGSGFHGWQWMFMIEAVPAVLVGIATILYLDNNIRSAKWLNEREKQLLEDEIAAQPQE
QQKHGHSLKAVFADPRMWWMSLIYFAFVTGQYGLTFWMPTLVKSTGITDTLQVGLLSAIPFVVAIVVMNLFGHSADKRRE
RRWHLIVPALMGAVGFAVAASYSHNTAVSIVFLSIAAGGVLTCAPLFWSLPTAFLAGSAAAAGIAIINSVGNLAGFASPY
VIGYLKDLTHSTSSGMYVLAAMLVIGAFAVWLTPAKLVNR

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=380, Percent_Identity=22.8947368421053, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI9945322, Length=463, Percent_Identity=24.1900647948164, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI21322234, Length=464, Percent_Identity=22.4137931034483, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87082071, Length=417, Percent_Identity=37.8896882494005, Blast_Score=275, Evalue=4e-75,
Organism=Escherichia coli, GI2367379, Length=404, Percent_Identity=22.7722772277228, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789515, Length=421, Percent_Identity=23.0403800475059, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87082320, Length=409, Percent_Identity=23.2273838630807, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1789152, Length=425, Percent_Identity=23.7647058823529, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560030, Length=344, Percent_Identity=25.8720930232558, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321698, Length=320, Percent_Identity=24.0625, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322025, Length=178, Percent_Identity=30.3370786516854, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323032, Length=306, Percent_Identity=24.5098039215686, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319876, Length=245, Percent_Identity=22.0408163265306, Blast_Score=73, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6322612, Length=332, Percent_Identity=23.4939759036145, Blast_Score=73, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6321502, Length=403, Percent_Identity=23.5732009925558, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319250, Length=330, Percent_Identity=20.9090909090909, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324410, Length=161, Percent_Identity=26.7080745341615, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24584153, Length=362, Percent_Identity=23.2044198895028, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24583789, Length=371, Percent_Identity=25.6064690026954, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20130167, Length=439, Percent_Identity=23.0068337129841, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639764, Length=372, Percent_Identity=22.3118279569892, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24654215, Length=393, Percent_Identity=24.1730279898219, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI19922400, Length=388, Percent_Identity=24.2268041237113, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48512; Mature: 48381

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCHHHHHCC
>Mature Secondary Structure 
TALDAAARRSPAAAASPAELDLTYKKVFWRIVPFLMLCYVVAYLDRVNVGFAKLQMSQD
CCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHC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HHHHHHHHHHHHHCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]