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The map label for this gene is paaG [H]

Identifier: 189353613

GI number: 189353613

Start: 1870525

End: 1871316

Strand: Reverse

Name: paaG [H]

Synonym: BMULJ_04857

Alternate gene names: 189353613

Gene position: 1871316-1870525 (Counterclockwise)

Preceding gene: 189353614

Following gene: 189353612

Centisome position: 75.66

GC content: 70.71

Gene sequence:

>792_bases
ATGATCGAACTCGACTATGTCGACGACGGCGCGATCGCGTGCGCGACGCTGAAGCGTCCGCCCGCGAACGCGTTTACCGC
CGACGGGCTGCGGCAACTGCAGGCGTACGTCGCCGAGCTGAACGCGAATGCGCGCGTGCGCGCGCTCGTCATCACCGGCG
ACGGCCCGAAATTCTTCAGCGCCGGCGCCGATCTGAACACGTTCGCCGACGGCGATCGCGCGGTCGCGCGCGAAATGGCC
GCGCGCTTCGGCGCGGCGTTCGAGGCGCTGCACGATGCGCGCTTCGTGACGATCGCGGCGATCAACGGCTATGCGATGGG
CGGCGGGCTCGAATGCGCGCTCGCGTGCGACCTGCGGATCGCCGAGGCGCATGCGCAGATGGCGCTGCCGGAGCCGTCGG
TCGGGCTGCTGCCGTGCGGGCTCGGCACGCAGACGCTGCCCTGGCTCGTCGGCGAAGGATGGGCGAAGAAGATCATCCTG
ACCGGCACGCGCGTCGATGCGCCGACCGCGCTGCGCATCGGCCTCGTCGAAGAGGTGGTCGATACGGGCACGTCGCGCGA
CGCGGCGCTCGCGCTCGCACGCAACGTCGCGCGGCAGAGCCCGCGTGCGGTCGCATCGAGCAAGGAACTGATCGGCCTCG
CGCGCCGCGGCGTACCGCGCAGCGCGGCGCTCGCGGTCGAACGCGAGCGCTTCGTCGACCTGTTCGACACGAACGATCCG
CGCGAAGGCGTGGCCGCGTTTCTCGGCAAGCGCGCACCGCAATGGCAACCCGAAGGAGAGCAGTCACGATGA

Upstream 100 bases:

>100_bases
CGCAGCAGCTGTACCAGACGATGAGCAGCCGCGGCGACGGCCAGCTCGATTTCTCGGCGGTGATCCGCCTGTATCAACCG
GCAACGAAGAAGGACGCGTG

Downstream 100 bases:

>100_bases
GCACGCCGGCCACGAACCAGGATGCCTTCACCGATCCCGCGCAGGACGTGCTGTTTCGCGTGGTGAACCGCGTCGCGTTG
ATCACGCTCAATCGTCCGTC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MIELDYVDDGAIACATLKRPPANAFTADGLRQLQAYVAELNANARVRALVITGDGPKFFSAGADLNTFADGDRAVAREMA
ARFGAAFEALHDARFVTIAAINGYAMGGGLECALACDLRIAEAHAQMALPEPSVGLLPCGLGTQTLPWLVGEGWAKKIIL
TGTRVDAPTALRIGLVEEVVDTGTSRDAALALARNVARQSPRAVASSKELIGLARRGVPRSAALAVERERFVDLFDTNDP
REGVAAFLGKRAPQWQPEGEQSR

Sequences:

>Translated_263_residues
MIELDYVDDGAIACATLKRPPANAFTADGLRQLQAYVAELNANARVRALVITGDGPKFFSAGADLNTFADGDRAVAREMA
ARFGAAFEALHDARFVTIAAINGYAMGGGLECALACDLRIAEAHAQMALPEPSVGLLPCGLGTQTLPWLVGEGWAKKIIL
TGTRVDAPTALRIGLVEEVVDTGTSRDAALALARNVARQSPRAVASSKELIGLARRGVPRSAALAVERERFVDLFDTNDP
REGVAAFLGKRAPQWQPEGEQSR
>Mature_263_residues
MIELDYVDDGAIACATLKRPPANAFTADGLRQLQAYVAELNANARVRALVITGDGPKFFSAGADLNTFADGDRAVAREMA
ARFGAAFEALHDARFVTIAAINGYAMGGGLECALACDLRIAEAHAQMALPEPSVGLLPCGLGTQTLPWLVGEGWAKKIIL
TGTRVDAPTALRIGLVEEVVDTGTSRDAALALARNVARQSPRAVASSKELIGLARRGVPRSAALAVERERFVDLFDTNDP
REGVAAFLGKRAPQWQPEGEQSR

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=251, Percent_Identity=32.2709163346614, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI68989263, Length=191, Percent_Identity=36.6492146596859, Blast_Score=107, Evalue=9e-24,
Organism=Homo sapiens, GI4502327, Length=240, Percent_Identity=33.75, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI20127408, Length=184, Percent_Identity=30.9782608695652, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI213417737, Length=221, Percent_Identity=28.0542986425339, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI157694516, Length=221, Percent_Identity=28.0542986425339, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI31542718, Length=239, Percent_Identity=25.9414225941423, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI261878539, Length=95, Percent_Identity=45.2631578947368, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI62530384, Length=190, Percent_Identity=28.9473684210526, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI37594471, Length=178, Percent_Identity=28.0898876404494, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI70995211, Length=207, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI37594469, Length=178, Percent_Identity=28.0898876404494, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI157694520, Length=192, Percent_Identity=26.5625, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI150378541, Length=254, Percent_Identity=31.1023622047244, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787659, Length=261, Percent_Identity=38.3141762452107, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI221142681, Length=257, Percent_Identity=33.852140077821, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1788682, Length=189, Percent_Identity=38.0952380952381, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1790281, Length=294, Percent_Identity=27.5510204081633, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787660, Length=263, Percent_Identity=32.319391634981, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082183, Length=248, Percent_Identity=24.5967741935484, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788597, Length=250, Percent_Identity=26.4, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17554946, Length=260, Percent_Identity=33.0769230769231, Blast_Score=124, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI25145438, Length=245, Percent_Identity=34.2857142857143, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17540714, Length=231, Percent_Identity=29.8701298701299, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17558304, Length=232, Percent_Identity=30.6034482758621, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17536985, Length=217, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25144276, Length=175, Percent_Identity=33.1428571428571, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17508953, Length=175, Percent_Identity=33.1428571428571, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17508951, Length=175, Percent_Identity=33.1428571428571, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17534483, Length=252, Percent_Identity=27.3809523809524, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17560910, Length=201, Percent_Identity=29.8507462686567, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17540306, Length=259, Percent_Identity=24.3243243243243, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129971, Length=244, Percent_Identity=31.1475409836066, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24653477, Length=244, Percent_Identity=31.1475409836066, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24653139, Length=258, Percent_Identity=31.3953488372093, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24583165, Length=210, Percent_Identity=25.2380952380952, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI19922422, Length=247, Percent_Identity=22.6720647773279, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19921018, Length=183, Percent_Identity=27.3224043715847, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357171, Length=198, Percent_Identity=31.3131313131313, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24650670, Length=192, Percent_Identity=32.2916666666667, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45550169, Length=197, Percent_Identity=27.9187817258883, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19921000, Length=163, Percent_Identity=34.3558282208589, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24583077, Length=163, Percent_Identity=34.3558282208589, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24583079, Length=163, Percent_Identity=34.3558282208589, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 27868; Mature: 27868

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELDYVDDGAIACATLKRPPANAFTADGLRQLQAYVAELNANARVRALVITGDGPKFFS
CEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEE
AGADLNTFADGDRAVAREMAARFGAAFEALHDARFVTIAAINGYAMGGGLECALACDLRI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCEEECCCCEEEEEECEEE
AEAHAQMALPEPSVGLLPCGLGTQTLPWLVGEGWAKKIILTGTRVDAPTALRIGLVEEVV
EHHHHHHCCCCCCCCEEECCCCCCCHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHH
DTGTSRDAALALARNVARQSPRAVASSKELIGLARRGVPRSAALAVERERFVDLFDTNDP
HCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEECCCCCC
REGVAAFLGKRAPQWQPEGEQSR
HHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MIELDYVDDGAIACATLKRPPANAFTADGLRQLQAYVAELNANARVRALVITGDGPKFFS
CEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEE
AGADLNTFADGDRAVAREMAARFGAAFEALHDARFVTIAAINGYAMGGGLECALACDLRI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCEEECCCCEEEEEECEEE
AEAHAQMALPEPSVGLLPCGLGTQTLPWLVGEGWAKKIILTGTRVDAPTALRIGLVEEVV
EHHHHHHCCCCCCCCEEECCCCCCCHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHH
DTGTSRDAALALARNVARQSPRAVASSKELIGLARRGVPRSAALAVERERFVDLFDTNDP
HCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEECCCCCC
REGVAAFLGKRAPQWQPEGEQSR
HHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]