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The map label for this gene is aspB [H]

Identifier: 189353729

GI number: 189353729

Start: 1998452

End: 1999873

Strand: Direct

Name: aspB [H]

Synonym: BMULJ_04974

Alternate gene names: 189353729

Gene position: 1998452-1999873 (Clockwise)

Preceding gene: 189353727

Following gene: 189353730

Centisome position: 80.81

GC content: 69.06

Gene sequence:

>1422_bases
ATGAAACGATATGCGGCGCTGGCGCAGACGATTGCCGATTCGATTCGGCGAGGCGATCTGGCACCCGGCGAGCGCATTCC
GACCGTGCGCGCCGCGTGCCGCGCGTATCGCGTGAGCCCGTCGACGGTGTTTCGCGCTTACTACCAGCTCGAGAGCGAGG
GTCTGATCGTGGCGCGCCCGCGCTCGGGCTATTTCGTCGCGAATCTCGACGCGTCGCGGCTGCGCTCGACGCTCGATCCG
CTGCGCAAGCCGGCCGCCGCGCCGCACGTCGCCGAGACCGCGCTGTGTCGTCTGCTCGACTCGCTGAAACACGGCGACGT
CGTCCCGCTCGGTTCCGCGTTCGCGAACTATTCGCTGTTTCCGATGAGCAGCCTGTGGCGCTACGTGCAGTCCGCGACGC
GCAACATGGACCGCGTGACGATGCTGTCCGGTCTGCCGCCCGGCGAAGACGGGCTGCGTCGCCAGATCGCGCTGCGCTAT
CTGACGGCCGGCGCGGCGCTGCCGATGGACGAGATCATCGTGACGACCGGCGCGCTCGACGCGCTGATGCTGAGCCTGCA
GGCGCTCACGCGTCCCGGCGAAGTGGTCGCGATCGAGCGGCCGGCGTTTCCCGCGGCGCTGCAGGCCGTGCAGCGGCTGC
ATCTGAAGGCGGTCGAAATTCCGGTCGATCCGCATACGGGCCTCGACCTCGATGCGCTGGCCGAGGCGCTCGACACGCAC
CCGGTGCGCGCGTGCTGGTTCATGACGTCGCTGCACAATCCGACCGGCGCGACGCTGTCCGACGAACGCAAGCGCGCCCT
GATCGAGCTGCTCGCGGCGCACCGCGTGCCGCTGATCGAAGACGACGTATACGGCGAACTGCAGTTCGGCCCCGCGCCCG
TGCGGCCCGCGAAGGTGTACGACGACAGCGGCCTCGTGCTGCATTGCGGATCGTTTTCGAAATGCCTCGCGCCCGGCTTC
CGGATCGGCTGGGTCGCGGCCGGCCGCTATGCGCGGCAGATCCGCCAGGCGAACTGCATGGGCACGCCGTCGGCCGACGT
GCCCGCGCAGCTCGCGATCTCCAGCTATCTTGGGCACGGCGGCTACGACCGCTTCCTGCGCAAGCTGCGGCGCAATCTCG
CCGCGCATCAGGCGCAAATGGTCGCCGCCGTGCACGCGTATTTTCCGCAGGGAACCGAAGTGTTCGCGCCCGGCGGCGGC
TATTTCCTGTGGATCGAATTGCCGAAGCGCGTCGACGCATTGCGCCTGTTCGGCGCCGCGCTCGAAAACGGCATCAGCAT
CGCGCCGGGCCCCATCTTCTCCGCAACCGGCGGCTTCCGTCGCTACGTGCGCCTCAACTACGGCCGGCCGTGGACGCCGG
CCGTCGAGAACGCGATGCAGACGATCGGCACGCTCGCCGCGCGACAACGACACCCGGAGTAG

Upstream 100 bases:

>100_bases
ATCAGAGCCCGTTAAAAACGTGCGGATCAGCGCGCGGCATGCGGTTGCGCGGCATGGCGCGCGTGCTACTCTTTTTTCAG
CAATGCACCGGAGTGAGGGC

Downstream 100 bases:

>100_bases
CTCCACCATGCGAATCCTGCCGAACCGGACCCTTCATGCACGCGACACGCTGCGCGGCGTCACGCACGCACGCGCGGCCG
GACGACGCAACGTCGTCTGC

Product: aspartate aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MKRYAALAQTIADSIRRGDLAPGERIPTVRAACRAYRVSPSTVFRAYYQLESEGLIVARPRSGYFVANLDASRLRSTLDP
LRKPAAAPHVAETALCRLLDSLKHGDVVPLGSAFANYSLFPMSSLWRYVQSATRNMDRVTMLSGLPPGEDGLRRQIALRY
LTAGAALPMDEIIVTTGALDALMLSLQALTRPGEVVAIERPAFPAALQAVQRLHLKAVEIPVDPHTGLDLDALAEALDTH
PVRACWFMTSLHNPTGATLSDERKRALIELLAAHRVPLIEDDVYGELQFGPAPVRPAKVYDDSGLVLHCGSFSKCLAPGF
RIGWVAAGRYARQIRQANCMGTPSADVPAQLAISSYLGHGGYDRFLRKLRRNLAAHQAQMVAAVHAYFPQGTEVFAPGGG
YFLWIELPKRVDALRLFGAALENGISIAPGPIFSATGGFRRYVRLNYGRPWTPAVENAMQTIGTLAARQRHPE

Sequences:

>Translated_473_residues
MKRYAALAQTIADSIRRGDLAPGERIPTVRAACRAYRVSPSTVFRAYYQLESEGLIVARPRSGYFVANLDASRLRSTLDP
LRKPAAAPHVAETALCRLLDSLKHGDVVPLGSAFANYSLFPMSSLWRYVQSATRNMDRVTMLSGLPPGEDGLRRQIALRY
LTAGAALPMDEIIVTTGALDALMLSLQALTRPGEVVAIERPAFPAALQAVQRLHLKAVEIPVDPHTGLDLDALAEALDTH
PVRACWFMTSLHNPTGATLSDERKRALIELLAAHRVPLIEDDVYGELQFGPAPVRPAKVYDDSGLVLHCGSFSKCLAPGF
RIGWVAAGRYARQIRQANCMGTPSADVPAQLAISSYLGHGGYDRFLRKLRRNLAAHQAQMVAAVHAYFPQGTEVFAPGGG
YFLWIELPKRVDALRLFGAALENGISIAPGPIFSATGGFRRYVRLNYGRPWTPAVENAMQTIGTLAARQRHPE
>Mature_473_residues
MKRYAALAQTIADSIRRGDLAPGERIPTVRAACRAYRVSPSTVFRAYYQLESEGLIVARPRSGYFVANLDASRLRSTLDP
LRKPAAAPHVAETALCRLLDSLKHGDVVPLGSAFANYSLFPMSSLWRYVQSATRNMDRVTMLSGLPPGEDGLRRQIALRY
LTAGAALPMDEIIVTTGALDALMLSLQALTRPGEVVAIERPAFPAALQAVQRLHLKAVEIPVDPHTGLDLDALAEALDTH
PVRACWFMTSLHNPTGATLSDERKRALIELLAAHRVPLIEDDVYGELQFGPAPVRPAKVYDDSGLVLHCGSFSKCLAPGF
RIGWVAAGRYARQIRQANCMGTPSADVPAQLAISSYLGHGGYDRFLRKLRRNLAAHQAQMVAAVHAYFPQGTEVFAPGGG
YFLWIELPKRVDALRLFGAALENGISIAPGPIFSATGGFRRYVRLNYGRPWTPAVENAMQTIGTLAARQRHPE

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=280, Percent_Identity=26.7857142857143, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI33469970, Length=280, Percent_Identity=26.7857142857143, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI4507369, Length=176, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1787710, Length=465, Percent_Identity=43.2258064516129, Blast_Score=371, Evalue=1e-104,
Organism=Escherichia coli, GI1790797, Length=472, Percent_Identity=35.1694915254237, Blast_Score=288, Evalue=6e-79,
Organism=Caenorhabditis elegans, GI17567663, Length=316, Percent_Identity=23.1012658227848, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321000, Length=270, Percent_Identity=24.8148148148148, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321236, Length=318, Percent_Identity=21.6981132075472, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21356535, Length=316, Percent_Identity=26.2658227848101, Blast_Score=99, Evalue=7e-21,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 51610; Mature: 51610

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRYAALAQTIADSIRRGDLAPGERIPTVRAACRAYRVSPSTVFRAYYQLESEGLIVARP
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEECC
RSGYFVANLDASRLRSTLDPLRKPAAAPHVAETALCRLLDSLKHGDVVPLGSAFANYSLF
CCCEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCC
PMSSLWRYVQSATRNMDRVTMLSGLPPGEDGLRRQIALRYLTAGAALPMDEIIVTTGALD
CHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ALMLSLQALTRPGEVVAIERPAFPAALQAVQRLHLKAVEIPVDPHTGLDLDALAEALDTH
HHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHCCC
PVRACWFMTSLHNPTGATLSDERKRALIELLAAHRVPLIEDDVYGELQFGPAPVRPAKVY
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCEEE
DDSGLVLHCGSFSKCLAPGFRIGWVAAGRYARQIRQANCMGTPSADVPAQLAISSYLGHG
CCCCCEEECCCCHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCC
GYDRFLRKLRRNLAAHQAQMVAAVHAYFPQGTEVFAPGGGYFLWIELPKRVDALRLFGAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCHHHHHHHHHHHH
LENGISIAPGPIFSATGGFRRYVRLNYGRPWTPAVENAMQTIGTLAARQRHPE
HHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKRYAALAQTIADSIRRGDLAPGERIPTVRAACRAYRVSPSTVFRAYYQLESEGLIVARP
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEECC
RSGYFVANLDASRLRSTLDPLRKPAAAPHVAETALCRLLDSLKHGDVVPLGSAFANYSLF
CCCEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCC
PMSSLWRYVQSATRNMDRVTMLSGLPPGEDGLRRQIALRYLTAGAALPMDEIIVTTGALD
CHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ALMLSLQALTRPGEVVAIERPAFPAALQAVQRLHLKAVEIPVDPHTGLDLDALAEALDTH
HHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHCCC
PVRACWFMTSLHNPTGATLSDERKRALIELLAAHRVPLIEDDVYGELQFGPAPVRPAKVY
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCEEE
DDSGLVLHCGSFSKCLAPGFRIGWVAAGRYARQIRQANCMGTPSADVPAQLAISSYLGHG
CCCCCEEECCCCHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCC
GYDRFLRKLRRNLAAHQAQMVAAVHAYFPQGTEVFAPGGGYFLWIELPKRVDALRLFGAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCHHHHHHHHHHHH
LENGISIAPGPIFSATGGFRRYVRLNYGRPWTPAVENAMQTIGTLAARQRHPE
HHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]