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The map label for this gene is acoR [H]

Identifier: 189353631

GI number: 189353631

Start: 1890801

End: 1892720

Strand: Direct

Name: acoR [H]

Synonym: BMULJ_04875

Alternate gene names: 189353631

Gene position: 1890801-1892720 (Clockwise)

Preceding gene: 189353628

Following gene: 189353632

Centisome position: 76.45

GC content: 70.52

Gene sequence:

>1920_bases
ATGCCTCAATCTTCCATGCTGCCCGCCACCGCGGGCCGCGTCGACCTGCTCGCGCAGGCGCACGCCCGATCGGCCGCGGT
CGGCTTGCGCGCGCACGAGCGCCCCGATTTCTCGCCGCTGTCGCAGATCGCGCTGCGCGAACTGCTCGACACGAATCACG
CGCTGTTCGCCCATGCACGGCCCGTGATGGAAAACCTCCACGCACAGATCGCCGATACGCAAAGCCTCGTGCTCCTCACC
GACGCCGCTGGCGTCATCCTGCACAGCATCGGCGACGACGACTTCATCGAAAAAGCCAACCGCGTCGCACTGTGCACCGG
CGTTTCGTGGGCCGAACGCGCGCGCGGCACCAATGCGATCGGCACCGCACTCGCGTCGGGACAGGCGATCGCCGTGCACG
GCGCCGAGCATTTCCTGCGCGCCAATCACATCCTGACGTGCTCGTGCGCGCCGATCGTCGATCCGTTCGGCCGCACGCTC
GGCGCGCTCGACGTGAGCGGCGATCCGCGCGGCTTCAGCCCGCATACGCTCGCGCTCGTGCGCATGTCCGCGCAGCTGAT
CGAGAACCATCTGTTTGCGAACCAGTGCGCCGAAGCGCTGCGCGTACGCTTTCATGCACACGAGGATTGCGTCGACTCGC
TGTTCGCCGGCCTCGTCGCGTTCGGTGCCGACGGCGGCCTGATTGCCGCGAACCGAAGCGCGCAGTTTCAGCTCGGCGCA
CCGTTCGATGCGCTGCAGCATCAGGGGTGCGACGCGCTGTTCGGCATGCGATTCGGCGAACTCGCGCAGCAGGCCGCGCG
CGCGCCCGGCGCAGTGCTGCGGCTCACGCTGGCGAGCGGCGTGCGCGTGCTGGCGCGCTGCGAATTCGCCGACGCGCAAA
AAACCGCCGTGGCCGTCACGCCGCCGGCGCCCGCGACACACGTGCGCGCGCCGGACCCGGAGGCAATCACGTTCGCGACG
CTCGATACCGGCGACGCGCGAATGGCCGCCGTGCTCGAACGCGTCGCGAAAATTCGCGGCCGCGACCTGCCGCTGCTGAT
CCTCGGCCAGACCGGCACCGGCAAGGAGTGGCTCGCCCGCGCGCTGCACCACGCGTCGCCGCGCGCGGACGGCCCGTTCG
TCGCGGTCAACTGCGCGGCGCTGCCCGATACGCTGATCGAGGCCGAATTGTTCGGCTACGAAGACGGCGCATTCACGGGC
GCGCGCAAACGCGGCAGTCCCGGCAAGATCGTGCAGGCCGACGGCGGCACGCTGTTTCTCGACGAAATCGGCGACATGCC
GCTCGCGCAGCAGGTGCGGCTCATGCGCGTACTGCAGGAACGCGCGGTAATGCCGCTCGGCGGCGCGCGCGCGGTGCCGG
TCGACGTGCGCATCGTCTGCGCGACGCACCGCGACCTGCGCGCAATGATCGCGGCCGGCACGTTCCGCGAGGATCTGTTC
TACCGGATCAACGGCCTCGCCGTCACGCTGCCGCCGCTCGCCGCCCGCACCGACCTGCCGGTGCTCGTCGAGCGGATCCT
CGCGCGGCTCGCACGCAGCGAACCCATGCCGCACCGCATCGCGCCCGACGTGCTCGACGCATTCACGCGTCATCGCTGGC
CCGGCAATCTGCGTCAGCTGACGAACGTGCTGCGCACGGCCGGCATGCTCGCCGAGGACGAAGACGAAATCGCACTCGCG
CATCTGCCCGACGATTTCTGGCTCGACTGCGACGGCGCGCCGGCAGCCGCATCGGCTGCATCGGTGGCAGCGGCTCCGTC
GACCATACCGCCCGCCCCGCGCGGCACGACGACGCTGCAGGACCACCAGGCCGCCGTGATCGATGCGGCGGTCGCGCGAC
ACGGCGGTAACGTGTCGGCGGCCGCGCGCGAACTGGGGCTCGCCCGCAACACGGTGTACCGCTACCTGCGCCGCCACTGA

Upstream 100 bases:

>100_bases
TGAAGCACCGGTATGGGTGAAAGCGCTGGGTGGTGGACGCGTGGTGCGTGGGGCCCCGGTAAGCGCTAAAGCGCTAACCG
GGGCCGACAGGAGACAAGCG

Downstream 100 bases:

>100_bases
CCGCCGCGGCGGTGCAGGCGGCGCACGGCTTCGGGTATGCTTGGCGCGTTTCCGCCGAACCGATGCCCGCTTTACCGATG
ACCGATTCCGATCGCCCTCC

Product: sigma54-dependent DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 639; Mature: 638

Protein sequence:

>639_residues
MPQSSMLPATAGRVDLLAQAHARSAAVGLRAHERPDFSPLSQIALRELLDTNHALFAHARPVMENLHAQIADTQSLVLLT
DAAGVILHSIGDDDFIEKANRVALCTGVSWAERARGTNAIGTALASGQAIAVHGAEHFLRANHILTCSCAPIVDPFGRTL
GALDVSGDPRGFSPHTLALVRMSAQLIENHLFANQCAEALRVRFHAHEDCVDSLFAGLVAFGADGGLIAANRSAQFQLGA
PFDALQHQGCDALFGMRFGELAQQAARAPGAVLRLTLASGVRVLARCEFADAQKTAVAVTPPAPATHVRAPDPEAITFAT
LDTGDARMAAVLERVAKIRGRDLPLLILGQTGTGKEWLARALHHASPRADGPFVAVNCAALPDTLIEAELFGYEDGAFTG
ARKRGSPGKIVQADGGTLFLDEIGDMPLAQQVRLMRVLQERAVMPLGGARAVPVDVRIVCATHRDLRAMIAAGTFREDLF
YRINGLAVTLPPLAARTDLPVLVERILARLARSEPMPHRIAPDVLDAFTRHRWPGNLRQLTNVLRTAGMLAEDEDEIALA
HLPDDFWLDCDGAPAAASAASVAAAPSTIPPAPRGTTTLQDHQAAVIDAAVARHGGNVSAAARELGLARNTVYRYLRRH

Sequences:

>Translated_639_residues
MPQSSMLPATAGRVDLLAQAHARSAAVGLRAHERPDFSPLSQIALRELLDTNHALFAHARPVMENLHAQIADTQSLVLLT
DAAGVILHSIGDDDFIEKANRVALCTGVSWAERARGTNAIGTALASGQAIAVHGAEHFLRANHILTCSCAPIVDPFGRTL
GALDVSGDPRGFSPHTLALVRMSAQLIENHLFANQCAEALRVRFHAHEDCVDSLFAGLVAFGADGGLIAANRSAQFQLGA
PFDALQHQGCDALFGMRFGELAQQAARAPGAVLRLTLASGVRVLARCEFADAQKTAVAVTPPAPATHVRAPDPEAITFAT
LDTGDARMAAVLERVAKIRGRDLPLLILGQTGTGKEWLARALHHASPRADGPFVAVNCAALPDTLIEAELFGYEDGAFTG
ARKRGSPGKIVQADGGTLFLDEIGDMPLAQQVRLMRVLQERAVMPLGGARAVPVDVRIVCATHRDLRAMIAAGTFREDLF
YRINGLAVTLPPLAARTDLPVLVERILARLARSEPMPHRIAPDVLDAFTRHRWPGNLRQLTNVLRTAGMLAEDEDEIALA
HLPDDFWLDCDGAPAAASAASVAAAPSTIPPAPRGTTTLQDHQAAVIDAAVARHGGNVSAAARELGLARNTVYRYLRRH
>Mature_638_residues
PQSSMLPATAGRVDLLAQAHARSAAVGLRAHERPDFSPLSQIALRELLDTNHALFAHARPVMENLHAQIADTQSLVLLTD
AAGVILHSIGDDDFIEKANRVALCTGVSWAERARGTNAIGTALASGQAIAVHGAEHFLRANHILTCSCAPIVDPFGRTLG
ALDVSGDPRGFSPHTLALVRMSAQLIENHLFANQCAEALRVRFHAHEDCVDSLFAGLVAFGADGGLIAANRSAQFQLGAP
FDALQHQGCDALFGMRFGELAQQAARAPGAVLRLTLASGVRVLARCEFADAQKTAVAVTPPAPATHVRAPDPEAITFATL
DTGDARMAAVLERVAKIRGRDLPLLILGQTGTGKEWLARALHHASPRADGPFVAVNCAALPDTLIEAELFGYEDGAFTGA
RKRGSPGKIVQADGGTLFLDEIGDMPLAQQVRLMRVLQERAVMPLGGARAVPVDVRIVCATHRDLRAMIAAGTFREDLFY
RINGLAVTLPPLAARTDLPVLVERILARLARSEPMPHRIAPDVLDAFTRHRWPGNLRQLTNVLRTAGMLAEDEDEIALAH
LPDDFWLDCDGAPAAASAASVAAAPSTIPPAPRGTTTLQDHQAAVIDAAVARHGGNVSAAARELGLARNTVYRYLRRH

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=323, Percent_Identity=40.2476780185758, Blast_Score=238, Evalue=1e-63,
Organism=Escherichia coli, GI1790437, Length=319, Percent_Identity=41.0658307210031, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1788905, Length=344, Percent_Identity=40.406976744186, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI1788550, Length=320, Percent_Identity=38.4375, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1790299, Length=367, Percent_Identity=38.9645776566758, Blast_Score=208, Evalue=9e-55,
Organism=Escherichia coli, GI87082117, Length=226, Percent_Identity=47.787610619469, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1789087, Length=319, Percent_Identity=38.2445141065831, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI87081872, Length=316, Percent_Identity=37.3417721518987, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1786524, Length=310, Percent_Identity=39.6774193548387, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI87082152, Length=229, Percent_Identity=44.1048034934498, Blast_Score=176, Evalue=4e-45,
Organism=Escherichia coli, GI1787583, Length=232, Percent_Identity=40.5172413793103, Blast_Score=176, Evalue=5e-45,
Organism=Escherichia coli, GI87081858, Length=608, Percent_Identity=23.3552631578947, Blast_Score=149, Evalue=6e-37,
Organism=Escherichia coli, GI1789828, Length=250, Percent_Identity=39.6, Blast_Score=132, Evalue=7e-32,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 67996; Mature: 67864

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQSSMLPATAGRVDLLAQAHARSAAVGLRAHERPDFSPLSQIALRELLDTNHALFAHAR
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHH
PVMENLHAQIADTQSLVLLTDAAGVILHSIGDDDFIEKANRVALCTGVSWAERARGTNAI
HHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCHHHHHHCCCEEEEECCCHHHHHCCCCHH
GTALASGQAIAVHGAEHFLRANHILTCSCAPIVDPFGRTLGALDVSGDPRGFSPHTLALV
HHHHHCCCEEEEECHHHHHHCCCEEEEECCHHHCHHHHHHEEEECCCCCCCCCCHHHHHH
RMSAQLIENHLFANQCAEALRVRFHAHEDCVDSLFAGLVAFGADGGLIAANRSAQFQLGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECC
PFDALQHQGCDALFGMRFGELAQQAARAPGAVLRLTLASGVRVLARCEFADAQKTAVAVT
CHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCCCCEEEEC
PPAPATHVRAPDPEAITFATLDTGDARMAAVLERVAKIRGRDLPLLILGQTGTGKEWLAR
CCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHH
ALHHASPRADGPFVAVNCAALPDTLIEAELFGYEDGAFTGARKRGSPGKIVQADGGTLFL
HHHHCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCEEEH
DEIGDMPLAQQVRLMRVLQERAVMPLGGARAVPVDVRIVCATHRDLRAMIAAGTFREDLF
HHHCCCCHHHHHHHHHHHHHHCCCCCCCCEECCEEEEEEEECCHHHHHHHHHCHHHHHHH
YRINGLAVTLPPLAARTDLPVLVERILARLARSEPMPHRIAPDVLDAFTRHRWPGNLRQL
EEECCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHH
TNVLRTAGMLAEDEDEIALAHLPDDFWLDCDGAPAAASAASVAAAPSTIPPAPRGTTTLQ
HHHHHHHCCCCCCCCCEEEEECCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCC
DHQAAVIDAAVARHGGNVSAAARELGLARNTVYRYLRRH
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PQSSMLPATAGRVDLLAQAHARSAAVGLRAHERPDFSPLSQIALRELLDTNHALFAHAR
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHH
PVMENLHAQIADTQSLVLLTDAAGVILHSIGDDDFIEKANRVALCTGVSWAERARGTNAI
HHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCHHHHHHCCCEEEEECCCHHHHHCCCCHH
GTALASGQAIAVHGAEHFLRANHILTCSCAPIVDPFGRTLGALDVSGDPRGFSPHTLALV
HHHHHCCCEEEEECHHHHHHCCCEEEEECCHHHCHHHHHHEEEECCCCCCCCCCHHHHHH
RMSAQLIENHLFANQCAEALRVRFHAHEDCVDSLFAGLVAFGADGGLIAANRSAQFQLGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECC
PFDALQHQGCDALFGMRFGELAQQAARAPGAVLRLTLASGVRVLARCEFADAQKTAVAVT
CHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCCCCEEEEC
PPAPATHVRAPDPEAITFATLDTGDARMAAVLERVAKIRGRDLPLLILGQTGTGKEWLAR
CCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHH
ALHHASPRADGPFVAVNCAALPDTLIEAELFGYEDGAFTGARKRGSPGKIVQADGGTLFL
HHHHCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCEEEH
DEIGDMPLAQQVRLMRVLQERAVMPLGGARAVPVDVRIVCATHRDLRAMIAAGTFREDLF
HHHCCCCHHHHHHHHHHHHHHCCCCCCCCEECCEEEEEEEECCHHHHHHHHHCHHHHHHH
YRINGLAVTLPPLAARTDLPVLVERILARLARSEPMPHRIAPDVLDAFTRHRWPGNLRQL
EEECCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHH
TNVLRTAGMLAEDEDEIALAHLPDDFWLDCDGAPAAASAASVAAAPSTIPPAPRGTTTLQ
HHHHHHHCCCCCCCCCEEEEECCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCC
DHQAAVIDAAVARHGGNVSAAARELGLARNTVYRYLRRH
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]