Click here to switch to the map view.

The map label for this gene is ldcC [H]

Identifier: 189353572

GI number: 189353572

Start: 1822791

End: 1825133

Strand: Direct

Name: ldcC [H]

Synonym: BMULJ_04816

Alternate gene names: 189353572

Gene position: 1822791-1825133 (Clockwise)

Preceding gene: 189353571

Following gene: 189353575

Centisome position: 73.7

GC content: 67.14

Gene sequence:

>2343_bases
ATGACCGCTTCCTTGACCCAACCGGCGTTCCGCCGCCTCGGCATGAAGGCGCTGCTGGTGCAGCACGACATCGACGCACG
CACGGCCACCGCACGCGCCGCGACGGCGCTCGCCGACGAGCTGCGTGCGCGGCTCGTCGACCTCGTGATCGCGACGTCCG
CGGACGATGCGCGCGCGGTGGTCGATGCCGATCCGGCAATCCAGTGCCTGCTGCTCAACTGGGAACTCGGCGACGATCCG
CAGCACACGCCCGCGCAGGCCGTGCTCGACGCGATGCGCGCACGCAATGCGACGGTGCCCGTGTTCCTGCTCGCGAGCCG
CGCGAGTGCGTCCGCGATTCCCGTCGACGCGATGCGCAAGGCCGACGACTTCATCTGGCTGCTCGAAGACACCACCGCGT
TCATCGGCGGCCGGATCGTCGCCGCGATCGAACGCTATCGCGAAACCGTACTGCCGCCGATGTTCCGCGCGCTCGCGCAG
TTCTCGCGCGTGTACGAATACTCATGGCACACGCCCGGCCACACGGGCGGCACTGCGTTCCTGAAATCGCCGGTCGGCCG
CGCCTATTTCGAGTTCTTCGGCGAATCGCTGTTCCGCTCCGACCTGTCGATCTCGGTCGGCGAACTCGGCTCGCTGCTCG
ATCACTCCGGTCCGATCGGCGACAGCGAACGCTATGCGGCACGCGTGTTCGGCGCGCACCGCACGTATCACGTGACGAAC
GGCTCGTCGATGTCGAACCGCGTGATCCTGATGGCGAGCGTCACGCGCAACCAGGTCGCGCTGTGCGACCGCAACTGCCA
CAAGTCGGCCGAGCATGCGATCACGATGTCGGGCGCGATCCCGACCTACCTGATTCCGTCGCGCAACCACTACGGCATCA
TCGGGCCGATCATGCCCGAGCGGCTGACCGCCGCCGCGGTGCGGCTCGCGATCGACGCGAACGCGCTCGTGCGCGGCCGC
GACGGTATCGACGCGACGCCCGTGCATGCGCTGATCACGAACTCGACGTACGACGGCCTCTGCTACAACGTCGCGCGCGT
CGAAGCACTGCTCGGCCAGAGCGTCGATCGGCTGCATTTCGACGAAGCATGGTACGGCTATGCGCGCTTCAACCCGATCT
ATCGCGATCGCCACGCGATGCACGGCGACCCGGCACAGCACGATGCCAGCAAGCCGACCGTGTTCGCGACGCAGTCGACG
CACAAGCTGCTCGCCGCGCTGTCGCAGGCATCCTTCATCCACGTCCGCGACGGCCGCAACCCGATCGAGCACGCGCGCTT
CAACGAGGCGTACATGATGCATGCGTCGACGTCGCCGAACTACGCGATCATCGCGTCGAACGACGTGAGCGCCGCGATGA
TGGACGGCCCCGGCGGCGAAGCGCTGACGACCGACGCGATCCGCGAGGCCGTCGCGTTCCGCCAGATGCTCGGACGCCTG
CACGCCGAATGCGCGGAGAACGACGACTGGTTCTTCAACGGCTGGCAGCCCGACACCGTCGTGGACCGCAAGACGGGCCG
GCGCATGCGCTTCCATGAAGCGGACGAGACGCTGCTCGCGACCGATCCGTCGTGCTGGGTGCTGCATCCGGGCGACGCGT
GGCACGGCTTCGGCGATATCGAGGACGACTACTGCATGCTCGACCCGATCAAGGTGTCGATCGTCACGCCGGGCATCGCG
CCGCACGGGGGGCTGATGCCGGTCGGCATTCCGGCCTCGGTCGTCACCGCGTATCTGGATCGGCACGGAATCGTGGTCGA
GAAGACCACCGACTTCACGATCCTGTTCCTGTTCTCGCTCGGCGTGACGAAGGGCAAGTGGGGCACGCTCGTCAACACGT
TGCTCGACTTCAAGCGCGACTACGACGCGAACGTGTCGCTCGAACAGGCGCTGCCCGACCTCGTCGCACGCTATCCGGAC
CGCTACCGCAAGCTCGGCCTGCGCGACCTGTGCGACCTGATGTTCGCTGCGATGAGCGATCTGAAGACGACCGAGATGAT
GTCGCGCGGCTTCTCGACGCTGCCGAAGCCGGATTTCAGCCCGGCCGAGGCGTTCGAGCATCTGGTGCATAACGACATCG
AGATGCTCGAGCTGTCGGAGATGGCAGGCCGCACCGTCGCGACCGGCGTGGTCCCGTATCCGCCCGGCATTCCGCTGCTG
ATGCCGGGCGAGAACGCGGGGCCCGCCGACGGCCCGCTGCTCGGCTACCTAAAGGCGCTCGAACAGTACGACCTGCGCTT
CCCCGGCTTCACGCACGACACGCACGGCGTCGATGTCGAGGACGGCGTGTACCGGATCGCGTGCATCAAGCTGCCGAAAC
GCGACGGCGGCAATACGCGCTGA

Upstream 100 bases:

>100_bases
CTGGATCTCCGTCGGCCGTCACCGCGCCGACATCCTTCACGCGCGCTCGCCGGCCGTTGCTGCGGGCGCCCCTGCAACCC
AGCACACGGGGGAATGACAC

Downstream 100 bases:

>100_bases
GCGCATGCGTCGCGCGCCGTCGAGCCATCGCAGGGCGGCGCGCAACATACCGGGCGACGGCCGCCGTCGGCGGACCGCCG
TCCGTCACGCGGCCGGCTGC

Product: lysine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 780; Mature: 779

Protein sequence:

>780_residues
MTASLTQPAFRRLGMKALLVQHDIDARTATARAATALADELRARLVDLVIATSADDARAVVDADPAIQCLLLNWELGDDP
QHTPAQAVLDAMRARNATVPVFLLASRASASAIPVDAMRKADDFIWLLEDTTAFIGGRIVAAIERYRETVLPPMFRALAQ
FSRVYEYSWHTPGHTGGTAFLKSPVGRAYFEFFGESLFRSDLSISVGELGSLLDHSGPIGDSERYAARVFGAHRTYHVTN
GSSMSNRVILMASVTRNQVALCDRNCHKSAEHAITMSGAIPTYLIPSRNHYGIIGPIMPERLTAAAVRLAIDANALVRGR
DGIDATPVHALITNSTYDGLCYNVARVEALLGQSVDRLHFDEAWYGYARFNPIYRDRHAMHGDPAQHDASKPTVFATQST
HKLLAALSQASFIHVRDGRNPIEHARFNEAYMMHASTSPNYAIIASNDVSAAMMDGPGGEALTTDAIREAVAFRQMLGRL
HAECAENDDWFFNGWQPDTVVDRKTGRRMRFHEADETLLATDPSCWVLHPGDAWHGFGDIEDDYCMLDPIKVSIVTPGIA
PHGGLMPVGIPASVVTAYLDRHGIVVEKTTDFTILFLFSLGVTKGKWGTLVNTLLDFKRDYDANVSLEQALPDLVARYPD
RYRKLGLRDLCDLMFAAMSDLKTTEMMSRGFSTLPKPDFSPAEAFEHLVHNDIEMLELSEMAGRTVATGVVPYPPGIPLL
MPGENAGPADGPLLGYLKALEQYDLRFPGFTHDTHGVDVEDGVYRIACIKLPKRDGGNTR

Sequences:

>Translated_780_residues
MTASLTQPAFRRLGMKALLVQHDIDARTATARAATALADELRARLVDLVIATSADDARAVVDADPAIQCLLLNWELGDDP
QHTPAQAVLDAMRARNATVPVFLLASRASASAIPVDAMRKADDFIWLLEDTTAFIGGRIVAAIERYRETVLPPMFRALAQ
FSRVYEYSWHTPGHTGGTAFLKSPVGRAYFEFFGESLFRSDLSISVGELGSLLDHSGPIGDSERYAARVFGAHRTYHVTN
GSSMSNRVILMASVTRNQVALCDRNCHKSAEHAITMSGAIPTYLIPSRNHYGIIGPIMPERLTAAAVRLAIDANALVRGR
DGIDATPVHALITNSTYDGLCYNVARVEALLGQSVDRLHFDEAWYGYARFNPIYRDRHAMHGDPAQHDASKPTVFATQST
HKLLAALSQASFIHVRDGRNPIEHARFNEAYMMHASTSPNYAIIASNDVSAAMMDGPGGEALTTDAIREAVAFRQMLGRL
HAECAENDDWFFNGWQPDTVVDRKTGRRMRFHEADETLLATDPSCWVLHPGDAWHGFGDIEDDYCMLDPIKVSIVTPGIA
PHGGLMPVGIPASVVTAYLDRHGIVVEKTTDFTILFLFSLGVTKGKWGTLVNTLLDFKRDYDANVSLEQALPDLVARYPD
RYRKLGLRDLCDLMFAAMSDLKTTEMMSRGFSTLPKPDFSPAEAFEHLVHNDIEMLELSEMAGRTVATGVVPYPPGIPLL
MPGENAGPADGPLLGYLKALEQYDLRFPGFTHDTHGVDVEDGVYRIACIKLPKRDGGNTR
>Mature_779_residues
TASLTQPAFRRLGMKALLVQHDIDARTATARAATALADELRARLVDLVIATSADDARAVVDADPAIQCLLLNWELGDDPQ
HTPAQAVLDAMRARNATVPVFLLASRASASAIPVDAMRKADDFIWLLEDTTAFIGGRIVAAIERYRETVLPPMFRALAQF
SRVYEYSWHTPGHTGGTAFLKSPVGRAYFEFFGESLFRSDLSISVGELGSLLDHSGPIGDSERYAARVFGAHRTYHVTNG
SSMSNRVILMASVTRNQVALCDRNCHKSAEHAITMSGAIPTYLIPSRNHYGIIGPIMPERLTAAAVRLAIDANALVRGRD
GIDATPVHALITNSTYDGLCYNVARVEALLGQSVDRLHFDEAWYGYARFNPIYRDRHAMHGDPAQHDASKPTVFATQSTH
KLLAALSQASFIHVRDGRNPIEHARFNEAYMMHASTSPNYAIIASNDVSAAMMDGPGGEALTTDAIREAVAFRQMLGRLH
AECAENDDWFFNGWQPDTVVDRKTGRRMRFHEADETLLATDPSCWVLHPGDAWHGFGDIEDDYCMLDPIKVSIVTPGIAP
HGGLMPVGIPASVVTAYLDRHGIVVEKTTDFTILFLFSLGVTKGKWGTLVNTLLDFKRDYDANVSLEQALPDLVARYPDR
YRKLGLRDLCDLMFAAMSDLKTTEMMSRGFSTLPKPDFSPAEAFEHLVHNDIEMLELSEMAGRTVATGVVPYPPGIPLLM
PGENAGPADGPLLGYLKALEQYDLRFPGFTHDTHGVDVEDGVYRIACIKLPKRDGGNTR

Specific function: ADC can be found in two forms:biodegradative and biosynthetic. The biodegradative form may play a role in regulating pH by consuming proteins [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI221142684, Length=758, Percent_Identity=49.2084432717678, Blast_Score=801, Evalue=0.0,
Organism=Escherichia coli, GI1790573, Length=725, Percent_Identity=38.7586206896552, Blast_Score=518, Evalue=1e-148,
Organism=Escherichia coli, GI1786384, Length=739, Percent_Identity=37.3477672530447, Blast_Score=504, Evalue=1e-144,
Organism=Escherichia coli, GI87082193, Length=692, Percent_Identity=32.9479768786127, Blast_Score=348, Evalue=1e-96,
Organism=Escherichia coli, GI1786909, Length=703, Percent_Identity=31.8634423897582, Blast_Score=346, Evalue=3e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 85680; Mature: 85549

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASLTQPAFRRLGMKALLVQHDIDARTATARAATALADELRARLVDLVIATSADDARAV
CCCCCCCHHHHHCCHHHEEHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEE
VDADPAIQCLLLNWELGDDPQHTPAQAVLDAMRARNATVPVFLLASRASASAIPVDAMRK
ECCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHC
ADDFIWLLEDTTAFIGGRIVAAIERYRETVLPPMFRALAQFSRVYEYSWHTPGHTGGTAF
CCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LKSPVGRAYFEFFGESLFRSDLSISVGELGSLLDHSGPIGDSERYAARVFGAHRTYHVTN
HHCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEEEC
GSSMSNRVILMASVTRNQVALCDRNCHKSAEHAITMSGAIPTYLIPSRNHYGIIGPIMPE
CCCCCCCEEEEEECCCCCEEHHCCHHCCCHHCEEEECCCCCEEEECCCCCCEEECCCCHH
RLTAAAVRLAIDANALVRGRDGIDATPVHALITNSTYDGLCYNVARVEALLGQSVDRLHF
HHHHHHHHEEECCCEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHCC
DEAWYGYARFNPIYRDRHAMHGDPAQHDASKPTVFATQSTHKLLAALSQASFIHVRDGRN
CHHHCCHHHCCCHHHCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHCCEEEEECCCC
PIEHARFNEAYMMHASTSPNYAIIASNDVSAAMMDGPGGEALTTDAIREAVAFRQMLGRL
HHHHCCCCCEEEEEECCCCCEEEEECCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHH
HAECAENDDWFFNGWQPDTVVDRKTGRRMRFHEADETLLATDPSCWVLHPGDAWHGFGDI
HHHHCCCCCCEECCCCCCCCCCCCCCCCEEEECCCCEEEECCCCEEEECCCCCCCCCCCC
EDDYCMLDPIKVSIVTPGIAPHGGLMPVGIPASVVTAYLDRHGIVVEKTTDFTILFLFSL
CCCEEEECCEEEEEEECCCCCCCCEEECCCCHHHHHHHHHHCCEEEEECCCEEEEEEEHH
GVTKGKWGTLVNTLLDFKRDYDANVSLEQALPDLVARYPDRYRKLGLRDLCDLMFAAMSD
CCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHH
LKTTEMMSRGFSTLPKPDFSPAEAFEHLVHNDIEMLELSEMAGRTVATGVVPYPPGIPLL
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCEEECCCCCCCCCCCEE
MPGENAGPADGPLLGYLKALEQYDLRFPGFTHDTHGVDVEDGVYRIACIKLPKRDGGNTR
ECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCC
>Mature Secondary Structure 
TASLTQPAFRRLGMKALLVQHDIDARTATARAATALADELRARLVDLVIATSADDARAV
CCCCCCHHHHHCCHHHEEHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEE
VDADPAIQCLLLNWELGDDPQHTPAQAVLDAMRARNATVPVFLLASRASASAIPVDAMRK
ECCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHC
ADDFIWLLEDTTAFIGGRIVAAIERYRETVLPPMFRALAQFSRVYEYSWHTPGHTGGTAF
CCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LKSPVGRAYFEFFGESLFRSDLSISVGELGSLLDHSGPIGDSERYAARVFGAHRTYHVTN
HHCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEEEC
GSSMSNRVILMASVTRNQVALCDRNCHKSAEHAITMSGAIPTYLIPSRNHYGIIGPIMPE
CCCCCCCEEEEEECCCCCEEHHCCHHCCCHHCEEEECCCCCEEEECCCCCCEEECCCCHH
RLTAAAVRLAIDANALVRGRDGIDATPVHALITNSTYDGLCYNVARVEALLGQSVDRLHF
HHHHHHHHEEECCCEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHHCC
DEAWYGYARFNPIYRDRHAMHGDPAQHDASKPTVFATQSTHKLLAALSQASFIHVRDGRN
CHHHCCHHHCCCHHHCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHCCEEEEECCCC
PIEHARFNEAYMMHASTSPNYAIIASNDVSAAMMDGPGGEALTTDAIREAVAFRQMLGRL
HHHHCCCCCEEEEEECCCCCEEEEECCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHH
HAECAENDDWFFNGWQPDTVVDRKTGRRMRFHEADETLLATDPSCWVLHPGDAWHGFGDI
HHHHCCCCCCEECCCCCCCCCCCCCCCCEEEECCCCEEEECCCCEEEECCCCCCCCCCCC
EDDYCMLDPIKVSIVTPGIAPHGGLMPVGIPASVVTAYLDRHGIVVEKTTDFTILFLFSL
CCCEEEECCEEEEEEECCCCCCCCEEECCCCHHHHHHHHHHCCEEEEECCCEEEEEEEHH
GVTKGKWGTLVNTLLDFKRDYDANVSLEQALPDLVARYPDRYRKLGLRDLCDLMFAAMSD
CCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHH
LKTTEMMSRGFSTLPKPDFSPAEAFEHLVHNDIEMLELSEMAGRTVATGVVPYPPGIPLL
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCEEECCCCCCCCCCCEE
MPGENAGPADGPLLGYLKALEQYDLRFPGFTHDTHGVDVEDGVYRIACIKLPKRDGGNTR
ECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8383109; 7610040; 9278503; 2830169; 4204273 [H]