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The map label for this gene is pbuG [H]

Identifier: 189353628

GI number: 189353628

Start: 1888312

End: 1889613

Strand: Direct

Name: pbuG [H]

Synonym: BMULJ_04872

Alternate gene names: 189353628

Gene position: 1888312-1889613 (Clockwise)

Preceding gene: 189353626

Following gene: 189353631

Centisome position: 76.35

GC content: 64.36

Gene sequence:

>1302_bases
ATGGAATCCATCAAGCGGTATTTCGGCTTCGCTGAAGCCGGCACCGACTTCCGCACCGAAATACTCGCGGGCGTCACCAC
GTTCCTGACGATGGCCTACATCATCTTCGTCAACCCGGCGATCCTCGGCGACGCCGGCATGCCGAAGGAATCCGTGTTCG
TCGCGACCTGCCTCGTCGCGGCGCTGGCATCGCTGATCATGGGGCTGTACGCGAACTATCCGATCGCGTGCGCACCGGGC
ATGGGGCTGAACGCGTATTTCGCGTACACGGTCGTCAAGGGGATGGGCTTCACGTGGCAGGCCGCACTCGGCGCAGTGTT
CATCTCGGGCTGCCTGTTCCTGCTCGTCACGCTGTTCCGCGTGCGCGAGGCGATCGTCAACGGCATTCCGAAATCGCTGC
GCATCTCGATCACGGCCGGCATCGGGCTGTTCCTCGGGATCATCTCGCTGAAGACGTCCGGCGTGATCGTCGGCAACCCG
GCCACGCTCGTGACGCTCGGCGATCTGCACAAGCACGACACGATCCTCGCGATCATCGGCTTCTTCACGATCGTCACGCT
CGATCATCTGCGCGTGCGCGGCGCGATCCTGATCGGCATTCTCGGCGTGACCGTGCTGTCGTTCTTCTTCGGCGACAACC
AGTTCCACGGCGTGTTTTCCGCACCGCCGTCGATCGACGCGACGCTGTTCAAGCTCGACATCGGCGCCGCGCTGTCGACC
GGCATCATCAACGTGATCCTCGTGTTCTTCCTCGTCGAACTGTTCGATGCGACCGGCACGCTGATGGGCGTCGCGAACCG
CGCGGGGCTGCTCGTCGAAGGCAAGATGCACCGTCTGAACAAGGCGCTGCTCGCGGACAGCACCGCGATCGTCGCCGGTT
CGGTGCTCGGCACGTCGTCGACCACCGCCTATATCGAAAGCGCATCGGGCGTGCAGGCCGGCGGCCGCACCGGCGTGACC
GCGATCACGGTCGCAGTGCTGTTCCTCGCATGTCTGTTCATCGCGCCGCTCGCCGGCGTCGTGCCGGCCTATGCGACTGC
ACCCGCACTGCTGTACGTGTCGTGCCTGATGCTGCGCGAAATGGTCGACGTGCCATGGGACGATGCGACCGAAGCCGTGC
CGGCCGCGCTGACGGCGCTGCTGATGCCGTTCACCTATTCGATCGCGAACGGCGTGGCGTTCGGCTTCATCGCGTACGGC
GGCCTCAAGCTGCTGACGGGCCAGGCACGCACGGTCAAGCCGATCGTCTGGATCATCGCAGCCGTGTTCCTGTTCCGCTT
CTTCTATCTCGGCAGCGAGTAA

Upstream 100 bases:

>100_bases
AGCCGAACAATAGTGGCTGGTTACAGTTAGCCGCCGCACGCAGCCTTACAACAATTCGGCACGACAAGCAATACGACAAC
CCGACCGGAGAAACGCCTTC

Downstream 100 bases:

>100_bases
CGGACGCCGGCCGGCACGCGCCGGAGATGGAAAACGAAACGCCACCCCTCGGGTGGCGTTGTCGCTTTGGCGTGCGCAAC
GATGGCCGTGCCGCCTCGGG

Product: xanthine/uracil permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MESIKRYFGFAEAGTDFRTEILAGVTTFLTMAYIIFVNPAILGDAGMPKESVFVATCLVAALASLIMGLYANYPIACAPG
MGLNAYFAYTVVKGMGFTWQAALGAVFISGCLFLLVTLFRVREAIVNGIPKSLRISITAGIGLFLGIISLKTSGVIVGNP
ATLVTLGDLHKHDTILAIIGFFTIVTLDHLRVRGAILIGILGVTVLSFFFGDNQFHGVFSAPPSIDATLFKLDIGAALST
GIINVILVFFLVELFDATGTLMGVANRAGLLVEGKMHRLNKALLADSTAIVAGSVLGTSSTTAYIESASGVQAGGRTGVT
AITVAVLFLACLFIAPLAGVVPAYATAPALLYVSCLMLREMVDVPWDDATEAVPAALTALLMPFTYSIANGVAFGFIAYG
GLKLLTGQARTVKPIVWIIAAVFLFRFFYLGSE

Sequences:

>Translated_433_residues
MESIKRYFGFAEAGTDFRTEILAGVTTFLTMAYIIFVNPAILGDAGMPKESVFVATCLVAALASLIMGLYANYPIACAPG
MGLNAYFAYTVVKGMGFTWQAALGAVFISGCLFLLVTLFRVREAIVNGIPKSLRISITAGIGLFLGIISLKTSGVIVGNP
ATLVTLGDLHKHDTILAIIGFFTIVTLDHLRVRGAILIGILGVTVLSFFFGDNQFHGVFSAPPSIDATLFKLDIGAALST
GIINVILVFFLVELFDATGTLMGVANRAGLLVEGKMHRLNKALLADSTAIVAGSVLGTSSTTAYIESASGVQAGGRTGVT
AITVAVLFLACLFIAPLAGVVPAYATAPALLYVSCLMLREMVDVPWDDATEAVPAALTALLMPFTYSIANGVAFGFIAYG
GLKLLTGQARTVKPIVWIIAAVFLFRFFYLGSE
>Mature_433_residues
MESIKRYFGFAEAGTDFRTEILAGVTTFLTMAYIIFVNPAILGDAGMPKESVFVATCLVAALASLIMGLYANYPIACAPG
MGLNAYFAYTVVKGMGFTWQAALGAVFISGCLFLLVTLFRVREAIVNGIPKSLRISITAGIGLFLGIISLKTSGVIVGNP
ATLVTLGDLHKHDTILAIIGFFTIVTLDHLRVRGAILIGILGVTVLSFFFGDNQFHGVFSAPPSIDATLFKLDIGAALST
GIINVILVFFLVELFDATGTLMGVANRAGLLVEGKMHRLNKALLADSTAIVAGSVLGTSSTTAYIESASGVQAGGRTGVT
AITVAVLFLACLFIAPLAGVVPAYATAPALLYVSCLMLREMVDVPWDDATEAVPAALTALLMPFTYSIANGVAFGFIAYG
GLKLLTGQARTVKPIVWIIAAVFLFRFFYLGSE

Specific function: High-affinity uptake of adenine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790150, Length=431, Percent_Identity=49.8839907192575, Blast_Score=418, Evalue=1e-118,
Organism=Escherichia coli, GI87082309, Length=425, Percent_Identity=48.7058823529412, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI1790499, Length=434, Percent_Identity=38.7096774193548, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI48994909, Length=403, Percent_Identity=36.7245657568238, Blast_Score=236, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45561; Mature: 45561

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS00310 LAMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESIKRYFGFAEAGTDFRTEILAGVTTFLTMAYIIFVNPAILGDAGMPKESVFVATCLVA
CCCHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHHHHH
ALASLIMGLYANYPIACAPGMGLNAYFAYTVVKGMGFTWQAALGAVFISGCLFLLVTLFR
HHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VREAIVNGIPKSLRISITAGIGLFLGIISLKTSGVIVGNPATLVTLGDLHKHDTILAIIG
HHHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCCEEEECCEEEEEECCCCCCHHHHHHHH
FFTIVTLDHLRVRGAILIGILGVTVLSFFFGDNQFHGVFSAPPSIDATLFKLDIGAALST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEEEHHHHHHH
GIINVILVFFLVELFDATGTLMGVANRAGLLVEGKMHRLNKALLADSTAIVAGSVLGTSS
HHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEECHHHHHHHHHHCCCHHHHCCHHCCCCC
TTAYIESASGVQAGGRTGVTAITVAVLFLACLFIAPLAGVVPAYATAPALLYVSCLMLRE
CHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVDVPWDDATEAVPAALTALLMPFTYSIANGVAFGFIAYGGLKLLTGQARTVKPIVWIIA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCHHHHHHHHHH
AVFLFRFFYLGSE
HHHHHHHHHHCCC
>Mature Secondary Structure
MESIKRYFGFAEAGTDFRTEILAGVTTFLTMAYIIFVNPAILGDAGMPKESVFVATCLVA
CCCHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHHHHH
ALASLIMGLYANYPIACAPGMGLNAYFAYTVVKGMGFTWQAALGAVFISGCLFLLVTLFR
HHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VREAIVNGIPKSLRISITAGIGLFLGIISLKTSGVIVGNPATLVTLGDLHKHDTILAIIG
HHHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCCEEEECCEEEEEECCCCCCHHHHHHHH
FFTIVTLDHLRVRGAILIGILGVTVLSFFFGDNQFHGVFSAPPSIDATLFKLDIGAALST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEEEHHHHHHH
GIINVILVFFLVELFDATGTLMGVANRAGLLVEGKMHRLNKALLADSTAIVAGSVLGTSS
HHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEECHHHHHHHHHHCCCHHHHCCHHCCCCC
TTAYIESASGVQAGGRTGVTAITVAVLFLACLFIAPLAGVVPAYATAPALLYVSCLMLRE
CHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVDVPWDDATEAVPAALTALLMPFTYSIANGVAFGFIAYGGLKLLTGQARTVKPIVWIIA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCHHHHHHHHHH
AVFLFRFFYLGSE
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]