BacMap

Definition	Burkholderia multivorans ATCC 17616 chromosome 2, complete genome.
Accession	NC_010805
Length	2,473,162

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The map label for this gene is fabG [H]

Identifier: 189353677

GI number: 189353677

Start: 1940331

End: 1941095

Strand: Reverse

Name: fabG [H]

Synonym: BMULJ_04922

Alternate gene names: 189353677

Gene position: 1941095-1940331 (Counterclockwise)

Preceding gene: 189353680

Following gene: 189353676

Centisome position: 78.49

GC content: 70.33

Gene sequence:

>765_bases
ATGAGATTGCAGGGCAAACGCGCGCTGGTCACGGCCGCCGGTCAGGGCATCGGCCGCGCGACCGCGCTGCGCTTCGCGCG
CGAAGGCGCCGACGTACTGGCGACGGACATCGACGAAGCCGCACTCGCGCGGCTCGCGGCCGACGCCGACGCGGCCGGCA
CGCGCGTCACCACGCGCCGGCTCGACGTGACCGACGCGACCGCGATCACGGCGCTGGCGGCAGCCGAACCCGCGTTCGAC
GTGCTGTTCAACTGCGCGGGCTACGTCCATCACGGCTCGATCCTCGACTGCGACGACGCGGCATGGACCTTCTCGTGGCA
ACTGAACGTCACGTCGATGTACCGGCTCGCTCGCGCGCTGCTGCCCGCGATGATCGCGGCCGGTGGCGCGTCGATCGTCA
ACATGGCCTCGGCCGCCTCGAGCGTGAAGGGCGTGCCGAACCGCTTCGTCTACGGGACGACGAAAGCGGCCGTGATCGGC
CTCACGAAGTCGATCGCCGCCGATTTCGTCGAGCAGCGCATTCGTTGCAACGCGATCTGCCCGGGCACGATCGAGTCGCC
GTCGCTCGAGCAGCGGATCGCCGAGCAGGCGCGCGCGCGGCAGGTGCCGGTCGACACCGTGCGACAGGCGTTCGTCGCGC
GTCAGCCGATGGGCCGCATCGGCAGCCCGGACGAAGTCGCGGCGCTCGCGCTGTATCTGGCCTCCGACGAGTCGTCGTTC
ACGACGGGCGCGATTCATCTGATCGACGGCGGCTGGTCCAACTGA

Upstream 100 bases:

>100_bases
ACAAACGCGGAATCGCTTCCTATGATTGGTTGGACCTTTGGTCCATTGCGCCAATGTACGGCGGTCGACGGGCGTTGGCG
ACGTCATCGGAGGGTGGCTC

Downstream 100 bases:

>100_bases
CCGTTCCCATTCTCCTTTCCTGTTGACGCGACATGAAACTGCTCAGATTCGGCGACAAACATCGTGAAAAACCGGGCTTG
CTCGATGCGCACGGACAGAT

Product: putative short-chain alcohol dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MRLQGKRALVTAAGQGIGRATALRFAREGADVLATDIDEAALARLAADADAAGTRVTTRRLDVTDATAITALAAAEPAFD
VLFNCAGYVHHGSILDCDDAAWTFSWQLNVTSMYRLARALLPAMIAAGGASIVNMASAASSVKGVPNRFVYGTTKAAVIG
LTKSIAADFVEQRIRCNAICPGTIESPSLEQRIAEQARARQVPVDTVRQAFVARQPMGRIGSPDEVAALALYLASDESSF
TTGAIHLIDGGWSN

Sequences:

>Translated_254_residues
MRLQGKRALVTAAGQGIGRATALRFAREGADVLATDIDEAALARLAADADAAGTRVTTRRLDVTDATAITALAAAEPAFD
VLFNCAGYVHHGSILDCDDAAWTFSWQLNVTSMYRLARALLPAMIAAGGASIVNMASAASSVKGVPNRFVYGTTKAAVIG
LTKSIAADFVEQRIRCNAICPGTIESPSLEQRIAEQARARQVPVDTVRQAFVARQPMGRIGSPDEVAALALYLASDESSF
TTGAIHLIDGGWSN
>Mature_254_residues
MRLQGKRALVTAAGQGIGRATALRFAREGADVLATDIDEAALARLAADADAAGTRVTTRRLDVTDATAITALAAAEPAFD
VLFNCAGYVHHGSILDCDDAAWTFSWQLNVTSMYRLARALLPAMIAAGGASIVNMASAASSVKGVPNRFVYGTTKAAVIG
LTKSIAADFVEQRIRCNAICPGTIESPSLEQRIAEQARARQVPVDTVRQAFVARQPMGRIGSPDEVAALALYLASDESSF
TTGAIHLIDGGWSN

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI66933014, Length=252, Percent_Identity=53.968253968254, Blast_Score=253, Evalue=1e-67,
Organism=Homo sapiens, GI15277342, Length=264, Percent_Identity=31.4393939393939, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=28.740157480315, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI7705925, Length=252, Percent_Identity=28.968253968254, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI142976729, Length=196, Percent_Identity=30.1020408163265, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI126723750, Length=258, Percent_Identity=25.1937984496124, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI10190704, Length=263, Percent_Identity=30.0380228136882, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI59889578, Length=233, Percent_Identity=30.9012875536481, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI19923817, Length=261, Percent_Identity=25.2873563218391, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI40807363, Length=196, Percent_Identity=31.6326530612245, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=25.8064516129032, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI210032110, Length=196, Percent_Identity=25, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=27.6422764227642, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI31542939, Length=213, Percent_Identity=27.6995305164319, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI4504505, Length=263, Percent_Identity=26.615969581749, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=38.9763779527559, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI1787335, Length=256, Percent_Identity=31.640625, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787905, Length=255, Percent_Identity=31.3725490196078, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1789208, Length=257, Percent_Identity=30.3501945525292, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1789378, Length=257, Percent_Identity=30.3501945525292, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=29.4117647058824, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=27.8884462151394, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=25.5905511811024, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082160, Length=267, Percent_Identity=25.0936329588015, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI2367365, Length=250, Percent_Identity=27.6, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=29.9212598425197, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787820, Length=186, Percent_Identity=30.1075268817204, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789057, Length=251, Percent_Identity=25.4980079681275, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786701, Length=235, Percent_Identity=24.6808510638298, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=256, Percent_Identity=31.640625, Blast_Score=114, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=31.3725490196078, Blast_Score=110, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI71994604, Length=258, Percent_Identity=34.4961240310078, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17561402, Length=268, Percent_Identity=30.2238805970149, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71994600, Length=260, Percent_Identity=31.9230769230769, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=28.90625, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=28.968253968254, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=274, Percent_Identity=29.5620437956204, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=27.7486910994764, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=267, Percent_Identity=28.0898876404494, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=271, Percent_Identity=28.4132841328413, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=26.615969581749, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=269, Percent_Identity=30.8550185873606, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=192, Percent_Identity=25, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=267, Percent_Identity=27.3408239700375, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=27.6515151515151, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=26.0536398467433, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=266, Percent_Identity=28.9473684210526, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=270, Percent_Identity=27.037037037037, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=26.9372693726937, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=190, Percent_Identity=25.2631578947368, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=271, Percent_Identity=26.9372693726937, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=270, Percent_Identity=27.4074074074074, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=266, Percent_Identity=27.8195488721804, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=25.6410256410256, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=26.2357414448669, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=255, Percent_Identity=26.2745098039216, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=272, Percent_Identity=27.2058823529412, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=221, Percent_Identity=28.9592760180996, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639444, Length=258, Percent_Identity=32.5581395348837, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI23397609, Length=256, Percent_Identity=33.59375, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=28.7937743190661, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24643142, Length=251, Percent_Identity=29.8804780876494, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI21357041, Length=256, Percent_Identity=29.6875, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=30.46875, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=27.734375, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24644337, Length=258, Percent_Identity=32.9457364341085, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI17737361, Length=274, Percent_Identity=29.9270072992701, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI18859837, Length=191, Percent_Identity=27.2251308900524, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26651; Mature: 26651

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLQGKRALVTAAGQGIGRATALRFAREGADVLATDIDEAALARLAADADAAGTRVTTRR
CCCCCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHCHHHHHHHHHHHCCCCCCCEEEEEE
LDVTDATAITALAAAEPAFDVLFNCAGYVHHGSILDCDDAAWTFSWQLNVTSMYRLARAL
ECCCHHHHHHHHHHCCHHHHHHHHHHHHEECCCEEECCCCCEEEEEEECHHHHHHHHHHH
LPAMIAAGGASIVNMASAASSVKGVPNRFVYGTTKAAVIGLTKSIAADFVEQRIRCNAIC
HHHHHHCCCHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCC
PGTIESPSLEQRIAEQARARQVPVDTVRQAFVARQPMGRIGSPDEVAALALYLASDESSF
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHEEECCCCCC
TTGAIHLIDGGWSN
EEEEEEEECCCCCC
>Mature Secondary Structure
MRLQGKRALVTAAGQGIGRATALRFAREGADVLATDIDEAALARLAADADAAGTRVTTRR
CCCCCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHCHHHHHHHHHHHCCCCCCCEEEEEE
LDVTDATAITALAAAEPAFDVLFNCAGYVHHGSILDCDDAAWTFSWQLNVTSMYRLARAL
ECCCHHHHHHHHHHCCHHHHHHHHHHHHEECCCEEECCCCCEEEEEEECHHHHHHHHHHH
LPAMIAAGGASIVNMASAASSVKGVPNRFVYGTTKAAVIGLTKSIAADFVEQRIRCNAIC
HHHHHHCCCHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCC
PGTIESPSLEQRIAEQARARQVPVDTVRQAFVARQPMGRIGSPDEVAALALYLASDESSF
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHEEECCCCCC
TTGAIHLIDGGWSN
EEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]