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The map label for this gene is iorB [H]

Identifier: 189353657

GI number: 189353657

Start: 1917271

End: 1919520

Strand: Reverse

Name: iorB [H]

Synonym: BMULJ_04902

Alternate gene names: 189353657

Gene position: 1919520-1917271 (Counterclockwise)

Preceding gene: 189353658

Following gene: 189353656

Centisome position: 77.61

GC content: 70.27

Gene sequence:

>2250_bases
ATGCGACACGATCGAACCGCACCGATGCCGCCCATCGACGACGCCCCGCGGCGCCGCTTTCTGAAGCAGAGTGCCGCGCT
GCTCACTGCCGGCGTCGCCGTCGGCTTCCGGCTGGCCGATGCAACGGCGGCCGGCCCACGCGCGAGCGGCGACCCGCATC
CGGCCGCCGGCGAATTCGAGCCGAACGCATGGGTGCGCGTGCTCCCTGACGACACGATCAAGCTCGTCGTGCACAAGCAC
GATTCGGGCACCGGCACGCGCACCGCGCTCGCGGCGCTCGTCGCGGAGGAGCTGGACGTCGATCCGTTCAGGGTTGAGGT
CATCACGCCTGAGGATCCGTTCTTCGCCGACTACATCCATCCGTTGTGGAAGGTGTTCTCGACCGGCGGCAGCACGAGCG
TCGCGATGGAGTACGACCGGCTGCGCGAGGCGGGCGCGACTGCGCGCGCGATGCTCGTCGCAGCGGCCGCGCGGCAATGG
AACGTGCGCGCGTCGACGTGTACAACGGCCGACGGCGCCGTGCAGCATGCGGCGAGCGGACGCCGCGCGACGTACGGATC
GCTCGCGTCGGCTGCCGCACGGTTGCCGGCGCCGCAGCGTGTCGCGCTGAAGGACCCCGCGCAATTCCGCTATATCGGCA
AGCTGCGGCGCAAGCGCGGCGCCGCGCAAAAGGCCGACGGATCGTTTCCGTACAGCATCGACGTATCGCTGCCGGGGATG
CTGGTCGCCGTCGTCACGCGCGCGCCGGTGATCGACGCACGCGTGCGCAGCGTCGACGCGAAGGCCGCGCTCGCGATGCC
CGGCGTGCGCGACGTGCTGCAGATCCCGCCGCGCCCCGACGTGCTCGGCGGCAATCAGGCCGGCGTCGCGGTGCTGGCCG
ACGACTACTGGTCCGCGCATCGTGCGCAGGCCGCGCTGAAGATCGAATGGGAGGACAGCCTGTTCGAGACCTTCGACAGC
AGCACGTTGGCCGCGCGGCAGGCCGCGTGGGTCGACGATCCGGCCGCGCGCGTCGTGCCGACGATCCGCGACGGCGATCC
CGCGAACGCGTCGCTCGCGGGCGCGCGCACGGTCGACGCGACCTATGCGATGCCGTACAAGGCCGCGAATCCGCTCGAGC
CGATCAACGTGACCGTATGGGCGCGCGACGGCGGAATCGAATACTGGGGCGGGCTGCAGGTGCCGTCCACGGCAATGGAG
GCCGCTCAGGTGATCGGCGGTATTCCCGCGCACCGCGTGACGCTGCATGAGCGCGTATCGGGCGGCAGTTTCGGCGCGCG
CGAATCGAAGTACTGGCTGTTCGAGGCGACCTGGCTCGCGGTGAAGACCGGCAAGCCGGTGAAGCTGATGAACAGCCGCG
AGGACGAGATGCGCGCGCTGTTCTATCACGCGGCAAGCTGTCACCGCGCACGCGCGGTGCTCGACGCGCGCGGCAATCTC
GCGTCGCTGTGGCTGCGCGGCGTGATGCCCGCTTCGCCGCAACAATGGGAGCCCGGCTATCTCGAGCGCGCGGACCGCAT
GGACTTCAGCACGACCGAGGCGCTCACCAAATGGGAGTTCGCCTATGCGGCGCCGCATCGCGACATCGGCTGGATTCGTC
TGGAGACCGGCGTGCCGACCGGCTGGTATCGCGCGGTCAGCTATATCCCGAACGTGTTCGCGGTCGAGTCGCTGATGGAC
GAGGCGGCGCATGCGGCCGCGCGCGACCCCGTCGAATTCCGGCTCGCGCACATGCGCGACCGCCCGCGGCACGCGGCCGT
GCTGCGCGAGGCCGCGACGCGCGCCGGCTGGGGGCAGCCGCTGCCGGCCGGCGTCGCGCTCGGCATCGCGACAAATCAGG
CCTACGACAGCTACGTCGCGGTGGTCGCGCGGGTCGTTCGCGACGCCGAGGGCGCGGTGCGGGTCGCGAAGCTCACGTGC
GTCGCCGACTGCGGGATCGCGGTGTCGCCGGCCGGCGTCGAGGAGCAGCTGTACGGGGGGCTGATGTGGGGGCTCGGCCA
CGCGACGTCCGACCGCATCGACATCCGCAACGGCCGCGTGCAGCAGTCGAACTTCGACACGTATCGCGTGATGCGCATGA
ACGACATGCCGGAAACCGACATTCACATCGTGCAGGGCGACCGCGCGAAGCCAGGCGGTGTCGGGGAGCTCTCGAGTCCT
GCCGTTACGCCGGCGATCGCGAACGCGGTGTTCCGATTGAGCGGCAAACGGTTGCGTGAGACACCGTTCGATTTGTCGGC
GGTTTCGTAG

Upstream 100 bases:

>100_bases
CGGTGCGGCACCTATGCGGGCATCCATCGCGCGATCAAGCGCGCGGCGTCGGGCGATCCCGCGCTCGACGCGGTGGCCGG
CGACGCCAAGGAGGCATGAG

Downstream 100 bases:

>100_bases
CGCGCGAAACGATCGCGGTGGATCGCGCATCGTGCATCGCGCGTGCGGGCGGCGCCGATGAACGTATGAAGTTTGACGCA
CATCTGCGCTCAATCCGCTG

Product: isoquinoline 1-oxidoreductase, beta subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 749; Mature: 749

Protein sequence:

>749_residues
MRHDRTAPMPPIDDAPRRRFLKQSAALLTAGVAVGFRLADATAAGPRASGDPHPAAGEFEPNAWVRVLPDDTIKLVVHKH
DSGTGTRTALAALVAEELDVDPFRVEVITPEDPFFADYIHPLWKVFSTGGSTSVAMEYDRLREAGATARAMLVAAAARQW
NVRASTCTTADGAVQHAASGRRATYGSLASAAARLPAPQRVALKDPAQFRYIGKLRRKRGAAQKADGSFPYSIDVSLPGM
LVAVVTRAPVIDARVRSVDAKAALAMPGVRDVLQIPPRPDVLGGNQAGVAVLADDYWSAHRAQAALKIEWEDSLFETFDS
STLAARQAAWVDDPAARVVPTIRDGDPANASLAGARTVDATYAMPYKAANPLEPINVTVWARDGGIEYWGGLQVPSTAME
AAQVIGGIPAHRVTLHERVSGGSFGARESKYWLFEATWLAVKTGKPVKLMNSREDEMRALFYHAASCHRARAVLDARGNL
ASLWLRGVMPASPQQWEPGYLERADRMDFSTTEALTKWEFAYAAPHRDIGWIRLETGVPTGWYRAVSYIPNVFAVESLMD
EAAHAAARDPVEFRLAHMRDRPRHAAVLREAATRAGWGQPLPAGVALGIATNQAYDSYVAVVARVVRDAEGAVRVAKLTC
VADCGIAVSPAGVEEQLYGGLMWGLGHATSDRIDIRNGRVQQSNFDTYRVMRMNDMPETDIHIVQGDRAKPGGVGELSSP
AVTPAIANAVFRLSGKRLRETPFDLSAVS

Sequences:

>Translated_749_residues
MRHDRTAPMPPIDDAPRRRFLKQSAALLTAGVAVGFRLADATAAGPRASGDPHPAAGEFEPNAWVRVLPDDTIKLVVHKH
DSGTGTRTALAALVAEELDVDPFRVEVITPEDPFFADYIHPLWKVFSTGGSTSVAMEYDRLREAGATARAMLVAAAARQW
NVRASTCTTADGAVQHAASGRRATYGSLASAAARLPAPQRVALKDPAQFRYIGKLRRKRGAAQKADGSFPYSIDVSLPGM
LVAVVTRAPVIDARVRSVDAKAALAMPGVRDVLQIPPRPDVLGGNQAGVAVLADDYWSAHRAQAALKIEWEDSLFETFDS
STLAARQAAWVDDPAARVVPTIRDGDPANASLAGARTVDATYAMPYKAANPLEPINVTVWARDGGIEYWGGLQVPSTAME
AAQVIGGIPAHRVTLHERVSGGSFGARESKYWLFEATWLAVKTGKPVKLMNSREDEMRALFYHAASCHRARAVLDARGNL
ASLWLRGVMPASPQQWEPGYLERADRMDFSTTEALTKWEFAYAAPHRDIGWIRLETGVPTGWYRAVSYIPNVFAVESLMD
EAAHAAARDPVEFRLAHMRDRPRHAAVLREAATRAGWGQPLPAGVALGIATNQAYDSYVAVVARVVRDAEGAVRVAKLTC
VADCGIAVSPAGVEEQLYGGLMWGLGHATSDRIDIRNGRVQQSNFDTYRVMRMNDMPETDIHIVQGDRAKPGGVGELSSP
AVTPAIANAVFRLSGKRLRETPFDLSAVS
>Mature_749_residues
MRHDRTAPMPPIDDAPRRRFLKQSAALLTAGVAVGFRLADATAAGPRASGDPHPAAGEFEPNAWVRVLPDDTIKLVVHKH
DSGTGTRTALAALVAEELDVDPFRVEVITPEDPFFADYIHPLWKVFSTGGSTSVAMEYDRLREAGATARAMLVAAAARQW
NVRASTCTTADGAVQHAASGRRATYGSLASAAARLPAPQRVALKDPAQFRYIGKLRRKRGAAQKADGSFPYSIDVSLPGM
LVAVVTRAPVIDARVRSVDAKAALAMPGVRDVLQIPPRPDVLGGNQAGVAVLADDYWSAHRAQAALKIEWEDSLFETFDS
STLAARQAAWVDDPAARVVPTIRDGDPANASLAGARTVDATYAMPYKAANPLEPINVTVWARDGGIEYWGGLQVPSTAME
AAQVIGGIPAHRVTLHERVSGGSFGARESKYWLFEATWLAVKTGKPVKLMNSREDEMRALFYHAASCHRARAVLDARGNL
ASLWLRGVMPASPQQWEPGYLERADRMDFSTTEALTKWEFAYAAPHRDIGWIRLETGVPTGWYRAVSYIPNVFAVESLMD
EAAHAAARDPVEFRLAHMRDRPRHAAVLREAATRAGWGQPLPAGVALGIATNQAYDSYVAVVARVVRDAEGAVRVAKLTC
VADCGIAVSPAGVEEQLYGGLMWGLGHATSDRIDIRNGRVQQSNFDTYRVMRMNDMPETDIHIVQGDRAKPGGVGELSSP
AVTPAIANAVFRLSGKRLRETPFDLSAVS

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 80906; Mature: 80906

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHDRTAPMPPIDDAPRRRFLKQSAALLTAGVAVGFRLADATAAGPRASGDPHPAAGEFE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCC
PNAWVRVLPDDTIKLVVHKHDSGTGTRTALAALVAEELDVDPFRVEVITPEDPFFADYIH
CCCEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHH
PLWKVFSTGGSTSVAMEYDRLREAGATARAMLVAAAARQWNVRASTCTTADGAVQHAASG
HHHHHHHCCCCCEEEEEHHHHHHCCCHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHCCC
RRATYGSLASAAARLPAPQRVALKDPAQFRYIGKLRRKRGAAQKADGSFPYSIDVSLPGM
CCCCHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHH
LVAVVTRAPVIDARVRSVDAKAALAMPGVRDVLQIPPRPDVLGGNQAGVAVLADDYWSAH
HHHHHHCCCHHHHHHHHCCCHHHHCCCCHHHHHCCCCCCCCCCCCCCCEEEEECCHHHHH
RAQAALKIEWEDSLFETFDSSTLAARQAAWVDDPAARVVPTIRDGDPANASLAGARTVDA
HCCEEEEEEECHHHHHHHCCCHHHHHHHCCCCCCHHHCCCEECCCCCCCCCCCCCEECCC
TYAMPYKAANPLEPINVTVWARDGGIEYWGGLQVPSTAMEAAQVIGGIPAHRVTLHERVS
EEECCCCCCCCCCCCEEEEEEECCCEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEHHCC
GGSFGARESKYWLFEATWLAVKTGKPVKLMNSREDEMRALFYHAASCHRARAVLDARGNL
CCCCCCCCCEEEEEEEEEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
ASLWLRGVMPASPQQWEPGYLERADRMDFSTTEALTKWEFAYAAPHRDIGWIRLETGVPT
HHHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHEEEECCCCCCCEEEEECCCCH
GWYRAVSYIPNVFAVESLMDEAAHAAARDPVEFRLAHMRDRPRHAAVLREAATRAGWGQP
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCC
LPAGVALGIATNQAYDSYVAVVARVVRDAEGAVRVAKLTCVADCGIAVSPAGVEEQLYGG
CCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCEECCCCCHHHHHHH
LMWGLGHATSDRIDIRNGRVQQSNFDTYRVMRMNDMPETDIHIVQGDRAKPGGVGELSSP
HHHHCCCCCCCCEECCCCEEECCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCC
AVTPAIANAVFRLSGKRLRETPFDLSAVS
CCCHHHHHHHHHHCCCHHHCCCCCCCCCC
>Mature Secondary Structure
MRHDRTAPMPPIDDAPRRRFLKQSAALLTAGVAVGFRLADATAAGPRASGDPHPAAGEFE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCC
PNAWVRVLPDDTIKLVVHKHDSGTGTRTALAALVAEELDVDPFRVEVITPEDPFFADYIH
CCCEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHH
PLWKVFSTGGSTSVAMEYDRLREAGATARAMLVAAAARQWNVRASTCTTADGAVQHAASG
HHHHHHHCCCCCEEEEEHHHHHHCCCHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHCCC
RRATYGSLASAAARLPAPQRVALKDPAQFRYIGKLRRKRGAAQKADGSFPYSIDVSLPGM
CCCCHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHH
LVAVVTRAPVIDARVRSVDAKAALAMPGVRDVLQIPPRPDVLGGNQAGVAVLADDYWSAH
HHHHHHCCCHHHHHHHHCCCHHHHCCCCHHHHHCCCCCCCCCCCCCCCEEEEECCHHHHH
RAQAALKIEWEDSLFETFDSSTLAARQAAWVDDPAARVVPTIRDGDPANASLAGARTVDA
HCCEEEEEEECHHHHHHHCCCHHHHHHHCCCCCCHHHCCCEECCCCCCCCCCCCCEECCC
TYAMPYKAANPLEPINVTVWARDGGIEYWGGLQVPSTAMEAAQVIGGIPAHRVTLHERVS
EEECCCCCCCCCCCCEEEEEEECCCEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEHHCC
GGSFGARESKYWLFEATWLAVKTGKPVKLMNSREDEMRALFYHAASCHRARAVLDARGNL
CCCCCCCCCEEEEEEEEEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
ASLWLRGVMPASPQQWEPGYLERADRMDFSTTEALTKWEFAYAAPHRDIGWIRLETGVPT
HHHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHEEEECCCCCCCEEEEECCCCH
GWYRAVSYIPNVFAVESLMDEAAHAAARDPVEFRLAHMRDRPRHAAVLREAATRAGWGQP
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCC
LPAGVALGIATNQAYDSYVAVVARVVRDAEGAVRVAKLTCVADCGIAVSPAGVEEQLYGG
CCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCEECCCCCHHHHHHH
LMWGLGHATSDRIDIRNGRVQQSNFDTYRVMRMNDMPETDIHIVQGDRAKPGGVGELSSP
HHHHCCCCCCCCEECCCCEEECCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCC
AVTPAIANAVFRLSGKRLRETPFDLSAVS
CCCHHHHHHHHHHCCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]