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The map label for this gene is dctS [H]

Identifier: 189353591

GI number: 189353591

Start: 1844475

End: 1846532

Strand: Reverse

Name: dctS [H]

Synonym: BMULJ_04835

Alternate gene names: 189353591

Gene position: 1846532-1844475 (Counterclockwise)

Preceding gene: 189353595

Following gene: 189353590

Centisome position: 74.66

GC content: 69.92

Gene sequence:

>2058_bases
ATGTCGGACAATACGTACTTCCCACATTCGGAAGCGGCACATGCGACGGGCATGTCGAACGGCGCTGGCGCGCCCGGCCG
TTTCGTGCAGCAGCGCTGGCGCGTGCTGTTGCCGTTCGCCGCGATCGGGCTGATCGTCGCGGGCGCATTTGCGGCGCCGT
TGCTTGCGATGCGTTTCGAACGCGCGCAGCGTCACGAGCAGCTGATTTCGGACACGCTATGGGCGCAGCAGTCGCTCGGC
TTCGAGGCGCAGCGGCTTGCCGAGGCGATGCAGATCGTCGGCACGGATCTCGCGGCCGATCCCGCGCCGGACCTGTTCAT
GCGGCGCGCAGCGGAGTTGCTGCAGCGCAGCCCCGAAGTGGTCGTGCTGTGCCGGCTCGAACGCGCGCTTGCCGCGATGC
AGTGCTTTCCCGGCGGCCGGGAAGGCGCCGCGATATCGCACGACGCGGCCGCCGCAGAATGGCGCGAGACGGCCGAGCGC
GCGCGGCGGCTCGGCCGTCCGGTCGCATCGCTTGCGGACGCACGGGAGGGCACGCCGCGCGTCGCATTGCTCGTCGTGCC
GACGCCGGGCGGCGCGGGCCGCGCGATGGCCGCGCTCGTGTCGATCGAGCGGCTGCTGACGGCGACGCTACCGTGGTGGT
TCGCGCATGAGAATGCGATCACGCTGACCGATCCGCGCGGCGACCTGATCGCGGTGCACGATCCGCGTGTCGAGGGCCGC
GGCGTCTACACGCACCGCATCGAAGTCGGCTTTGCCGATCAGACGTTCTACCTCGAAGCGAACAGCACGCGCGGGCCGCC
GTACCTGGTGCCGAACCTGCTGAGCGGCGCCGTCGCGGCGTTGTCGCTGCTGCTGGCCTGGTCGGTCTGGCGGCTGTGGC
GCGACCTCGTGCGCCGCGCTCGCGCCGAATACGCGCTGCGCGAGCAGCAGGCGCTGCGCCAGGCGATGGAGGACTCGCTG
GTGTCCGGCCTGCGCACGCGCGATCTCGATGGCCGCATTACCTACGTGAACGCCGCGTTCTGCGAGATGGTCGGATATCG
CGCGGACGAACTGATCGGCTGCGCGCCGCCGATGCCGTACTGGGCACCCGAGTTCTCCGAGCGTTCGTCGCAGCGCCACG
CGCAGCTGCTGTCGGGTACGCTGCCGCGCCACGCGTACGAATCGGTGTTCCTGCGCCGCGACGGCGAGCGACTGACGGTG
CTGATCAACGAGGCGCCGCTGCGCGACGGCACCGGCCGGCAGGTCGGCTGGACCGCGTCGATCGTCGACATCAGCGAGCA
GAAGCGCACGCAGGAGTTGCAGCGCACGCAGAACGAGCAGCTCCACCACATGTCCCGCGTGATGACGATGGGCGAGATGG
CGTCCGCGCTCGCGCACGAACTGAACCAGCCGCTCGCCGCGGCCAACAGCTACTGCACCGCGGCGTTGAACCTGATGACG
GGCGACGCGCCGCTGGACGATGCCGGCGGCCCGCGCGAACTGCTCGCGAAGGGGCGGCACCAGGTCGAGCGGGCCGGCCA
GATCATCCGGCGGGTTCAGCAGTTCGTGCGCAAGACCACGCCGTCGCTCGGGCCGGTCGCGCCCGATGCGGTGATCACCG
GCTTGTTGCCGCTCGTGCAGTTGCAGACCAGCCGCTCGGGCGAACGCGTCGACACGGTGCTCGAACCCGCGTTGCCGCCG
GTGCTGGCCGATCGCGTGCTGCTCGAACAGGTGCTGCTGAATCTCACGCGCAATGCGTTCGACGCGATGGCGCATTTGCC
GGCGAGCGAGCGGATCGTGCTGATCCGCGCGGAACGGATCGCGGCGTCGGAGGGCGATCCGGCCGTCGTGCGGATCGGCG
TGCGCGATCGCGGTCGCGGGCTGCCGGACGAAGCGCGCGACGCGCTGGAGCGGCCGTTCTTCACGACCAAGCCGGACGGC
ATGGGGATGGGCATCGCGGTCTGCCGCTCGGCGCTCGAGACGATGCATTCGCGTTTGCGATACGCGCCGTCCAGCGACGG
CGCGTGTTTCTACTTCGATTTGCGGATTACCGAAGAGTCATGCGGAACCTCTACCTGA

Upstream 100 bases:

>100_bases
CACAGGCCCGTGACAACACGGCGCAGGTTCATGGTTTGTCTCCTCGTTGAATGCTTGCCTGCACGGTCGGCAGGTGGCGC
CCAGTCTCGGTTTTCGATGC

Downstream 100 bases:

>100_bases
TCGACGACGACGACGTCATTCGCGATGCGCTCGACGCGCTGTTCCGTTCGCGCGGGCTGGCCGCGCGAGCGTTCGGCGAT
GCGCGCGCATTCCTCGATGC

Product: putative signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 685; Mature: 684

Protein sequence:

>685_residues
MSDNTYFPHSEAAHATGMSNGAGAPGRFVQQRWRVLLPFAAIGLIVAGAFAAPLLAMRFERAQRHEQLISDTLWAQQSLG
FEAQRLAEAMQIVGTDLAADPAPDLFMRRAAELLQRSPEVVVLCRLERALAAMQCFPGGREGAAISHDAAAAEWRETAER
ARRLGRPVASLADAREGTPRVALLVVPTPGGAGRAMAALVSIERLLTATLPWWFAHENAITLTDPRGDLIAVHDPRVEGR
GVYTHRIEVGFADQTFYLEANSTRGPPYLVPNLLSGAVAALSLLLAWSVWRLWRDLVRRARAEYALREQQALRQAMEDSL
VSGLRTRDLDGRITYVNAAFCEMVGYRADELIGCAPPMPYWAPEFSERSSQRHAQLLSGTLPRHAYESVFLRRDGERLTV
LINEAPLRDGTGRQVGWTASIVDISEQKRTQELQRTQNEQLHHMSRVMTMGEMASALAHELNQPLAAANSYCTAALNLMT
GDAPLDDAGGPRELLAKGRHQVERAGQIIRRVQQFVRKTTPSLGPVAPDAVITGLLPLVQLQTSRSGERVDTVLEPALPP
VLADRVLLEQVLLNLTRNAFDAMAHLPASERIVLIRAERIAASEGDPAVVRIGVRDRGRGLPDEARDALERPFFTTKPDG
MGMGIAVCRSALETMHSRLRYAPSSDGACFYFDLRITEESCGTST

Sequences:

>Translated_685_residues
MSDNTYFPHSEAAHATGMSNGAGAPGRFVQQRWRVLLPFAAIGLIVAGAFAAPLLAMRFERAQRHEQLISDTLWAQQSLG
FEAQRLAEAMQIVGTDLAADPAPDLFMRRAAELLQRSPEVVVLCRLERALAAMQCFPGGREGAAISHDAAAAEWRETAER
ARRLGRPVASLADAREGTPRVALLVVPTPGGAGRAMAALVSIERLLTATLPWWFAHENAITLTDPRGDLIAVHDPRVEGR
GVYTHRIEVGFADQTFYLEANSTRGPPYLVPNLLSGAVAALSLLLAWSVWRLWRDLVRRARAEYALREQQALRQAMEDSL
VSGLRTRDLDGRITYVNAAFCEMVGYRADELIGCAPPMPYWAPEFSERSSQRHAQLLSGTLPRHAYESVFLRRDGERLTV
LINEAPLRDGTGRQVGWTASIVDISEQKRTQELQRTQNEQLHHMSRVMTMGEMASALAHELNQPLAAANSYCTAALNLMT
GDAPLDDAGGPRELLAKGRHQVERAGQIIRRVQQFVRKTTPSLGPVAPDAVITGLLPLVQLQTSRSGERVDTVLEPALPP
VLADRVLLEQVLLNLTRNAFDAMAHLPASERIVLIRAERIAASEGDPAVVRIGVRDRGRGLPDEARDALERPFFTTKPDG
MGMGIAVCRSALETMHSRLRYAPSSDGACFYFDLRITEESCGTST
>Mature_684_residues
SDNTYFPHSEAAHATGMSNGAGAPGRFVQQRWRVLLPFAAIGLIVAGAFAAPLLAMRFERAQRHEQLISDTLWAQQSLGF
EAQRLAEAMQIVGTDLAADPAPDLFMRRAAELLQRSPEVVVLCRLERALAAMQCFPGGREGAAISHDAAAAEWRETAERA
RRLGRPVASLADAREGTPRVALLVVPTPGGAGRAMAALVSIERLLTATLPWWFAHENAITLTDPRGDLIAVHDPRVEGRG
VYTHRIEVGFADQTFYLEANSTRGPPYLVPNLLSGAVAALSLLLAWSVWRLWRDLVRRARAEYALREQQALRQAMEDSLV
SGLRTRDLDGRITYVNAAFCEMVGYRADELIGCAPPMPYWAPEFSERSSQRHAQLLSGTLPRHAYESVFLRRDGERLTVL
INEAPLRDGTGRQVGWTASIVDISEQKRTQELQRTQNEQLHHMSRVMTMGEMASALAHELNQPLAAANSYCTAALNLMTG
DAPLDDAGGPRELLAKGRHQVERAGQIIRRVQQFVRKTTPSLGPVAPDAVITGLLPLVQLQTSRSGERVDTVLEPALPPV
LADRVLLEQVLLNLTRNAFDAMAHLPASERIVLIRAERIAASEGDPAVVRIGVRDRGRGLPDEARDALERPFFTTKPDGM
GMGIAVCRSALETMHSRLRYAPSSDGACFYFDLRITEESCGTST

Specific function: Member of the two-component regulatory system dctS/dctR involved in the transport of C4-dicarboxylates. DctS functions as a membrane-associated protein kinase that phosphorylates dctR in response to environmental signals [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=382, Percent_Identity=27.4869109947644, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI1790436, Length=257, Percent_Identity=26.4591439688716, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 75193; Mature: 75062

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNTYFPHSEAAHATGMSNGAGAPGRFVQQRWRVLLPFAAIGLIVAGAFAAPLLAMRFE
CCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAQRHEQLISDTLWAQQSLGFEAQRLAEAMQIVGTDLAADPAPDLFMRRAAELLQRSPEV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCE
VVLCRLERALAAMQCFPGGREGAAISHDAAAAEWRETAERARRLGRPVASLADAREGTPR
EEEEEHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCE
VALLVVPTPGGAGRAMAALVSIERLLTATLPWWFAHENAITLTDPRGDLIAVHDPRVEGR
EEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCCEEEEECCCCCCC
GVYTHRIEVGFADQTFYLEANSTRGPPYLVPNLLSGAVAALSLLLAWSVWRLWRDLVRRA
CEEEEEEEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAEYALREQQALRQAMEDSLVSGLRTRDLDGRITYVNAAFCEMVGYRADELIGCAPPMPY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCHHHHCCCCCCCCC
WAPEFSERSSQRHAQLLSGTLPRHAYESVFLRRDGERLTVLINEAPLRDGTGRQVGWTAS
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEEE
IVDISEQKRTQELQRTQNEQLHHMSRVMTMGEMASALAHELNQPLAAANSYCTAALNLMT
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
GDAPLDDAGGPRELLAKGRHQVERAGQIIRRVQQFVRKTTPSLGPVAPDAVITGLLPLVQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
LQTSRSGERVDTVLEPALPPVLADRVLLEQVLLNLTRNAFDAMAHLPASERIVLIRAERI
HHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHH
AASEGDPAVVRIGVRDRGRGLPDEARDALERPFFTTKPDGMGMGIAVCRSALETMHSRLR
HCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
YAPSSDGACFYFDLRITEESCGTST
CCCCCCCEEEEEEEEEEHHCCCCCC
>Mature Secondary Structure 
SDNTYFPHSEAAHATGMSNGAGAPGRFVQQRWRVLLPFAAIGLIVAGAFAAPLLAMRFE
CCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAQRHEQLISDTLWAQQSLGFEAQRLAEAMQIVGTDLAADPAPDLFMRRAAELLQRSPEV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCE
VVLCRLERALAAMQCFPGGREGAAISHDAAAAEWRETAERARRLGRPVASLADAREGTPR
EEEEEHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCE
VALLVVPTPGGAGRAMAALVSIERLLTATLPWWFAHENAITLTDPRGDLIAVHDPRVEGR
EEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCCEEEEECCCCCCC
GVYTHRIEVGFADQTFYLEANSTRGPPYLVPNLLSGAVAALSLLLAWSVWRLWRDLVRRA
CEEEEEEEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAEYALREQQALRQAMEDSLVSGLRTRDLDGRITYVNAAFCEMVGYRADELIGCAPPMPY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCHHHHCCCCCCCCC
WAPEFSERSSQRHAQLLSGTLPRHAYESVFLRRDGERLTVLINEAPLRDGTGRQVGWTAS
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEEE
IVDISEQKRTQELQRTQNEQLHHMSRVMTMGEMASALAHELNQPLAAANSYCTAALNLMT
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
GDAPLDDAGGPRELLAKGRHQVERAGQIIRRVQQFVRKTTPSLGPVAPDAVITGLLPLVQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
LQTSRSGERVDTVLEPALPPVLADRVLLEQVLLNLTRNAFDAMAHLPASERIVLIRAERI
HHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHH
AASEGDPAVVRIGVRDRGRGLPDEARDALERPFFTTKPDGMGMGIAVCRSALETMHSRLR
HCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
YAPSSDGACFYFDLRITEESCGTST
CCCCCCCEEEEEEEEEEHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8455557 [H]