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The map label for this gene is gip [C]

Identifier: 189353774

GI number: 189353774

Start: 2055901

End: 2056677

Strand: Direct

Name: gip [C]

Synonym: BMULJ_05021

Alternate gene names: 189353774

Gene position: 2055901-2056677 (Clockwise)

Preceding gene: 189353773

Following gene: 189353775

Centisome position: 83.13

GC content: 67.82

Gene sequence:

>777_bases
ATGCCACGCTTCGCCGCCAACCTCTCGATGATGTACAACGAGCATGCGTTCCTCGAACGCTTCGCCGCCGCCGCGTACGA
CGGCTTCAAGGCCGTCGAGTACCTGTTCCCGTACGACTTTGCGGCCGAGGACATCCGCGCGCGCCTCGACGCGCACGGCC
TCGAACAGGCGCTGTTCAACGCGCCGCCCGGCGACTGGGCGGCCGGCGAGCGCGGCATCGCATCGCTGCCGGGCCGCGAG
GACGAGTTCCGGCGCAGCATCGACCGTGCGCTCGACTACGCGCGCGTGCTCGGCAACAAGAAGCTGCACGTGATGGCCGG
CCTCGTCGCGCCCGGCGCCGATCGGGCGCGCCATCGCGACACGTACGTCGCCAATCTGCGGCACGCGGCGCAGGCGGCGG
CCGCGCACGGCATCACGGTGCTGATCGAGCCGATCAACCAGCGCGACATGCCCGGCTATTTCCTGAGTCGCCAGGACGAT
GCGCACGCGATCTGCGCGGAAGTCGGCGCGCCGAACCTGAAGGTGCAGTTCGACTGCTACCACTGCCAGATCGTCGAAGG
CGATCTCGCGATGAAGCTCAAGCGCGACTTCGCGGGCATCGGCCACATCCAGATCGCCGGCGTGCCCGAACGGCACGAAC
CCGATCTCGGCGAACTGAACTATCCGTATCTGTTCGAGCTGATCGACGCGCTCGGCTACGACGGCTGGATCGGCTGCGAA
TATCGGCCGAAGGCCGGCACGTCGGCCGGCCTCGGCTGGCTCAAACCGTACCTGTAA

Upstream 100 bases:

>100_bases
GCCGTGTGGCTCACGCCCGCGAAACTCGTGAACCGCTGATCGGCCACCGTTCGATGCGGGGCATCGCGCCCCGCCCCATT
CATTCACAGGATCCGCTGCC

Downstream 100 bases:

>100_bases
TTCGCGTATCTCACGTATTCCTGCGAGGGCAACCAACATGAAAGTACTGATCACCGGCGGCGCCGGCTTTCTCGGCCAGC
GGCTCGCGCGCAAGCTGCTC

Product: hydroxypyruvate isomerase

Products: 2-hydroxy-3-oxopropanoate

Alternate protein names: ORF4 [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MPRFAANLSMMYNEHAFLERFAAAAYDGFKAVEYLFPYDFAAEDIRARLDAHGLEQALFNAPPGDWAAGERGIASLPGRE
DEFRRSIDRALDYARVLGNKKLHVMAGLVAPGADRARHRDTYVANLRHAAQAAAAHGITVLIEPINQRDMPGYFLSRQDD
AHAICAEVGAPNLKVQFDCYHCQIVEGDLAMKLKRDFAGIGHIQIAGVPERHEPDLGELNYPYLFELIDALGYDGWIGCE
YRPKAGTSAGLGWLKPYL

Sequences:

>Translated_258_residues
MPRFAANLSMMYNEHAFLERFAAAAYDGFKAVEYLFPYDFAAEDIRARLDAHGLEQALFNAPPGDWAAGERGIASLPGRE
DEFRRSIDRALDYARVLGNKKLHVMAGLVAPGADRARHRDTYVANLRHAAQAAAAHGITVLIEPINQRDMPGYFLSRQDD
AHAICAEVGAPNLKVQFDCYHCQIVEGDLAMKLKRDFAGIGHIQIAGVPERHEPDLGELNYPYLFELIDALGYDGWIGCE
YRPKAGTSAGLGWLKPYL
>Mature_257_residues
PRFAANLSMMYNEHAFLERFAAAAYDGFKAVEYLFPYDFAAEDIRARLDAHGLEQALFNAPPGDWAAGERGIASLPGRED
EFRRSIDRALDYARVLGNKKLHVMAGLVAPGADRARHRDTYVANLRHAAQAAAAHGITVLIEPINQRDMPGYFLSRQDDA
HAICAEVGAPNLKVQFDCYHCQIVEGDLAMKLKRDFAGIGHIQIAGVPERHEPDLGELNYPYLFELIDALGYDGWIGCEY
RPKAGTSAGLGWLKPYL

Specific function: Unknown

COG id: COG3622

COG function: function code G; Hydroxypyruvate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hyi family [H]

Homologues:

Organism=Homo sapiens, GI300068962, Length=262, Percent_Identity=43.5114503816794, Blast_Score=211, Evalue=6e-55,
Organism=Homo sapiens, GI300068964, Length=243, Percent_Identity=42.798353909465, Blast_Score=186, Evalue=1e-47,
Organism=Escherichia coli, GI1789095, Length=258, Percent_Identity=50.7751937984496, Blast_Score=258, Evalue=2e-70,
Organism=Escherichia coli, GI1786718, Length=257, Percent_Identity=48.2490272373541, Blast_Score=257, Evalue=5e-70,
Organism=Caenorhabditis elegans, GI17552022, Length=240, Percent_Identity=40.4166666666667, Blast_Score=184, Evalue=3e-47,
Organism=Drosophila melanogaster, GI17530883, Length=256, Percent_Identity=39.84375, Blast_Score=183, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: 5.3.1.22

Molecular weight: Translated: 28636; Mature: 28505

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRFAANLSMMYNEHAFLERFAAAAYDGFKAVEYLFPYDFAAEDIRARLDAHGLEQALFN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
APPGDWAAGERGIASLPGREDEFRRSIDRALDYARVLGNKKLHVMAGLVAPGADRARHRD
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHH
TYVANLRHAAQAAAAHGITVLIEPINQRDMPGYFLSRQDDAHAICAEVGAPNLKVQFDCY
HHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEECCCCCHHHHHHHCCCCCEEEEEEEE
HCQIVEGDLAMKLKRDFAGIGHIQIAGVPERHEPDLGELNYPYLFELIDALGYDGWIGCE
EEEEECCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCE
YRPKAGTSAGLGWLKPYL
ECCCCCCCCCCCHHCCCC
>Mature Secondary Structure 
PRFAANLSMMYNEHAFLERFAAAAYDGFKAVEYLFPYDFAAEDIRARLDAHGLEQALFN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
APPGDWAAGERGIASLPGREDEFRRSIDRALDYARVLGNKKLHVMAGLVAPGADRARHRD
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHH
TYVANLRHAAQAAAAHGITVLIEPINQRDMPGYFLSRQDDAHAICAEVGAPNLKVQFDCY
HHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEECCCCCHHHHHHHCCCCCEEEEEEEE
HCQIVEGDLAMKLKRDFAGIGHIQIAGVPERHEPDLGELNYPYLFELIDALGYDGWIGCE
EEEEECCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCE
YRPKAGTSAGLGWLKPYL
ECCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxypyruvate

Specific reaction: hydroxypyruvate = 2-hydroxy-3-oxopropanoate; Other Name(s): hydroxypyruvate ketol-isomerase

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7851418 [H]