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The map label for this gene is ycgM [C]

Identifier: 189353676

GI number: 189353676

Start: 1939456

End: 1940298

Strand: Reverse

Name: ycgM [C]

Synonym: BMULJ_04921

Alternate gene names: 189353676

Gene position: 1940298-1939456 (Counterclockwise)

Preceding gene: 189353677

Following gene: 189353675

Centisome position: 78.45

GC content: 66.79

Gene sequence:

>843_bases
ATGAAACTGCTCAGATTCGGCGACAAACATCGTGAAAAACCGGGCTTGCTCGATGCGCACGGACAGATCCGCGATCTGTC
CGGCGTAGTCGACGACATCGCCGGCGACGTGCTGCTGCCGGAGTCGCTCGTGCGGCTGCGCGACATACCGCCGTCGTCGT
TGCCGCTCGTCGAAGGTACGCCGCGCATCGGCGCCTGCGTGGGCCGCGTCGGCAAGTTCATCTGCATCGGGCTCAACTAT
TCGGATCACGCGGCCGAGTCGGGCATGGAGGTGCCGAAGGAACCCGTCGTGTTCGGCAAGTGGACGAGCGCGATCTCGGG
GCCGAACGACGACGTCGAGATCCCGCGCGGATCGGAGAAGACCGACTGGGAAGTCGAGCTCGGCGTGGTCATCGGCCGCG
GCGGCCGCTACATCGCCGAAGCCGATGCGCTGTCGCACGTCGCGGGCTACTGCGTCGTCAACGACGTGTCGGAGCGCGAA
TATCAGCTCGAACGCGGCGGCACGTGGGACAAGGGCAAGGGCAACGACACGTTCGGCCCGATCGGGCCGTGGCTCGTGAC
GGCCGACGAAGTGCCCGATCCGCATGCGTTGCGACTGTGGCTCGAGGTCGACGGCCATCGCTATCAGAACGGCACGACCG
CGACGATGGTGTTTCGCGTGCCCTACCTGATCAGCTATCTGAGCCGCTTCATGAGCCTGCAGCCGGGCGACGTGATCTCG
ACCGGCACACCGCCCGGCGTCGGGCTCGGCCAGAAGCCGCCCGTCTATCTGCGTGCCGGGCAGGTGATGACGCTCGGCAT
CGACGGGCTGGGCGAGCAGCGCCAGCGCACGGTACAGGCCTGA

Upstream 100 bases:

>100_bases
TGGCCTCCGACGAGTCGTCGTTCACGACGGGCGCGATTCATCTGATCGACGGCGGCTGGTCCAACTGACCGTTCCCATTC
TCCTTTCCTGTTGACGCGAC

Downstream 100 bases:

>100_bases
TCTTTTTCGCGGACGGTTCCTCATGACGCTCATTCGATCGATACGCGTGCTCGACGTGCGCTTTCCGACCTCGCGCCAGC
TCGACGGCTCCGACGCGATG

Product: putative fumarylacetoacetate hydrolase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MKLLRFGDKHREKPGLLDAHGQIRDLSGVVDDIAGDVLLPESLVRLRDIPPSSLPLVEGTPRIGACVGRVGKFICIGLNY
SDHAAESGMEVPKEPVVFGKWTSAISGPNDDVEIPRGSEKTDWEVELGVVIGRGGRYIAEADALSHVAGYCVVNDVSERE
YQLERGGTWDKGKGNDTFGPIGPWLVTADEVPDPHALRLWLEVDGHRYQNGTTATMVFRVPYLISYLSRFMSLQPGDVIS
TGTPPGVGLGQKPPVYLRAGQVMTLGIDGLGEQRQRTVQA

Sequences:

>Translated_280_residues
MKLLRFGDKHREKPGLLDAHGQIRDLSGVVDDIAGDVLLPESLVRLRDIPPSSLPLVEGTPRIGACVGRVGKFICIGLNY
SDHAAESGMEVPKEPVVFGKWTSAISGPNDDVEIPRGSEKTDWEVELGVVIGRGGRYIAEADALSHVAGYCVVNDVSERE
YQLERGGTWDKGKGNDTFGPIGPWLVTADEVPDPHALRLWLEVDGHRYQNGTTATMVFRVPYLISYLSRFMSLQPGDVIS
TGTPPGVGLGQKPPVYLRAGQVMTLGIDGLGEQRQRTVQA
>Mature_280_residues
MKLLRFGDKHREKPGLLDAHGQIRDLSGVVDDIAGDVLLPESLVRLRDIPPSSLPLVEGTPRIGACVGRVGKFICIGLNY
SDHAAESGMEVPKEPVVFGKWTSAISGPNDDVEIPRGSEKTDWEVELGVVIGRGGRYIAEADALSHVAGYCVVNDVSERE
YQLERGGTWDKGKGNDTFGPIGPWLVTADEVPDPHALRLWLEVDGHRYQNGTTATMVFRVPYLISYLSRFMSLQPGDVIS
TGTPPGVGLGQKPPVYLRAGQVMTLGIDGLGEQRQRTVQA

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=286, Percent_Identity=42.3076923076923, Blast_Score=220, Evalue=1e-57,
Organism=Homo sapiens, GI40786394, Length=286, Percent_Identity=41.2587412587413, Blast_Score=210, Evalue=9e-55,
Organism=Homo sapiens, GI66348062, Length=180, Percent_Identity=38.8888888888889, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI215422413, Length=179, Percent_Identity=39.1061452513966, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI13654274, Length=179, Percent_Identity=39.1061452513966, Blast_Score=139, Evalue=3e-33,
Organism=Escherichia coli, GI1787428, Length=203, Percent_Identity=36.9458128078818, Blast_Score=127, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17557057, Length=199, Percent_Identity=35.1758793969849, Blast_Score=134, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6324161, Length=213, Percent_Identity=30.0469483568075, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28572127, Length=209, Percent_Identity=44.9760765550239, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI28571789, Length=204, Percent_Identity=39.2156862745098, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24663695, Length=267, Percent_Identity=29.9625468164794, Blast_Score=141, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 30381; Mature: 30381

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLRFGDKHREKPGLLDAHGQIRDLSGVVDDIAGDVLLPESLVRLRDIPPSSLPLVEGT
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEECHHHHHHHHCCCCCCCCCCCCC
PRIGACVGRVGKFICIGLNYSDHAAESGMEVPKEPVVFGKWTSAISGPNDDVEIPRGSEK
CHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCCCCEEEECHHHHCCCCCCCCCCCCCCCC
TDWEVELGVVIGRGGRYIAEADALSHVAGYCVVNDVSEREYQLERGGTWDKGKGNDTFGP
CCEEEEEEEEEECCCCEEEHHHHHHHHHCEEEEECCHHHHHHHHCCCCCCCCCCCCCCCC
IGPWLVTADEVPDPHALRLWLEVDGHRYQNGTTATMVFRVPYLISYLSRFMSLQPGDVIS
CCCEEEEECCCCCCCEEEEEEEECCEEECCCCEEEEEEHHHHHHHHHHHHHCCCCCCEEE
TGTPPGVGLGQKPPVYLRAGQVMTLGIDGLGEQRQRTVQA
CCCCCCCCCCCCCCEEEECCCEEEEECCCCCHHHHHHCCC
>Mature Secondary Structure
MKLLRFGDKHREKPGLLDAHGQIRDLSGVVDDIAGDVLLPESLVRLRDIPPSSLPLVEGT
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEECHHHHHHHHCCCCCCCCCCCCC
PRIGACVGRVGKFICIGLNYSDHAAESGMEVPKEPVVFGKWTSAISGPNDDVEIPRGSEK
CHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCCCCEEEECHHHHCCCCCCCCCCCCCCCC
TDWEVELGVVIGRGGRYIAEADALSHVAGYCVVNDVSEREYQLERGGTWDKGKGNDTFGP
CCEEEEEEEEEECCCCEEEHHHHHHHHHCEEEEECCHHHHHHHHCCCCCCCCCCCCCCCC
IGPWLVTADEVPDPHALRLWLEVDGHRYQNGTTATMVFRVPYLISYLSRFMSLQPGDVIS
CCCEEEEECCCCCCCEEEEEEEECCEEECCCCEEEEEEHHHHHHHHHHHHHCCCCCCEEE
TGTPPGVGLGQKPPVYLRAGQVMTLGIDGLGEQRQRTVQA
CCCCCCCCCCCCCCEEEECCCEEEEECCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA