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The map label for this gene is rstB [H]

Identifier: 189353595

GI number: 189353595

Start: 1849860

End: 1850990

Strand: Reverse

Name: rstB [H]

Synonym: BMULJ_04839

Alternate gene names: 189353595

Gene position: 1850990-1849860 (Counterclockwise)

Preceding gene: 189353596

Following gene: 189353591

Centisome position: 74.84

GC content: 66.05

Gene sequence:

>1131_bases
ATGATCCACAAGTCGCGCTCGCAACCGAATGCGCCGCGGCTGTCGCCGCTGCGCTACATCAAATGGCGCTGGCTGCATTT
CCGCCGCGCGTGGACCGACACGCGCTCGGACCGCATCCCGAGCTGGTCGCGCCTCTACCTGCGGACTTATCTGCATCTGC
TCGGCCTTGTGCTGCTGACCGCGCTCGTGCCGGCGCTCGCGTTGTGCATCGTGCTGTCGCCGGAAGTCGTGTGGCATTCG
TTCGACGCGCTGCCGGGCGACATCTGGATCGTGCTCGCGTTCGTGTTCGTCGCGCCGGCGCTCGCTGCGTACCGATGGAT
GCGGCCGGTCTGGTCGGATCTCGTGATGGTCCGCGAACGCGCGATCGACTTTACGGGCGGTCGCTTCAACACACGCGCAC
GCGAATCGCGCAGCGTGATCATCGGTCCGCTCGCACGTACGCTGAATGCGCTCGCGATGCGGATGGAACGCCTGATCGCC
GCGCAACGCGATTTGACGAACGGCATCTCGCACGAGTTGCGCACGCCGCTCGCGCGCGTGCGTTTCGCGCTCGAGATGCT
GCGCGAGCCCGGTTCCGAAGCCGAGTATCGCAGCGCACTCGACAGCATCGCGCAGGACGTGACCGAGCTCGACGAACTGA
TCGACATGAGCCTCACCTACGCGCGCCTCGAATACAGTTCGCTGCAGTCGAATCTCGAGATGACCGCGCTCGTCGCGTGG
TTCGAGCACCAGGTGAGCGATGCGCAGCTGCTCTATCCGGAGCGGACGATCGAATCGCGGATCGCGATCGAGTCGGACCT
GCGCGTAAGGATGGACCGGCGGCTGATGTCGTACGCGATGCGCAATCTGCTGCGCAATGCGAGCAAGTACGCGGCGTCGC
GGATCATCGTCGGGATCGCACTGCGTCACGGCAATATCGCGGTGTTCGTCGAGGACGACGGCCCCGGTGTCCCCGAGAAC
GAACGCGAGCGCATCTTCGACGCGTTCGTGCGGCTCGACCGGCGCACGGGCGGCTACGGGCTCGGGCTCGCAATTTCGCG
GCAGGTGCTGCACGCGCACAACGGACGGATCGCGGTCGTCGATCCGCTCGAGCTCGGCGGCGCGCGCTTCGAGATCAGCT
GGCCGATCTAG

Upstream 100 bases:

>100_bases
TACCAGTTCAGCAAGCACGCATGGGAATGATCGTGCGCTCGCCCACGAACGTGCGTCGGCGTGCGGCGGCTGCGTCCGGC
AGCGACGGCGGGGTGCCGCG

Downstream 100 bases:

>100_bases
ACGGCGGCCGCCGCACCGGCCGCTCTGGCGCGCACGTAAGATGCGTCACCGCATCAGCCCCGGCAGCCACAGCGAGATCG
CCGGCACGTAGGTCACGAGC

Product: OmpR family two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MIHKSRSQPNAPRLSPLRYIKWRWLHFRRAWTDTRSDRIPSWSRLYLRTYLHLLGLVLLTALVPALALCIVLSPEVVWHS
FDALPGDIWIVLAFVFVAPALAAYRWMRPVWSDLVMVRERAIDFTGGRFNTRARESRSVIIGPLARTLNALAMRMERLIA
AQRDLTNGISHELRTPLARVRFALEMLREPGSEAEYRSALDSIAQDVTELDELIDMSLTYARLEYSSLQSNLEMTALVAW
FEHQVSDAQLLYPERTIESRIAIESDLRVRMDRRLMSYAMRNLLRNASKYAASRIIVGIALRHGNIAVFVEDDGPGVPEN
ERERIFDAFVRLDRRTGGYGLGLAISRQVLHAHNGRIAVVDPLELGGARFEISWPI

Sequences:

>Translated_376_residues
MIHKSRSQPNAPRLSPLRYIKWRWLHFRRAWTDTRSDRIPSWSRLYLRTYLHLLGLVLLTALVPALALCIVLSPEVVWHS
FDALPGDIWIVLAFVFVAPALAAYRWMRPVWSDLVMVRERAIDFTGGRFNTRARESRSVIIGPLARTLNALAMRMERLIA
AQRDLTNGISHELRTPLARVRFALEMLREPGSEAEYRSALDSIAQDVTELDELIDMSLTYARLEYSSLQSNLEMTALVAW
FEHQVSDAQLLYPERTIESRIAIESDLRVRMDRRLMSYAMRNLLRNASKYAASRIIVGIALRHGNIAVFVEDDGPGVPEN
ERERIFDAFVRLDRRTGGYGLGLAISRQVLHAHNGRIAVVDPLELGGARFEISWPI
>Mature_376_residues
MIHKSRSQPNAPRLSPLRYIKWRWLHFRRAWTDTRSDRIPSWSRLYLRTYLHLLGLVLLTALVPALALCIVLSPEVVWHS
FDALPGDIWIVLAFVFVAPALAAYRWMRPVWSDLVMVRERAIDFTGGRFNTRARESRSVIIGPLARTLNALAMRMERLIA
AQRDLTNGISHELRTPLARVRFALEMLREPGSEAEYRSALDSIAQDVTELDELIDMSLTYARLEYSSLQSNLEMTALVAW
FEHQVSDAQLLYPERTIESRIAIESDLRVRMDRRLMSYAMRNLLRNASKYAASRIIVGIALRHGNIAVFVEDDGPGVPEN
ERERIFDAFVRLDRRTGGYGLGLAISRQVLHAHNGRIAVVDPLELGGARFEISWPI

Specific function: Member of the two-component regulatory system rstB/rstA. RstB functions as a membrane-associated protein kinase that phosphorylates rstA (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=290, Percent_Identity=36.551724137931, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1790346, Length=236, Percent_Identity=31.7796610169492, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1790551, Length=293, Percent_Identity=29.0102389078498, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789808, Length=244, Percent_Identity=33.1967213114754, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1788393, Length=269, Percent_Identity=28.2527881040892, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1787374, Length=332, Percent_Identity=25.3012048192771, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1788549, Length=274, Percent_Identity=26.2773722627737, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786912, Length=219, Percent_Identity=31.5068493150685, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1786600, Length=234, Percent_Identity=28.6324786324786, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1786783, Length=327, Percent_Identity=25.0764525993884, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790861, Length=207, Percent_Identity=30.4347826086957, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789403, Length=235, Percent_Identity=27.6595744680851, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789149, Length=227, Percent_Identity=28.1938325991189, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788279, Length=223, Percent_Identity=26.457399103139, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 43054; Mature: 43054

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHKSRSQPNAPRLSPLRYIKWRWLHFRRAWTDTRSDRIPSWSRLYLRTYLHLLGLVLLT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ALVPALALCIVLSPEVVWHSFDALPGDIWIVLAFVFVAPALAAYRWMRPVWSDLVMVRER
HHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIDFTGGRFNTRARESRSVIIGPLARTLNALAMRMERLIAAQRDLTNGISHELRTPLARV
HCCCCCCCCCCCHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFALEMLREPGSEAEYRSALDSIAQDVTELDELIDMSLTYARLEYSSLQSNLEMTALVAW
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FEHQVSDAQLLYPERTIESRIAIESDLRVRMDRRLMSYAMRNLLRNASKYAASRIIVGIA
HHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
LRHGNIAVFVEDDGPGVPENERERIFDAFVRLDRRTGGYGLGLAISRQVLHAHNGRIAVV
EECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCEEEE
DPLELGGARFEISWPI
CCHHHCCEEEEEECCC
>Mature Secondary Structure
MIHKSRSQPNAPRLSPLRYIKWRWLHFRRAWTDTRSDRIPSWSRLYLRTYLHLLGLVLLT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ALVPALALCIVLSPEVVWHSFDALPGDIWIVLAFVFVAPALAAYRWMRPVWSDLVMVRER
HHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIDFTGGRFNTRARESRSVIIGPLARTLNALAMRMERLIAAQRDLTNGISHELRTPLARV
HCCCCCCCCCCCHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFALEMLREPGSEAEYRSALDSIAQDVTELDELIDMSLTYARLEYSSLQSNLEMTALVAW
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FEHQVSDAQLLYPERTIESRIAIESDLRVRMDRRLMSYAMRNLLRNASKYAASRIIVGIA
HHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
LRHGNIAVFVEDDGPGVPENERERIFDAFVRLDRRTGGYGLGLAISRQVLHAHNGRIAVV
EECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCEEEE
DPLELGGARFEISWPI
CCHHHCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2646639; 1925016; 1495392 [H]